Clinical Trials on Sarcoma, Bone Tumor in United Kingdom

Total 20224 results

European Organisation for Research and Treatment...

Terminated

Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Sarcoma

United Kingdom
Celgene

Completed

Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

Melanoma | Sarcoma, Soft Tissue | Cancer | Fibrosarcoma | Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma | Neoplasm | Malignant Melanoma | Tumors | Histiocytoma | Dermatofibrosarcoma | Sarcoma, Ewing's | Neoplasia | Ewing's Sarcoma | Ewing's Tumor | Sarcomas, Epitheliod | Sarcoma, Spindle Cell | Clinical Oncology | Oncology,... and other conditions

United States, Canada, Spain, France, United Kingdom, Italy, Switzerland
Dana-Farber Cancer Institute
Harvard University; Conquer Cancer Foundation; Alex's Lemonade Stand Foundation; Sam Day Foundation

Recruiting

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing Sarcoma of Bone | Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of Bone | High-grade Osteosarcoma | Ewing Sarcoma of Soft Tissue | Peripheral Primitive Neuroectodermal Tumor of Soft Tissue

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
St. Jude Children's Research Hospital
University of Florida; University of Tennessee; Nemours Children's Clinic

Active, not recruiting

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

Desmoplastic Small Round Cell Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Ewing Sarcoma of Bone or Soft Tissue | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Mayo Clinic

Completed

18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor and other conditions

United States
National Cancer Institute (NCI)

Completed

Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma

Ewing Sarcoma of Bone | Peripheral Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Extraosseous Ewing Sarcoma

United States
Onxeo
Spectrum Pharmaceuticals, Inc

Completed

A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas

Dose Escalation: Solid Tumors | MTD: Soft Tissue Sarcomas

Denmark, United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Biomarkers in Saliva Samples From Patients With Ewing Sarcoma

Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor (PNET)

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Tumor Samples From Patients With Ewing Sarcoma

Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Memorial Sloan Kettering Cancer Center
University of Oregon; University College, London; New York Presbyterian Hospital and other collaborators

Completed

Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone Tumors

Sarcoma | Bone Tumor

United States
Eli Lilly and Company

Completed

A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma

Leiomyosarcoma | Rhabdomyosarcoma | Synovial Sarcoma | Ewing's Sarcoma /Peripheral Neuroectodermal Tumor (PNET) | Adipocytic Sarcoma

United States, Germany, Poland, Belgium, Spain, France, Netherlands
PharmaMar

Completed

Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapy

Ewing's Sarcoma | Primitive Neuroectodermal Tumor (PNET) | Askin's Tumor of the Chest Wall | Extraosseous Ewing's Sarcoma (EOE)

France, United States, Italy
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

Lung Metastases | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Childhood Synovial Sarcoma | Childhood Desmoplastic Small Round Cell Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Askin Tumor

United States, Canada, Puerto Rico, Australia, New Zealand, Switzerland
National Cancer Institute (NCI)

Completed

IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor or Other Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Istituto Ortopedico Rizzoli
Regione Emilia-Romagna

Completed

Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irinotecan (MGMTLiberati)

Ewing Sarcoma Family of Tumors

United Kingdom, Italy
Birmingham Women's and Children's NHS Foundation...

Completed

Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Rhabdomyosarcoma | Metastatic Osteosarcoma | Pulmonary Metastasis | Metastatic Ewing Sarcoma | Pediatric Renal Tumor | Non-Rhabdo. Soft Tissue Sarcoma

United Kingdom
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07)

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions

United States
AstraZeneca

Completed

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United Kingdom
Gradalis, Inc.

Terminated

A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide (VITA)

Sarcoma | Neoplasms | Neoplasms, Connective and Soft Tissue | Neoplasms by Histologic Type | Sarcoma, Ewing | Neoplasms, Bone Tissue | Neoplasms, Connective Tissue | Ewing Sarcoma | Rare Diseases | Ewing's Tumor Metastatic | Ewing Family of Tumors | Ewing's Sarcoma Metastatic | Ewing's Tumor Recurrent

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

Localized Extraskeletal Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor of Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues

United States, Canada, Saudi Arabia, Australia, New Zealand, Puerto Rico
National Cancer Institute (NCI)

Completed

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

Recurrent Uterine Corpus Sarcoma | Chondrosarcoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult... and other conditions

United States
National Cancer Institute (NCI)

Completed

A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors

Sarcoma | Neuroepithelioma | Osteosarcoma | Neuroectodermal Tumor, Primitive | Sarcoma, Ewing's

United States
Mohammed Milhem, MBBS
University of Iowa; University of Iowa Adolescent and Young Adult (AYA) Cancer... and other collaborators

Terminated

Gemcitabine Plus Ascorbate for Sarcoma in Adults

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma | Metastatic Bone Tumor | Unresectable Soft Tissue Sarcoma

United States
Gradalis, Inc.

Completed

Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's Sarcoma

Sarcoma | Rare Diseases | Ewing's Tumor Metastatic | Ewing's Sarcoma | Ewing Family of Tumors | Ewing's Sarcoma Metastatic | Ewing's Tumor Recurrent

United States
Pfizer

Completed

Study Of Anti-IGF-IR CP-751,871 In Patients With Solid Tumors

Sarcoma, Ewing's

United States, United Kingdom
Mohammed Milhem, MBBS
University of Iowa

Recruiting

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma | Metastatic Bone Tumor | Unresectable Soft Tissue Sarcoma

United States
Sarcoma Alliance for Research through Collaboration
Bristol-Myers Squibb

Completed

Trial of Dasatinib in Advanced Sarcomas

Chondrosarcoma | Chordoma | Hemangiopericytoma | Rhabdomyosarcoma | Sarcoma, Alveolar Soft Part | Epithelioid Sarcoma | Gastrointestinal Stromal Tumor (GIST) | Giant Cell Tumor of Bone | Sarcoma, Ewing's | Malignant Peripheral Nerve Sheath Tumors

United States
HMeany

Completed

Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors

Osteosarcoma | Neuroblastoma | Brain Tumors | Ewing's Sarcoma Family of Tumors | Rhabdomyosarcoma and Other Soft Tissue Sarcomas

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Radiation Therapy in Treating Patients With Ewing's Sarcoma, Peripheral Primitive Neuroectodermal Tumor, or Rhabdomyosarcoma

Sarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Metastatic Malignant Neoplasm in the Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues | Metastatic Malignant Neoplasm in the Lung | Metastatic Ewing Sarcoma | Metastatic Malignant Neoplasm in the Bone Marrow | Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone

United States, Canada, Puerto Rico
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Pleomorphic Liposarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Metastatic Unresectable Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma | Metastatic... and other conditions

United States
Daiichi Sankyo, Inc.

Completed

Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Small Round Cell Tumor

Sarcoma

United States, Canada
National Cancer Institute (NCI)

Completed

Ixabepilone in Treating Young Patients With Refractory Solid Tumors

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Ewing Sarcoma... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors

Recurrent Ewing Sarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Peripheral Primitive Neuroectodermal Tumor

United States, Canada
QSAM Therapeutics, Inc.

Recruiting

A Dose Finding Study to Treat Bone Tumor(s)

Bone Cancer | Solid Tumor | Bone Tumor | Metastatic Cancer to the Bone | Metastatic Tumor to the Bone

United States
European Organisation for Research and Treatment...
Amgen

Terminated

Reduced Dose-density of Denosumab for Unresectable GCTB (REDUCE)

Bone Giant Cell Tumor

Spain, United Kingdom, Italy, Netherlands
Baylor College of Medicine
Cancer Prevention Research Institute of Texas; The Methodist Hospital Research... and other collaborators

Active, not recruiting

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Refractory Neuroblastoma | Uveal Melanoma | Relapsed Ewing Sarcoma | Relapsed Osteosarcoma | Relapsed Neuroblastoma | Relapsed Rhabdomyosarcoma | Phyllodes Breast Tumor

United States
Genzyme, a Sanofi Company
Sanofi

Completed

A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone

Neuroblastoma | Brain Tumors | Ewing's Sarcoma/Soft Tissue Sarcoma

Belgium, Czechia, Denmark, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Spain, United Kingdom
University Hospital Muenster
Medical Research Council

Unknown

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Sarcoma

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Evaluating Dactinomycin and Vincristine in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Ewing Sarcoma of Bone | Ewing Sarcoma | Childhood Acute Lymphoblastic Leukemia | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Rhabdomyosarcoma | Childhood Soft Tissue Sarcoma | Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor...

United States, Australia, Canada
The Netherlands Cancer Institute
Royal Marsden NHS Foundation Trust

Terminated

Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients (PASART-2)

Sarcoma | Soft Tissue Sarcomas

United Kingdom, Netherlands
National Cancer Institute (NCI)

Completed

Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma

Sarcoma | Neuroectodermal Tumors, Primitive, Peripheral | Neuroblastoma | Rhabdomyosarcoma-Embryonal | Rhabdomyosarcoma- Alveolar

United States
Children's Oncology Group
National Cancer Institute (NCI); SWOG Cancer Research Network

Completed

Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor

Sarcoma

United States, Canada, Australia, Switzerland, Puerto Rico, Netherlands, New Zealand
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
St. Jude Children's Research Hospital

Active, not recruiting

Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas

Sarcoma, Soft Tissue | Osteosarcoma | Sarcoma, Ewing | Rhabdomyosarcoma | Sarcoma, Bone | Non-rhabdomyosarcoma Soft-tissue Sarcoma

United States
Pfizer

Completed

Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumors

Ewing's Sarcoma Family of Tumors

Spain, France, United States, Italy, Australia, Germany, United Kingdom, Israel, Canada, Brazil, Chile

Clinical Trials on Sarcoma, Bone Tumor in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Greece

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations