Clinical Trials on Seizure Disorder

Total 144780 results

Eisai Inc.

Completed

Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures

Partial Seizures

China
Eisai Inc.

Completed

Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug

Partial Seizures

Italy
National Institute of Mental Health (NIMH)

Completed

Clinical and Immunological Investigations of Subtypes of Autism

Seizures | Autism Spectrum Disorders

United States
Neurelis, Inc.

Completed

Repeat Dose Safety Study of NRL-1 in Epilepsy Subjects

Acute Repetitive Seizures | Breakthrough Seizures

United States
UCB Japan Co. Ltd.

Completed

A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures

Epilepsy | Generalized Tonic-clonic Seizures

Japan
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures

Electroencephalographic Neonatal Seizures

Belgium, France, Germany, Ireland, United Kingdom, Czechia, Italy
University Health Network, Toronto

Terminated

Intra Cranial EEG Activity During Dexmedetomidine Sedation

Complex Partial Seizures

Canada
Mohawk College
Hamilton Health Sciences Corporation; Ryerson University

Completed

Detection of Motor Seizures Using WBAN (DMS-WBAN)

Seizures, Tonic-Clonic

Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open-Label Study Of Pregabalin In Subjects With Refractory Partial Seizures

Epilepsy

Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Lyrica (Pregabalin) Administered as an Add-on Therapy for Partial Seizures (LEADER). (LEADER)

Epilepsy

Greece
University of South Alabama

Withdrawn

Safety Study of Rufinamide Given as an add-on Therapy to Treat Patients With Seizures

Refractory Partial Seizures

United States
Nobelpharma

Completed

Long-term Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures

Partial Onset Seizures

Japan
Eisai Co., Ltd.

Completed

A Long-term Extension Study of E2007 in Patients With Refractory Partial Seizures Uncontrolled With Other Anti-Epileptic Drugs (AEDs)

Refractory Partial Seizures

Japan
UCB BIOSCIENCES, Inc.
PRA Health Sciences

Terminated

Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures

Nonconvulsive Electrographic Seizures

United States
Lawson Health Research Institute

Completed

Seizures After Cardiac Surgery -- A Study With Continuous EEG Monitoring

Non-convulsive Seizures

Canada
UCB Pharma

Completed

Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures

Epilepsy

France, Poland, United Kingdom, Germany, Spain, Finland, Australia, Russian Federation, Hungary, Lithuania, Sweden, Czechia, Croatia
Eisai Inc.

Completed

Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Refractory Partial Seizures

Hong Kong, Italy, Australia, Spain, Portugal, Taiwan, India, Thailand, Hungary, Poland, Bulgaria, Serbia, Russian Federation, Korea, Republic of, Ukraine, Romania, Latvia, Lithuania, Germany, Estonia, Czech Republic, Philippines, Ma...
Eisai Co., Ltd.
Eisai Limited

Completed

Exploring the Safety And Tolerability of Doses of E2007 up to a Maximum of 12 mg In Patients With Refractory Partial Seizures

Epilepsy

Latvia
Novartis

Withdrawn

Evaluate the Efficacy of BGG492 as Adjunctive Treatment in Patients With Refractory Partial Onset Seizures

Partial Onset Seizures

United States, Austria, Spain, Estonia, Bulgaria, Latvia, Canada, India, Belgium, Lithuania, Romania
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
UCB Pharma

Completed

An Open Label Study of L059 (Levetiracetam) in Japanese Epilepsy Subjects With Generalized Tonic-clonic Seizures

Epilepsy | Generalized Tonic-clonic Seizures

Japan
Eisai Inc.

Completed

Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy

Epilepsy | Primary Generalized Tonic-Clonic Seizures | Partial-Onset Seizures
Biogen

Completed

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy (OPUS)

Epilepsy, Focal Seizures, Partial Seizures

United States
University Hospital, Bonn

Completed

Magnetic Seizure Therapy (MST) for Treatment Resistant Major Depression

Major Depression

Germany
Janssen Research & Development, LLC

Completed

A Study to Investigate JNJ-40411813 in Combination With Levetiracetam or Brivaracetam in Epilepsy

Focal Onset Seizures

Germany, Korea, Republic of, Belgium, United States, Russian Federation, Poland, Ukraine, Spain
McMaster University

Completed

Detecting Non-convulsive Seizures in the Paediatric Intensive Care Unit

Non-convulsive Seizures

Canada
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part A

Epilepsy | Focal Seizures

United Kingdom, Spain, Czechia
Novartis Pharmaceuticals

Completed

Phase II BGG492 Capsule Extension for Partial Epilepsy

Partial Onset Seizures

Germany, United States, Hungary, Korea, Republic of, Poland, Slovakia
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures

Partial Onset Seizures

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pregabalin Versus Levetiracetam In Partial Seizures

Partial Seizures

Costa Rica, Spain, Greece, Korea, Republic of, Panama, Turkey, Philippines, Belgium, Taiwan, Germany, India, Italy, Colombia, Bulgaria, Russian Federation, France, Czechia, Lithuania, Mexico, Peru, Venezuela
University of Michigan
Patient-Centered Outcomes Research Institute; Massachusetts General Hospital; Children's Hospital of Philadelphia and other collaborators

Completed

Continued Anticonvulsants After Resolution of Neonatal Seizures: a Patient-centered Comparative Effectiveness Study

Neonatal Seizures

United States
Eisai Limited

Completed

A Study of Perampanel as Add-on Therapy in Adult and Adolescent Participants With Focal Seizures

Partial Seizures
All India Institute of Medical Sciences, Bhubaneswar

Completed

Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures

Seizures, Focal

India
University of Rochester

Terminated

Prophylactic Phenobarbital After Neonatal Seizures (PROPHENO)

Neonatal Seizures

United States
Stephanie Merhar, MD

Terminated

Efficacy of Keppra for Neonatal Seizures

Neonatal Seizures

United States
HaEmek Medical Center, Israel

Completed

The Relevance of Performing Lumbar Puncture in Infants Aged 3 to 12 Months With First Episode of Febrile Convulsion

Febrile Convulsions

Israel
Novartis

Completed

Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures

Epilepsy, Partial Seizures

Russian Federation
Supernus Pharmaceuticals, Inc.

Active, not recruiting

BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (FIAS)

Focal Impaired Awareness Seizures

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Heart Rate Variability (HRV) Analysis in Patients With Nocturnal Epileptic Seizures

Epilepsy | Autonomic Nervous System | Heart Rate | Nocturnal Seizures

United Kingdom
New York State Psychiatric Institute

Completed

Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults (MSTvsEST)

Depression | Bipolar Disorder | Major Depressive Episode

United States
Eisai Inc.

Completed

A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)

Partial Onset Seizures

Germany, Sweden, Norway, Austria, Denmark
University of Manitoba

Completed

Treating Non-epileptic Seizures Using Magnetic Brain Stimulation

Nonepileptic Seizures
Equilibre Biopharmaceuticals B.V.

Terminated

Study of EQU-001 for Uncontrolled Focal Onset Seizures

Focal Onset Seizures

United States, Israel
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part B

Epilepsy | Focal Seizures

Italy, Poland, United Kingdom, Spain, Hungary, Czechia
Eisai Co., Ltd.

Completed

Study for Verification of Efficacy and Safety for Perampanel Monotherapy in Untreated Participants With Partial Onset Seizures (Including Secondarily Generalized Seizures (FREEDOM Study)

Partial Onset Seizures

Japan, Korea, Republic of
Eisai Co., Ltd.

Completed

A Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset Seizures

Partial-onset Seizures

Korea, Republic of, Japan, Australia, China, Malaysia, Taiwan, Thailand
Eisai Inc.

Completed

Rufinamide Given as Adjunctive Therapy in Participants With Refractory Partial Seizures

Epilepsy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.

Partial Onset Seizures

Korea, Republic of, Taiwan, Lebanon, United States, Malaysia, China, Spain, Turkey, Israel, Russian Federation, France, Belarus, Bulgaria, Germany, Hungary, Philippines, Romania, Serbia, Ukraine, Greece, Bosnia and Herzegovina, Be... and more

Clinical Trials on Seizure Disorder

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