Clinical Trials on Severe Aortic Valve Disease

Total 7164 results

Turku University Hospital
Vifor Pharma

Recruiting

Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery (PREFER-CABG)

Coronary Artery Disease | Postoperative Complications | Aortic Valve Stenosis | Aortic Aneurysm, Thoracic | Mitral Valve Disease

Finland
LianBio LLC

Completed

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

Hypertrophic Cardiomyopathy

China
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM (VANISH)

Hypertrophic Cardiomyopathy

United States, Canada
Sunnybrook Health Sciences Centre

Completed

Pilot Study of Cognitive and Functional Outcomes Following TAVI

Aortic Stenosis

Canada
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Single Perclose Escalation Technique for Vascular Closure in TAVR

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Spain
Fundación EPIC

Recruiting

Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication

Aortic Valve Stenosis | Structural Valve Deterioration

Spain
Medstar Health Research Institute

Recruiting

Transcatheter Aortic Prosthesis Function: A Long-term Follow-up Study

Aortic Valve Replacement

United States
Corcym S.r.l
LivaNova

Completed

Behavior of Valve Leaflets Following Aortic Valve Implant (BELIEVE)

Aortic-valve Replacement

United States, Canada
University Hospital, Basel, Switzerland

Completed

10 Versus 20 Minutes Treatment of Human Pericardium With Glutaraldehyde in OZAKI Procedure (10vs20-OZAKI)

Aortic Valve Surgery

Switzerland
University Hospital, Clermont-Ferrand
Ministry of Health, France; Abbott Medical Devices; Edwards Lifesciences; Sorin...

Unknown

Comparison Between Three Types of Stented Pericardial Aortic Valves

Aortic Valve Replacement

France
BOIRON
Hospices Civils de Lyon

Completed

Homoeopathic Association in Aortic Valve Surgery (OMEO)

Aortic Valve Replacement

France
Carilion Clinic

Terminated

Radial Versus Femoral Secondary Access During TAVI (R-TAVI)

Aortic Stenosis | Aortic Valve Disease | Vascular Access Complication

United States
Therenva
Centre Hospitalier Universitaire Dijon; University Hospital, Brest; Rennes University... and other collaborators

Unknown

Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation (COM-ENDO)

Aortic Aneurysm | Iliac Artery Stenosis | Iliac Aneurysm | Stenoses, Aortic

France
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Avr Thrombosis OutcoMe Study (ATOM)

Aortic Stenosis

United Kingdom
National and Kapodistrian University of Athens
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation

Aortic Valve Disease | Transcatheter Aortic Valve Implantation | TAVI

Belgium, Greece
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; University of Colorado, Denver; Emory University and other collaborators

Not yet recruiting

Promoting Shared Decision Making for Severe Aortic Stenosis (IMPACT SDM)

Aortic Stenosis

United States
University of Edinburgh

Recruiting

The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) Programme (SALTIRE)

Aortic Stenosis

United Kingdom
Edwards Lifesciences

Active, not recruiting

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis (P3)

Aortic Stenosis

United States, Australia, Japan, Canada, New Zealand
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; West China Hospital; Second Affiliated... and other collaborators

Active, not recruiting

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic Stenosis

Aortic Stenosis

China
Edwards Lifesciences

Active, not recruiting

A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan)

Aortic Stenosis

Japan
Edwards Lifesciences

Active, not recruiting

SAPIEN 3 Ultra EU PMS

Aortic Stenosis | Aortic Valve Stenosis

Portugal, Spain, Switzerland, Italy, United Kingdom, Finland, France, Germany, Austria, Norway
Avicena LLC

Withdrawn

Vivio AS (Aortic Stenosis) Algorithm Optimization Study

Aortic Stenosis

United States
Mayo Clinic

Completed

Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic Stenosis (TAVR-FRAILTY)

Aortic Stenosis

United States
Segeberger Kliniken GmbH

Completed

A Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: The CHOICE Trial (CHOICE)

Aortic Stenosis

Germany
Institute of Cardiology, Warsaw, Poland

Unknown

"Cardiac Rehabilitation in Patients With Hypertrophic Cardiomyopathy".

Cardiac Rehabilitation

Poland
Asan Medical Center
Merck Sharp & Dohme LLC

Terminated

Effect of Bisoprolol on Progression of Aortic Stenosis (BLAST)

Aortic Stenosis

Korea, Republic of
University Hospital, Toulouse

Completed

The Plasma Serotonin and Aortic Stenosis: a Pilot Study. (SERAOPI)

Aortic Stenosis

France
Seoul St. Mary's Hospital

Unknown

18F-NaF Uptake and Aortic Stenosis Progression

Aortic Stenosis
Duke University

Terminated

Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis (AS-BNP)

Aortic Stenosis

United States
Rigshospitalet, Denmark

Unknown

Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Aortic Stenosis

Denmark
The Cleveland Clinic

Terminated

Speckle Tracking Imaging in Patients With Low Ejection Fraction Aortic Stenosis (SPArKLE-AS) (SPArKLE-AS)

Aortic Stenosis

United States
RWTH Aachen University

Completed

Vitamin K Supplement for Inhibition of the Progress in Aortic Valve Calcification (08-002)

Aortic Valve Calcification

Germany
Venus MedTech (HangZhou) Inc.

Unknown

Safety and Performance of TAVI of Venus MedTech Aortic Valve Prosthesis (Venus-A)

Aortic Valve Stenosis | Aortic Valve Calcification

China
Modarres Hospital

Completed

Comparison of Aortic Root Dimension Changes During Cardiac Cycle Between the Patients With and Without Aortic Valve Calcification Using ECG-gated 64-slice and Dual-source 256-slice Computed Tomography Scanners: Results of a Multicenter Study

Aortic Valve Calcification

Iran, Islamic Republic of
Hospital Universitari Son Dureta
Laboratorios BIOMED SA

Unknown

Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications (CALCIFICA)

Aortic Stenosis | Heart Valve Disease

Spain
Sahajanand Medical Technologies Limited
Qmed Consulting A/S

Not yet recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis

Denmark
Fundación EPIC

Recruiting

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation (FAST TRACK)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases

Spain
Ole De Backer

Recruiting

Re-hospitalisation After Transcatheter Aortic Valve Implantation (HOSPITAVI)

Aortic Valve Stenosis | Aortic Valve Disease

Denmark
Guilherme Attizzani, MD

Recruiting

MRI in Transcatheter Aortic Valve Replacement Patients (MRI in TAVR)

Aortic Valve Stenosis

United States
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital

Recruiting

RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (DOUBLE-CHOICE)

Aortic Valve Stenosis

Germany
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Hamburg AoRtic Valve cOhoRt (HARbOR)

Aortic Valve Stenosis

Germany
Seung-Jung Park
CardioVascular Research Foundation, Korea

Recruiting

Evaluation of Effectiveness and Safety of Aortic Valve Replacement in Routine Clinical Practice (IRIS AVR)

Aortic Valve Stenosis | Aortic Valve Disease

Korea, Republic of
Ho-Jin Kim
CardioVascular Research Foundation, Korea

Recruiting

ASAN Medical Center Aortic Valve Replacement Registry (ASAN-AVR)

Aortic Valve Stenosis

Korea, Republic of
Corcym S.r.l

Active, not recruiting

PERCEVAL S Valve Clinical Study for Chinese Registration (PERFECT)

Aortic Valve Stenosis | Aortic Valve Disease

China
University Hospital, Montpellier
Edwards Lifesciences

Completed

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3 (DIRECTAVI)

Aortic Valve Stenosis

France
University Hospital, Basel, Switzerland

Completed

Sizing of the PERCEVAL® Sutureless Aortic Valve Prosthesis Using the CT: a Feasibility Study

Aortic Valve Stenosis

Switzerland
Aesculap AG
B.Braun Surgical SA

Completed

PremiCron Suture for Cardiac Valve Repair (PremiValve)

Aortic Valve Stenosis

Spain, Germany
Medtronic Cardiovascular

Completed

The Medtronic TAVR 2.0 US Clinical Study

Aortic Valve Stenosis

United States
University Hospital, Bordeaux

Completed

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) (TICTAVI)

Aortic Valve Stenosis

France
Leipzig Heart Institute GmbH

Completed

Randomized Comparison of Catheter-based Strategies for Interventional Access Site Closure During Transfemoral Transcatheter Aortic Valve Implantation (CHOICE-CLOSURE)

Aortic Valve Stenosis

Germany

Clinical Trials on Severe Aortic Valve Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Iran

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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