Clinical Trials on Sex Chromosome Disorders

Total 144653 results

Renato Melaragno

Unknown

Phase II Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Chronic Myeloid Leukemia (CML) Philadelphia Chromosome-positive (Ph+)

Chronic Myeloid Leukemia (CML) With Philadelphia Chromosome-positive (Ph+)

Brazil
Bristol-Myers Squibb

Completed

A Study of Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia

Myeloid Leukemia, Chronic

Japan
Northwestern University
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM (SMART)

Hiv | Adolescent Behavior | Sex, Safe

United States
University of Toronto
Natural Sciences and Engineering Research Council, Canada

Completed

Influence of Sex and Training on de Novo Muscle Protein Synthesis (TUT)

Resistance Exercise | Amino Acids | Dietary Protein | Sex

Canada
Tianjin Medical University General Hospital

Unknown

Pharmacokinetics and Pharmacodynamics of Rocuronium in Closed-Loop Infusion System

TOF | Sex
University of the Basque Country (UPV/EHU)

Completed

Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach

Depression, Anxiety | Alcohol Abuse | Unsafe Sex | Sexual Compulsivity

Spain
Vanderbilt University Medical Center
Vanderbilt Kennedy Center

Recruiting

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Alzheimer Disease | Down Syndrome | Down Syndrome, Partial Trisomy 21

United States
Nanfang Hospital of Southern Medical University
Xiangya Hospital of Central South University; Peking University People's Hospital and other collaborators

Unknown

Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML

MRD | Risk-directed Therapy | Cytogenetic Abnormality | Molecular Abnormality

China
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Measuring Free-living Energy Expenditure Using Direct Calorimetry

Adiposity | Temperature | Age | Clothing | Sex

United States
University of Washington

Completed

Evaluating Personalized Information and Choices (EPIC)

Risk-Taking | Sex Behavior | Underage Alcohol Use | Feedback, Psychological
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | Acute Lymphoblastic Leukemia in Remission

United States
Cancer Institute and Hospital, Chinese Academy...

Unknown

Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia | B-cell Childhood Acute Lymphoblastic Leukemia | Philadelphia Chromosome, Ph^1^, Absent

China
Bayer

Completed

A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women

Hot Flashes | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Canada
Mayo Clinic

Completed

Effects of Androgen Administration on Inflammation in Normal Women

Hyperandrogenism

United States
Yale University
The John B. Pierce Laboratory

Withdrawn

Mechanisms of Blood Pressure Dysfunction in Transmen Receiving Testosterone

Hyperandrogenism | Blood Pressure | Transgender Men
Poznan University of Medical Sciences

Unknown

The Effect of Ibuprofen on Women With PCOS.

Inflammation | Hyperandrogenism | PCOS

Poland
Massachusetts General Hospital

Terminated

Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)

Kallmann Syndrome | Hypogonadotropic Hypogonadism

United States
Novartis Pharmaceuticals

Not yet recruiting

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (ASC4INDIA)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Novartis Pharmaceuticals

Active, not recruiting

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

United States, China, Hungary, Japan, Belgium, Germany, Canada, Singapore, Australia, Israel, Netherlands, Spain, Italy, Korea, Republic of, Bulgaria, France, United Kingdom, Czechia, Sweden, India, Malaysia, Denmark, Taiwan, Norway, Fi... and more
National Cancer Institute (NCI)

Recruiting

Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Unknown

Effect of Prophylactic TKI Therapy Post-transplants on Ph+ ALL Undergoing Allo-HSCT With MRD Positive Pre-transplants

Allogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Philadelphia Chromosome Positive Acute Lymphocytic Leukemia | Tyrosine Kinase Inhibitor

China
Linkoeping University

Completed

Bariatric Surgery, Hormones, and Quality of Life (OBLIV)

Quality of Life | Obesity | Hyperandrogenism | Hormone Disturbance
Massachusetts General Hospital

Completed

Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders

Kallmann Syndrome | Hypogonadotropic Hypogonadism | Puberty, Precocious | Puberty, Delayed | GnRH Deficiency

United States
Sequenom, Inc.

Completed

Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies (CHARMM-AP)

Down Syndrome | Aneuploidy

United States
University Hospital, Montpellier

Withdrawn

HIV Prevention During Chemsex (Chemsex)

Men Having Sex With Other Men
Hunter College of City University of New York
National Institute on Drug Abuse (NIDA)

Completed

Couples Health Project: Couples-based Intervention to Reduce Drug Use and HIV Transmission Risk (CHP)

Risk Behavior | Drug Use | Sex, Anal

United States
Gulhane School of Medicine

Completed

Sex Hormones and Pericardial Adipose Tissue

Pericardial Adipose Tissue and Sex Hormones
National University Hospital, Singapore

Active, not recruiting

Does an Educational Video for Aneuploidy Screening Improve Informed Choice Among Pregnant Women? (EVA)

Down Syndrome | Aneuploidy | Pregnancy Early

Singapore
Bayer

Completed

A Study to Learn How the Study Drug Elinzanetant (BAY 3427080) Affects the Way the Drug Dabigatran Moves Into, Through and Out of the Body in Healthy Male and Female Participants

Hot Flashes | Healthy Volunteers | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Germany
dr. Laura C. G. de Graaff-Herder

Recruiting

GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)

Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions

Netherlands
Boston Children's Hospital

Completed

Use of an External Erectile Device in Transgender Man Following Phalloplasty (ProstHEsis)

Erectile Dysfunction | Surgery | Transsexualism | Sex Behavior

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Minimal Residual Disease | Adult Acute Lymphoblastic Leukemia in Complete Remission

United States
Women and Infants Hospital of Rhode Island
PerkinElmer, Inc.

Completed

VAlidation of a Lower Cost aneUploidy scrEen (VALUE)

Down Syndrome | Trisomy 18 | Trisomy 13

United States, Canada, Italy
Clinique Ovo

Terminated

Detecting Early Onset Pre-eclampsia and Use of Placental Growth Factor (PlGF) for Marker of Trisomy 21 (PlGF)

Pregnancy

Canada
Children's Healthcare of Atlanta

Completed

Pulmonary Hypertension in Trisomy 21 Patients

Congenital Disorders

United States
Memorial Sloan Kettering Cancer Center
Novartis Pharmaceuticals; Incyte Corporation

Active, not recruiting

Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or Older

Acute Lymphoblastic Leukemia

United States
University of Utah
Janssen, LP

Withdrawn

Study of Pts With Philadelphia Chromosome-Pos ALL With Comb of Ibrutinib, Dasatinib, and Prednisone

Acute Lymphoblastic Leukemia

United States
Novartis Pharmaceuticals

Completed

Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase ('MACS1252)

CML in Chronic Phase

Germany, Italy, Spain, Belgium, Croatia, Hungary, Netherlands, Austria, France, Greece, Sweden, Switzerland, Bulgaria, Romania, Slovenia, United Kingdom, Lithuania, Slovakia, Denmark, Finland, Norway, Poland, Czech Republic, Portugal, E... and more
Stephanie B. Seminara, MD

Recruiting

The Molecular Basis of Inherited Reproductive Disorders

Kallmann Syndrome | Hypogonadotropic Hypogonadism | Delayed Puberty | Reproductive Disorder

United States
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Singapore, France, Germany, United Arab Emirates, Greece, Italy, Czechia, Hungary, United States, India, Oman, Malaysia, Korea, Republic of, Turkey, Bulgaria, Canada, Slovakia, United Kingdom, Argentina, Jordan, Romania, South Africa and more
National Cancer Institute (NCI)
NRG Oncology

Completed

Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary

Malignant Ovarian Epithelial Tumor | Ovarian Gynandroblastoma | Ovarian Sertoli-Leydig Cell Tumor | Ovarian Sex Cord Tumor With Annular Tubules | Ovarian Steroid Cell Tumor | Ovarian Granulosa Cell Tumor | Ovarian Sex Cord-Stromal Tumor | Ovarian Sex Cord-Stromal Tumor of Mixed or Unclassified Cell...

United States
Centre Leon Berard

Active, not recruiting

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase (TIPI)

Philadelphia Chromosome Positive CML | BCR-ABL Positive Chronic Myelogenous Leukemia

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Kinase Inhibitor

Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia

United States
Sequenom, Inc.

Recruiting

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

Down Syndrome | Fetal Aneuploidy

United States, Canada
Rennes University Hospital
Novartis; Ministry of Health, France

Completed

Safety and Efficacy of Imatinib Added to Chemotherapy in Treatment of Ph+ Acute Lymphoblastic Leukemia in Children (ESPHALL)

Acute Lymphoblastic Leukemia | Philadelphia Chromosome

France
Sequenom, Inc.

Completed

Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies

Down Syndrome | Fetal Aneuploidy

United States, Canada
Boston University Charles River Campus
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Syracuse University and other collaborators

Recruiting

Alcohol and "Heat of the Moment" Sexual Decision Making

Alcohol Drinking | Hiv | Sex, Unsafe

United States
University of Waterloo

Completed

Comparing the Effects of Different Types of Exercise on Glucose Handling

Insulin Sensitivity | Sex Differences | Glycemic Control

Canada
Dow University of Health Sciences

Unknown

Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism (mprmih)

Hyperandrogenism | Menstrual Irregularities

Pakistan
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Post-Frontline Sequential Treatment of Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

Italy

Clinical Trials on Sex Chromosome Disorders

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Jordan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations