Clinical Trials on Sleep Disordered Breathing in South Africa

Total 5867 results

American Regent, Inc.

Completed

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

Restless Legs Syndrome (RLS)

United States
Sanofi

Completed

A Study of SR58611A in the Prevention of Depression Relapse in Patients With Major Depressive Disorder (CALYPSO)

Depressive Disorder | Major Depression

France, Poland, Romania, Russian Federation, Bulgaria, Serbia, Slovakia, Czech Republic, Mexico, Argentina, Croatia, Finland, South Africa
BRC Operations Pty. Ltd.

Unknown

International Study to Predict Optimised Treatment - in Depression (iSPOT-D)

Major Depressive Disorder

United States, Australia, Netherlands, New Zealand, South Africa
Sanofi

Completed

Single and Repeated Dosing Study to Assess the Safety and the Concentration-time Profile of SAR228810 in Alzheimer's Patients

Alzheimer's Disease

Sweden, Bulgaria, France, Netherlands, South Africa
American Regent, Inc.

Terminated

Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia

Restless Legs Syndrome (RLS)

United States
Novartis Pharmaceuticals

Terminated

Effect of AQW051 in Patients With Memory Impairment

Amnestic Mild Cognitive Impairment | Mild Alzheimer's Disease

Canada, United Kingdom, South Africa
Axsome Therapeutics, Inc.

Completed

A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy (SYMPHONY)

Narcolepsy | Cataplexy | Excessive Daytime Sleepiness

United States, Canada
Incyte Corporation

Recruiting

The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance. (MORPHEUS)

Atopic Dermatitis

United States
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

An Open-Label Study to Assess the Effect of CYP3A4 Induction on the Pharmacokinetics of VELCADE (Bortezomib)

Multiple Myeloma | Non-Hodgkin's Lymphoma

Israel, Italy, Poland, South Africa, United Kingdom
Eli Lilly and Company

Completed

Lispro Mid Mixture (MM) Intensive Mixture Therapy With Progressive Dose-Titration of Lispro Low Mixture (LM) or Biphasic Insulin Aspart 30/70 (S019) (S019)

Diabetes Mellitus, Type 2

Croatia, Poland, Romania, South Africa, Turkey
Newron Pharmaceuticals SPA

Completed

Safinamide in Levodopa Induced Dyskinesia in Parkinson's Disease Subjects (Safinamide-LID)

Parkinson's Disease

Austria, Canada, France, Germany, South Africa
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance

Restless Legs Syndrome

United States
GlaxoSmithKline

Completed

A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS)

Restless Legs Syndrome

United States
Cosmetique Active International

Recruiting

Effect of Lipikar Baume AP+M on Quality of Life and Pain of Adults With Dryness or Severe Xerosis

Skin Diseases | Atopic Dermatitis

Croatia, Germany, Portugal, South Africa, Taiwan, Thailand, Vietnam
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University of Sussex; Ministry... and other collaborators

Completed

Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial (PRACTECAL-PRO)

Multidrug Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
Wake Forest University Health Sciences
Boston Scientific Corporation

Recruiting

Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy (SASS)

Stress Urinary Incontinence | Pelvic Floor Disorders

United States, South Africa
Impax Laboratories, LLC

Completed

Safety and Efficacy Study of IPX159 in Restless Legs Syndrome (RLS)

Restless Legs Syndrome

United States
Canadian Cancer Trials Group
Queen's University, Belfast; Survivorship Research Group

Active, not recruiting

Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer (CHALLENGE)

Depression | Fatigue | Colorectal Cancer | Sleep Disorders | Cognitive/Functional Effects | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment | Excercise

Canada, United States, Australia, France, Korea, Republic of, United Kingdom
Boehringer Ingelheim

Completed

A 6 Week Trial to Study the Efficacy and Safety of a Starting Dose 0.25 mg Pramipexole (Mirapex) in Patients With RLS

Restless Legs Syndrome

United States
GlaxoSmithKline

Completed

Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)

Restless Legs Syndrome | Restless Legs Syndrome (RLS)

United States
Boehringer Ingelheim

Completed

Efficacy and Safety of Pramipexole Compared to Placebo in the Treatment of Restless Legs Syndrome (RLS)

Restless Legs Syndrome

United States
XenoPort, Inc.

Completed

Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study (CONCORD)

Restless Legs Syndrome

United States
Takeda

Terminated

A Study of TAK-994 in Adults With Narcolepsy

Narcolepsy Type 1 (NT 1)

United States, Italy, Finland, Canada, Hungary, Czechia, France, Japan, Korea, Republic of, Spain
Foundation for the National Institutes of Health
Johns Hopkins University; Aga Khan University; Penn State University; University... and other collaborators

Unknown

Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED)

Immune Response | Diarrhea | Malnutrition | Wasting | Stunting | Cognitive Development

India, Pakistan, Bangladesh, Brazil, Nepal, Peru, South Africa, Tanzania
Abbott Products
Quintiles, Inc.

Completed

A Safety PK/PD Study of SLV337 in Patients With Type 2 Diabetes

Type 2 Diabetes

Bulgaria, Poland, South Africa
Arrowhead Pharmaceuticals

Active, not recruiting

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH) (Gateway)

Homozygous Familial Hypercholesterolemia

Australia, Canada, United States, South Africa
Pfizer

Completed

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder

Hypercholesterolemia, Familial

Canada, United States, South Africa
Minster Research Ltd

Completed

Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache

Migraine Without Aura | Migraine With Aura

United Kingdom, Denmark, Hungary, South Africa
Baylor College of Medicine
University of California, San Diego; University of Alabama at Birmingham; Boston... and other collaborators

Completed

Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW (RDCRN)

Prader-Willi Syndrome | Rett Syndrome | Angelman Syndrome | Sleep Problems

United States
Harmony Biosciences, LLC

No longer available

Expanded Access Program to Provide Treatment With Pitolisant to Adult Patients in the U.S. With Excessive Daytime Sleepiness Associated With Narcolepsy With or Without Cataplexy

Narcolepsy Without Cataplexy | Narcolepsy With Cataplexy

United States
Jazz Pharmaceuticals

Completed

A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

Parkinson Disease | Excessive Sleepiness

United States
Takeda

Terminated

A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

Narcolepsy Type 1 (NT1) | Narcolepsy Type 2 (NT2)

China, United States, Korea, Republic of, France, Italy, Finland, Spain, Czechia, Canada, Japan, Hungary, Netherlands
GlaxoSmithKline

Completed

Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome

Restless Legs Syndrome

United States, Canada
Laboratoire français de Fractionnement et de Biotechnologies
LFB USA, Inc.

Completed

A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa (PERSEPT2)

Hemophilia A With Inhibitors | Hemophilia B With Inhibitors

Bulgaria, Ukraine, Czechia, United States, Georgia, South Africa
GlaxoSmithKline

Completed

Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome

Restless Legs Syndrome

United States, Canada
Evgenia E. Psarraki

Completed

Efficacy of Pythagorean Self-Awareness Intervention for Major Depressive Disorder

Major Depressive Disorder

Greece
NSABP Foundation Inc
National Cancer Institute (NCI)

Unknown

Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32

Depression | Breast Cancer | Fatigue | Sleep Disorders

United States, Canada
Senesco Technologies, Inc.

Unknown

Safety and Tolerability Study of SNS01-T in Relapsed or Refractory B Cell Malignancies (Multiple Myeloma, B Cell Lymphoma, or Plasma Cell Leukemia (PCL)

Multiple Myeloma | Plasma Cell Leukemia | Multiple Myeloma in Relapse | Mantle Cell Lymphoma in Relapse | Diffuse Large B Cell Lymphoma in Relapse | Other B Cell Lymphoma in Relapse

United States, South Africa
GlaxoSmithKline

Completed

12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome ((CR-RLS))

Restless Legs Syndrome | Restless Legs Syndrome (RLS)

United States
GlaxoSmithKline

Completed

A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome

Restless Legs Syndrome | Restless Legs Syndrome (RLS)

United States
Novo Nordisk A/S

Completed

A Survey on Low Blod Sugar Among Insulin-treated Patients With Diabetes

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Turkey, Egypt, Philippines, United Arab Emirates, Bangladesh, Colombia, Singapore, South Africa
Pfizer

Completed

PF-06741086 Multiple Dose Study in Severe Hemophilia

Hemophilia A or B

United States, Chile, Croatia, Poland, South Africa, Switzerland
Laboratoire français de Fractionnement et de Biotechnologies
LFB USA, Inc.

Completed

LR769 in Congenital Hemophilia Patients With Inhibitors Undergoing Elective Surgery or Invasive Procedures (PerSept3)

Hemophilia

United States, Ukraine, Mexico, Russian Federation, South Africa, Spain
Ioannis A. Malogiannis
National and Kapodistrian University of Athens; Attikon Hospital; University... and other collaborators

Recruiting

Specialized Healthcare Service for BPD Patients: Athens Trial (BPDAS)

Other Mental Conditions

Greece
Boehringer Ingelheim

Completed

Sifrol (Pramipexole) Onset of Action and Impact: a 12-weeks Observational Study in Patients With Primary Restless Legs Syndrome

Restless Legs Syndrome

Austria
Eli Lilly and Company

Completed

Safety, Tolerability, and Effect of LY2405319 After Multiple Injections in Subjects With Type 2 Diabetes

Type 2 Diabetes

India, Mexico, New Zealand, South Africa
GlaxoSmithKline

Completed

A Study of the Pharmacokinetics of Albiglutide in Normal and Renally Impaired Subjects.

Diabetes Mellitus, Type 2

United States, South Africa
Bayer

Completed

REPEAT - Real-Life Perception of Efficacy, Attitude, Satisfaction and Safety of Levitra Therapy

Erectile Dysfunction

Poland, China, Croatia, France, Germany, Hungary, Indonesia, Korea, Republic of, Malaysia, Saudi Arabia, Singapore, South Africa, Spain, Sweden, Thailand
Novo Nordisk A/S

Completed

Safety of Insulin Detemir Produced by a New Process as Measured by Antibody Formation in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Germany, South Africa, Russian Federation, Former Serbia and Montenegro, North Macedonia
Sanofi

Completed

Evaluation of the Blood Levels of the Drug (Lixisenatide), the Plasma Glucose Levels and Safety in Paediatric and Adult Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Mexico, United Kingdom

Clinical Trials on Sleep Disordered Breathing in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Mali

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Rare Diseases

Drug Interventions

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