Clinical Trials on Spinal Cord Disease in Belgium

Total 11229 results

Universitaire Ziekenhuizen KU Leuven

Enrolling by invitation

3D, Dynamic and Mechanically-informed Decision Making in AIS (3D-AIS)

Adolescent Idiopathic Scoliosis

Belgium
Novartis Pharmaceuticals

Recruiting

Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials (SPECTRUM)

Spinal Muscular Atrophy (SMA)

Spain, Canada, Taiwan, Belgium, Malaysia, China, Japan, Italy, Singapore, United Kingdom, France, Australia, Thailand, Denmark, United States
Hoffmann-La Roche

Completed

Investigate Safety, Tolerability, PK, PD and Efficacy of Risdiplam (RO7034067) in Infants With Type1 Spinal Muscular Atrophy (FIREFISH)

Muscular Atrophy, Spinal

Belgium, United States, China, Spain, Japan, France, Brazil, Croatia, Italy, Russian Federation, Saudi Arabia, Serbia, Switzerland, Turkey, Ukraine, Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants (SUNFISH)

Muscular Atrophy, Spinal

Belgium, United States, China, Spain, Japan, Canada, France, Poland, Brazil, Croatia, Italy, Russian Federation, Turkey, Germany, Serbia, United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) (SMART)

Spinal Muscular Atrophy

Taiwan, Belgium, Canada, United States, Australia, France, Italy, Portugal, United Kingdom
Biogen

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB115

Healthy Volunteer | Muscular Atrophy, Spinal

Korea, Republic of, Germany, Belgium, Netherlands, France, Italy, Poland, Canada, United Kingdom, Israel
Biogen

Terminated

A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (ENDEAR)

Spinal Muscular Atrophy

Korea, Republic of, United States, Spain, Canada, Germany, Australia, Japan, Sweden, Belgium, France, Italy, Turkey, United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam (STRENGTH)

Spinal Muscular Atrophy

Japan, Belgium, Spain, Canada, United States, Australia, Italy, France, Netherlands
University Hospital, Antwerp

Completed

Multidisciplinary Perioperative Care Pathway in Adolescents Undergoing Posterior Spinal Fusion Surgery

Postoperative Pain | Analgesia | Surgery | Scoliosis Idiopathic

Belgium
AZ Sint-Jan AV

Active, not recruiting

Cardiac Amyloidosis in Spinal Stenosis: the CASS-study (CASS)

Cardiac Amyloidosis

Belgium
Biogen

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE)

Spinal Muscular Atrophy

United States, Spain, Germany, United Kingdom, Australia, Japan, Canada, Belgium, France, Hong Kong, Italy, Korea, Republic of, Sweden, Turkey
Cliniques universitaires Saint-Luc- Université...

Active, not recruiting

Early UVFP Management Based on Neurological Evidences (UVFP = Unilateral Vocal Fold Paralysis) (IONS-UVFP)

Unilateral Vocal Cord Paralysis

Belgium
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy (RESILIENT)

Neuromuscular Diseases | Spinal Muscular Atrophy | SMA

United States, Netherlands, United Kingdom, Spain, Czechia, Belgium, Germany, Italy, Poland
Novartis Gene Therapies

Active, not recruiting

Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi

SMA | Spinal Muscular Atrophy Type II | Spinal Muscular Atrophy Type I | Spinal Muscular Atrophy Type III

United States, Belgium, France, Japan, United Kingdom, Italy, Taiwan, Australia, Canada
Ipsen

Terminated

Dysport® Treatment of Urinary Incontinence in Adults Subjects With Neurogenic Detrusor Overactivity (NDO) Due to Spinal Cord Injury or Multiple Sclerosis - Study 2 (CONTENT2)

Overactive Bladder | Urinary Incontinence

Spain, Israel, Russian Federation, France, Germany, Australia, Belgium, Brazil, United Kingdom, Mexico, Colombia, Chile, Argentina, Lithuania, Peru, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

Clinical Pharmacology Study to Evaluate the Total Systemic Exposure and the Lung Availability of CHF 5993 in Healthy Volunteers

COPD

Belgium
University Hospital, Ghent

Completed

Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS). (NIRS continu)

Nfuence of Vasoactive Medication on Spinal Oxygenation

Belgium
Erasme University Hospital

Recruiting

Effects of Endoscopic Lung Volume Reduction on Diaphragm Function and Conformation

COPD

Belgium
Cliniques universitaires Saint-Luc- Université...

Completed

Music and Perceived Rate of Exertion

COPD

Belgium
RTI Surgical

Completed

Comparison of nanOss Cervical IBF System to C-Plus PEEK IBF Device With Autograft

Intervertebral Disc Degeneration

Belgium
Teva Pharmaceutical Industries, Ltd.

Completed

Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Israel, Italy, United Kingdom
KU Leuven

Completed

Effects of Physical Activity Counseling After an Exacerbation in COPD

COPD Exacerbation

Belgium
ApoPharma

Completed

A Study Investigating the Long-term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Belgium, France, Italy, Spain
Chiesi Farmaceutici S.p.A.

Completed

Drug-drug Interaction Study of CHF5993 With Cimetidine

COPD

Belgium
Pearl Therapeutics, Inc.

Completed

A Study to Assess the Effects of PT003 and Placebo MDI on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD

COPD

Belgium
QurAlis Corporation

Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis

Canada, Germany, Netherlands, Ireland, United Kingdom, Belgium
KU Leuven
University Ghent

Completed

Long-term Activity Coaching in Patients With COPD

COPD

Belgium
University Hospital, Antwerp

Completed

Prospective Exploratory Study to Assess the Effects of the AlphaCore® Device in Patients With COPD

COPD

Belgium
Medacta International SA

Completed

Cortical Bone Trajectory With Patient Guide (MySpine MC)

Degenerative Disc Disease

Belgium
Stichting TRICALS Foundation
Research Foundation Flanders; Stichting ALS Nederland; Fight MND; MNDA; Thierry Latran... and other collaborators

Recruiting

Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Belgium, Netherlands, United Kingdom, Sweden, Spain, Australia
Scholar Rock, Inc.

Active, not recruiting

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX (ONYX)

Neuromuscular Diseases | Neuromuscular Manifestations | Atrophy | Muscular Atrophy | Spinal Muscular Atrophy | Muscular Atrophy, Spinal | Spinal Muscular Atrophy Type 3 | SMA | Anti-myostatin | Spinal Muscular Atrophy Type II

United States, Spain, Belgium, Germany, Netherlands, Poland, Italy, France, United Kingdom
Minoryx Therapeutics, S.L.

Completed

A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients (FRAMES)

Friedreich Ataxia

Spain, Belgium, France, Germany
University Ghent
University Hospital, Ghent; Agentschap voor Innovatie door Wetenschap en Technologie and other collaborators

Completed

Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training

Chronic Spinal Pain

Belgium
Centre Hospitalier Universitaire Saint Pierre
Hôpital de Braine-l'Alleud

Completed

Comparison of Hyperbaric Prilocaine With Chloroprocaine for Intrathecal Anaesthesia in Day Case Knee Arthroscopy

Spinal Anesthesia | Knee Arthroscopy

Belgium
KU Leuven

Recruiting

Enhancing Muscle Function After Exacerbations of COPD to Limit Its Impact on Physical Activity Decline

COPD Exacerbation

Belgium
Hoffmann-La Roche

Completed

Safety Extension Study of TRO19622 in ALS

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
Scholar Rock, Inc.

Active, not recruiting

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam (SAPPHIRE)

Neuromuscular Diseases | Neuromuscular Manifestations | Atrophy | Muscular Atrophy | Spinal Muscular Atrophy | Muscular Atrophy, Spinal | Spinal Muscular Atrophy Type 3 | SMA | Spinal Muscular Atrophy Type 2 | Anti-myostatin

United States, Germany, Belgium, Spain, United Kingdom, Netherlands, France, Italy, Poland
University Hospital, Ghent

Completed

Influence of a Bolus Administration of Ephedrine and Phenylephrine on the Spinal Oxygen Saturation, Measured With NIRS. (NIRS BOLUS)

Influence of Vasoactive Medication on Spinal Oxygenation

Belgium
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Recruiting

Open Label Extension of TUDCA-ALS Study (TUDCA-ALS OLE)

Amyotrophic Lateral Sclerosis

Germany, France, Netherlands, Italy, United Kingdom, Belgium, Ireland
Brugmann University Hospital

Recruiting

Post Spinal Anesthesia Hypotension and Preoperative Hydration

Cesarean Section | Anesthesia, Spinal

Belgium
Universitaire Ziekenhuizen KU Leuven
University College, London; Wellcome Trust

Unknown

Fetal Surgery Interview Study: Parental Perceptions of Fetal Surgery

Congenital Diaphragmatic Hernia | Myelomeningocele | Fetal Surgery

Belgium, United Kingdom
Hoffmann-La Roche
European Commission

Completed

Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS (MITOTARGET)

Amyotrophic Lateral Sclerosis

Belgium, France, Germany, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

United States, Belgium, Canada, France, Germany, Italy, Netherlands, Switzerland, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers (TRIPLE 1)

COPD

Belgium
AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
Hasselt University

Unknown

Changes in Microcirculation and Functional Status During Exacerbation of COPD (COPD-EX)

Physical Activity | COPD Exacerbation | Retinal Vascular

Belgium
Centre Hospitalier Universitaire Saint Pierre

Completed

Has Pulmonary Rehabilitation a Positive Impact on Sleep Quality in Patients Suffering From COPD ?

COPD

Belgium
ApoPharma

Completed

A Study Investigating the Safety and Tolerability of Deferiprone in Patients With Friedreich's Ataxia

Friedreich's Ataxia

Canada, Australia, Belgium, France, Italy, Spain
University Hospital, Antwerp
GlaxoSmithKline

Completed

Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients

COPD

Belgium
KU Leuven

Completed

Exacerbation and Training in Patients With Chronic Obstructive Pulmonary Disease (EXTRA)

COPD

Belgium

Clinical Trials on Spinal Cord Disease in Belgium

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Portugal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations