Clinical Trials on Symptoms

Total 242695 results

Shirley Ryan AbilityLab

Recruiting

Nomad P-KAFO Study

Multiple Sclerosis | Paralysis | Muscular Dystrophy | Spinal Cord Injuries | Cerebrovascular Accident | Post-polio Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases (MuTreg)

Multiple Sclerosis | Autoimmune Diseases | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Atopic Dermatitis | Vitiligo | Alopecia | Autoimmune Thyroiditis | Inflammatory Disease | Acquired Bone Marrow Aplasia | Gvhd
University of Aarhus
Aarhus University Hospital

Recruiting

Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype (EMKISCA)

Cardiovascular Diseases | Turner Syndrome | Metabolic Disease | Klinefelter Syndrome | Immunologic Disease | Sex Chromosome Abnormality

Denmark
Pharvaris Netherlands B.V.

Recruiting

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-2)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
Shanghai Jiao Tong University School of Medicine

Recruiting

Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.

Asthma | Emphysema | Allergic Rhinitis | Eczema | Atopic Dermatitis | Bronchitis | Chronic Obstructive Pulmonary Disease(COPD) | Urticaria | Bronchiectasis Adult

China
Genelux Corporation
GOG Foundation

Recruiting

Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

Fallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Platinum-refractory Ovarian Cancer | Primary Peritoneal Cancer | High-grade Serous Ovarian Cancer | Endometrioid Ovarian Cancer | Ovarian Clear Cell Carcinoma

United States
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
M.D. Anderson Cancer Center

Recruiting

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

Endometrial Clear Cell Adenocarcinoma | Endometrial Dedifferentiated Carcinoma | Endometrial Serous Adenocarcinoma | Malignant Uterine Neoplasm | Endometrial Mucinous Adenocarcinoma | Uterine Corpus Carcinosarcoma

United States
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Recruiting

Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years

Vaginal Cancer | Cervical Cancer Stage IIa | CIN1 | CIN2 | CIN3 | Genital Wart | HPV Infections

China
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Recruiting

Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | VIN 1 | VIN 2 | VIN 3 | AIS | HPV Infections | CIN 3

China
University Hospital, Strasbourg, France

Recruiting

Cerebro Spinal Fluid Collection (CSF) (Analzheimer)

Alzheimer Disease | Multiple System Atrophy | Frontotemporal Dementia | Dementia With Lewy Bodies | Parkinson's Disease Dementia

France
University of Cagliari
Chiara Gerardi - Istituto Di Ricerche Farmacologiche Mario Negri; Federico... and other collaborators

Recruiting

coMpliAnce With evideNce-based cliniCal Guidelines in the managemenT of Acute biliaRy pancreAtitis (MANCTRA-1)

Covid19 | Acute Pancreatitis | Acute Pancreatic Necrosis | Acute Pancreatic Fluid Collection | Acute Pancreatitis Without Necrosis or Infection | Acute Pancreatitis Due to Gallstones | Acute Pancreatitis With Infected Necrosis | Acute Pancreatitis Due to Common Bile Duct Calculus | Acute Pancreatitis... and other conditions

Italy, Spain
Royal Marsden NHS Foundation Trust

Recruiting

Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies (PREVAILctDNA)

Biliary Tract Neoplasms | Neoplasm, Bladder | Neoplasm of Lung | Neoplasms Pancreatic | Neoplasm, Colorectal | Gastro Intestinal Stromal Tumour

United Kingdom
Ditte Hansen
Odense University Hospital; Rigshospitalet, Denmark; Steno Diabetes Center Copenhagen and other collaborators

Recruiting

Treatment of Adynamic Bone Disorder With Parathyroid Hormone in Chronic Kidney Disease

Chronic Kidney Diseases | Cardiac Disease | Chronic Kidney Disease-Mineral and Bone Disorder | Adynamic Bone Disease

Denmark
University Hospital Tuebingen

Recruiting

Randomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Radiotherapy (OnkoFit II)

Sarcoma | Head and Neck Cancer | Pancreas Cancer | Esophageal Carcinoma | Cervix Uteri Cancer | Bronchial Carcinoma | Tumor of the Brain

Germany
American Thrombosis and Hemostasis Network
Sanofi; Pfizer; Genentech, Inc.; CSL Behring; Hemophilia of Georgia, Inc.; Hemab Therapeutics

Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

Hemophilia | Thrombosis | Thrombophilia | Sickle Cell Disease | Thalassemia | Bleeding Disorder | Von Willebrand Diseases | Factor IX Deficiency | Connective Tissue Disorder | Factor VIII Deficiency | Hematologic Disorder | Rare Bleeding Disorder | Platelet Disorder

United States
National Cancer Institute (NCI)

Recruiting

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Colorectal Neoplasms | Advanced Breast Cancer | Advanced Solid Tumors | Malignant Peripheral Nerve Sheath Tumor | Metastatic Pancreatic Cancer | Pediatric Solid Tumor

United States
Seattle Children's Hospital

Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Glioma | Ependymoma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Central Nervous System Tumor | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Pineoblastoma, Childhood

United States
Klinikum Oldenburg gGmbH
Deutsche Gesellschaft für Kinderendokrinologie und Diabetologie (DGKED); Deutsche... and other collaborators

Recruiting

Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts

Obesity | Craniopharyngioma

Germany
General Oncology, Inc.
Myriad Genetics, Inc.

Recruiting

SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation | Pancreatic Acinar Cell Carcinoma | Metastatic Pancreatic Cancer | Breast Cancer Metastatic | HER2-negative Breast Cancer | Metastatic Pancreatic Ductal Adenocarcinoma and other conditions

United States
ProgenaBiome

Recruiting

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease

Alzheimer Disease | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Alzheimer Disease 1 | Alzheimer Disease 2 | Alzheimer Disease 3 | Alzheimer Disease 4 | Alzheimer Disease 7 | Alzheimer Disease 17 | Alzheimer Disease 5 | Alzheimer Disease 6 | Alzheimer Disease 8 | Alzheimer Disease 10 | Alzheimer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

Acute Myeloid Leukemia | High Risk Myelodysplastic Syndrome | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | Myeloproliferative Neoplasm | Myeloid Sarcoma | Blasts 10 Percent or More of Bone Marrow Nucleated Cells

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recurrent Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Refractory Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Lymphoma | Clonal Cytopenia of Undetermined Significance | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements

United States
Wuerzburg University Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); St George... and other collaborators

Recruiting

Evaluation of HEArt invoLvement in Patients With FABRY Disease (HEAL-FABRY)

Fabry Disease | Rare Diseases | Hypertrophic Cardiomyopathy | Fabry Disease, Cardiac Variant

Germany
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL) (MABEL)

Nasopharyngeal Carcinoma | Hodgkin Disease | Non-Hodgkin Lymphoma | Severe Chronic Active Epstein Barr Virus | T/NK-lymphoproliferative Disease | Smooth Muscle Tumor

United States
Children's Hospital Medical Center, Cincinnati
Memorial Sloan Kettering Cancer Center; Fred Hutchinson Cancer Center

Recruiting

HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Severe Marrow Failure

United States
National Cancer Institute (NCI)

Recruiting

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

Kidney Cancer | Renal Cell Carcinoma | Urologic Malignant Disorders | Familial Renal Cancer (FRC) | Clear Cell Renal Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Lynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States, Canada, Puerto Rico, Peru, South Africa
National Cancer Institute (NCI)

Active, not recruiting

Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma

Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Recurrent Nasopharyngeal Undifferentiated Carcinoma | Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 | Adult Nasal Type Extranodal NK/T-Cell Lymphoma | Stage IV Nasopharyngeal Undifferentiated Carcinoma...

United States, Singapore, Japan, Hong Kong
Ohio State University Comprehensive Cancer Center
Merck Sharp & Dohme LLC

Active, not recruiting

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Sezary Syndrome | Chronic Lymphocytic Leukemia | Peripheral T-Cell Lymphoma | Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | T-Cell Prolymphocytic Leukemia | B-Cell Prolymphocytic Leukemia

United States
Massachusetts Eye and Ear Infirmary
National Eye Institute (NEI)

Active, not recruiting

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

Stroke | Myasthenia Gravis | Traumatic Brain Injury | Chronic Progressive External Ophthalmoplegia | Ptosis, Eyelid | Blepharoptosis

United States
April M Young
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Sexually Transmitted Diseases | Opioid-Related Disorders | Substance Abuse | Drug Overdose | Opiate Substitution Treatment | Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV) | Intravenous Drug Usage

United States
Saint Petersburg State University, Russia

Completed

Impact of Parathyroidectomy on Cardiovascular Calcification in Dialysis-dependent Patients

Secondary Hyperparathyroidism | Dialysis | Vascular Calcification | Chronic Kidney Disease Mineral and Bone Disorder

Russian Federation
Regeneron Pharmaceuticals

Suspended

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Non-Small Cell Lung Cancer | Triple Negative Breast Cancer | Merkel Cell Carcinoma | Basal Cell Carcinoma | Oropharynx Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States, Australia
AbbVie

Available

Expanded Access to Venetoclax

Multiple Myeloma | Non-Hodgkin's Lymphoma | Amyloidosis | Chronic Lymphocytic Leukemia (CLL) | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Plasma Cell Leukemia
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma

Advanced Merkel Cell Carcinoma | Metastatic Merkel Cell Carcinoma | Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8 | Pathologic Stage IIIA Cutaneous Merkel... and other conditions

United States
TCR2 Therapeutics
Bristol-Myers Squibb

Active, not recruiting

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Cholangiocarcinoma | Non Small Cell Lung Cancer Metastatic | Mesotheliomas Pleural | Mesothelioma Peritoneum | Mesothelioma; Pleura | Cholangiocarcinoma Recurrent | High Grade Ovarian Serous Adenocarcinoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)

Metastatic Gastrointestinal Stromal Tumor | Metastatic Sarcoma | Locally Advanced Sarcoma | Locally Advanced Gastrointestinal Stromal Tumor | Stage III Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8 | Stage III Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal... and other conditions

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Alrijne Hospital

Completed

Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis (STONE)

Kidney Diseases | Urologic Diseases | Kidney Calculi | Urinary Calculi | Urolithiasis | Stone Ureter | Stone, Kidney | Urinary Stone | Pyelonephritis | Hydronephrosis | Obstruction | Kidney Failure, Acute | Ureter Obstruction | Urinary Obstruction | Kidney Dysfunction | Kidney Insufficiency | Pyelonephritis Acute | Stone, Urinary and other conditions

Netherlands
Hospital del Mar Research Institute (IMIM)

Enrolling by invitation

The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers (PLASMAR)

Neurodegenerative Diseases | Cognitive Impairment | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

Spain
Azafaros A.G.

Active, not recruiting

Phase 2 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZ-3102 in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease (RAINBOW)

Niemann-Pick Disease, Type C | GM2 Gangliosidosis

Brazil
THERAPIM PTY LTD
Novotech (Australia) Pty Limited

Terminated

A Study to Evaluate the Combination of ATX-101 and Platinum-based Chemotherapy

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | High Grade Serious or Endometrioid Carcinoma of the Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Australia
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer

HLRCC | Sporadic Papillary Renal Cell Cancer

United States
CanariaBio Inc.
Veristat, LLC

Active, not recruiting

A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.

Peritoneal Cancer | Recurrent Ovarian Cancer | Recurrent Fallopian Tube Cancer | Recurrent Epithelial Cancer of Ovary | Recurrent Epithelial Ovarian Cancer | Recurrent Carcinoma of Ovary | Adenocarcinoma of Ovary

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Richter Syndrome | Indolent Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Malignant Glioma | WHO Grade 3 Glioma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Central Nervous System Neoplasm | Recurrent Brain Neoplasm | Recurrent Childhood...

United States
Aristotle University Of Thessaloniki

Terminated

Use of Electrical Impedance Spectroscopy (EIS) for Early Diagnosis of Skin Damage (DermaSense)

Carcinosarcoma | Melanoma (Skin) | Basal Cell Carcinoma | Squamous Cell Carcinoma | Seborrheic Keratosis | Dysplastic Nevus Syndrome | Lentigo Maligna | Lichen Planus-Like Keratosis

Greece
M.D. Anderson Cancer Center
Pfizer

Terminated

Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow

Renal Cell Carcinoma | Von Hippel-Lindau Syndrome | Hemangioblastoma

United States
University College London Hospitals

Completed

CAR T Cell Therapy Related Cardiovascular Outcomes (CARTCO)

Cardiovascular Diseases | Diffuse Large B Cell Lymphoma | Cardiotoxicity | B-cell Acute Lymphoblastic Leukemia | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | B-cell Lymphoma Refractory | Cardiovascular Complication | B-cell Lymphoma Recurrent

United Kingdom

Clinical Trials on Symptoms

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Suriname

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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