Clinical Trials on Systemic Infections/Bacteremia/Meningitis

Total 25674 results

University of Geneva, Switzerland
Centre Hospitalier Universitaire Vaudois; Cantonal Hospital of St. Gallen

Completed

Antibiotic Durations for Gram-negative Bacteremia (PIRATE)

Bacteraemia Caused by Gram-Negative Bacteria

Switzerland
Hamad Medical Corporation

Completed

Switch to Oral Antibiotics in Gram-negative Bacteremia (SOAB)

Escherichia Coli Bacteremia | Klebsiella Bacteraemia | Enterobacter Bacteraemia | Serratia Bacteraemia | Citrobacter Bacteraemia | Proteus Bacteraemia

Qatar, Turkey, Bahrain, Kuwait
MJM Bonten
Paris 12 Val de Marne University

Completed

Ecological Effects of Decolonisation Strategies in Intensive Care (RGNOSIS)

ICU-ecology (Multidrug Resistant Bacteria) | ICU-acquired Bacteraemia

Belgium, Spain, United Kingdom, Italy, Portugal, Slovenia
MeMed Diagnostics Ltd.

Completed

Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections (CURIOSITY)

Gastroenteritis | UTI | LRTI | Fever Without Source | Systemic Infections/Bacteremia/Meningitis

Israel
The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
Papua New Guinea Institute of Medical Research
The University of Western Australia

Unknown

Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children (PCV1103)

Pneumonia | Sepsis | Meningitis | Otitis Media | Bacteraemia

Papua New Guinea
Liverpool University Hospitals NHS Foundation Trust

Not yet recruiting

Process Mapping and Data Collection to Inform a Computer Simulation Model of Hospitalised Patients With Bloodstream Infection, Sepsis and Systemic Infection (CSM-BSI)

Sepsis | Bloodstream Infection | Bacteraemia
Walvax Biotechnology Co., Ltd.

Completed

A Study to Demonstrate Non-inferior Immunogenicity of Yuxi Walvax MPV ACYW® Vaccine in Healthy Subjects Aged 2-10 Years

Neisseria Meningitides Meningitis

Mali
University Hospital, Montpellier

Unknown

Evaluation of Post Infectious Inflammatory Reaction (PIIR) Concerning Children After Streptococcus Pneumoniae, Streptococcus Pyogenes and Neisseria Meningococcus Invasive Infection (RIPI)

Streptococcus Pyogenes Infection | Streptococcus Pneumonia | Neisseria Meningitides Meningitis

France
National Taiwan University Hospital
Far Eastern Memorial Hospital

Unknown

A Prospective Observational Study of Patients With Drug Resistant Acinetobacter Baumannii Bacteremia (ANTI-AB)

Acinetobacter Bacteraemia

Taiwan
National Institute of Allergy and Infectious Diseases...

Completed

DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia

Staphylococcal Bacteraemia

United States, Canada
PRo-IV
Bait Balev Hospital

Unknown

Safety and Efficacy of Immages System in Patients Recieving IV Therapy (IV)

Sepsis | CHF | Bacteriemia

Israel
Taipei Veterans General Hospital, Taiwan
Merck Sharp & Dohme LLC

Unknown

Imipenem and Sulbactam in the Treatment of Imipenem-resistant Acinetobacter Baumannii Bacteremia

Acinetobacter Bacteraemia

Taiwan
Pfizer

Completed

Safety and Immunogenicity Study of MenC-TT Vaccine (NeisVac-C) in Toddlers Previously Immunized With PCV7 (Prevenar®)

Neisseria Meningitidis (Bacterial Meningitis) | Invasive Pneumococcal Disease (IPD)

Germany
Tan Tock Seng Hospital
Melbourne Health; National University Hospital, Singapore; Samsung Medical Center and other collaborators

Recruiting

Early Oral Step-down Antibiotic Therapy for Uncomplicated Gram-negative Bacteraemia

Gram-negative Bacteraemia

Singapore
B. Braun Melsungen AG

Completed

Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)

Catheter Related Bloodstream Infection | Bacteriaemia

Czech Republic
Sanofi Pasteur, a Sanofi Company

Completed

Dose Comparison Study of Menactra® in US Children

Meningitis | Meningococcal Infection | Neisseria Meningitidis

United States
University of Zurich

Completed

PVP Iodine Effect on Post Debridement Bacteraemia (PJB 1)

Bacteraemia Post Debridement

Switzerland
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV

Gram-Negative Bacterial Infections | Bacteremia Caused by Gram-Negative Bacteria | Gram Negative Pneumonia
Charite University, Berlin, Germany

Recruiting

Early Diagnosis of Native and Device-associated Meningitis

Bacterial Meningitis | Implant Infection | Fungal Meningitis

Germany
University of Bologna

Unknown

Combination Treatment for Enterococcus Faecalis Bacteriemia Multicenter, Observational Study"

Bloodstream Infection | Enterococcal Bacteraemia | Enterococcus Faecalis Infection | Enterococcal Endocarditis

Italy
Universitaire Ziekenhuizen KU Leuven

Completed

Direct Thrombin Inhibitors Versus LMWH in Staphylococcus Aureus Bacteraemia

Staphylococcus Aureus Bacteraemia

Belgium
William Beaumont Hospitals

Terminated

Betadine Bladder Irrigations vs. Standard of Care Prior to Indwelling Catheter Removal

Urinary Tract Infections | Catheter Infection | Catheter-Related Infections | Catheter; Infection (Indwelling Catheter) | Catheter Bacteraemia

United States
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Terminated

An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures

Endocarditis | Bacteraemia

Spain
Prof. Elizabeth Miller
Novartis Vaccines

Completed

Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults (MenOccy)

Meningococcal Meningitis, Serogroup A | Meningococcal Meningitis, Serogroup B | Meningococcal Meningitis, Serogroup C | Meningococcal Meningitis, Serogroup Y | Meningococcal Meningitis, Serogroup W

United Kingdom
JESUS RODRIGUEZ BAÑO

Completed

Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to Extended-spectrum Beta-lactamase (ESBL) or Carbapenemase-producing Enterobacteriaceae: an Observational Multinational Study (INCREMENT)

Clinically Significant Bacteremia

Spain
Sohag University

Not yet recruiting

The Role of Serum Procalcitonin in Diagnosis and Detection of Outcome of Acute Bacterial Meningitis in Childern

CNS Infection in Children
National Institute of Allergy and Infectious Diseases...

Recruiting

Fungal Infection Susceptibility

Cryptococcosis | Cryptococcal Meningitis | Cryptococcal Infection | Cryptococcal Pneumonia | Pulmonary Cryptococcosis

United States
Xinhua Hospital, Shanghai Jiao Tong University...
Children's Hospital of Fudan University; Shanghai Children's Medical Center

Recruiting

Neonatal Bacterial Meningitis Cohort

Bacterial Meningitis | Neonatal Infection

China
Shaare Zedek Medical Center

Withdrawn

A New Enzymatic Assay for Rapid Diagnosing of Central Nervous System Enteroviral Infection

Viral Meningitis

Israel
American University of Beirut Medical Center
PneumoADIP

Unknown

Lebanese Interhospital Pneumococcal Surveillance Program (LIPSP)

Pneumonia | Sepsis | Bacteremia | Meningitis

Lebanon
Pfizer

Terminated

Colombia Epidemiologic Surveillance Study (LEAP II)

Pneumonia | Sepsis | Bacteremia | Meningitis

Colombia, Brazil, Costa Rica
Center for Vaccine Development - Mali
University College, London; University of Oxford; Public Health England; University... and other collaborators

Recruiting

A Human Controlled Infection Study With Neisseria Lactamica in Malian Adults

Meningitis, Meningococcal

Mali
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Parexel; BioMé...

Recruiting

Fast Antibiotic Susceptibility Testing for Gram Negative Bacteremia Trial (FAST)

Bloodstream Infection | Gram-negative Bacteremia

Israel, India, Spain, Greece
Rambam Health Care Campus

Withdrawn

Amikacin Penetration Into the Cerebrospinal Fluid

Gram Negative Meningitis | Post Traumatic Bacterial Meningitis

Israel
Sanofi Pasteur, a Sanofi Company

Completed

Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjugate Vaccine

Meningitis | Neisseria Meningitidis | Meningococcemia

United States
University of Minnesota
National Institute of Neurological Disorders and Stroke (NINDS); Medical Research... and other collaborators

Completed

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis (ASTRO-CM)

Cryptococcal Meningitis | Fungal Meningitis

Uganda
Alteco Medical AB

Withdrawn

Remove LPS Registry

Suspected or Diagnosed Endotoxemia Casued by Gram-negative Bacteria
KU Leuven
Research Foundation Flanders; National Institute for Health and Disability...

Completed

Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care (ERNIE2)

Pneumonia | Sepsis | Abscess | Cellulitis | Meningitis | Osteomyelitis | Complicated Urinary Tract Infection | Bacteraemia | Gastro-enteritis With Dehydration | Viral Respiratory Infection Complicated With Hypoxia

Belgium
ContraFect

Completed

A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)

United States
Kamuzu University of Health Sciences

Completed

Infant Severe Sepsis and Bacterial Meningitis in Malawi (Infaseme)

Infant Bacterial Meningitis

Malawi
Vanderbilt University Medical Center

Recruiting

Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes

Bloodstream Infection | Vancomycin | MRSA Bacteremia | Sepsis Bacterial

United States
Pfizer

Completed

A Trial to Assess the Safety, Tolerability and Immunogenicity of Repevax and rLP2086 Vaccine When Given Together in Healthy Subjects Aged >=11 to <19 Years.

Meningitis | Meningococcal Vaccine | rLP2086 | Repevax | N Meningitidis Serogroup B

Germany, Finland, Poland
Chiron Corporation

Unknown

Kinetic of Immune Memory Response After Re-Vaccination With Meningococcal Vaccine

Meningococcal Disease; Meningococcal Meningitis

United Kingdom
Spanish Network for Research in Infectious Diseases
European Society of Clinical Microbiology and Infectious Diseases

Completed

Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. (INCREMENT-SOT)

Pathologic Processes | Sepsis | Systemic Inflammatory Response Syndrome | Inflammation | Bacterial Infections | Bacteremia | Infection | Organ Transplantation | Clinically Significant Bacteremia

Spain
Armata Pharmaceuticals, Inc.
United States Department of Defense

Recruiting

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia (diSArm)

Bacteremia | Staphylococcus Aureus | Staphylococcus Aureus Bacteremia | Bacteremia Due to Staphylococcus Aureus | Bacteremia Staph

United States, Australia
Matinas BioPharma Nanotechnologies, Inc.
University of Minnesota

Not yet recruiting

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3 (EnACT3)

Cryptococcal Meningitis
Makerere University
Gilead Sciences; University of Minnesota

Recruiting

Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia (ACACIA)

Cryptococcal Meningitis

Uganda
Matinas BioPharma Nanotechnologies, Inc.
University of Minnesota

Completed

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) (EnACT)

Cryptococcal Meningitis

Uganda
TTY Biopharm

Unknown

Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

Taiwan

Clinical Trials on Systemic Infections/Bacteremia/Meningitis

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