Clinical Trials on Thyroid Cancer, Medullary

Total 52748 results

University Medical Center Groningen

Recruiting

Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer (MIMETIC)

Medullary Thyroid Cancer | Thyroid Cancer, Medullary | Medullary Thyroid Carcinoma | Thyroid Carcinoma, Medullary

Netherlands
Genzyme, a Sanofi Company

Completed

CAPRELSA® REGISTRY: a Belgian Registry to Evaluate the Use of Vandetanib (Caprelsa®) in Current Clinical Practice (CaprelsaReg)

Metastatic Medullary Thyroid Cancer

Belgium
University of Washington
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating Patients With Iodine-Refractory Recurrent or Metastatic Thyroid Cancer

Recurrent Thyroid Cancer | Thyroid Gland Medullary Carcinoma | Stage IVA Follicular Thyroid Cancer | Stage IVA Papillary Thyroid Cancer | Stage IVB Follicular Thyroid Cancer | Stage IVB Papillary Thyroid Cancer | Stage IVC Follicular Thyroid Cancer | Stage IVC Papillary Thyroid Cancer

United States
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid in Treating Patients With Metastatic and/or Locally Advanced or Locally Recurrent Thyroid Cancer

Insular Thyroid Cancer | Recurrent Thyroid Cancer | Stage II Follicular Thyroid Cancer | Stage II Papillary Thyroid Cancer | Stage IV Follicular Thyroid Cancer | Stage IV Papillary Thyroid Cancer | Thyroid Gland Medullary Carcinoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

European Multicenter Study on Surgical Management of Advanced Thyroid Cancer (ATCEU)

Thyroid Neoplasms | Thyroid Cancer, Papillary | Thyroid Cancer, Follicular | Thyroid Carcinoma | Thyroid Cancer | Anaplastic Thyroid Cancer | Thyroid Medullary Carcinoma

Italy
National Cancer Institute (NCI)

Completed

Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer

Recurrent Thyroid Cancer | Stage IV Follicular Thyroid Cancer | Stage IV Papillary Thyroid Cancer | Thyroid Gland Medullary Carcinoma

United States
University of Pennsylvania

Completed

Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer

Metastatic Medullary Thyroid Cancer | Metastatic Differentiated Thyroid Cancer | Metastatic Anaplastic Thyroid Cancer | Metastatic Poorly Differentiated Thyroid Cancer

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma

Medullary Thyroid Cancer

China
National Institute of Diabetes and Digestive and...

Recruiting

Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer

Non-Medullary Thyroid Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management

Advanced Thyroid Gland Medullary Carcinoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVC Thyroid Gland Medullary...

United States
European Organisation for Research and Treatment...

Completed

Nintedanib(BIBF1120) in Thyroid Cancer

Differentiated Thyroid Cancer (DTC) | Medullary Thyroid Cancer (MTC)

France, Belgium, Denmark, Italy, Netherlands, Germany, Poland, Spain, United Kingdom
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer

Multiple Endocrine Neoplasia Type 2A | Multiple Endocrine Neoplasia Type 2B | Recurrent Thyroid Gland Medullary Carcinoma | Hereditary Thyroid Gland Medullary Carcinoma | Locally Advanced Thyroid Gland Medullary Carcinoma | Sporadic Thyroid Gland Medullary Carcinoma | Stage III Thyroid Gland Medullary... and other conditions

United States
Exelixis

Completed

Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer (EXAM)

Thyroid Cancer

France, United Kingdom, United States, Spain, Austria, Israel, Portugal, Saudi Arabia, Netherlands, Greece, Canada, Brazil, Chile, Poland, Italy, Russian Federation, Sweden, Germany, Denmark, India, Switzerland, Belgium, Korea, Republic... and more
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Patient Decision Aid in Supporting Decision-Making About When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients With Medullary Thyroid Cancer and Their Caregivers

Thyroid Gland Medullary Carcinoma

United States
Sanofi

Completed

Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of Vandetanib (Vandetanib)

Medullary Thyroid Cancer

United States
Massachusetts General Hospital

Completed

Pre-Operative Nodal Staging of Thyroid Cancer Using USPIO MRI: Preliminary Study

Papillary Carcinoma of Thyroid Gland | Metastatic Medullary Thyroid Cancer | Follicular Thyroid Cancer Lymph Node Metastasis

United States
National Cancer Institute (NCI)

Active, not recruiting

Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery

Recurrent Thyroid Gland Carcinoma | Refractory Thyroid Gland Carcinoma | Stage III Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IV Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IV Thyroid Gland Papillary Carcinoma AJCC v7 | Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7 | Stage... and other conditions

United States
University Hospital, Basel, Switzerland
University Hospital, Zürich; University Hospital Freiburg; Krebsforschung Schweiz... and other collaborators

Completed

177Lu-PP-F11N in Combination With Sacubitril for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer

Thyroid Cancer, Medullary

Switzerland
Emory University
Novartis

Completed

Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer

Thyroid Cancer

United States
National Cancer Institute (NCI)

Completed

Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer

Medullary Thyroid Cancer (MTC)

United States
NantCell, Inc.
National Cancer Institute (NCI)

Unknown

QUILT-3.006 for Recurrent Medullary Thyroid Cancer

Medullary Thyroid Cancer (MTC)

United States
Dana-Farber Cancer Institute
Bayer

Active, not recruiting

A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer

Thyroid Cancer

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Molecular Profile of Metastatic Sporadic Medullary Thyroid Cancer Patients and Correlation With Vandetanib

Metastatic Sporadic Medullary Thyroid Cancer

Italy
Genzyme, a Sanofi Company

Completed

Vandetanib Risk Minimisation Effectiveness

Medullary Thyroid Cancer

Canada
Genzyme, a Sanofi Company

Completed

A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Thyroid Cancer

Italy, Spain, Romania, Netherlands, Canada, United States, Switzerland, Australia
Genzyme, a Sanofi Company

Active, not recruiting

Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment (88)

Medullary Thyroid Cancer | Locally Advanced or Metastatic Medullary Thyroid Cancer

Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Czechia, Denmark, Finland, Germany, Greece, India, Israel, Italy, Korea, Republic of, Poland, Russian Federation, Sweden, United Kingdom
M.D. Anderson Cancer Center

Recruiting

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

Recurrent Thyroid Gland Carcinoma | Poorly Differentiated Thyroid Gland Carcinoma | Thyroid Gland Anaplastic Carcinoma | Thyroid Gland Squamous Cell Carcinoma | Thyroid Gland Medullary Carcinoma | Thyroid Gland Papillary Carcinoma | Malignant Thyroid Gland Neoplasm

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cancer and Blood Pressure Management, CARISMA Study

Metastatic Renal Cell Carcinoma | Chronic Kidney Disease | Stage IV Renal Cell Cancer AJCC v8 | Cardiovascular Disorder | Metastatic Thyroid Gland Medullary Carcinoma | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVB Thyroid Gland... and other conditions

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Terminated

Ponatinib for Advanced Medullary Thyroid Cancer

Thyroid Neoplasms

United States
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer

Recurrent Thyroid Gland Carcinoma | Thyroid Gland Anaplastic Carcinoma | Stage III Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v7 | Stage IVC Differentiated Thyroid Gland Carcinoma... and other conditions

United States, Taiwan, Australia, Singapore, China
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer

Thyroid Cancer, Medullary | Thyroid Cancer | Papillary Thyroid Cancer | Differentiated Thyroid Cancer | Poorly Differentiated Thyroid Gland Carcinoma | Follicular Thyroid Cancer

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma? (DSR-MTC)

Medullary Thyroid Cancer | Lymph Node Disease | Lymph Node Metastasis | Medullary Carcinoma | Medullary Tumor | Medullary Neoplasms | Desmoplasia | Desmoplastic | Desmoplastic Reaction

Italy
University of Pennsylvania

Recruiting

GFRα4 CAR T Cells in MTC Patients

Metastatic Medullary Thyroid Cancer

United States
Cancer Institute and Hospital, Chinese Academy...
Peking University; Peking University Cancer Hospital & Institute

Recruiting

68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTC

Surgery | Medullary Thyroid Cancer | Fibroblast Activation Protein Inhibitor | Prositron Emission Tomography

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Metastatic Adrenal Gland Pheochromocytoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Locally Advanced Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Metastatic Parathyroid Gland Carcinoma and other conditions

United States
Leiden University Medical Center

Completed

Sorafenib as Adjuvant to Radioiodine Therapy in Non-Medullary Thyroid Carcinoma

Thyroid Cancer

Netherlands
Instituto do Cancer do Estado de São Paulo

Recruiting

Thermal Ablation of Cervical Metastases From Thyroid Carcinoma

Medullary Thyroid Cancer | Lymph Node Metastases | Thyroid Neoplasia | Well-Differentiated Thyroid Cancer

Brazil
Genzyme, a Sanofi Company
Worldwide Clinical Trials

Completed

Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer (Caprelsa104)

Symptomatic, Aggressive, Sporadic, Unresectable, Locally | Advanced/Metastatic Medullary Thyroid Cancer (MTC)

Belgium, Italy, Netherlands, Spain, France, Germany, United Kingdom, Luxembourg
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine Cancer

Thyroid Gland Medullary Carcinoma | Differentiated Thyroid Gland Carcinoma | Malignant Adrenal Gland Pheochromocytoma | Malignant Paraganglioma

United States
M.D. Anderson Cancer Center
Novartis Pharmaceuticals

Terminated

Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma

Solid Tumor | Thyroid Cancer

United States
Icahn School of Medicine at Mount Sinai

Terminated

Personalized Cancer Therapy for Patients With Metastatic Medullary Thyroid or Metastatic Colon Cancer

Colon Cancer | Medullary Thyroid Cancer

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer (DOPMET)

Thyroid Carcinoma | Thyroid Neoplasm | Medullary Carcinoma

France
Radboud University Medical Center

Completed

Digoxin for the Reinduction of Radioiodine Uptake in Metastatic or Locally Advanced Non-medullary Thyroid Carcinoma (DIGUP-TC)

Non-Medullary Thyroid Carcinoma

Netherlands
Blueprint Medicines Corporation

Approved for marketing

Pre-Approval Access Program (PAAP) for Pralsetinib (BLU-667) in Patients With Unresectable or Metastatic NSCLC or MTC

Non-Small Cell Lung Cancer | Medullary Thyroid Cancer
Power Life Sciences Inc.

Not yet recruiting

A Detailed Look At What Patients Experience In Medullary Thyroid Cancer Clinical Study

Medullary Thyroid Cancer

United States
Hoffmann-La Roche

Withdrawn

A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC). (AcceleRET-MTC)

Medullary Thyroid Cancer

Spain
Genzyme, a Sanofi Company

Active, not recruiting

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

Thyroid Cancer

United States, Australia, Austria, Belgium, Brazil, Canada, Czechia, Denmark, France, Germany, Hungary, India, Italy, Korea, Republic of, Mexico, Netherlands, Poland, Portugal, Romania, Russian Federation, Serbia, Spain, Sweden, Switz...
Exelixis

Active, not recruiting

A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancer (EXAMINER)

Medullary Thyroid Cancer

Australia, France, Israel, Spain, Russian Federation, Netherlands, Hungary, Korea, Republic of, Croatia, Italy, Canada, Poland, Romania, Sweden
Jonsson Comprehensive Cancer Center

No longer available

68Ga DOTATATE PET/CT in Neuroendocrine Tumors (Expanded Access)

Neuroendocrine Tumors | Medullary Thyroid Cancer | Carcinoid Cancer | Cancers Expressing Somatostatin Receptors

United States
Boston Pharmaceuticals

Completed

Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors

Advanced Nonhaematologic Malignancies

United States, Korea, Republic of, Taiwan, France, Hong Kong, Belgium, Spain

Clinical Trials on Thyroid Cancer, Medullary

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