Clinical Trials on Treatment Adverse Effect

Total 5878 results

Lei Li

Recruiting

Long-acting G-CSF for Febrile Neutropenia

Febrile Neutropenia | Epithelial Ovarian Cancer | Adverse Event | Cost-effectiveness | Myelosuppression Adult | Colony Stimulating Factors

China
Indiana University

Recruiting

Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

Coronary Artery Disease | Cisplatin Adverse Reaction | Lipid Disorder | Survivorship | Hypogonadism, Male | Testicular Cancer | Bone Marrow Transplant Complications | ASCVD

United States
Rigshospitalet, Denmark
Aarhus University Hospital

Completed

Use of Prone Position Ventilation in Danish Patients With COVID-19 Induced Severe ARDS Treated With VV-ECMO

Extracorporeal Membrane Oxygenation | ARDS, Human | Adverse Event | Prone Position | COVID-19 Acute Respiratory Distress Syndrome

Denmark
Telios Pharma, Inc.

Active, not recruiting

Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | Relapsed/Refractory B Cell Malignancies | Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma | Treatment-Naive B Cell Malignancies

United States, Poland, Ukraine, Hungary, Italy, Russian Federation, United Kingdom
Azienda Usl di Bologna
Lorenzo Gamberini

Completed

Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome

COVID-19 | Quality of Life | Sedation | Mechanical Ventilation | Complication of Treatment | Radiologic Increased Density of Lung

Italy
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Massachusetts Eye and Ear Infirmary

Completed

Collision Warning Device for Blind and Visually Impaired

Glaucoma | Retinitis Pigmentosa | Blindness | Hemianopsia | Hemianopia | Peripheral Visual Field Defect

United States
University Medical Center Groningen
University of Sao Paulo; Dokkyo Medical University; Somogy Megyei Kaposi Mór... and other collaborators

Unknown

Beam Walking Across the Lifespan for Falls Prediction (BEAM)

Stroke | Parkinson Disease | Cognitive Impairment | Dementia | Aging | Postural; Defect | Diagnoses Disease

Netherlands, Brazil, Germany, Hungary, Japan
Fujian Cancer Hospital

Not yet recruiting

the Efficacy and Safety of Dalpiciclib Combined With Third-generation EGFR-TKI in Patients With EGFR Mutation and Meningial Metastasis in Non-small Cell Lung Cancer Progressing Through Third-generation TKI and Platinum-containing Two-drug Chemotherapy

Non-small Cell Lung Cancer Confirmed by Histopathology or Cytology | The TNM (8th) Phase is IV | With EGFR Mutations | Meningeal Progression Occurred After Previous Platinum-containing Two-drug Chemotherapy and Third-generation EGFR-TKI Treatment | Male or Female | The Age of 18 Years Old or... and other conditions
City of Hope Medical Center
National Cancer Institute (NCI); National Institute of Nursing Research (NINR)

Completed

Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family Caregivers

Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Caregiver | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer | Psychological Impact of Cancer and Its Treatment

United States
Maimonides Medical Center

Recruiting

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome (PWS-GXR)

Aggression | Behavioral Symptoms | Pathologic Processes | Nervous System Diseases | Obesity | Neurologic Manifestations | Neurobehavioral Manifestations | Congenital Abnormalities | Overnutrition | Nutrition Disorders | Genetic Diseases, Inborn | Intellectual Disability | Self-Injurious Behavior | Abnormalities, Multiple and other conditions

United States
Children's Oncology Group

Recruiting

Molecular Epidemiology of Pediatric Germ Cell Tumors

Teratoma | Choriocarcinoma | Germinoma | Germ Cell Tumor | Yolk Sac Tumor | Embryonal Carcinoma | Mixed Germ Cell Tumor | Late Effects | Pediatric Germ Cell Tumor

United States
Celularity Incorporated

Active, not recruiting

Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma

Cardiovascular Diseases | Vascular Diseases | Neoplasms | Immune System Diseases | Neoplasms by Histologic Type | Lymphoproliferative Disorders | Immunoproliferative Disorders | Hematologic Diseases | Hemorrhagic Disorders | Multiple Myeloma | Paraproteinemias | Blood Protein Disorders | Antineoplastic Agents | Physiological... and other conditions

United States
Ramathibodi Hospital

Completed

The Association Between Respiratory Effort Parameters During the First 48 Hours With Clinical Outcomes in Mechanically Ventilated Patients: A Prospective Observational Study. (EFFORT-1)

Respiratory Distress Syndrome | Lung Mechanics | Respiratory Effort

Thailand
Taewoong Medical Co., Ltd.

Active, not recruiting

Pulsta® Transcatheter Pulmonary Valve Korean Multicenter Study

Pulmonary Valve Stenosis | Congenital Heart Defect | Pulmonary Valve; Insufficiency, Congenital

Korea, Republic of
Marmara University
National Institute of Allergy and Infectious Diseases (NIAID)

Unknown

Transcriptome and Metabolic Analyses of CHAPLE Disease (CHAPLEOMIC)

Protein-Losing Enteropathies | CD55 - Cluster of Differentiation Antigen 55 Deficiency | Primary Intestinal Lymphangiectasis | Complement Regulatory Factor Defect

Turkey
Hacettepe University

Not yet recruiting

An Investigation of the Cervical Region Biomechanics in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Cough | Cervical Pain | Postural; Defect

Turkey
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Centre Hospitalier Universitaire de Tivoli

Recruiting

To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery

Lung Diseases | Urologic Neoplasms | Abdominal Hernia | Abdominal Wall Defect | Abdominal Neoplasm | Urogenital Disease | Thoracic Diseases

Belgium
University of Utah

Terminated

Nickel Allergy With Septal Closure Devices (NASAH)

Atrial Septal Defect | Patent Foramen Ovale | Allergic Reaction to Nickel

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Application of BHOHB SPINAL-METER and CervicalMeter for Posture Assessment (BHOHB)

Parkinson Disease | Scoliosis | Osteoporosis | Postural; Defect

Italy
Charite University, Berlin, Germany
Arda Can Cetindag; Lukas Preis

Withdrawn

The Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer's Disease

Alzheimer Disease | Sleep Apnea | Sleep Deprivation | Blood Brain Barrier Defect

Germany
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Epidemiology of Persistent Pulmonary Hypertension of the Newborn - SCOR in Lung Biology and Diseases in Infants and Children

Heart Diseases | Cardiovascular Diseases | Lung Diseases | Persistent Fetal Circulation Syndrome | Defect, Congenital Heart
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Istituto Auxologico Italiano
IRCCS Fondazione Stella Maris; Azienda Ospedaliero, Universitaria Meyer

Completed

Multisensory Telerehabilitation for Visual Field Defects (MUST)

Brain Injuries | Hemianopia | Visual Field Defect Following Cerebrovascular Accident

Italy
University of Southern California

Active, not recruiting

Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)

Delayed Cerebral Ischemia | Vasospasm, Intracranial | Aneurysm, Ruptured | Blood Brain Barrier Defect

United States
University of Bergen
Haukeland University Hospital

Completed

Oral Health Intervention Program for Children With Congenital Heart Defects

Dental Caries in Children | Dental Plaque | Congenital Heart Defect | Dental Erosion | Hypomineralization, Tooth
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genes Causing Ebstein's Anomaly

Heart Defects, Congenital | Double Outlet Right Ventricle | Heart Septal Defects, Ventricle | Truncus Arteriosus, Persistent

United States, Belarus, Ukraine
Cliniques universitaires Saint-Luc- Université...

Active, not recruiting

PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock (PLACCSEPS)

Covid19 | Septic Shock | Inflammatory Response | Disseminated Intravascular Coagulation | Platelet Signal Processing Defect | Neutrophil Extracellular Trap Formation

Belgium
Zhongshan Bo Ai Hospital

Completed

The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome

The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group; | At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether; | 534... and other conditions

China
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
Polish Lymphoma Research Group
AstraZeneca

Active, not recruiting

Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) (ACALLO)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Adverse Event | Chronic Graft-versus-host-disease | Response Rate

Poland
Christopher C. Thompson, MD, MSc

Enrolling by invitation

Endoscopic Metabolic and Bariatric Therapies (EMBTs)

Obesity | Abdominal Pain | Weight Loss | Obesity, Morbid | Complication of Surgical Procedure | Weight Gain | Bariatric Surgery Candidate | Complication,Postoperative | Abdominal Obesity | Complication of Treatment | Roux-en-y Anastomosis Site | Ulcer, Gastric | Obesity Associated Disorder | Leak, Anastomotic | Fistula... and other conditions

United States
Taipei Veterans General Hospital, Taiwan

Unknown

Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base

Quality of Life | Acupuncture | Neuromuscular Blockade | Complication of Treatment | Tumor, Brain | Skull Base Tumor | Cerebellopontine Angle Tumor

Taiwan
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
University of Saskatchewan

Completed

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

Pathologic Processes | Postoperative Complications | Sleep Disordered Breathing | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Tonsillectomy | Respiratory Depression | Analgesics, Opioid | Pulse Oximetry | Lidocaine | Analgesics | Gabapentin | Narcotics | Obstructive Sleep Apnea of Child | Physiologic Effects...

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy (LIPOPHILL)

HIV Infection | Antiretroviral Side Effects | Lipodystrophy Syndrome Related to HIV Infection

France
Hospital Civil de Guadalajara

Recruiting

Reverse Trigger Phenotypification and Response to Ventilatory Adjustments (RT-CHASERS)

Acute Respiratory Distress Syndrome | Mechanical Ventilation | Reverse Trigger

Mexico
University of Zurich

Unknown

Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROGENE)

Pustular Psoriasis | Erosive Pustular Dermatosis of the Scalp | Behcet's Disease | Dermatitis Herpetiformis | Pyoderma Gangrenosum | Linear IgA Bullous Dermatosis | Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue | Sweet's Syndrome | Bowel-associated Dermatosis-arthritis Syndrome | Acute Generalized Exanthematous Pustulosis and other conditions

Switzerland
University of Rochester
Rochester Institute of Technology

Recruiting

Vision Loss Impact on Navigation in Virtual Reality

Stroke, Ischemic | Stroke Hemorrhagic | Hemianopia, Homonymous | Visual Field Defect, Peripheral | Hemianopsia | Hemianopia | Quadrantanopia | Occipital Lobe Infarct | Hemianopsia, Homonymous | Vision Loss Partial | Quadrantanopsia

United States
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Hydrops: Diagnosing & Redefining Outcomes With Precision Study (HyDROPS)

Hydrops Fetalis | Birth Defect | Fetal Anomaly

United States
Hacettepe University

Recruiting

Investigation of Arm Swings Characteristics in Patient With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Postural; Defect | Dyspnea | Gait, Unsteady

Turkey
Poitiers University Hospital

Completed

Muscular Respiratory Involvement and Systemic Sclerosis (SIROCO)

Respiratory Insufficiency | Systemic Sclerosis | Pulmonary Function Test | Diaphragm Defect | Muscular Weakness | Diaphragmatic Electromyography

France
Sun Yat-sen University

Recruiting

GM1 Prophylaxis for WBRT Related Cognitive Dysfunction (GLORY)

Breast Cancer | Cognitive Impairment | Brain Metastases | Radiotherapy Side Effect | Gangliosidosis, GM1

China
Karolinska Institutet

Recruiting

Immune Cells in Diabetic Chronic Foot Ulcers

Diabetic Foot | Immune Defect

Sweden
Jena University Hospital

Active, not recruiting

Visualizing Regional Lung Ventilation in Patients With Postacute-COVID-19 (ViReVentPoCov)

COVID-19 | Post-acute COVID-19 Syndrome | Electric Impedance Tomography | Ventilatory Defect

Germany
Aditya Kaza
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Optical Tissue Identification for Myocardial Architecture (OPTIMA)

Complete Atrioventricular Canal | Ventricular Septal Defect | Tetralogy of Fallot With Pulmonary Stenosis

United States
Medical University of Graz

Completed

Natural Versus Synthetic Vitamin B Complexes in Human

Healthy | Oxidative Stress | Vitamin B 12 Deficiency | Polyphenols | Thiamine and Niacin Deficiency States | Pyridoxine Deficiency | Folic Acid Deficiency Anemia, Dietary | Peroxidase; Defect | Homocystine; Metabolic Disorder

Austria
Children's Hospital of Philadelphia
Cigna Foundation

Completed

Impact of Serious Pediatric Illness on Parent and Sibling Health

Family Members of: Newborns Extremely Premature | Family Members of: New Pediatric Oncology Patients | Family Members of: Critical Congenital Heart Defect Patients | Family Members of: Children Severe Neurological Impairment

United States

Clinical Trials on Treatment Adverse Effect

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Croatia

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Rare Diseases

Drug Interventions

Dietary Supplements

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