Search clinical trials for: ABP-450

Total 15352 results

Hoffmann-La Roche

Completed

A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802

Healthy Volunteer

United States
Nivalis Therapeutics, Inc.
Davita Clinical Research

Completed

A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects

Drug Interaction Potentiation

United States
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection: Canada

HIV Infection

Canada
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Rifampin on the Pharmacokinetics of PCI-32765 in Healthy Participants

Healthy Participants

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Safety and Pharmacokinetics of Single and Multiple Dose Rifampin in Infants

Infection

United States
Bamrasnaradura Infectious Diseases Institute
Thai Red Cross AIDS Research Centre; Clinical Research Collaborative Network

Completed

Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity

Treatment Failure, HIV or AIDS | CD4 Cell Counts

Thailand
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy
AbbVie

Completed

The Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 4, 5, or 6 Infection (ENDURANCE-4) (ENDURANCE-4)

Hepatitis C Virus
ProFem GmbH
Montavit Ges.m.b.H.

Active, not recruiting

A Phase IIb/III Study of Prof-001 for the Treatment of Patients With Recurrent Vulvovaginal Candidiasis (RVVC)

Recurrent Vulvovaginal Candidiasis

Austria, Poland, Slovakia
Central Finland Hospital District
Biosense Webster, Inc.

Unknown

Medical ANtiarrhythmic Treatment or Radiofrequency Ablation in Ischemic Ventricular Tachyarrhythmias (MANTRA-VT)

Myocardial Infarction | Ventricular Tachyarrhythmia

Finland
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

PLATFORM Study of Precision Medicine for Rare Tumors

Rare Tumor
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Tuberculosis Infection | Pediatric HIV Infection

Nigeria
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of HRS-1167 in Healthy Subjects

Advanced Solid Tumor

China
Institute of Tropical Medicine, Belgium
Leiden University Medical Center; Damien Foundation; Instituto Fernandes Figueira and other collaborators

Completed

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

Leprosy

Comoros, Madagascar
Amgen

Completed

A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants

Healthy Participants

United States
Phathom Pharmaceuticals, Inc.

Withdrawn

Evaluation of Effect of Rifampin on the Pharmacokinetics of Vonoprazan in Healthy Participants

Healthy Participants

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of Baricitinib and Rifampicin in Healthy Participants

Healthy Volunteers

United Kingdom
National University Hospital, Singapore

Suspended

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers

Tuberculosis

Singapore
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
Janssen Research & Development, LLC

Completed

A Drug Interaction Study in Healthy Participants to Assess the Effect of Rifampin on the Pharmacokinetics of JNJ-42847922

Healthy

United States
Bristol-Myers Squibb

Withdrawn

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Cancer

United States
University Medicine Greifswald

Completed

Impact of Two Genetic Variants of OATP1B3 or MRP2 or Rifampin on Systemic Disposition and Biological Efficacy of CCK-8

Gastrointestinal Hormones

Germany
Pfizer

Completed

Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics

Healthy Volunteers

United States
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Unknown

BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection (BREATHER)

HIV

United Kingdom, Uganda, Ireland, United States, France, Germany, Thailand, Ukraine
Pfizer
ViiV Healthcare

Terminated

A Long Term Safety Study Of Lersivirine For The Treatment Of HIV-1 Infection In Subjects Who Have Completed Treatment With Lersivirine In Studies A5271015 And A5271022

HIV-1

South Africa, Australia, United Kingdom, Canada, Italy, Poland, Switzerland, Mexico, Brazil
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
Michael Hoelscher
Quintiles, Inc.; German Federal Ministry of Education and Research; Parexel; European... and other collaborators

Completed

Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB (SQ109EBA)

Tuberculosis, Pulmonary

South Africa
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.

Rheumatoid Arthritis | Healthy Volunteers

United States
Bristol-Myers Squibb
PRA Health Sciences

Completed

Drug-Drug Interaction Study With Rifampin

Alzheimer Disease

India
Institut Bergonié

Unknown

Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Pancreatic Cancer

France
Bristol-Myers Squibb

Completed

Study Switching HIV-1 Infected Patients With an Undetectable Viral Load on a First Protease Inhibitor-Based Regimen to an Efavirenz-Based Regimen

HIV Infections

United States, Puerto Rico
AbbVie

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With HCV Who Failed a Prior DAA Containing Therapy

Chronic Hepatitis C | Hepatitis C Virus | HCV | Direct-Acting Antiviral Agent (DAA)-Experienced
Acerta Pharma BV

Completed

A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants

Healthy Participants

United States
Abbott

Completed

Evaluation of Kaletra Therapy Over the Long-term

Human Immunodeficiency Virus

Germany
Abbott

Completed

A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat Hepatitis C

HCV Infection

United States
Gulhane School of Medicine

Completed

The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism

Hypogonadotrophic Hypogonadism

Turkey
Eisai Inc.

Completed

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Healthy Participants

United States
Nanfang Hospital, Southern Medical University

Recruiting

Rapid Improvement of Depression of Fluoxetine Combined With ATP

Depression

China
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

Effect of Clarithromycin and Rifampicin on the Pharmacokinetics of XZP-3287 in Healthy Subjects

Healthy

China
Actelion

Completed

A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects

Healthy Subjects

Germany
Tourcoing Hospital

Recruiting

Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR (RIFAMAB)

Prosthetic Infection

France
University of Cape Town

Recruiting

High vs. Standard Dose Rifampicin for Effusive Tuberculous Pericarditis (IMPI-3)

HIV Status | Tuberculous Pericarditis

South Africa
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood

Healthy

Germany
Rennes University Hospital

Completed

EVRIOS : Comparative Evaluation of Low Versus High Doses of Rifampicin (EVRIOS)

Osteoarticular Infection

France
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Rifampin Effect Study of SHR2554 on Healthy Chinese Adult Subjects

Healthy

China
Peking Union Medical College Hospital

Unknown

Efficacy of Efavirenz 400mg vs. 600mg Combined With Lamivudine and Tenofovir in Treatment Naive HIV Infection

HIV/AIDS | Mental Impairment

China
AstraZeneca

Completed

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Rifampicin Pharmacokinetics Effect on Fluzoparib

Healthy Male Subjects

China

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