Search clinical trials for: Adalimumab plus Methotrexate

Total 6670 results

IRCCS Policlinico S. Matteo

Completed

Prospective Study on Intensive Early Rheumatoid Arthritis Treatment (CURE)

Rheumatoid Arthritis

Italy
Sun Yat-sen University

Recruiting

Adalimumab Plus Methotrexate for the Treatment of Pediatric Uveitis

Uveitis

China
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
Pfizer

Completed

Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Mexico, Argentina, Chile, Croatia, Czech Republic, Hungary, Poland, Puerto Rico
Pfizer

Completed

Study Of PF-06410293 And Adalimumab In Healthy Subjects (REFLECTIONS B538-01)

Healthy

United States, Belgium
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Rheumatoid Arthritis

Germany, Italy, Spain, United States, France, Sweden, Greece, Russian Federation, Denmark, Finland, Netherlands, Puerto Rico
Pfizer

Completed

A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira) In Healthy Subjects (REFLECTIONS B538-07)) (B538-07)

Healthy Subjects

United States
Hospital San Carlos, Madrid

Recruiting

Efficacy, Safety and Costs of Methotrexate, Adalimumab, or Their Combination in Non-infectious Non-anterior Uveitis (Co-THEIA)

Uveitis

Spain
AbbVie (prior sponsor, Abbott)

Completed

Study to Determine the Effects of Different Doses of Methotrexate (MTX) When Taken With Adalimumab in Subjects With Early Rheumatoid Arthritis (RA) (CONCERTO)

Early Rheumatoid Arthritis

United States, Argentina, Austria, Belgium, Canada, Czech Republic, Germany, Poland, Puerto Rico, Spain
Abbott

Completed

Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis (OPTIMA)

Rheumatoid Arthritis

United States, Argentina, Australia, Austria, Belgium, Canada, Czech Republic, France, Germany, Hungary, Mexico, Netherlands, New Zealand, Norway, Poland, Puerto Rico, Slovakia, South Africa, Spain, Sweden, United Kingdom
AbbVie (prior sponsor, Abbott)
Pharma Consulting Group AB

Completed

A Pilot Study of the Feasibility of Discontinuation of Adalimumab in Stable Rheumatoid Arthritis Patients in Clinical Remission (ADMIRE)

Arthritis, Rheumatoid

Sweden
Abbott

Completed

Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Abbott
Eisai Limited

Completed

Adalimumab Administered in Korean Rheumatoid Arthritis Subjects Treated With Methotrexate

Rheumatoid Arthritis
AbbVie

Completed

A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL) (CONTROL)

Psoriatic Arthritis

United States, Australia, Brazil, Bulgaria, Canada, Colombia, Czechia, Germany, Italy, Poland, Puerto Rico, Qatar, Spain, United Kingdom
Abbott

Withdrawn

Safety and Effectiveness and Effect on Quality of Life and Work Productivity of Humira in Patients With Psoriatic Arthritis in Clinical Routine (ELAN)

Psoriatic Arthritis
Abbott

Completed

Study of Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Idiopathic Arthritis (JIA)

Arthritis, Juvenile Idiopathic

United States, Belgium, Czech Republic, France, Germany, Italy, Slovakia, Spain
Shanghai Henlius Biotech

Completed

Phase I Study of HLX3 vs Adalimumab in Chinese Healthy Subjects

Immune System Disorder

China
CSL Behring

Completed

Phase IIB Rheumatoid Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to Methotrexate

Rheumatoid Arthritis

Italy, Japan, Taiwan, United States, Spain, Argentina, Belgium, Germany, Korea, Republic of, Czechia, Russian Federation, France, Mexico, Poland, South Africa, Hungary, Brazil, Canada, Netherlands
Abbott

Completed

Remission in Subjects With Crohn's Disease, 1 Year Phase (CLASSICII)

Crohn's Disease

United States
Turgut İlaçları A.Ş.

Completed

Comparative Pharmacokinetic, Safety, Tolerability and Immunogenicity Study of Adalimumab in Healthy Subjects

Healthy Participants

Germany
Mylan Inc.
Mylan GmbH

Completed

MYL-1401A Efficacy and Safety Comparability Study to Humira®

Psoriasis | Arthritis, Psoriatic

Bulgaria, Estonia, Hungary, Poland, Russian Federation, Ukraine
Abbott

Completed

Safety and Effectiveness of Adalimumab in Patients Diagnosed With Rheumatoid Arthritis (DALI)

Rheumatoid Arthritis

Spain
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United States, Germany, Hungary, Bulgaria, Mexico, Peru, Chile, Romania, Spain
AbbVie (prior sponsor, Abbott)

Completed

The Usability and Injection Time of the Physiolis Syringe and Autoinjector in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

United States
Sandoz
Hexal AG

Completed

Study to Demonstrate Equivalent Efficacy and to Compare Safety of Biosimilar Adalimumab (GP2017) and Humira (ADACCESS)

Plaque Type Psoriasis

United States, France, Bulgaria, Slovakia
Abbott

Completed

Safety and Efficacy of Adalimumab in Patients With Active Ankylosing Spondylitis

Ankylosing Spondylitis

Canada
Abbott

Completed

Human Anti-tumor Necrosis Factor (TNF) Monoclonal Antibody Adalimumab in Subjects With Active Ankylosing Spondylitis (ATLAS)

Ankylosing Spondylitis

United States
Sohag University

Not yet recruiting

Effect of Adalimumab Therapy on Psoriasis Patient

Psoriasi

Egypt
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis (PREMIER)

Early Rheumatoid Arthritis

United States, Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, Norway, Slovakia, Spain, Sweden, Switzerland, United Kingdom
Abbott

Terminated

Open-Label Steroid Reduction Study of Adalimumab With Methotrexate in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Alvotech Swiss AG

Completed

Pharmacokinetic, Efficacy, Safety, and Immunogenicity of AVT02 With Moderate to Severe Chronic Plaque Psoriasis

Plaque Psoriasis

Poland, Georgia, Iceland, Russian Federation, Ukraine
AbbVie (prior sponsor, Abbott)

Completed

A Study in Rheumatoid Arthritis (RA) Patients to Compare Two Formulations of Adalimumab for Pharmacokinetic, Pharmacodynamic and Safety

Rheumatoid Arthritis

United States, Belgium, Czech Republic, Germany, Puerto Rico, Romania, Slovakia
Abbott

Terminated

Evaluation of Quality of Life Changes in Puerto Rican Subjects With Active Rheumatoid Arthritis Treated With Humira (VIVIR)

Rheumatoid Arthritis

Puerto Rico
Boehringer Ingelheim

Completed

Pharmacokinetics and Safety in Healthy Volunteers

Healthy

Belgium, New Zealand
Abbott

Completed

A Canadian Open-Label Access Program to Evaluate Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriasis (PRIDE)

Psoriasis

Canada
Centre for Human Drug Research, Netherlands
Leiden University Medical Center; Leiden Academic Center for Drug Research,...

Completed

Adalimumab Microneedles in Healthy Volunteers

Pain | Injection Site

Netherlands
Synermore Biologics Co., Ltd.

Completed

Comparison of the Safety and PK of SYN060 to Humira® in Healthy Adult Subjects

Arthritis, Rheumatoid

Australia
Abbott

Completed

Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Sandoz
Hexal AG

Completed

Clinical Trial to Compare Treatment With GP2017 and Humira® in Patients With Rheumatoid Arthritis (ADMYRA)

Rheumatoid Arthritis

United States, United Kingdom, Hungary, Italy, Malaysia, Serbia, Mexico, Spain, Czechia, Poland, Germany, Romania, Russian Federation
Abbott

Completed

Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severely Active Psoriatic Arthritis Subjects With Inadequate Response to Disease Modifying Anti-Rheumatic Drug Therapy

Arthritis | Psoriatic
AbbVie (prior sponsor, Abbott)

Completed

A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis

Enthesitis Related Arthritis (ERA)
Abbott

Completed

Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis

Arthritis | Psoriatic
Abbott

Completed

Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis

Uveitis
Tufts Medical Center

Completed

Mechanism of Action Study for Psoriasis (MOA)

Psoriasis

United States
Pariser, Robert J., M.D.
Abbott; Virginia Clinical Research, Inc.

Completed

A Study of Adalimumab to Treat Sarcoidosis of the Skin

Sarcoidosis

United States
Florida Academic Dermatology Centers
Abbott

Completed

To Assess the Efficacy and Safety of Adalimumab in Subjects With Moderate to Severe Hidradenitis Suppurativa (HIDRI2007)

Hidradenitis Suppurativa
University Hospital, Tours

Completed

Positron Emission Tomography in Rheumatoid Arthritis With Adalimumab (PETRA) (PETRA)

Rheumatoid Arthritis

France
Abbott

Completed

Safety and Efficacy Study of Adalimumab in Patients With Active Psoriatic Arthritis (PsA) (STEREO)

Psoriatic Arthritis

United States
Samsung Bioepis Co., Ltd.
Organon and Co

Completed

Pharmacokinetics, Efficacy, Safety, and Immunogenicity of SB5 Versus Humira in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Plaque Psoriasis

Czechia, Lithuania, Poland, Bulgaria

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