Search clinical trials for: Antipruritics

Total 1059 results

Bausch & Lomb Incorporated

Completed

Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.

Allergic Conjunctivitis

United States
Emergent BioSolutions
GlaxoSmithKline

Completed

Effect of Raxibacumab on Immunogenicity of Anthrax Vaccine Adsorbed

Infections, Bacterial

United States
University of Florida

Completed

Improving Diagnostic Standards in Dysphagia

Dysphagia

United States
Semmelweis University

Completed

Acute Oral Effects of Heated Tobacco Products

Nicotine Dependence, Cigarettes

Hungary
Washington University School of Medicine

Terminated

Pgp Transporter and CNS Biodistribution of Ondansetron in Healthy Volunteers

Neuropathic Pain

United States
M.D. Anderson Cancer Center
Sancuso

Completed

Oral Ondansetron Versus Transdermal Granisetron (Sancuso) for Women With Cervical, Endometrial or Vaginal Cancer Receiving Pelvic Chemoradiation

Cancer of the Cervix

United States
Eisai Inc.

Completed

Pilot Study to Assess Palonosetron Versus Ondansetron as Rescue Medication in Subjects That Develop Postoperative Nausea and Vomiting (PONV) in the Postanesthesia Care Unit (PACU)

Postoperative Nausea and Vomiting

United States
Rafa Laboratories
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

Comparison of Delta-8-THC to Ondansetron in the Prevention of Acute Nausea From Moderately Emetogenic Chemotherapy

Cancer

Israel
Charite University, Berlin, Germany

Terminated

Chronic Urticaria - Long Term Assessment of Effects of Rupatadine

Chronic Urticaria

Germany
RedHill Biopharma Limited

Completed

Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Tablets) for Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)

Irritable Bowel Syndrome With Diarrhea

United States
UConn Health

Completed

Effects of Electronic Cigarettes on Nicotine Concentrations (ECIG)

Health Behavior

United States
Merck Sharp & Dohme LLC

Completed

2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-091)

Postoperative Nausea and Vomiting
Merck Sharp & Dohme LLC

Completed

Efficacy & Safety of Loratadine-Betamethasone Oral Solution for Treatment of Severe Perennial Allergic Rhinitis in Children (Study P03428)

Rhinitis
Bioprojet

Terminated

First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375

Healthy Male Volunteers

Netherlands
Women's College Hospital

Terminated

Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting

Ambulatory Gynecological Laparoscopic Procedures

Canada
NeurogesX

Completed

Study of NGX-4010 With the Use of Open Label Lidocaine (2.5%)/Prilocaine (2.5%) Cream for the Treatment of Postherpetic Neuralgia (PHN)

Postherpetic Neuralgia

United States
Kinnov Therapeutics

Not yet recruiting

A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

Alcohol Use Disorder
The Second Affiliated Hospital of Chongqing Medical...
Xiangya Hospital of Central South University; West China Hospital; Chongqing... and other collaborators

Recruiting

Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and Ondansetron

Postoperative Nausea and Vomiting

China
Federal State Budgetary Scientific Institution,...

Not yet recruiting

Diphenhydramine Ointment for Knee Osteoarthritis

Osteoarthritis

Russian Federation
Laval University
CHU de Quebec-Universite Laval

Not yet recruiting

ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY

Hypotension | Cesarean Section | Anesthesia; Adverse Effect, Spinal and Epidural
Adial Pharmaceuticals

Completed

Study to Evaluate AD04 in Adults With Alcohol Use Disorder (AUD) and Selected Serotonin Transporter Polymorphisms (ONWARD)

Alcohol Use Disorder

Bulgaria, Croatia, Estonia, Finland, Latvia, Poland, Sweden
Stanford University
Thomas Jefferson University; Santa Clara Valley Medical Center

Completed

Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women (AIM2NAS)

Neonatal Abstinence Syndrome | Narcotic Addiction

United States
Organon and Co

Completed

Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)

Rhinitis, Allergic
University of Virginia
National Institute on Drug Abuse (NIDA)

Completed

New Medication Treatment for Stimulant Dependence

Cocaine Dependence

United States
Mahidol University

Completed

Effect of Anti-histamine in Prevention Systolic Hypotension After Protamine

Protamine Adverse Reaction

Thailand
University of Colorado, Denver
National Institute of Mental Health (NIMH)

Completed

Addition of Ondansetron to Ongoing Antipsychotic Treatment for Schizophrenia

Schizophrenia

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

Pruritus

Belgium
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Stanford University

Completed

Palonosetron and Hydroxyzine to Reduce Opioid Withdrawal

Substance-Related Disorders

United States
Merck Sharp & Dohme LLC

Completed

2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-090)(COMPLETED)

Postoperative Nausea and Vomiting
Purdue Pharma LP

Completed

Experimental Biomarker Study for Pain Thresholds

Pain

Denmark
IRCCS Burlo Garofolo
Mario Negri Institute for Pharmacological Research; Agenzia Italiana del Farmaco

Completed

Symptomatic Treatment of Acute Gastroenteritis

Gastroenteritis | Vomiting | Acute Gastroenteritis

Italy
Medical University of Gdansk

Completed

Droperidol and Cardiac Repolarization

Cardiac Repolarization

Poland
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Withdrawn

Aprepitant or Ondansetron in Treating Nausea and Vomiting Caused By Opioids in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myeloproliferative Disorders | Solid Tumor | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Nausea and Vomiting
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Ondansetron Tablets USP 8 mg Under Fed Condition

Fed

India
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Ondansetron Tablets USP 8 mg Under Fasting Condition

Fasting State

India
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study for Ondansetron Hydrochloride Tablets 8 mg Under Fed Condition

Healthy

India
Tata Memorial Hospital

Completed

Granisetron Versus Ondansetron: Comparative Effects on ECG, QTc

Prolonged QTc Interval

India
University of Texas Southwestern Medical Center
Stanley Medical Research Institute

Completed

Ondansetron for Bipolar Disorder and Alcohol Use Disorders

Bipolar Disorder | Alcohol Use Disorder | Dual Diagnosis

United States
The University of Texas Health Science Center at...

Completed

EMS Use of Isopropyl Alcohol Aromatherapy Versus Ondansetron

Nausea

United States
University of Nottingham
Arthritis Research UK Pain Centre; Nottingham University Hospitals Charity

Completed

Ibuprofen Gel or Capsaicin Cream for my Painful Knee Osteoarthritis?

Osteoarthritis, Knee

United Kingdom
Siriraj Hospital
Buddhachinaraj Hospital

Completed

Comparison of IV Fluid Loading and Ondansetron in Reduction of PONV After LC

Postoperative Nausea and Vomiting | Postoperative Nausea | Postoperative Vomiting

Thailand
University Hospital, Mahdia

Completed

Effects of Ondansetron on Hemodynamics in Cesarean Section Under Spinal Anesthesia (EffOnd)

Cesarean Section | Spinal Anesthesia | Hemodynamics | Ondansetron

Tunisia
Takeda

Terminated

Evaluation of TAK-058 and Ondansetron on P50 Auditory Gating in Participants With Stable Schizophrenia

Schizophrenia

United States
Emory University

Completed

Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department

Nausea and Vomiting

United States
Accenture

Completed

A Study of Vestipitant (GW597599) in the Treatment of Breakthrough Postoperative Nausea and Vomiting (PONV)

Postoperative Nausea and Vomiting

United States
Lakehead University

Completed

Diphenhydramine and Sweating (BENEXE2022)

Hyperthermia | Allergic Rhinitis | Diphenhydramine Causing Adverse Effects in Therapeutic Use | Sweating

Canada
Acibadem University

Completed

Interaction Between Tramadol and Ondansetron

Cholecystectomy, Laparoscopic

Turkey
Cheerain HK Limited

Completed

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers

Electronic Cigarette Use

United States
Ataturk University

Completed

The Effect of Intravenous Granisetron and Ondansetron in Patients Undergoing Cesarean Section

Postoperative Complications | Hypotension | Vomiting, Postoperative

Turkey

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