Search clinical trials for: Bypassing agents

Total 188687 results

Hoffmann-La Roche

Completed

A Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), and Safety Outcomes in Patients With Hemophilia A Treated With Standard-of-Care Treatment

Hemophilia A

United States, Korea, Republic of, Italy, South Africa, Spain, China, Japan, Poland, Australia, Costa Rica, Germany, Taiwan
Genzyme, a Sanofi Company

Completed

A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors (ATLAS-INH)

Hemophilia A | Hemophilia B

United States, Australia, Canada, China, France, Korea, Republic of, Malaysia, Turkey, Ukraine, United Kingdom, Germany, India, Italy, Japan, South Africa, Spain, Taiwan
Hospices Civils de Lyon

Active, not recruiting

Dyslexics' Visual Attention Field

Dyslexia

France
Baxalta now part of Shire

Completed

Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor

Hemophilia A | Hemophilia B | Hemophilia A or B With Inhibitors

Poland, United States, Bulgaria, Romania, Japan, Russian Federation, New Zealand, Croatia, Ukraine, Brazil
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors (HAVEN 1)

Hemophilia A

Korea, Republic of, United States, France, Germany, Italy, South Africa, Spain, Japan, United Kingdom, Poland, Taiwan, Australia, Costa Rica, New Zealand
Ankara Training and Research Hospital

Not yet recruiting

Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent?

Kidney Stone | Ureter Obstruction | Stent Complication

Turkey
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

Hemophilia A

Taiwan
Sanofi

Recruiting

A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia (ATLAS-NEO)

Hemophilia

Greece, Korea, Republic of, France, Taiwan, Italy, Spain, United States, Canada, China, Germany, India, Japan, Mexico, South Africa, Turkey, Poland, Saudi Arabia
Kutahya Health Sciences University

Completed

Proprioception, Physical Performance, and Passing Accuracy in Adolescent Basketball Players

Basketball Players

Turkey
Changhua Christian Hospital

Withdrawn

The Efficacy and Safety of Traditional Chinese Medicine (TCM) to the Patient With Dizziness in Emergency Department

Dizziness
Ankara Yildirim Beyazıt University

Not yet recruiting

The Relationship Between Heart Rate Variation and Athletic Performance in Basketball Players

Athletic Performance | Heart Rate Variability

Turkey
Centre Hospitalier Sud Francilien
Centre National de Ressources de lutte contre la Douleur

Completed

Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology (DOLATSONG)

Pain Score

France
West China Hospital

Unknown

Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Patients

Delirium | Complication | Mechanical Ventilation

China
EMS

Withdrawn

Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension (ATENAS)

Type II Diabetes Mellitus | Hypertension Associated
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

Effects of Exercise Versus Topical Agents on Knee Osteoarthritis

Osteo Arthritis Knee

Turkey
Fudan University

Unknown

Albumin-Bound Paclitaxel Followed by Epirubicin in Combination With Cyclophosphamide in Triple Negative Breast Cancer

Triple Negative Breast Cancer

China
Fuzhou General Hospital

Not yet recruiting

ctDNA as a Biomarker for Treatment in Advanced NSCLC

Non-small Cell Lung Cancer

China
Ain Shams University

Completed

A Clinical Study for the Effect of 4th Generation Poly AmidoAmine Dendrimer on Post-Bleaching Hypersensitivity and Shade Stability

Tooth Hypersensitivity

Egypt
Universita di Verona

Completed

A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis

Peri-implant Mucositis

Italy
Samsung Medical Center

Withdrawn

Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease

Pulmonary Non-tuberculous Mycobacterial Lung Disease

Korea, Republic of
Oblato, Inc.

Withdrawn

Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participants

Glioblastoma | Astrocytoma | Oligodendroglioma
Centre hospitalier de l'Université de Montréal...

Recruiting

Attribution of Toxicities Due to Radiotherapy and Immuno-Biological Therapies (AtTRIBut)

Cancer | Radiotherapy Side Effect

Canada
Pakistan Institute of Medical Sciences

Completed

Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity

Carious Lesion

Pakistan
Pfizer

Completed

Phase 1 Study To Evaluate Antiviral Activity Of Small Molecule Direct Antiviral Agent At Multiple Doses In Subjects With Chronically Infected Hepatitis C Virus.

Hepatitis, Chronic | Hepatitis C Virus

United States
Centre Hospitalier Universitaire de Nice

Completed

Treatment of Bullous Pemphigoid With Avdoralimab (IPH5401), an Anti-C5aR1 Monoclonal Antibody (IPH)

Bullous Pemphigoid

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Active, not recruiting

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
University of Louisville
Healthpoint

Completed

Comparison of Wound Bed Establishment in Facial Burns

Burns

United States
University of Virginia

Unknown

Evaluation of Renal Blood Flow Using Contrast Enhanced Ultrasound for Differential Diagnosis of Acute Kidney Injury in Cirrhotic Patients: A Pilot Study

Liver Cirrhosis and Acute Kidney Injury

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Effects of Adding Triamcinolone Acetonide to Conbercept Treatment for Refractory Diabetic Macular Edema (CONTE) (CONTE)

Diabetes Mellitus, Type 2 | Macular Edema

China
Yonsei University

Unknown

Yonsei OCT (Optical Coherence Tomography) Registry for Evaluation of Efficacy and Safety of Coronary Stenting

Coronary Artery Disease | Ischemic Heart Disease

Korea, Republic of
Boehringer Ingelheim

Completed

Tolerability and Potential ECG Effects After a Single Oral Dose of Pentoxyverine Citrate in Healthy Male and Female Volunteers

Healthy
Tamil Nadu Dr.M.G.R.Medical University

Recruiting

Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite

Sensitivity, Tooth

India
Institute of Tropical Medicine, Belgium
Drugs for Neglected Diseases; Medecins Sans Frontieres, Netherlands; Addis Ababa... and other collaborators

Completed

Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study

HIV-infection/Aids | Visceral Leishmaniosis

Ethiopia
Sinomed Neurovita Technology Inc.

Recruiting

A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China

Intracranial Arteriosclerosis | Drug-Eluting Stents | Intracranial Artery Stenosis | Stenosis Artery

China
The First Affiliated Hospital of Zhengzhou University

Recruiting

Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer

Metastatic Colorectal Cancer

China
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); University of Sao Paulo; World... and other collaborators

Completed

BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease (BENEFIT)

Heart Disease | Chagas Disease | Trypanosomiasis

Argentina, Bolivia, Brazil, Colombia, El Salvador
Royal College of Surgeons, Ireland
New York University; The Charitable Infirmary Charitable Trust

Not yet recruiting

This is a 6-month Observational Study. Patients Included Will be Those Referred With a Possible Diagnosis or an Established Diagnosis of Asthma. It Will Look at the Association of the Asthma Microbiome and Disease Characteristics, Severity and Treatment Response.

Asthma
Zhejiang Genfleet Therapeutics Co., Ltd.

Recruiting

A Study of GFH925 in Combination With Cetuximab in Previously Untreated Advanced NSCLC Harboring KRAS G12C Mutation

Advance Non-small Cell Lung Cancer

Spain, Italy, Greece
Balgrist University Hospital

Recruiting

Short Against Long Antibiotic Therapy for Infected Orthopedic Sites (SALATIO)

Antibiotic Side Effect | Infection, Surgical Site | Orthopedic Devices Associated With Misadventures

Switzerland
SOTIO Biotech AG

Active, not recruiting

A Study of Nanrilkefusp Alfa (SOT101) in Combination With Cetuximab to Evaluate the Efficacy and Safety in Patients With Colorectal Cancer

Colorectal Cancer

France, Spain, Belgium
Tongji Hospital

Unknown

A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIP Study)

End Stage Liver Disease | Infection | Spontaneous Bacterial Peritonitis

China
University of Sao Paulo

Recruiting

Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND) (DREAMLAND)

Endometriosis | Pelvic Pain

Brazil
Nova Scotia Health Authority

Terminated

Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery

Cataract | Mydriasis | Phacoemulsification | Pseudoexfoliation Syndrome

Canada
Scientific Institute San Raffaele

Unknown

Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI) (TRIDUAL-PCI)

Myocardial Infarction | Coronary Disease | Atrial Fibrillation | Anticoagulant-induced Bleeding

Italy
R&D Cardiologie
Biotronik SE & Co. KG

Unknown

Hybrid Sirolimus-eluting Versus Everolimus-eluting Stents for Total Coronary Occlusions (PRISON-IV)

Coronary Artery Disease | Coronary Disease | Coronary Stenosis

Netherlands, Belgium
I.R.C.C.S. Fondazione Santa Lucia

Completed

Dopaminergic Modulation of Declarative Memory

Parkinson's Disease

Italy
Hepatopancreatobiliary Surgery Institute of Gansu...

Recruiting

Photodynamic Therapy for Cholangiocarcinoma

Cholangiocarcinoma Non-resectable

China
Tongji Hospital

Unknown

A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIR Study)

End Stage Liver Disease | Infection

China
Biogen

Completed

A Study of BIIB022 in Combination With Paclitaxel and Carboplatin in Subjects With Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States

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