Search clinical trials for: CYP and transporter probe substrates

Total 14158 results

ViiV Healthcare

Completed

Study on Effects of BMS-955176 on the Pharmacokinetics of Probe Substrates

HIV Infections

United States
Celgene

Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Eosinophilic Esophagitis

United States
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Emalex Biosciences Inc.
ICON Early Phase Services; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates for Drug Metabolism and Transport

Drug Interaction

United States
University of Aarhus
Danish Heart Foundation

Completed

Modulation of Free Fatty Acids in Heart Failure Patients With Diabetes: "Effect on Left Ventricular Function" (Metamod3)

Heart Failure | Diabetes

Denmark
Galderma R&D

Completed

A Study to Assess the Effects of Nemolizumab on Cytochrome P450 Substrates in Participants With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

United States, Bulgaria
Mahidol University

Recruiting

Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers

Gastroduodenal Ulcer

Thailand
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children

Child

United Kingdom
Misr International University

Recruiting

Assessment of Gingival Thickness Using Colored Periodontal Probe

Gingival Phenotype

Egypt
Advanced Perfusion Diagnostics
CEISO

Completed

Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation (MC Monitor)

Multiple Organ Dysfunction Syndrome

France
University of North Carolina, Chapel Hill
Appalachian State University

Completed

Impact of Black Pepper on Energy Expenditure and Substrate Utilization

Obesity

United States
Parc de Salut Mar

Completed

Improvement of Transient Elastography Applicability and Diagnostic Accuracy to Identify Significant Fibrosis by Experienced Operators Using the M and XL Probe.

Chronic Liver Diseases (CLD)

Spain
Washington University School of Medicine

Active, not recruiting

Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps

Rectal Cancer | Colon Cancer | Cancer of the Colon | Cancer of the Rectum | Precancerous Polyp | Malignant Polyp

United States
AbbVie

Completed

A Study to Evaluate the Effect of Intravenous (IV) Infusions of Risankizumab on Pharmacokinetics of Cytochome P450 Substrates in Adult Participants With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis (UC)

United States, Germany, Israel
Medical University of Graz

Completed

Effect of Thoracic Diameter and Food Intake on Fibroscan® Results (FS)

Liver Stiffness

Austria
Washington University School of Medicine
National Cancer Institute (NCI)

Recruiting

Diagnostic US for Reduction of Benign Breast Biopsies Using US-guided Optical Tomography

Breast Biopsy

United States
NeMoDevices AG
Medical University of Graz; University of Zurich

Completed

A New Multi-parameter Neuromonitoring System to Save Patients' Lives in Stroke and Brain Injury

Subarachnoid Hemorrhage | Optical Imaging

Austria, Switzerland
IHU Strasbourg

Terminated

Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology (TRaMA)

Rectal Cancer | Rectal Adenocarcinoma

France
University of Pennsylvania
National Institutes of Health (NIH)

Enrolling by invitation

Intraoperative Echocardiography in Low-Risk CABG Surgery

Heart Diseases | Coronary Artery Disease | Chest Pain | STEMI | Stenosis Coronary

United States
Yonsei University

Recruiting

Intraoperative Body Temperature Measurement Using Infrared Camera: Comparison With Esophageal, and Skin Temperatures

Patients Undergoing General Anesthesia

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral Bronchoscopy

Lung Neoplasm | Malignant Neoplasms of Respiratory and Intrathoracic Organs

United States
University of California, Los Angeles

Recruiting

TEST-ON - Does iStim Reduce Urinary Urgency? (TEST-ON)

Overactive Bladder | Urgency-frequency Syndrome | Urinary Frequency More Than Once at Night

United States
University Ghent
University of Amsterdam; PZ Heilig Hart; PZ Sint-Camillus

Completed

Research on the Efficacy of the "T.O.P. Computer Training" Procedure in the Treatment of Alcohol Dependence

Alcohol Dependence

Belgium
Washington University School of Medicine

Terminated

Ultrasound and Photoacoustic Imaging for Cervical Cancer

Cervical Cancer | Cancer of the Cervix

United States
Fox Chase Cancer Center

Terminated

VM110 in Detection of Microscopic Tumors: A Phase I Study

Pancreatic Cancer | Ovarian Cancer

United States
Hospital Universitari Vall d'Hebron Research Institute

Completed

Biological Response to Meal Ingestion: Gender Differences

Healthy

Spain
Vanderbilt University Medical Center
Alcon Research

Completed

Beveled-Tip Versus(vs) Standard-Tip Vitrectomy Probe

Vitrectomy

United States
Ottawa Heart Institute Research Corporation
University of British Columbia; McGill University

Not yet recruiting

Patient Specific Ablation Strategy for Atrial Fibrillation (AWARE-2): A Randomized Clinical Trial (AWARE-2)

Atrial Fibrillation | Radiofrequency Catheter Ablation | Catheter Ablation

Canada
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Substrate Guided Ablation Therapy for Atrial Fibrillation (HEAT-AF)

Persistent Atrial Fibrillation
Stanford University

Withdrawn

Photoacoustic Imaging (PAI) of Suspicious Breast Cancers - A Clinical Feasibility Study

Breast Cancer
University of Arkansas
Radiation Monitoring Devices, Inc.

Withdrawn

Intraoperative Imaging of a PET Positive Lymph Node(s) Using 18FDG and a Dual-Mode, Hand-Held Intraoperative Imager

Head and Neck Neoplasms

United States
University of California, San Diego

Completed

Transcranial Doppler Using Wearable Ultrasound Patch (TCD)

Stroke | Brain Diseases | Brain Injuries | Vasospasm | Medical Device Complication

United States
Vanderbilt University Medical Center

Completed

Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux Disease (ADHERE)

GERD | Larynx Disease

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Johns Hopkins University

Completed

Evaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer

Suspected Primary Prostate Cancer

United States
Hospital Universitari Vall d'Hebron Research Institute

Completed

Responses to a Comfort Meal in Functional Dyspepsia

Functional Gastrointestinal Disorders

Spain
Beth Israel Deaconess Medical Center
MedWaves, Inc

Recruiting

Feasibility of the AveCure Microwave Ablation Technology for the Bronchoscopic Treatment of Malignant Central Airway Obstructions

Airway Obstruction | Central Airway Obstruction

United States
Stanford University

Completed

Photoacoustic Imaging (PAI) of the Prostate: A Clinical Feasibility Study

Prostate Cancer

United States
Gangnam Severance Hospital

Not yet recruiting

Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block

Cervical Spinal Stenosis

Korea, Republic of
Indiana University
IntraMedical Imaging, LLC

Completed

Ex-vivo Investigation of Beta Probe for Prostate Cancer Resection and Evaluation of PSMA-PET for Diagnosis of Intraprostatic Lesions

Prostate Cancer

United States
University of Oklahoma

Recruiting

Use of Endobronchial Ultrasound Scope (EBUS) Transducer to Identify Pneumothorax-A Feasibility Study

Pneumothorax

United States
Injeq Ltd

Completed

Use of BIP-Needles in Rheumatologic Injections

Intra-articular Injections

Finland
University of Eastern Finland
Kuopio University Hospital; Finnish Cultural Foundation; Academy of Finland; Diabetes...

Completed

Effects of LRYGB on Pharmacokinetics of Nine CYP Probe Drugs

Obesity, Morbid | Bariatric Surgery Candidate

Finland
Hospital Vall d'Hebron

Completed

The Use of the Transient Elastography Paediatric Probe, Compared to the M Probe, Indirect Biomarkers and Histology

Fibrosis, Liver | Elastography | Chronic Liver Disease | Pediatrics

Spain
Massachusetts General Hospital

Active, not recruiting

Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

Inflammatory Bowel Diseases | Crohn Disease | Permeability; Increased | Inflammatory Disease | Environmental Enteropathy

United States
University of Nottingham
University Hospitals of Derby and Burton NHS Foundation Trust

Completed

A Study of Agreement Between Oxygen Saturation Measured by Two Probes in Infants on the Neonatal Unit (Ag-OS)

Neonatal Disease

United Kingdom
Hadassah Medical Organization

Unknown

Comparison of Safety And Efficacy of Neuraxial Anesthesia, Palpation Versus Ultrasound

Regional Anesthesia

Israel
Cairo University

Unknown

Recanalization of Congenital Nasolacrimal Duct Obstruction by Endodiathermy Probe and Intubation Versus Intubation Only

Congenital Nasolacrimal Duct Obstruction

Egypt
Eman Zakaria Ali Hashem

Unknown

Prevalence of MIH Among Group of Egyptians Children Aged From 8 to 12 in Damietta

Molar Incisor Hypomineralization
University of Texas Southwestern Medical Center

Completed

Optimal Positioning of Nasopharyngeal Temp Probe

Pediatric Temperature

United States
Istanbul University - Cerrahpasa (IUC)

Recruiting

The Effect of Position Given to Preterms After Feeding on Gastric Residual Volume, Abdominal Oxygenation and Fractional Oxygen Extraction

Gastric Residual Volume | Abdominal Oxygenation | Fractional Oxygen Extraction | Positioning (Prone, Right Lateral and Semi-Elevated Supine Position)

Turkey

Search clinical trials for: CYP and transporter probe substrates

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