Search clinical trials for: DFD01 Spray

Total 925 results

Advanced Ophthalmic Pharma

Completed

Bioequivalence of Eye Drops and Spray Administration of Vigamox

Cataract

Israel
Alcon Research

Completed

Safety and Efficacy of Olopatadine HCl Nasal Spray in 6-11 Year Old Patients

Seasonal Allergic Rhinitis

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Early Immunotherapy With Intravenous Immunoglobulin, Cyclophosphamide and Methylprednisolone in Patients With Anti-Hu-associated Paraneoplastic Sensory Neuronopathy (NESPA)

Paraneoplastic Sensory Neuronopathy

France
Assaf-Harofeh Medical Center

Recruiting

Gonadotropin Releasing Hormone Agonist (GnRHa) Versus Estrogen and Progesterone for Luteal Support in High Responders

Ovarian Hyperstimulation Syndrome | Miscarriage | Pregnancy Early

Israel
Cairo University
Algazeerah hospital

Completed

Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion

Contraception

Egypt
All India Institute of Medical Sciences, New Delhi

Completed

Transcricoid Injection vs. Spray as You go Method for Local Anaesthesia During EBUS-TBNA (CRISPEN)

Pulmonary Disease

India
Lumbini Medical College

Completed

Efficacy and Cost Analysis of Steroids in Treatment of Otitis Media With Effusion

Otitis Media With Effusion

Nepal
Marina Ramsis Aziz Ghaly

Recruiting

Lidocaine Spray 10% Versus Oral Ibuprofen Tablets in Pain Control During Copper Intrauterine Device Insertion

Lidocaine Toxicity

Egypt
Nanhua University
Buddhist Tzu Chi General Hospital; Solano Semiconductor Technology., LTD.

Completed

Effect of Health Promotion on Allergic Rhinitis by Infrared-C Ray Irradiation

Allergic Rhinitis
INSYS Therapeutics Inc

Withdrawn

Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain

Acute Pain

United States
Karlstad University

Completed

Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding

Mastitis

Sweden
Synmosa Biopharma Corp.

Completed

A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergic Rhinitis

Allergic Rhinitis

Taiwan
Allergan

Completed

Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease

Dry Eye Syndromes

United States
Acorda Therapeutics

Terminated

Bioavailability, Safety and Tolerability of Diazepam Nasal Spray Versus Diazepam Rectal Gel (Diastat®)

Refractory Epilepsy

United States
University of Washington
GlaxoSmithKline

Recruiting

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic... and other conditions

United States
Augusta University
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Nitric Oxide Bioavailability and Early Life Stress (NO-Stress) (NO-Stress)

Cardiovascular Disease

United States
University of Chicago

Unknown

Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis

Allergic Rhinitis

United States
Medical University of Vienna
Croma-Pharma GmbH

Completed

Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses

Dry Eye Syndrome

Austria
Eyenovia Inc.

Completed

Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation

Mydriasis

United States
Virginia Commonwealth University

Withdrawn

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General

Apical Periodontitis | Caries,Dental
Ostfold Hospital Trust

Unknown

Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics

Intubation Complication

Norway
Virginia Commonwealth University

Terminated

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric

Apical Periodontitis | Caries,Dental

United States
Virginia Commonwealth University

Withdrawn

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics

Apical Periodontitis | Caries,Dental
Shiraz University of Medical Sciences

Completed

Evaluation of Pressure Sense Threshold and Tactile Sensation After Lidocaine Iontophoresis Using Interferential Current

Interferential Current Drug Delivery

Iran, Islamic Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Malignant Solid Neoplasm | Melanoma | Colitis | Lung Non-Small Cell Carcinoma | Malignant Genitourinary System Neoplasm

United States
M.D. Anderson Cancer Center

Recruiting

Durvalumab and Tremelimumab in Treating Participants With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma | Refractory Fallopian Tube... and other conditions

United States
University of North Carolina, Chapel Hill

Withdrawn

Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment

Local Anesthesia | Endodontic Disease | Endodontic Inflammation | Dental Anesthesia
Hadassah Medical Organization

Completed

Bioequivalence Assessment of Oral Administration Vs. Oral Spray of a Cannabinoids (Tetrahydrocannabinol and Cannabidiol)

Pain

Israel
Bayer
Queen's University

Completed

A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis (GEYSER)

Seasonal Allergic Rhinitis

Canada
Hams Hamed Abdelrahman

Unknown

Topical Chamomile in Preventing Chemotherapy-induced Oral Mucositis

Oral Mucositis Due to Chemotherapy

Egypt
St. Renatus, LLC
Rho, Inc.; Ground Zero Pharmaceuticals

Completed

Dose-Escalation Safety and Pharmacokinetic Study of K305

Anesthesia

United States
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
St. Renatus, LLC
Rho, Inc.; Triligent International; Analytical Bio-Chemistry Laboratories, Inc.

Completed

Safety and Pharmacokinetics of Kovacaine Nasal Spray (24 Hour Blood Collection)

Anesthesia

United States
University of Reading
GlaxoSmithKline

Completed

Anthocyanin-rich Blackcurrant and Vascular Function

Inflammation | Vascular Stiffness

United Kingdom
University Hospital, Basel, Switzerland

Completed

Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia

Conscious Sedation

Switzerland
Princess Maxima Center for Pediatric Oncology
Innovative Therapies For Children with Cancer Consortium; IBFM; Fight Kids Cancer

Not yet recruiting

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies (HEM-iSMART D)

Acute Lymphoblastic Leukemia, in Relapse | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent | Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory | Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Netherlands
Lawson Health Research Institute

Recruiting

Anxiolysis for Laceration Repair in Children (ALICE)

Distress, Emotional | Laceration of Skin

Canada
Tayside Medical Science Centre

Withdrawn

Ethyl Chloride Spray Versus Subcutaneous Lidocaine Anaesthetic Prior to Contraceptive Implant Insertion

Contraception
Institute of Liver and Biliary Sciences, India

Completed

Sedation for Patients Undergoing Endoscopic Retrograde Cholangiopancreatography

Biliary Colic

India
St. Renatus, LLC

Completed

Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers

Anesthesia

United States
Meissa Vaccines, Inc.

Recruiting

Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults

Covid19

United States
Hams Hamed Abdelrahman

Unknown

Vitamin D Oral Gel for Prevention of Radiation Induced Oral Mucositis

Oral Mucositis Due to Radiation

Egypt
Yale University
National Cancer Institute (NCI)

Active, not recruiting

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV (SMARTTT)

Tobacco Use Cessation

United States
Daniel Merenstein
Patient-Centered Outcomes Research Institute; University of California, Los... and other collaborators

Active, not recruiting

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis - Pilot (NOSES)

Sinus Infection | Acute Sinusitis

United States
Albert Einstein Healthcare Network

Terminated

Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage

Abscess

United States
Bayer

Completed

A Study to Evaluate Changes in Nasal Airflow of Loratadine/Pseudoephedrine Tablet and Fluticasone Propionate Nasal Spray in Subjects Following Allergen Exposure

Rhinitis, Allergic

Canada
Emory University
National Institute of Mental Health (NIMH); John Templeton Foundation

Completed

Biological Basis of Individual Variation in Social Cooperation

Healthy

United States
INSYS Therapeutics Inc

Completed

Pharmacokinetic Study of Fentanyl 400 µg Sublingual Spray, Actiq® 400 µg Transmucosally, and Fentanyl Citrate Injection 100 µg Intravenously (iv)

Pain

United States
M.D. Anderson Cancer Center
Allergan

Withdrawn

Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel

Epiphora
Chiesi SAS
Kappa Santé

Recruiting

Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study (TriNEXT)

COPD

France

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