Search clinical trials for: Definity®

Total 13926 results

Al B. Benson, III, MD
Celgene Corporation; Big Ten Cancer Research Consortium

Completed

FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma

Gastric Cancer | Gastro-Esophageal Junction Adenocarcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Stand Up To Cancer; Iovance Biotherapeutics, Inc.; Prometheus...

Completed

Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Adenocarcinomas | Squamous Cell Carcinoma | Advanced NSCLC | Metastatic Non-small Cell Lung Cancer | Adenosquamous Carcinoma

United States
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Completed

A Study of HyQvia and Gammagard Liquid (Kiovig) in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

United States, Israel, Canada, Spain, Czechia, Croatia, Poland, Italy, Serbia, Germany, Argentina, Mexico, Turkey, United Kingdom, Brazil, France, Greece, Slovakia, Colombia, Denmark, Norway, Sweden
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) (FAST2)

Hereditary Angioedema

Italy
Rafic Farah, MD

Completed

Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source

Lymphoma | Leukemia | Myelofibrosis | MDS

United States
University of Oxford
Oxford University Hospitals NHS Trust; Imunon

Completed

Targeted Chemotherapy Using Focused Ultrasound for Liver Tumours (TARDOX)

Liver Tumour

United Kingdom
Duke University
GlaxoSmithKline

Completed

Chemotherapy With Monoclonal Antibody and Radioimmunotherapy for High-Risk B-Cell Non-Hodgkins Lymphoma

Lymphoma, B-Cell

United States
Astellas Pharma Inc

Completed

Study to Evaluate the Effect of Multiple-dose of Fluvoxamine on the Plasma Concentration of Quetiapine (FK949E) in Healthy Male Volunteers

Healthy | Pharmacokinetics of Quetiapine

Japan
Indivior Inc.

Completed

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Hepatic Impairment | Hepatic Failure | Chronic Hepatitis C Infection With Hepatic Coma

United States
Ohio State University Comprehensive Cancer Center

Completed

Liposomal Doxorubicin, Vincristine, & Dexamethasone Plus Arsenic Trioxide in Untreated Symptomatic Multiple Myeloma

Multiple Myeloma

United States
Bayer

Completed

Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED)

Seasonal Allergic Rhinitis | Vasomotor Rhinitis
AbbVie (prior sponsor, Abbott)
Quintiles, Inc.

Completed

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

Advanced Parkinson's Disease

United States, Germany
University Hospital, Strasbourg, France
Bayer; Grünenthal GmbH; Fédération Hospitalo-Universitaire NEUROGENYCS

Recruiting

TOTEM RRMS : TestOsterone TreatmEnt on Neuroprotection and Myelin Repair in Relapsing Remitting Multiple Sclerosis (TOTEM-RRMS)

Multiple Sclerosis, Relapsing-Remitting

France
Hospital Central Norte PEMEX

Completed

Abdominal Binder in Colonoscopies Performed by Trainees

Performance of Colonoscopy | Tolerance of Colonoscopy

Mexico
MRC/UVRI and LSHTM Uganda Research Unit
King's College London; Karolinska Institutet; Gilead Sciences; Imperial College... and other collaborators

Enrolling by invitation

A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP (PrEPVacc)

HIV Infections

Uganda
Chiesi SA/NV

Completed

Fixed Dose Triple Therapy in Severe Chronic Obstructive Pulmonary Disease in a Real World Setting (TRIVOLVE)

Chronic Obstructive Pulmonary Disease

Belgium
Joint Stock Company "Farmak"

Completed

Fasted Bioequivalence Study of 2 Olanzapine Film-coated Tablets, 5 mg, in Healthy, Adult Male and Female Subjects.

Pharmacokinetics

Czechia
Lisa Haddad
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Impact of Hormonal Contraception on HIV Acquisition and Transmission Risk

HIV | Contraception

United States
Cubist Pharmaceuticals LLC

Completed

Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)

Skin Diseases, Infectious | Skin Diseases, Bacterial
Ironwood Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers

Healthy Volunteers

United States
UCB BIOSCIENCES GmbH
Eden Sarl

Completed

Evaluating Long Term Safety of Lacosamide (LCM) to Carbamazepine Controlled-release (CBZ-CR); Initial Monotherapy in Epilepsy Subjects 16 Years and Older

Epilepsy | Monotherapy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Philippines, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Swede... and more
Dexa Medica Group
PT. Equilab International

Completed

Bioequivalence Study of 120 mg Etoricoxib Film-coated Tablets

Healthy

Indonesia
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)

Type 2 Diabetes Mellitus
Alcon Research

Completed

Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration

Cataract
Life Extension Foundation Inc.

Completed

Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)

Completed

Systolic Hypertension in the Elderly Program (SHEP)

Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Hypertension
Dexa Medica Group

Completed

Bioequivalence Study of Two Formulations of 10 mg Lisinopril Tablet Under Fasting Condition

Healthy

Indonesia
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

A Study Evaluating Desvenlafaxine Sustained Release (DVS SR) in Adult Female Outpatients With Fibromyalgia

Fibromyalgia

United States
Pfizer

Completed

A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.

Candidiasis
Actavis Inc.

Completed

A Relative Bioavailability Study of Mirtazapine 15 mg Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Mirtazapine 15 mg Tablets Under Non-fasting Conditions

Healthy

United States
University of Miami

Recruiting

Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma

Adult T-cell Leukemia-Lymphoma | ATLL

United States
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
DSM Nutritional Products, Inc.

Completed

Dermal Irritation, Sensitization and Cumulative Irritation Potential of 6% Bemotrizinol

Sunburn

United States
Pharbil Waltrop GmbH

Completed

Bioavailability Study With Oral Single Dose Administration of Ethinylestradiol and Dienogest

Focus: Bioequivalence

Germany
Hoffmann-La Roche

Completed

An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN)

Colorectal Cancer

United Kingdom
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Teva Branded Pharmaceutical Products R&D, Inc.
PPD

Completed

A Study of the Effectiveness and Safety of Different Doses of Fluticasone Propionate Taken From a Dry Powder Inhaler in Adolescents and Adults Who Have Asthma That is Not Controlled by Asthma Medications Not Containing Steroids

Asthma

United States, Bulgaria, Croatia, Hungary, Israel, Poland, Serbia, Spain, Ukraine
Democritus University of Thrace

Completed

Monovision vs Multifocal Lens Insertion in Cataract Patients

Cataract

Greece
Bayer

Completed

Effects of Phenylephrine Extended-Release Tablets on Allergy-Related Nasal Congestion (P08498 AM1)

Seasonal Allergic Rhinitis
AbbVie (prior sponsor, Abbott)
Quintiles, Inc.

Completed

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

Advanced Parkinson's Disease

United States, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Cancer

United States, Australia
Alcon Research

Completed

Circadian Ocular Perfusion Pressure and Ocular Blood Flow

Glaucoma

United States
Sanofi

Completed

Nasacort AQ Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Children With Allergic Rhinitis

Rhinitis, Allergic, Perennial and/or Seasonal

United States
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)

Urinary Bladder Neoplasms

United States, Australia, Czechia, Estonia, France, Guatemala, Hungary, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Poland, Portugal, Puerto Rico, Romania, Spain, Taiwan, Turkey, Ukraine, United Kingdom, Denmark, ... and more
Yonsei University

Recruiting

Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

Acute Coronary Syndrome

Korea, Republic of
University Hospital, Lille
National Research Agency, France

Active, not recruiting

Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS) (MRI-PCOS)

Polycystic Ovary Syndrome

France
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
Hospital Universitari Vall d'Hebron Research Institute

Completed

Remifentanil Effect-site Prediction by Algometry

Conscious Sedation Failure During Procedure

Spain

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