Search clinical trials for: Dextromethophan

Total 142 results

Montefiore Medical Center

Completed

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Cough Reflex Sensitivity

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Dextromethorphan Syrup in Comparison to Dextromethorphan Soft Pastilles in Healthy Male and Female Subjects

Healthy
Boehringer Ingelheim

Completed

Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects

Healthy
Pfizer

Completed

A Pharmacokinetic (PK) Study Of PF-00299804 And Dextromethorphan In Healthy Volunteers

Healthy Volunteers

Belgium
National Institute of Neurological Disorders and...

Completed

Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous System

Parkinson's Disease | Neurodegenerative Disease

United States
National Institute of Dental and Craniofacial Research...

Completed

Dextromethorphan Versus Placebo for Neuropathic Pain

Diabetic Neuropathies | Neuralgia | Herpes Zoster

United States
Hugo W. Moser Research Institute at Kennedy Krieger...
The Johns Hopkins Institute for Clinical and Translational Research (ICTR)

Completed

Placebo Controlled Trial of Dextromethorphan in Rett Syndrome (PCTDMRTT)

Rett Syndrome

United States
National Institute on Drug Abuse (NIDA)

Unknown

Hyperalgesia in Methadone Patients: Can it be Treated?

Opioid-induced Hyperalgesia

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Dextromethorphan in Treating Patients With Fatigue Caused by Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Fatigue | Unspecified Adult Solid Tumor, Protocol Specific

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan

Alzheimer Disease | Huntington Disease

United States
Medical University of South Carolina

Completed

A Trial of Dextromethorphan for Treatment of Major Depressive Disorder

Major Depressive Disorder
Nathanael Heckmann

Recruiting

Dextromethorphan for Treatment of Postoperative Pain

Post-operative Pain

United States
University Hospital, Geneva
Jules Desmeules; Youssef Daali; Kenza Abouir; Eduardo Schiffer; Bernard Walder

Recruiting

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol (PREDICT)

Pain | Interaction

Switzerland
Profil Institut für Stoffwechselforschung GmbH
Heinrich-Heine University, Duesseldorf

Completed

Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects (DXM/AMT)

Type 2 Diabetes Mellitus

Germany
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Dextromethorphan for Diabetic Macular Edema (MiDME2)

Diabetic Macular Edema

United States
Taichung Veterans General Hospital
TSH Biopharm Corporation Limited

Completed

Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis

Rheumatoid Arthritis
National Cheng-Kung University Hospital
National Health Research Institutes, Taiwan; TTY Biopharm

Completed

Add-on Dextromethorphan in Bipolar Disorders (DM)

Bipolar Disorder

Taiwan
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

Effects of Isotretinoin on CYP2D6 Activity

CYP2D6 Polymorphism

United States
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)

Schizophrenia
Duke University
North Carolina Translational and Clinical Sciences Institute

Withdrawn

Cortical Metrics in Intervention Trials With Autism Spectrum Disorders

Autism Spectrum Disorders

United States
Avanir Pharmaceuticals

Completed

A Phase 1 Study Comparing AVP-786 With AVP-923

Healthy Volunteer

United States
Dr. Rachel Rooney

Completed

Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?

Pain, Postoperative
National Cheng-Kung University Hospital

Unknown

Combination of Dextromethorphan and Memantine in Treating Bipolar Disorder

Bipolar Disorder II

Taiwan
Galera Therapeutics, Inc.

Completed

Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult Subjects

Healthy

United States
Pfizer

Terminated

Dextromethorphan Pediatric Acute Cough Study (CHPA DXM)

Cough

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Dextromethorphan

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome

Rett Syndrome

United States
Eunice Kennedy Shriver National Institute of Child...
Johns Hopkins University

Completed

Study of the Pathogenesis of Rett Syndrome

Rett Syndrome
National Cheng-Kung University Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction

Amphetamine Addiction | Pharmacotherapy

Taiwan
University of Louisville
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

rhGH Therapy on Hepatic Drug Metabolism

Growth Hormone Deficiency, Dwarfism

United States
Tzu-Yun Wang
Ministry of Science and Technology, Taiwan

Completed

Add-on Low Dose Dextromethorphan and Memantine in Patients With Amphetamine-type Stimulants Use Disorder

Stimulants Use Disorder

Taiwan
NCIC Clinical Trials Group

Completed

Treatment for Chronic Pain in Patients With Advanced Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

Canada
Children's Mercy Hospital Kansas City
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body

Healthy

United States
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Assessing the Pharmacokinetics and Drug Interaction Liability of Kratom, an Opioid-like Natural Product

Interaction Drug Food

United States
Brigham and Women's Hospital
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial

Spinal Cord Injury | Allodynia | Central Neuropathic Pain

United States
Genentech, Inc.

Completed

Study of Cobimetinib in Participants With Solid Tumors

Solid Tumor

United States
GlaxoSmithKline

Completed

To Investigate the Gastrointestinal Behaviour of Two Triple Combination Products in Healthy Male Volunteers

Common Cold

United States
University Hospital, Clermont-Ferrand
Dr Malou Navez, Pain Clinic, Saint-Etienne Hopital; Dr Marc Sorel, Pain Clinic... and other collaborators

Completed

Study of NMDA Antagonists and Neuropathic Pain (NMDA)

Neuropathic Pain

France
Aegerion Pharmaceuticals, Inc.

Completed

Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents

Healthy

United States
Axsome Therapeutics, Inc.

Completed

Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)

Major Depressive Disorder | Treatment Resistant Depression

United States
Study Investigator-Sponsor
Society of Family Planning

Completed

Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion (DexMab)

Abortion in First Trimester

United States
Pfizer
Novartis; Boehringer Ingelheim; Reckitt Benckiser LLC; Procter and Gamble; Perrigo... and other collaborators

Terminated

Acute Cough Study In Children

Common Cold | Infections, Upper Respiratory Tract

United States
Daiichi Sankyo, Inc.

Completed

Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Jules Desmeules

Completed

Endobiotics for Phenotyping of Human Cytochrome P450 Enzymes (ENDOCYP2D6)

Healthy

Switzerland
University of Colorado, Denver
National Institute of General Medical Sciences (NIGMS)

Terminated

Pharmacogenetic Prediction of Metoprolol Effectiveness

Hypertension

United States
National Institute of Dental and Craniofacial Research...

Completed

Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain

Pain | Facial Neuralgia | Trigeminal Neuralgia

United States
Cognition Therapeutics

Completed

Drug Interaction Study of CT1812 in Healthy Volunteers

Healthy Volunteers

United States
Johns Hopkins University

Completed

Three Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive Disorder

Smoking | Smoking Cessation | Treatment Resistant Depression | MDD

United States
University of Alabama at Birmingham

Completed

Dextromethorphan in Fibromyalgia

Fibromyalgia

United States
Hugo W. Moser Research Institute at Kennedy Krieger...

Terminated

Trial of Dextromethorphan in Rett Syndrome

Rett Syndrome

United States

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