Search clinical trials for: Dextromethorphan hydrobromide

Total 203 results

Medical University of South Carolina

Completed

A Trial of Dextromethorphan for Treatment of Major Depressive Disorder

Major Depressive Disorder
Nathanael Heckmann

Recruiting

Dextromethorphan for Treatment of Postoperative Pain

Post-operative Pain

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Dextromethorphan in Treating Patients With Fatigue Caused by Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Fatigue | Unspecified Adult Solid Tumor, Protocol Specific

United States
National Eye Institute (NEI)
The Emmes Company, LLC

Completed

Dextromethorphan for Diabetic Macular Edema (MiDME2)

Diabetic Macular Edema

United States
Taichung Veterans General Hospital
TSH Biopharm Corporation Limited

Completed

Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis

Rheumatoid Arthritis
Vigonvita Life Sciences

Completed

A Study to Evaluate the Bioavailability, Food Effect and Pharmacokinetics of Deuremidevir Hydrobromide for Suspension

Healthy Subjects

China
Pfizer

Terminated

Dextromethorphan Pediatric Acute Cough Study (CHPA DXM)

Cough

United States
Dr. Rachel Rooney

Completed

Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?

Pain, Postoperative
Hartford Hospital
Spero Therapeutics

Completed

Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis

Diabetes | ABSSSI | Healthy Volunteers | Wound Infection

United States
Vigonvita Life Sciences

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral Deuremidevir Hydrobromide for Suspension

Respiratory Syncytial Virus Infections

China
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Healthy Subjects | Subjects With Renal Impairment

China
Spero Therapeutics

Completed

Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Montefiore Medical Center

Completed

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Cough Reflex Sensitivity

United States
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Elderly Chinese Subjects With Underlying Diseases

Elderly Subjects With Underlying Diseases

China
NCIC Clinical Trials Group

Completed

Treatment for Chronic Pain in Patients With Advanced Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

Canada
Profil Institut für Stoffwechselforschung GmbH
Heinrich-Heine University, Duesseldorf

Completed

Dextromethorphan, Amantadine and Glucose Homeostasis in Diabetes Subjects (DXM/AMT)

Type 2 Diabetes Mellitus

Germany
Vigonvita Life Sciences

Recruiting

A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV

Respiratory Syncytial Virus Infection

China
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Subjects With Liver Function Injury | Normal Liver Function Subject

China
Boehringer Ingelheim

Completed

Relative Bioavailability of Dextromethorphan Syrup in Comparison to Dextromethorphan Soft Pastilles in Healthy Male and Female Subjects

Healthy
Spero Therapeutics

Completed

Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degrees Of Renal Function

Renal Impairment

United States
Avanir Pharmaceuticals
Syneos Health

Completed

Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS (STAR)

Pseudobulbar Affect (PBA)

United States, Argentina, Brazil
Study Investigator-Sponsor
Society of Family Planning

Completed

Dextromethorphan as a Novel Non-opioid Adjunctive Agent for Pain Control in Medication Abortion (DexMab)

Abortion in First Trimester

United States
Boehringer Ingelheim

Completed

Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects

Healthy
Pfizer

Completed

A Pharmacokinetic (PK) Study Of PF-00299804 And Dextromethorphan In Healthy Volunteers

Healthy Volunteers

Belgium
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer

Breast Cancer

United States
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Avanir Pharmaceuticals

Completed

Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants

Healthy Adult Male and Female Volunteers

United States
Avanir Pharmaceuticals

Terminated

Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)

Pseudobulbar Affect (Involuntary Laughing and/or Crying)

United States
Sutter Health

Completed

Nuedexta for the Treatment of Adults With Autism (Nuedexta)

Autism

United States
National Institute of Neurological Disorders and...

Completed

Dextromethorphan for the Treatment of Parkinson's Disease and Similar Conditions of the Nervous System

Parkinson's Disease | Neurodegenerative Disease

United States
National Institute of Dental and Craniofacial Research...

Completed

Dextromethorphan Versus Placebo for Neuropathic Pain

Diabetic Neuropathies | Neuralgia | Herpes Zoster

United States
Hugo W. Moser Research Institute at Kennedy Krieger...
The Johns Hopkins Institute for Clinical and Translational Research (ICTR)

Completed

Placebo Controlled Trial of Dextromethorphan in Rett Syndrome (PCTDMRTT)

Rett Syndrome

United States
National Institute on Drug Abuse (NIDA)

Unknown

Hyperalgesia in Methadone Patients: Can it be Treated?

Opioid-induced Hyperalgesia

United States
Center for Neurologic Study, La Jolla, California,
State University of New York - Upstate Medical University; ALS Association

Completed

Clinical Trial Nuedexta in Subjects With ALS

Amyotrophic Lateral Sclerosis (ALS)

United States
Handok Inc.

Recruiting

Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin (TERA 305)

Type 2 Diabetes

Korea, Republic of
Pfizer
Medivation, Inc.

Completed

A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan

Alzheimer Disease | Huntington Disease

United States
Handok Inc.

Recruiting

Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin (TERA 304)

Type 2 Diabetes

Korea, Republic of
Janssen Research & Development, LLC

Completed

A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

United States, Canada
University Hospital, Geneva
Jules Desmeules; Youssef Daali; Kenza Abouir; Eduardo Schiffer; Bernard Walder

Recruiting

Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol (PREDICT)

Pain | Interaction

Switzerland
Avanir Pharmaceuticals

Completed

Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Depressive Disorder, Treatment-Resistant

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine (ATEM)

Migraine Without Aura | Migraine With Aura

China
National Cheng-Kung University Hospital
National Health Research Institutes, Taiwan; TTY Biopharm

Completed

Add-on Dextromethorphan in Bipolar Disorders (DM)

Bipolar Disorder

Taiwan
University of Washington
National Institute of General Medical Sciences (NIGMS)

Completed

Effects of Isotretinoin on CYP2D6 Activity

CYP2D6 Polymorphism

United States
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)

Schizophrenia
Avanir Pharmaceuticals

Completed

A Phase 1 Study Comparing AVP-786 With AVP-923

Healthy Volunteer

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Dextromethorphan

United States
National Cheng-Kung University Hospital

Unknown

Combination of Dextromethorphan and Memantine in Treating Bipolar Disorder

Bipolar Disorder II

Taiwan
Galera Therapeutics, Inc.

Completed

Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult Subjects

Healthy

United States
Washington University School of Medicine
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Treatment of Acute Sinusitis

Acute Respiratory Infections | Acute Rhinosinusitis

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome

Rett Syndrome

United States

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