Search clinical trials for: Dipeptidyl peptidase 4 (DPP 4) inhibitor

Total 2581 results

AstraZeneca
Bristol-Myers Squibb

Completed

Treatment Effect of Saxagliptin Compared With Placebo in Patients With Type 2 Diabetes and Renal Impairment

Type 2 Diabetes

Croatia, United States, Bulgaria, Czech Republic, Poland, Russian Federation, Belarus, Estonia, Germany, Hungary, Latvia, Lithuania, Romania, Ukraine
AstraZeneca
Bristol-Myers Squibb

Completed

Assess Pharmacokinetics, Safety and Tolerability in Healthy Chinese Volunteers After Oral Doses of Saxagliptin

Type 2 Diabetes

China
University of Ulm
Novartis

Withdrawn

Comparison of Telbivudine Versus Lamivudine on the Early Dynamics and Kinetics of Viral Suppression in Chronic Hepatitis B (EVD)

Hepatitis B, Chronic

Germany
Actavis Inc.

Completed

Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fasting Conditions

Healthy

Canada
Jiangsu Simcere Pharmaceutical Co., Ltd.
Second Hospital of Shanxi Medical University

Completed

A Pilot Bioequivalence Study of Pomalidomide

Bioequivalence

China
Pfizer

Completed

Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Taiwan, Slovakia, Mexico, Canada, Hungary
Brigham and Women's Hospital

Completed

Replication of the TECOS Diabetes Trial in Healthcare Claims

Diabetes

United States
Beni-Suef University

Completed

Tubular Markers in Response to Saxagliptin Therapy

Diabetes Mellitus, Type 2

Egypt
National Institute of Diabetes and Digestive and...

Completed

Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

Diabetes Mellitus Type 2 | Diabetes Mellitus Type 1

United States
Samsung Medical Center

Completed

Effect of Evogliptin on Albuminuria in Patients With Type 2 Diabetes and Renal Insufficiency (DA1229)

Renal Insufficiency | Albuminuria | Type2 Diabetes Mellitus

Korea, Republic of
Novo Nordisk A/S

Completed

A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes (SUSTAIN™)

Diabetes Mellitus, Type 2 | Diabetes

Japan
University Hospital, Basel, Switzerland

Completed

Effects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 Diabetes (EXTYPE-1)

Diabetes Mellitus Type 1

Switzerland
Kyowa Kirin Co., Ltd.

Completed

A Phase 2 Study of OPC-262 in Patients With Type 2 Diabetes

Diabetes, Type 2

Japan
Nemours Children's Clinic

Completed

Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis

Cystic Fibrosis

United States
Handok Inc.

Unknown

Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)

Type 2 Diabetes Mellitus

Korea, Republic of
Stanford University
Merck Sharp & Dohme LLC

Completed

Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure (S-001)

Heart Failure, Congestive

United States
Boehringer Ingelheim

Completed

Randomized, Double-blind (db), Placebo-controlled 18 Week Study of Linagliptin (BI 1356) in Type 2 Diabetic Patients With Insufficient Glycaemic Control on a Sulfonylurea Drug

Diabetes Mellitus, Type 2

United States, Argentina, Hungary, India, Japan, Poland, Russian Federation
Boehringer Ingelheim

Completed

Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive

Diabetes Mellitus, Type 2

United States, Australia, Hong Kong, Israel, New Zealand, Ukraine
Takeda

Completed

Pharmacokinetics and Pharmacodynamics Study of Alogliptin in Healthy Korean Participants

Pharmacokinetics and Pharmacodynamics

Korea, Republic of
Takeda

Completed

Long-term Safety of Alogliptin in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Poland, Germany, Argentina, South Africa, Netherlands, Peru, Czech Republic, Brazil, Chile, Guatemala, Dominican Republic
University of Milan

Not yet recruiting

Effects of Sitagliptin in Relatives of T1D Patients (SITA-one)

Type 1 Diabetes

Italy
Beijing Chao Yang Hospital

Recruiting

Sitagliptin for the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Centre Hospitalier Universitaire de Pointe-a-Pitre

Not yet recruiting

Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes (METNODTHYR)

Diabetes Mellitus, Type 2 | Thyroid Nodule (Benign)

France, Guadeloupe, Réunion
Ain Shams University
Ahram Canadian University

Completed

The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy

Type 1 Diabetic Nephropathy

Egypt
University of Nebraska

Terminated

Using Sitagliptin as a Treatment to Prevent New Onset Diabetes After Kidney Transplantation

End Stage Renal Disease | Type 2 Diabetes

United States
Oregon Health and Science University

Suspended

Effects of DPP-4 Inhibition on Triglycerides

Type 2 Diabetes | Hypertriglyceridemia

United States
Hua Medicine Limited

Completed

Drug Interaction Study Between Dorzagliatin and Sitagliptin

Patients

United States
Takeda

Completed

A Study for Post-Marketing Surveillance of Nesina® Tablet Monotherapy or Combination Therapy in Participants With Type 2 Diabetes (T2DM) in South Korea

Type 2 Diabetes Mellitus

Korea, Republic of
Rabin Medical Center

Terminated

Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19

Glucose Metabolism Disorders | Respiratory Tract Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | COVID 19 | Coronavirus | Metabolic Disease | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2 | Hormones | Hypoglycemic Agents | Incretins | Dipeptidyl-Peptidase IV Inhibitors and other conditions

Israel
Rabin Medical Center

Unknown

Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host Disease (GVHD)

Graft Vs Host Disease

Israel
Laval University
Merck Sharp & Dohme LLC

Completed

Sitagliptin Therapy and Kinetics of Inflammatory Markers

Type 2 Diabetes Mellitus

Canada
Takeda

Completed

An Observational Study of Alogliptin Benzoate in Participants With Diabetes Mellitus Type 2

Diabetes Mellitus

Russian Federation
Institut National de la Santé Et de la Recherche...

Completed

A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver Resection (HCC-DPPIV)

Hepato Carcinoma

France
European Foundation for the Study of Diabetes
Eli Lilly and Company; Chinese Medical Association

Completed

Protective Effects of Sitagliptin on β Cell Function in Patients With Adult-onset Latent Autoimmune Diabetes (LADA) (DPP-ⅣLADA)

Type 1 Diabetes

China
Novo Nordisk A/S

Completed

A Retrospective Database Assessment of Clinical Effectiveness in Type 2 Diabetes Patients Treated With Liraglutide From Primary Care Centers in Sweden

Diabetes Mellitus, Type 2 | Diabetes

Sweden
Merck Sharp & Dohme LLC

Completed

Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)

Diabetes Mellitus
Georgetown University
Merck Sharp & Dohme LLC

Terminated

Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers

Type II Diabetes

United States
Novartis Pharmaceuticals

Completed

Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Germany
University of California, San Diego

Completed

Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver Disease

Non-alcoholic Fatty Liver Disease

United States
University of Missouri-Columbia

Withdrawn

Evaluation of the DPP-4 Inhibitor Sitagliptin in the Treatment of Non-Alcoholic Fatty Liver Disease Using MRI

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease

United States
Laval University
Merck Sharp & Dohme LLC

Completed

Sitagliptin and Kinetics of Triglyceride-rich Lipoproteins Apolipoprotein B48 and B100 in Patients With Type 2 Diabetes (JANUB48)

Type 2 Diabetes Mellitus

Canada
Michael A. Nauck

Completed

Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis

Diabetes

Germany
Chong Kun Dang Pharmaceutical

Unknown

Efficacy and Safety of Lobeglitazone Versus Sitagliptin

Diabetes Mellitus, Type 2

Korea, Republic of
ikfe-CRO GmbH
MLM Medical Labs GmbH; Ikfe GmbH

Completed

Effects of Linagliptin on Endothelial- , Renal-, and Retinal Function in Patients With Hypertension and Albuminuria

Albuminuria | Arterial Hypertension

Germany
Assistance Publique - Hôpitaux de Paris

Completed

ACute and Chronic Effects of Saxagliptin (ACCES)

Impaired Glucose Tolerance

France
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers

Healthy
Ono Pharmaceutical Co. Ltd

Completed

MK-0431/ONO-5435 Phase III Clinical Trial - Insulin Add-on Study for Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
AstraZeneca
Bristol-Myers Squibb

Completed

52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period

Type 2 Diabetes

Korea, Republic of, Russian Federation, United Kingdom, Vietnam, Germany, Hungary, Finland, Norway, Netherlands, Slovakia, India
Mayo Clinic

Completed

Incretins in Impaired Fasting Glucose

Pre-diabetes

United States
AstraZeneca

Completed

Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany

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