Search clinical trials for: Dose-adjustment by PKPD

Total 149 results

Hospital de Clinicas de Porto Alegre

Unknown

Incidence of Short-term Urinary Retention After Fascial Retropubic Sling: Prospective and Randomized Analysis.

Stress Urinary Incontinence | Urinary Retention Postoperative | Urinary Retention After Procedure

Brazil
Hadassah Medical Organization

Recruiting

Adjustment of Aminoglycoside Dosing Based on Peak Serum Concentration and Bacterial Minimal Inhibitory Concentration

Aminoglycoside Dosing Based on PK/PD Characteristics

Israel
University Hospital Schleswig-Holstein

Completed

Clinical Application of Electrical Impedance Tomography for Individual Adjustment of Ventilator Settings (CLEAR)

ARDS

Germany
University of Louisville
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Intelligent Control Approach to Anemia Management

End-Stage Renal Disease

United States
Beijing Tongren Hospital

Completed

Novel Dose Adjustment Schedule for Late Injection in SCIT in AR

Allergic Rhinitis | Immunotherapy

China
Belfast Health and Social Care Trust
Hoffmann-La Roche; Medical Research Council; Aerocrine AB

Completed

A Pragmatic Trial of Corticosteroid Optimisation in Severe Asthma

Severe Persistent Asthma

United Kingdom
Shanghai Zhongshan Hospital
Shanghai Fifth People's Hospital,Fudan University

Recruiting

Artificial Intelligence-assisted Insulin System in Type 2 Diabetes in General Wards

Diabetes Type 2

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Paramedical Protocol for Ventilation in Acute Respiratory Distress Syndrome (PARAVENT)

Acute Respiratory Distress Syndrome

France
CR-CSSS Champlain-Charles-Le Moyne

Completed

Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population (VancoDATABayes)

Adult | Vancomycin | Area Under Curve

Canada
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
University of Texas Southwestern Medical Center

Completed

ED50 and ED95 of Isobaric Bupivacaine for Post-Partum Bilateral Tubal Ligation

Anesthesia, Local

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Dose-adjustment of Enoxaparin by a Bayesian Pharmacological Approach in Pediatric Kidney Transplant Recipients (OPTI-TREX) (OPTI-TREX)

Pediatric Kidney Transplant Recipients

France
Universitat Jaume I

Completed

Efficacy of Two Ways of Applying Homework Assignments in the Treatment of Adjustment Disorders

Adjustment Disorders

Spain
GGZ Centraal
ZonMw: The Netherlands Organisation for Health Research and Development; Pa... and other collaborators

Completed

Cost-effectiveness of CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients in Curacao

CYP2D6, Psychiatric Patients

Netherlands
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
St. Louis University

Completed

Buprenorphine Dose Adjustments and Gestational Age

Neonatal Abstinence Syndrome
A.Menarini Asia-Pacific Holdings Pte Ltd

Unknown

Different Level of Single-dose and Multiple-dose Bilastine PK Study in Chinese Population

Pharmacokinetics

China
Arcispedale Santa Maria Nuova-IRCCS

Completed

Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. (GLIORAD)

Glioblastoma | Glioblastoma Multiforme | Glioblastoma, Adult

Italy
ReiThera Srl

Completed

RSV001 - A New Vaccine to Prevent Severe Viral Chest Infections.

Respiratory Syncytial Virus Infections

United Kingdom
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Guided User-initiated Insulin Dose Enhancements (GUIDE) to Improve Outcomes for Youth With Type 1 Diabetes

Type 1 Diabetes
Sir Run Run Shaw Hospital

Recruiting

Molecular Basis of Loss Aversion

Healthy

China
Arrevus Inc.
Arnasi Group

Completed

Oral ARV-1801 Given in Combination With Intravenous Ceftazidime or Meropenem for Treatment of Melioidosis in Hospitalized Patients

Melioidosis

Thailand
Myriad Genetic Laboratories, Inc.

Terminated

Study Comparing Optimized 5-FU Dosing and Standard Dosing in Metastatic Colorectal Cancer Patients Treated With mFOLFOX6 (PROFUSE)

Colorectal Cancer, Metastatic

United States
University of Manitoba
The Hospital for Sick Children; University of British Columbia; McGill University

Enrolling by invitation

Predictors of Persistent Peanut Allergy at Age 5 Years

Allergy to Peanut
ReAlta Life Sciences, Inc.
FGK Clinical Research GmbH

Completed

A Clinical Study to Determine the Safety, Tolerability and Effect of RLS-0071 Doses When Given to Healthy Adults After Inhaling LPS

Healthy

Germany
Centers for Disease Control and Prevention
International Centre for Diarrhoeal Disease Research, Bangladesh; World Health... and other collaborators

Enrolling by invitation

Assessing Immunogenicity of Intramuscular Sabin Inactivated Poliovirus Vaccine and Non-inferiority of Intradermal Fractional Inactivated Poliovirus Vaccine

Poliomyelitis

Bangladesh
University of Utah

Completed

Real-time Anti-Factor Xa Measurements in Surgical Patients to Examine Enoxaparin Metabolism and Optimize Enoxaparin Dose

Venous Thromboembolism | Deep Venous Thrombosis | Pulmonary Embolus

United States
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
University of Utah

Completed

Evaluation of Anti-Xa Levels in Surgery Patients Receiving Weight-based Heparin

Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism

United States
Sanofi Pasteur, a Sanofi Company
Sanofi K.K.

Completed

Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Patients ≥65 Years

Influenza

Japan
Cairo University

Unknown

Soft Tissue Augmentation Around Immediate Implants In The Esthetic Zone

Recession, Gingival
Sun Pharma Advanced Research Company Limited

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPARC1316

Asthma

United Kingdom
Versailles Hospital

Completed

A Prospective Randomized Phase II Study Evaluating the Monitoring of Imatinib Mesylate Plasmatic Through Level in Patients Newly Diagnosed With CP-CML (OPTIMIMATINIB)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

France
University of Utah

Completed

Evaluation of Anti-Xa Levels in Surgery Patients Receiving Fixed Dose Heparin

Venous Thromboembolism | Pulmonary Embolism | Deep-Venous Thrombosis

United States
Federico II University

Completed

Glycaemic Load and Pre-meal Insulin Doses in Type 1 Diabetes Patients (GLUT)

Type 1 Diabetes
Keros Therapeutics, Inc.

Recruiting

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).

Pulmonary Arterial Hypertension

United States, Australia
University Hospital, Ghent

Completed

Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. (C-ART-2)

Primary Non-operated Squamous Cell Carcinoma of Oral Cavity | Primary Non-operated Squamous Cell Carcinoma of Oropharynx | Primary Non-operated Squamous Cell Carcinoma of Hypopharynx | Primary Non-operated Squamous Cell Carcinoma of Larynx

Belgium
Assistance Publique - Hôpitaux de Paris

Completed

Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children (OPTIBAYE)

Methicillin-resistant Staphylococcal Infections

France
Health Institutes of Turkey
TC Erciyes University; Mene Research; Kocak Farma

Not yet recruiting

Evaluation of the Efficacy, Safety and Immunogenicity of Inactivated COVID 19 Vaccine(TURKOVAC) in Healthy Population of 18 and 64 Years of Age (Both Inclusive):a Randomized, Double-blind, Phase IIb Clinical Trial

Covid19

Turkey
Fundacao Champalimaud

Unknown

Single Dose Radiotherapy (SDRT) With or Without Adjuvant Systemic Therapy for Oligometastatic Prostate Cancer

Metastatic Prostate Cancer | Prostate Adenocarcinoma

Portugal
Vanderbilt University
Centers for Disease Control and Prevention

Completed

Cell Mediated Immunity in Older Adults (CMI)

Immunity to Influenza Vaccine

United States
Dawonmedax Co., Ltd.

Recruiting

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

Recurrent Glioblastoma | Recurrent High-grade Glioma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligodendroglioma

Korea, Republic of
University of Utah
Agency for Healthcare Research and Quality (AHRQ)

Completed

Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients

Venous Thromboembolism | Deep Venous Thrombosis | Pulmonary Embolus

United States
H. Lundbeck A/S
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole in Patients With Schizophrenia

Schizophrenia

Serbia, Estonia, United States, Poland, Romania, Russian Federation, Slovakia, Ukraine
University of North Carolina, Chapel Hill
National Center for Complementary and Integrative Health (NCCIH)

Completed

A Study of Sublingual Immunotherapy in Peanut-allergic Children (SLB)

Food Hypersensitivity

United States
Agendia
University of South Florida; University of Miami; University of Oklahoma; Ohio... and other collaborators

Completed

MINT I Multi- Institutional Neo-adjuvant Therapy MammaPrint Project I (MINT)

Breast Cancer

United States
Chinese Academy of Sciences

Completed

The Association of Fast Food Densities With Mortality From Cardiovascular Disease

Cardiovascular Diseases
Chinese Academy of Sciences

Completed

Temperature and Mortality

Cardiovascular Diseases
Otsuka Beijing Research Institute

Terminated

The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder

Major Depressive Disorder

China
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type

Alzheimer Dementia | Agitation Associated With Alzheimer's Dementia

United States

Search clinical trials for: Dose-adjustment by PKPD

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