Search clinical trials for: EMBEDA (morphine sulfate / naltrexone hydrochloride)

Total 691 results

Pfizer

Terminated

Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients

Chronic Pain

United States
Pfizer

Completed

Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo

Chronic Pain | Analgesia | Opioid-related Disorders | Narcotic Abuse
Pfizer

Completed

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Nondependent Opioid Abuse, Episodic

United States
Pfizer

Terminated

Conversion to Embeda With Rescue Trial (ConvERT)

Pain | Chronic Disease

United States
Pfizer

Completed

Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain

Pain

United States
Pfizer

Completed

A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis | Chronic Pain

United States
QRxPharma Inc.

Completed

Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee Arthroplasty

Postoperative Pain

United States
Pfizer

Completed

Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)

Healthy

Canada
QRxPharma Inc.

Completed

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

Postoperative Pain

United States
St Vincent's University Hospital, Ireland

Unknown

Efficacy of Multimodal Opioid Therapy During Hepatic Resection Surgery (RITM-IVM)

Pain | Liver Dysfunction

Ireland
Roxane Laboratories

Completed

Safety and Pharmacokinetic Study of Oral Morphine Sulfate in Pediatric Subjects

Pain

United States
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Nova Scotia Health Research... and other collaborators

Completed

Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD) (ROS-003)

Chronic Obstructive Pulmonary Disease (COPD)

Canada
QRxPharma Inc.

Completed

Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty

Postoperative Pain

United States
Minia University

Unknown

Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.

Pain, Postoperative | Pruritus | Nausea, Postoperative | Vomiting, Postoperative

Egypt
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA); Arthritis Foundation

Completed

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

Depression | Anxiety | Degenerative Disc Disease | Chronic Low Back Pain

United States
Fatma Adel El sherif,MD

Completed

Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?

Postoperative Complications

Egypt
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Completed

Quadratus Lumborum Block in Pediatric Patients

Postoperative Pain
The University of Texas Health Science Center,...

Terminated

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

Pain, Postoperative

United States
University of Alabama at Birmingham

Active, not recruiting

Decreased Neuraxial Morphine After Cesarean Delivery

Anesthesia

United States
Assiut University

Completed

Dosage of Epidural Morphine in Elderly Patients

Abdominal Cancer | Age Problem

Egypt
Mundipharma Korea Ltd

Completed

An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion. (SWITCH)

Cancer Pain

Korea, Republic of
Stanford University

Terminated

Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans

Inflammation

United States
Mayo Clinic

Terminated

Methadone Versus Morphine for Cancer-Related Pain

Neoplasms | Pain

United States
MedtronicNeuro

Terminated

Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side Effects (CONVERT-TDD)

Chronic Pain

United States
Indiana University

Completed

Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome

Neonatal Abstinence Syndrome | Neonatal Opioid Withdrawal Syndrome | Neonatal Opioid Withdrawal

United States
QRxPharma Inc.

Completed

Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain

Postoperative Pain

United States
San Diego State University

Recruiting

Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Placebo | Naltrexone

United States
Fujian Cancer Hospital

Not yet recruiting

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Cancer Pain

China
Assiut University

Unknown

Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain

Chronic Pain

Egypt
Centre Hospitalier Universitaire de Nīmes

Completed

Oxycodone Versus Intravenous Morphine for Postoperative Analgesia After Hip Surgery

Arthroplasty, Replacement, Hip

France
University College Dublin
National Children's Research Centre; Our Lady's Children's Hospital, Crumlin

Completed

Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children

Pain | Sickle Cell Disease

Ireland
simon.haroutounian

Completed

Epidural Methadone in Healthy Volunteers

Pain, Acute

United States
Qianfoshan Hospital

Not yet recruiting

Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled

Pulmonary Nodule | Ablation
Xuanhan County People's Hospital

Completed

Postoperative Analgesic Effect of Esketamine

Analgesia | Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor

China
Actavis Inc.

Completed

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on Applesauce

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions

Healthy

United States
Hildrun Haibel
DLR German Aerospace Center

Active, not recruiting

NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint

Knee Arthritis

Germany
Massachusetts General Hospital

Completed

Effect of Combined Morphine and Duloxetine on Chronic Pain (Duloxetine)

Chronic Low Back Pain | Chronic Neck Pain

United States
BioDelivery Sciences International

Completed

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

Pain

United States
Medical University of Lublin

Recruiting

Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia

Quality of Life | Vulvodynia | Naltrexone

Poland
Central Hospital, Nancy, France

Completed

Analgesic Efficacy of Transmucosal Fentanyl for Breakthrough Pain Caused by Interventional Gastrostomy (ANTALGIP)

Gastrostomy | Breakthrough Pain | Upper Aerodigestive Tract Neoplasms

France
Duke University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease

Sickle Cell Disease

United States
Procare Riaya Hospital

Completed

The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction Study

Postoperative Pain

Saudi Arabia
Baylor College of Medicine

Terminated

Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia

Pain, Postoperative

United States
Icahn School of Medicine at Mount Sinai
U.S. Department of Education

Completed

Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury

Neuropathic Pain | Spinal Cord Injury

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Association pour le Développement et l'Organisation...

Completed

Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICU (DYS-NOC)

Dyspnea

France

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