Search clinical trials for: GEn-1124

Total 4747 results

GEn1E Lifesciences

Recruiting

A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)

Respiratory Distress Syndrome, Acute

United States
GEn1E Lifesciences

Completed

Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of GEn1E-1124

Healthy

New Zealand
Swiss Vision Network

Active, not recruiting

Longitudinal Study on Glaucoma Surgery Using XEN® Gel Stent

Glaucoma | Glaucoma, Open-Angle | Glaucoma, Angle-Closure | Glaucoma, Primary Open Angle
Henry Ford Health System
University of Michigan; Geisinger Clinic

Completed

Encouraging Young Adults to Make Effective Nutrition Choices (MENU GenY)

Improve Dietary Behaviors in Young Adults 21-30 Years of Age

United States
Guang'anmen Hospital of China Academy of Chinese...

Unknown

Trial of Different Dosages' Ge Gen Qin Lian Decoction in the Treatment of Type 2 Diabetes

Diabetes Mellitus, Type 2 | Dose-Response Relationship, Drug

China
Vir Biotechnology, Inc.
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19 (COMET-PEAK)

Covid19

United States, Canada, Italy, Korea, Republic of, Spain
Institut de l'oeil des Laurentides

Recruiting

A Prospective, Single Surgeon, Randomized Control Study Comparing ab Interno XEN Gel Microstent Implantation vs Closed Conjunctiva ab Externo Implantation Performed at the Slit Lamp for the Treatment of Uncontrolled Glaucoma

The Objective of the Study is to Prospectively Compare the Success Rate of ab Externo and Interno Implantation

Canada
Allergan

Completed

XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS) (XEN GPS)

Glaucoma

United States
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Daiichi Sankyo Co., Ltd.

Completed

Study of DS-1123a in Advanced Solid Tumours

Advanced Solid Malignant Tumors

Japan
Nguyen Thi Trieu, MD

Completed

Composition for Treating Cirrhosis and Liver Cancer (SB-1121) (SB-1121)

Cirrhosis of the Liver

Vietnam
Claret Medical
Meditrial Europe Ltd.

Completed

Carotid Filtration During Endovascular Aortic Valve Implantation

Heart Diseases
Complejo Hospitalario Universitario de Albacete
University of Castilla-La Mancha

Recruiting

"Efficacy of Intermittent Enteral Nutrition Versus Continuous Administration in Intensive Care" (ENINCO)

Enteral Nutrition | Critical Care | Gastric Feeding Tube | Feeding Methods

Spain
Seno Medical Instruments Inc.

Suspended

Clinical Evaluation of Opto-Acoustic Image Quality With the Gen1B Duplex Probe in Breast Applications

Breast Cancer

United States
NImmune Biopharma

Completed

Safety Tolerability and Pharmacokinetics of Oral NIM-1324 in Healthy Adult Male and Female Volunteers

Normal Healthy Volunteers

Australia
NorthSea Therapeutics B.V.

Completed

A Phase 1, First Time in Humans Study of NST-1024

Hypertriglyceridemia

United Kingdom
Attralus, Inc.

Active, not recruiting

A Study to Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic Amyloidosis (AT01-001)

Amyloidosis

United States
Aquinox Pharmaceuticals (Canada) Inc.
Innovaderm Research Inc.

Completed

Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis (KINSHIP)

Atopic Dermatitis

Canada
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Hepatic Impairment Study

Hepatic Impairment

Czech Republic, Poland, Slovakia
Repros Therapeutics Inc.

Terminated

Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine Fibroids

Uterine Fibroids

United States
ProQR Therapeutics

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene (AURORA)

Eye Diseases | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies | Vision Disorders | Retinal Disease | Autosomal Dominant Retinitis Pigmentosa | Vision Tunnel

United States
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
Fidia Farmaceutici s.p.a.

Completed

Performance and Safety of Hyalo Gyn Gel on the Treatment of Vaginal Atrophy in Postmenopausal Women

Vulvovaginal Atrophy

Slovakia
Abbott Medical Devices

Completed

Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy (CEA) (PROTECT) (PROTECT)

Carotid Artery Disease

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

Recurrent Pleural Malignant Mesothelioma | Stage IV Pleural Mesothelioma

United States
Tempest Therapeutics

Completed

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Non-small Cell Lung Cancer | Urothelial Carcinoma | GastroEsophageal Cancer | Triple-Negative Breast Cancer | Metastatic Castration Resistant Prostate...

United States
Aquinox Pharmaceuticals (Canada) Inc.

Unknown

Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome (LEADERSHIP 301)

Interstitial Cystitis | Painful Bladder Syndrome | Bladder Pain Syndrome | Chronic Interstitial Cystitis

United States, Belgium, Canada, Czechia, Denmark, Hungary, Latvia, Netherlands, Poland, Romania, Spain, United Kingdom
Promontory Therapeutics Inc.

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Urogenital Neoplasms | Neoplasms by Site | Genital Neoplasms, Male | Prostatic Neoplasms | Advanced Solid Tumors | mCRPC | Metastatic Castrate-resistant Prostate Cancer | CRPC | PT-112

United States, France
Bausch Health Americas, Inc.

Completed

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects

Atopic Dermatitis

United States
Invicro

Completed

Evaluation of [18F]MNI-1126 as an Imaging Marker for Synaptic Density Loss

Parkinson Disease | Alzheimer Disease | Healthy Volunteers

United States
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Efficacy and Safety of AQX-1125 in Unstable COPD (FLAGSHIP)

COPD

United States, New Zealand, Poland, Australia, Denmark, Finland, Hungary, Sweden
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Children's Mercy Hospital Kansas City
Eurofins

Recruiting

Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant Recipients

Liver Failure, Acute | Liver Transplant; Complications

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Nintedanib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenocarcinoma | Endometrial Transitional Cell Carcinoma | Endometrial Mucinous Adenocarcinoma | Endometrial Squamous Cell Carcinoma | Malignant Uterine Corpus Mixed Epithelial and Mesenchymal Neoplasm

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University
Allergan

Active, not recruiting

XEN45 in the Treatment of Chinese Patients With Primary Open-angle Glaucoma

Glaucoma | Glaucoma, Open-Angle | Surgery

China
Boehringer Ingelheim

Completed

BIBF 1120 + Docetaxel (Japan) in Patients With Advanced Non-small-cell Lung Cancer, Phase I

Carcinoma, Non-Small-Cell Lung

Japan
Boehringer Ingelheim

Completed

Efficacy and Safety of Oral Treatment With BIBF 1120 ES in Advanced Non-small-cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
Bausch Health Americas, Inc.

Completed

Efficacy and Safety of IDP-124 Lotion for the Treatment of Moderate to Severe Atopic Dermatitis in Pediatric and Adult Subjects (301)

Atopic Dermatitis

United States
SciClone Pharmaceuticals

Unknown

An Open-label Phase I/II Clinical Trial of PT-112 Injection for Advanced Solid Tumors and Advanced Hepatocellular Carcinoma

Advanced Solid Tumors

China
Boehringer Ingelheim

Terminated

BIBF 1120 in Combination With Pemetrexed in Advanced Non Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Japan
ORIC Pharmaceuticals

Completed

Effect of Food on the Pharmacokinetics of ORIC-114

Food Effect in Healthy Participants

Australia
Promontory Therapeutics Inc.

Completed

A Phase 1/2a Dose-Finding Study of PT-112 in Patients With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma

United States
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
KLE VK Institute of Dental Sciences

Completed

Effectiveness of Locally Delivered Morus Alba Gel on Moderate Periodontitis

Chronic Periodontitis
Aquinox Pharmaceuticals (Canada) Inc.

Terminated

Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Canada, United States
Takeda

Completed

TAK-114 Single- and Multiple-Dose Phase 1 Study

Clinical Pharmacology

Japan
Lipocine Inc.

Active, not recruiting

A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial

NASH - Nonalcoholic Steatohepatitis

United States
FORUM Pharmaceuticals Inc

Terminated

Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease

Dementia | Alzheimer's Disease

United States, France, United Kingdom, Spain, Argentina, Canada, Netherlands, Korea, Republic of, Australia, Czech Republic, Germany, Italy, Mexico, South Africa

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