Search clinical trials for: GLPG0259 solution

Total 19280 results

Pharmacotherapies for Alcohol and Substance Use...
Yale University; United States Department of Defense; VA Connecticut Healthcare... and other collaborators

Completed

Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study

Post Traumatic Stress Disorder (PTSD) | Alcohol Use Disorder (AUD)

United States
Eben Rosenthal
National Cancer Institute (NCI)

Completed

Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Head and Neck (SCCHN)

United States
Crossject

Completed

Bioavailability Study of Midazolam Administered as a Solution by Conventional Syringe or ZENEO®

Healthy

South Africa
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma (EXPEDITION)

Asthma

Denmark, United States, Canada, Germany, Sweden, United Kingdom
Huazhong University of Science and Technology

Completed

Intravenous Dexamethasone and Dexmedetomidine on the Analgesic Efficacy of Erector Spinae Plane Block

Dexmedetomidine | Dexamethasone | Nerve Block

China
EMS

Completed

Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification

Ocular Inflammation | Cataract

Brazil
Michigan State University

Completed

Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise

Exercise | Insulin

United States
Helsinki University Central Hospital

Completed

Patient-controlled Sedation With Propofol and Remifentanyl for Endoscopic Retrograde Cholangiopancreatography (ERCP)

Endoscopic Retrograde Cholangiopancreatography

Finland
St. Paul's Hospital, Canada

Withdrawn

N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Media

Otitis Media | Otorrhea

Canada
Peking Union Medical College

Unknown

Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion

Breast Cancer | Lung Cancer | Malignant Pleural Effusion
Tomas Bata Hospital, Czech Republic
Faculty Hospital Kralovske Vinohrady

Completed

Comparison of Different Low Volume Solutions Prior to Colonoscopy

Colonoscopy

Czechia
Assiut University

Completed

Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children

Oncological Children

Egypt
Kasr El Aini Hospital

Completed

Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery

Quality of Ocular Akinesia (Onset and Duration)

Egypt
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
University of Aarhus

Completed

Protracted Effect of the Ultrasound-guided Saphenous Block (PEUSB)

Arthrosis, Unspecified, Ankle and Foot

Denmark
United States Naval Medical Center, San Diego
United States Naval Medical Center, Portsmouth

Completed

Comparing the Effects of Ultrasound Versus Fluoroscopy for Sacroiliac Joint Injections

Sacroiliitis

United States
Vanderbilt University

Terminated

Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED

Nausea

United States
Federal University of São Paulo
Alcon Research

Completed

Safety/Efficacy of Antibiotic Steroid Combination in Treatment of Blepharitis and/or Keratitis and/or Conjunctivitis (BRA-07-02)

Conjunctivitis | Keratitis | Blepharitis

Brazil
Peking University Third Hospital

Recruiting

A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients

Chronic Kidney Disease

China
Chiesi Farmaceutici S.p.A.

Recruiting

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

COPD | COPD Exacerbation

United States, Bulgaria, Hungary, Poland, Argentina, Czechia, Mexico, Canada, Puerto Rico, Romania
Montefiore Medical Center

Recruiting

Pilocarpine Use After Kahook Goniotomy (PAACK)

Glaucoma

United States
Sheba Medical Center

Recruiting

Efficacy and Necessity of Time Interval Between Instillation of Two Glaucoma Eye Drops

Glaucoma | Glaucoma; Drugs

Israel
Kirsehir Ahi Evran Universitesi

Completed

Comparison of IPACK Block and PCI for Postoperative Analgesia and Function Recovery Following Total Knee Arthroplasty

Total Knee ArthroplastyKnee Pain, Functionality

Turkey
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adults, Adolescents, Children, and Toddlers in India and Healthy Adolescents and Children in the Republic of South Africa (MET55)

Healthy Volunteers (Meningococcal Infection)

India, South Africa
University of Patras

Completed

Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy

Lung Diseases | Anesthesia | Diagnosis

Greece
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood

Healthy

Germany
Novartis Pharmaceuticals

Completed

Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer (BOLERO-4)

Hormone Receptor Positive Breast Cancer

United States, Argentina, Thailand, Japan, France, Korea, Republic of, Spain, Turkey, Hungary, United Kingdom, Portugal, Brazil, Netherlands
Cairo University

Completed

Anesthetic Efficacy of %4Alexadricaine Versus %2 Mepicaine-L in Children

Local Anesthesia

Egypt
Mayo Clinic

Enrolling by invitation

Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty

Total Knee Arthroplasty

United States
Nicholas Bastidas

Withdrawn

The Effects of Injection Site Cooling and Solution Buffering on Perceived Pain During Local Anesthesia Administration

Pain
Sanofi

Completed

A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus

Type1 Diabetes Mellitus

Germany
Sanofi

Completed

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period (LixiLan-G)

Type 2 Diabetes Mellitus

Estonia, Italy, Israel, United States, Canada, Germany, Romania, Slovakia, Spain
Bristol-Myers Squibb

Completed

Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)

Non-small Cell Lung Cancer

United States, Canada
University of Pecs

Enrolling by invitation

Plasma Concentration of Lidocaine and Bupivacaine Axillary BPB Mixture Solutions [PCLBAxMix] (PCLBAxMix)

Arm Injury

Hungary
Tribhuvan University, Nepal
National Medical College, Birgunj, Nepal

Completed

Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block

Oral Surgical Procedure

Nepal
Aalborg University

Withdrawn

Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% as a New Surrogate Model of Itch

Itch

Denmark
Alexion Pharmaceuticals
Celerion; Achillion, a wholly owned subsidiary of Alexion

Completed

A Drug Interaction Study of ACH-0145228

Healthy

United States
Baxalta now part of Shire
Kamada, Ltd.

Terminated

A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD

Graft Versus Host Disease

United States
Haseki Training and Research Hospital

Completed

Comparison of the Efficacy of Irrigation With Epinephrine or Tranexamic Acid on Visual Clarity

Rotator Cuff Tears

Turkey
Milton S. Hershey Medical Center

Terminated

Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size

Cataract
Yuria-Pharm

Terminated

Efficacy and Safety of Intravenous Treatment of Tuberculosis

Tuberculosis, Pulmonary

Ukraine
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma (VENTURE)

Asthma

Belgium, Israel, United States, Mexico, Argentina, Brazil, Canada, Chile, Colombia, Hungary, Italy, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
Fresenius Kabi

Completed

Blood Glucose Response After Oral Intake of Lactulose in Mildly Constipated Patients With Diabetes Mellitus Type 2

Diabetes Mellitus, Type 2

Austria
University of Minnesota

Completed

TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy

Acute Pain

United States
University of Texas Southwestern Medical Center
Forest Laboratories

Completed

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Hypertension

United States
University of California, Davis
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Withdrawn

Role of Chemokine and Chemokine Receptor in Psoriasis

Psoriasis

United States
University of Aarhus

Completed

Diameter Changes of Retinal Vessels During Hypoxia

Diabetic Maculopathy | Diabetes Mellitus Type 1

Denmark
Kenneth Taylor, M.D.

Terminated

Pain With Trigger Finger Injection: A Comparison of Steroid Alone Versus Steroid/Lidocaine Mixture

Trigger Finger Disorder

United States
Avanir Pharmaceuticals

Completed

Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants

Healthy Adult Male and Female Volunteers

United States
Ain Shams University

Unknown

Wound Infiltration With Ketorolac Versus Lidocaine for Postoperative Analgesia After Total Abdominal Hysterectomy

Anesthesia

Egypt

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