Search clinical trials for: Intrathecal (IT) Methotrexate

Total 2072 results

Mohamed Youssef Mohamed

Recruiting

Comparison Between IT Fentanyl and IV Granisetron in Prevention of Vomiting in CS Under Spinal Anesthesia

Nausea and Vomiting, Postoperative

Egypt
Kresimir Oremus, MD

Completed

PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty

Postoperative Pain | Total Hip Arthroplasty

Croatia
University of Chicago
National Cancer Institute (NCI)

Terminated

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

Extensive Stage Small Cell Lung Cancer | Recurrent Small Cell Lung Cancer

United States
Cairo University

Completed

Intrathecal Nalbuphine is a Comparable Safer Alternative to Fentanyl for Intraoperative Pain Management During Uterine Exteriorization

Pain, Acute

Egypt
The First Hospital of Jilin University

Completed

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Leptomeningeal Metastasis

China
St. Jude Children's Research Hospital
Gateway for Cancer Research

Completed

Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage

Acute Myeloid Leukemia

United States
Mansoor Aman, MD

Recruiting

Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

Chronic Pain | Neuropathic Pain | Cancer Pain | Cancer Associated Pain

United States
International Extranodal Lymphoma Study Group (IELSG)

Withdrawn

A Phase I Study of Intrathecal Rituximab in Patients With Lymphomatous Meningitis

Lymphoma, B Cell
M.D. Anderson Cancer Center

Terminated

Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

Leukemia | Metastatic Malignant Neoplasm to the Leptomeninges | Lymphoid Malignancies

United States
Pfizer

Completed

Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Mexico, Argentina, Chile, Croatia, Czech Republic, Hungary, Poland, Puerto Rico
Johnson & Johnson Consumer Inc. (J&JCI)

Completed

Clinical Trial to Evaluate Safety and Efficacy of a Facial and Lip Moisturizer in Adult Subjects Undergoing a Facial Dermatologic Procedure With Fractional CO2 Laser

Skin Regeneration After Dermatological Facial Procedure With Fractional CO2 Laser

Brazil
St. Jude Children's Research Hospital
Ohio State University; Arog Pharmaceuticals, Inc.

Completed

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Acute Myeloid Leukemia

United States
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
University Hospitals Cleveland Medical Center

Completed

Determining the Prognostic Value of Continuous Intrathecal Infusion

Chronic Low Back Pain | Vertebral Compression Fracture | Failed Back Surgery Syndrome | Lumbar Post-Laminectomy Syndrome

United States
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Omalizumab (Xolair) and Allergy Shots For the Treatment of Seasonal Allergies

Hypersensitivity | Allergy | Rhinitis | Hay Fever

United States
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Completed

The Effect of Analgesia Methods Applied in Gynecological Cancer Surgeries on Postoperative Analgesia

Regional Anesthesia Morbidity | Gynecological Cancer Surgery

Turkey
Arizona State University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); San Diego State... and other collaborators

Recruiting

Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention

Alcohol Use Disorder | Domestic Violence | Intimate Partner Violence | HIV-infection/Aids

Uganda
Nanjing Medical University

Completed

Neuraxial Anesthesia and Restless Leg Syndromes in Cesarean (NARELESS)

Cesarean Section | Restless Leg Syndrome

China
Myovant Sciences GmbH

Completed

Study of Relugolix Alone and Relugolix Combined With Hormonal Add-Back Therapy in Healthy Premenopausal Female Participants

Healthy

United States
University Hospital Freiburg

Completed

Prospective, Randomised, Single-Blinded, Monocentric Clinical Study to Compare Postoperative Analgesia and Outcome After Combined Paravertebral and Intrathecal Versus Thoracic Epidural Analgesia for Thoracotomy

Pain, Postoperative

Germany
South Egypt Cancer Institute

Completed

Safety and Efficacy of Intrathecally Administered Magnesium Sulfate

Abdominal Pain | Abdominal Cancer

Egypt
Samsung Medical Center

Not yet recruiting

Pilot Study for the Validity of a Content-based Information Provision Tool Aimed at Improving the Hospitalization Experience of Liver Transplant Patients

Liver Transplantation | Inpatients
T3 Pharmaceuticals AG

Recruiting

First in Human Study of T3P-Y058-739 (T3P)

Advanced Solid Tumor

United Kingdom, Switzerland
Molnlycke Health Care AB

Terminated

Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia

Leg Ulcer | Diabetic Foot Ulcer | Pressure Ulcer

Sweden
W.J. Pasman

Completed

The Potential of Do-it-yourself Devices for Obtaining Personal Health Data (P4@TNO)

Health Behaviour Change | Self-monitoring of Health

Netherlands
VA Office of Research and Development
University of Pittsburgh

Recruiting

Nitrite Supplementation in Long COVID Patients

Long COVID | Cardiorespiratory Fitness

United States
University Hospitals of Derby and Burton NHS Foundation...
Keele University

Recruiting

Thumb Osteoarthritis Prognosis for Supported Self-managment (TOPS)

Osteoarthritis Thumb

United Kingdom
Data Collection Analysis Business Management
PAS Research Services

Unknown

Usage and Plan of Care Changes Due to Drug Screenings

Pain Management
Assiut University

Not yet recruiting

Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine

Inguinal Hernia
AstraZeneca

Completed

PK Study of Ticagrelor in Children Aged Less Than 24 Months, With Sickle Cell Disease (HESTIA4) (HESTIA4)

Sickle Cell Disease

Belgium, United Kingdom, Italy, Spain, Kenya, Lebanon
Vestre Viken Hospital Trust
Oslo University Hospital; University Hospital of North Norway; Helse Stavanger... and other collaborators

Recruiting

Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung Cancer (LUNGVAC)

Oncology | NSCLC Stage IV | NSCLC, Stage III

Norway
Darell Bigner
National Cancer Institute (NCI); Genentech, Inc.; Istari Oncology, Inc.

Active, not recruiting

D2C7-IT With Atezolizumab for Recurrent Gliomas

Malignant Glioma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination

Papillomavirus Vaccines

United States
University of Split, School of Medicine

Recruiting

Efficacy and Safety Assessment of Niacinamide Cosmetic Preparation: a Randomized Controlled Trial

Dry Skin; Eczema | Skin Hyperpigmentation

Croatia
University of California, San Diego

Completed

Validation of the Short-term Antimicrobial Action of Transplanted Bacteria

Atopic Dermatitis

United States
MedImmune LLC

Completed

A Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung Cancer (D4190C00006)

NSCLC | Lung Cancer | Non-small Cell Lung Cancer

United States, France, Italy, Spain, Belgium, United Kingdom, Korea, Republic of, Australia, Taiwan
Codman & Shurtleff

Terminated

Long-term Surveillance of the MedStream Programmable Infusion System

Spasticity

United States
St. Jude Children's Research Hospital
AbbVie; Gateway for Cancer Research; Karyopharm Therapeutics Inc

Recruiting

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia | Acute Myeloid Leukemia, in Relapse | Acute Leukemia of Ambiguous Lineage in Relapse | Refractory Acute Leukemia of Ambiguous Lineage

United States
Spineology, Inc

Completed

Rampart Duo Clinical (RaDical) Post-Market Study (RaDical)

Lumbar Degenerative Disc Disease

United States
Cairo University

Completed

Laser Acupuncture in Rheumatoid Arthritis Geriatric Patients

Rheumatoid Arthritis

Egypt
Chugai Pharma Taiwan

Completed

Study of Tocilizumab in Combination With Methotrexate for Treatment of Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis (RA)

Taiwan
Mansoura University

Completed

Ultrasonography Versus Palpation for Spinal Anesthesia in Obese Parturients Undergoing Cesarean Delivery

Cesarean Section | Anesthesia, Spinal | Spinal Ultrasound

Egypt
Ashutosh Kumar Tewari
Oncovir, Inc.

Completed

Neoadjuvant Hiltonol® (PolyICLC) for Prostate Cancer

Prostate Cancer

United States
CHA University

Completed

Methotrexate Treatment for Ectopic Pregnancy

Ectopic Pregnancy

Korea, Republic of
Regina Elena Cancer Institute
Federico II University

Recruiting

Immunotolerance in Endometrial Cancer and at the Maternal-fetal Interface: Immunological Profiling of the Tumor Microenvironment in Risk Stratification of Recurrence

Endometrial Cancer

Italy
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of MP-435 in Combination With Methotrexate (MTX) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Czech Lymphoma Study Group

Unknown

CNS Prophylaxis in Diffuse Large B-cell Lymphoma (CLSG-CNS-001)

Diffuse Large B-cell Lymphoma

Czech Republic
medac GmbH

Completed

Preference Methotrexate (MTX) Pre-filled Syringe Versus Pre-filled Pen in Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Germany
Sun Yat-sen University

Unknown

Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL

Leukaemia,Lymphoblastic

China
Helsinki University Central Hospital
Foundation for Paediatric Research, Finland; Päivikki and Sakari Sohlberg Foundation... and other collaborators

Completed

Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE-JIA)

Juvenile Idiopathic Arthritis

Finland

Search clinical trials for: Intrathecal (IT) Methotrexate

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