Search clinical trials for: Mineralocorticoid Receptor Antagonists

Total 37498 results

Boehringer Ingelheim

Completed

This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated

Diabetic Nephropathies

Spain, Germany, United Kingdom, France, Greece, Portugal, Sweden, Russian Federation, Denmark, Slovakia
TC Erciyes University

Completed

Spironolactone Against Anthracycline-induced Cardiomyopathy

Anthracycline Induced Cardiotoxicity

Turkey
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment

Obstructive Sleep Apnea | Hyperaldosteronism | Resistant Hypertension

United States
Pfizer

Terminated

A Study To Evaluate The Efficacy Of Eplerenone Compared With Losartan For The Treatment Of Patients With Mild To Moderate Hypertension

Hypertension

Taiwan
Chiang Mai University

Unknown

Effect of Add-on Spironolactone to Losartan Versus Losartan Alone on Peritoneal Membrane Among Peritoneal Dialysis Patients (ESCAPE-PD)

Peritoneal Dialysis | End Stage Renal Disease

Thailand
Wake Forest University Health Sciences

Withdrawn

Non-Responsive Diabetic Macular Edema and Spironolactone

Diabetic Maculopathy

United States
University of Southern Denmark

Completed

The Role of Aldosterone in Circulatory Disorders Within Type 2 Diabetes

Insulin Resistance | Endothelial Dysfunction

Denmark
Columbia University

Completed

Mineralocorticoid Receptor Antagonists (MRA) in Heart Failure (HF) and Loop Diuretic Resistance

Heart Failure

United States
University Hospital, Caen
Ministry of Health, France

Unknown

Spironolactone and Perioperative Atrial Fibrillation Occurrence in Cardiac Surgery Patients. (ALDOCURE)

Atrial Fibrillation | Cardiac Surgery | Aldosterone Blockade

France
Dr Irmela MANTEL

Completed

Adjuvant Anti-Mineralocorticoid-Receptor Treatment in Anti-VEGF Refractory Neovascular Age-Related Macular Degeneration

Neovascular Age-related Macular Degeneration
Nagoya University

Unknown

Eplerenone and Aliskiren Research Targeting Hypertensive Patients With Left Ventricular Hypertrophy (EARTH)

Hypertensive Left Ventricular Hypertrophy

Japan
Laboratories Leon Farma, S.A.
Chemo France

Completed

Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles

Contraception

United States
Poznan University of Medical Sciences

Completed

Reduction of Left Ventricular Hypertrophy After Eplerenone Therapy

Obstructive Sleep Apnea | Left Ventricular Hypertrophy | Hypertension,Essential
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Unknown

Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
CMP Development, LLC

Not yet recruiting

A Phase IV, Two-part, Open-label Study Assessing the Pharmacokinetics, Safety and Pharmacodynamics of Spironolactone Oral Suspension in Pediatric Patients

Edema Due to Heart Failure or Cirrhosis

India
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE)

Endstage Renal Disease

Canada, Australia, United Kingdom, New Zealand, Malaysia, Brazil, India, Philippines, Uruguay, Ecuador
Daiichi Sankyo, Inc.

Completed

A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Hypertensive Subjects

Essential Hypertension

Japan
The University of Texas Health Science Center at...
Relypsa, Inc.

Completed

High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure

Acute Decompensated Heart Failure

United States
University of British Columbia

Completed

Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss

Female Pattern Hair Loss

Canada
Parc de Salut Mar

Completed

Sympathetic Renal Denervation Versus Increment of Pharmacological Treatment in Resistant Arterial Hypertension.

Resistant Arterial Hypertension

Spain
University of Colorado, Denver

Withdrawn

Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure

Pulmonary Hypertension | Right Heart Failure

United States
Asan Medical Center

Completed

Pilot Study on Withdrawal of Spironolactone Among Heart Failure With Improved Ejection Fraction

Heart Failure

Korea, Republic of
Montreal Heart Institute
Pfizer

Completed

Comparison of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes (SNOW)

Heart Failure | Glucose Intolerance | Type 2 Diabetes

Canada
VA Office of Research and Development

Completed

Antiarrhythmic Effects of Spironolactone in Patients With ICDs (SPIRIT)

Ventricular Arrhythmias

United States
Maastricht University Medical Center

Terminated

Aldosterone Antagonism and Microvascular Function

Hypertension | Insulin Resistance | Abdominal Obesity Metabolic Syndrome

Netherlands
Creighton University

Terminated

Aldosterone Blockade to Prevent Myocardial Remodeling In Patients With Controlled Essential Hypertension (Aldosterone)

Myocardial Remodeling

United States
US Department of Veterans Affairs

Completed

Aldosterone Antagonism in Diastolic Heart Failure

Congestive Heart Failure | Diastole

United States
Pfizer

Completed

Compare Effectiveness of Eplerenone vs Atenolol in Reversing the Remodelling Resistance Arteries in Subjects With HT

Hypertension

Canada
Medical University of Gdansk

Completed

Optimalization of Nephroprotection Using Agents Inhibiting Renin-Angiotensin-Aldosterone System

Proteinuria | Chronic Kidney Disease
Professor Fernando Figueira Integral Medicine Institute
Federal University of São Paulo

Completed

Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients

Coronary Artery Calcification | Vascular Calcification

Brazil
University Magna Graecia

Completed

Spironolactone Plus Metformin in Polycystic Ovary Syndrome

Polycystic Ovary Syndrome
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1 (HARP)

Hiv | Alcohol Use Disorder

United States
West Virginia University Healthcare

Unknown

Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease

Chronic Lung Disease | Bronchopulmonary Dysplasia

United States
University of Pavia

Completed

Canrenone as Add-on in Patients With Essential Hypertension

Essential Hypertension
University of Florida
National Heart, Lung, and Blood Institute (NHLBI); Pfizer

Completed

EWISE: Study of Eplerenone in Women With Chest Pain, Coronary Vascular Dysfunction and Evidence of Myocardial Ischemia

Ischemic Heart Disease

United States
Assiut University

Unknown

Non Invasive Assessment of Heart Failure

Heart Failure
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Efficacy and Safety of Finerenone vs. Spironolactone in Patients With Primary Aldosteronism (FAVOR)

Primary Aldosteronism

China
Children's Hospital of Philadelphia
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Fibrosis and the Fontan

Single-ventricle

United States
University of Virginia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Hyperandrogenemia and Altered Day-night LH Pulse Patterns (CRM008)

Polycystic Ovary Syndrome | Hyperandrogenism | Puberty

United States
Leiden University Medical Center
Radboud University Medical Center; Academisch Medisch Centrum - Universiteit...

Unknown

Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy (SPECT)

Chronic Central Serous Chorioretinopathy

Netherlands
Alhasan Mujtaba Abdul-Wahid
Ministry of Health-Basra Health Directorate-Al-Sader Teaching Hospital

Completed

The Effect of Spironolactone on Acute Kidney Injury in Patients Undergoing Coronary Angiography

Acute Kidney Injury | Contrast-induced Nephropathy | IHD

Iraq
Brigham and Women's Hospital
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Joslin...

Withdrawn

L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD (LAST-D)

Hemodialysis | End Stage Renal Disease

United States
Central Hospital, Nancy, France

Completed

Search of Biomarkers of Mineralocorticoid Receiver Activity : the Value of Neutrophil Gelatinase Associated Lipocalin (NGAL)in Serum or Urine in Human

Cardiovascular Diseases

France
Medical University of South Carolina
University of South Carolina

Completed

Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study (TRH)

Hypertension

United States
Second Xiangya Hospital of Central South University
Baxter Healthcare Corporation

Unknown

Residual Renal Function Preservation in Peritoneal Dialysis Patients

Chronic Renal Disease

China
National Institute on Drug Abuse (NIDA)

Recruiting

Spironolactone in Alcohol Use Disorder (SAUD)

Alcohol Use Disorder

United States
Children's Mercy Hospital Kansas City

Completed

Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents

PCOS

United States
Tufts Medical Center

Completed

Eplerenone for Central Serous Chorioretinopathy

Central Serous Chorioretinopathy

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Terminated

Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin B

Patients With Fungic Infections

Mexico
National Taiwan University Hospital

Unknown

Postoperative Cardiovascular Index Change of Primary Aldosteronism (TAIPAI)

Aldosteronism

Search clinical trials for: Mineralocorticoid Receptor Antagonists

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