Search clinical trials for: OPB-51602

Total 802 results

Horizon Therapeutics, LLC

Completed

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Urea Cycle Disorder

United States, Canada
Nihon Pharmaceutical Co., Ltd

Completed

Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.

Neuromyelitis Optica Spectrum Disorder

Japan
Nihon Pharmaceutical Co., Ltd

Completed

Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Chronic Inflammatory Demyelinating Polyneuropathy.

Chronic Inflammatory Demyelinating Polyneuropathy

Japan
Alcon Research

Completed

Acute Comfort and Haze Profile of FID 114657

Dry Eye
University College Cork
Novozymes A/S

Recruiting

The Symbiont-Restore Study

Obesity

Ireland
Molnlycke Health Care AB

Completed

Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty

Arthroplasties, Hip Replacement | Arthroplasties, Knee Replacement

United States
Olympus Biotech Corporation

Completed

A Prospective Pilot Study of the OP-1 Putty in Uninstrumented Posterolateral Fusions

Degenerative Lumbar Spondylolisthesis

United States
Corporacion Parc Tauli
Department of Health, Generalitat de Catalunya; Fundació Parc Taulí

Completed

Wich is the Best Dressing in Wounds by Primary Surgery of THA and / or TKA?

Hip Surgery | Knee Surgery | Nursing | Occlusive Dressings

Spain
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study of OPC-41061 Orally Disintegrating (OD) Tablets Using 2 Different Formulations and 2 Dosing Regimens in Healthy Adult Male Subjects

Healthy Adult Male

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Multicenter, Open-label, Dose-finding Trial of OPC-41061 to Investigate Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety in Patients With Carcinomatous Edema (Phase 2)

Carcinomatous Edema

Japan
Federico II University

Completed

Evaluation of Retinal and Vascular Features in Radiation Maculopathy After Intravitreal Injections of Ranibizumab

Radiation Maculopathy
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (TEMPO 2:4)

Polycystic Kidney, Autosomal Dominant

United States
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)

Autosomal Recessive Polycystic Kidney Disease (ARPKD)

United States, Belgium, Spain, Germany, United Kingdom, Poland
Opthea Limited

Completed

A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macular Edema

Diabetic Macular Edema

United States, Israel, Australia, Latvia
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis

Atopic Dermatitis

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study Comparing a DTaP-HB-PRP~T Combined Vaccine With Tritanrix HepB/Hib™, Concomitantly With OPV in Healthy Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Influenza

Philippines
Hacettepe University

Completed

The Effect of the Cognitive Orientation to Daily Occupational Performance Approach for Children With Organic Acidemia

Organic Acidemia | Cognitive Orientation

Turkey
Otsuka Pharmaceutical Co., Ltd.

Completed

A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) [Extension of Study 156-05-002]

Autosomal Dominant Polycystic Kidney Disease

Japan
Mahidol University

Recruiting

Treatment of Intermittent Claudication by G-CSF-mobilized PB-MNC

Intermittent Claudication | Atherosclerotic Ischemic Disease | PAD

Thailand
University Hospital of Patras

Completed

Comparison of the Efficacy of Nepafenac 0.1% and Nepafenac 0.3 % on Pain Associated With Intravitreal Injections

Pain

Greece
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar I Disorder.

Bipolar I Disorder | Acute Mania

United States, Serbia, Bulgaria, Croatia, Poland, Ukraine
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 2, Multi-center, Open-label, Dose-finding Trial to Investigate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of OPC-41061 in Patients With Chronic Renal Failure Undergoing Hemodialysis or Hemodiafiltration

Chronic Renal Failure

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study of OPC-41061 in Subjects With Cardiac-induced Edema (Congestive Heart Failure)

Cardiac Edema

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

Evaluation Study of the Bioavailability of Brexpiprazole Orally Disintegrating Tablets in Healthy Male Subjects

Healthy Adult Male

Japan
Opthea Limited

Completed

A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD

Neovascular Age-related Macular Degeneration

United States, Czechia, France, Hungary, Israel, Italy, Latvia, Poland, Spain, United Kingdom
ART Fertility Clinics LLC

Recruiting

Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?

Infertility | Infertility, Female

United Arab Emirates
Otsuka Pharmaceutical Development & Commercialization...

Completed

Tolvaptan Extension Study in Participants With ADPKD (TEMPO 4/4)

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States, Australia, Belgium, Germany, Italy, Poland, Romania, United Kingdom, Argentina, Canada, France, Netherlands, Russian Federation
Otsuka Pharmaceutical Development & Commercialization...

Completed

Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Italy, Spain, Sweden, United States, Canada, Australia, Netherlands, Czechia, Poland, Denmark, Israel, Hungary, Russian Federation, South Africa, United Kingdom, Romania, Argentina, Norway
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders

ADHD | Conduct Disorder | Oppositional Defiant Disorder | Autism | Bipolar I Disorder

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Double-blind, Placebo-controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)

Edema, Cardiac

Japan
Azienda Ospedaliera Universitaria Integrata Verona
Smith & Nephew Wound Management Inc

Completed

Efficacy of NPWT in Reducing the Incidence of Wound Infection After Pancreatic Surgery

Surgical Site Infection

Italy
Hadassah Medical Organization
Israel Cancer Association; Israel cancer research fund

Completed

Combined Model of Online Remote Interventions for Cancer-Related Cognitive Impairment (CRCI)

Cancer | Cognitive Decline

Israel
VA Office of Research and Development

Completed

Cognitive-Behavioral Conjoint Therapy (CBCT) Project (CBCT)

Post Traumatic Stress Disorder

United States
Orpheris, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of OP-101 After Intravenous Administration in Healthy Volunteers

Healthy

United States
CHU de Reims

Completed

Cell Therapy in Chronic Limb Ischemia

Peripheral Vascular Diseases

France
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder for Subjects That Have Completed Participation in 331-201-00148

Irritability Associated With Autism Spectrum Disorder

United States
Opthea Limited

Active, not recruiting

OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD) (COAST)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Austria, Brazil, Bulgaria, Canada, Colombia, Croatia, Czechia, Denmark, Estonia, France, Germany, Greece, Hungary, India, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Netherlands, Philippines and more
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Canada Pharmaceutical Inc.; Lundbeck Canada Inc.

Completed

Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder

Major Depressive Disorder

Canada
Lawson Health Research Institute

Unknown

Comparison of Paracoracoid Subscapularis Plane Block to Interscalene Block for Arthroscopic Shoulder Surgery (SPBvsISB)

Rotator Cuff Injury

Canada
Otsuka Pharmaceutical Co., Ltd.

Completed

A Study to Investigate Pharmacodynamics and Pharmacokinetics of OPC-41061 in Patients With Hepatic Edema

Cirrhosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial to Investigate the Efficacy of OPC-41061 Administered at a Dose of 7.5 mg in Patients With Hepatic Edema

Cirrhosis

Japan
Otsuka Pharmaceutical Co., Ltd.

Completed

A Clinical Pharmacological Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)

Cardiac Edema

Japan
Sheba Medical Center

Unknown

Pascal Pascal Dynamic Contour Tonometer (DCT) Intraocular Pressure and Ocular Pulse Amplitude in Patients With Thyroid Related Orbitopathy: A Comparison to Goldmann Tonometer and to Muscles Characteristics on CT Scan

Thyroid Related Orbitopathy

Israel
Horizons International Peripheral Group
Advanced Catheter Therapies, Inc.

Completed

The COPPER-B Trial (COPPER-B)

Cardiovascular Diseases | Arterial Occlusive Diseases | Peripheral Arterial Disease | Peripheral Vascular Disease | Critical Limb Ischemia

United States
Bial - Portela C S.A.

Completed

An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites

Parkinson's Disease (PD)

Netherlands
University of Cologne

Completed

Prospective, Randomized Study of 2 Different Wound Dressings (Close)

Hip-surgery | Knee-surgery | Spinal-surgery

Germany
Women's Hospital HUS

Not yet recruiting

Early Recovery After Cesarean Delivery - Maternal Glucose Homeostasis Following Preoperative Glucose Dose

Cesarean Section Complications | Gestational Diabetes

Finland
Orpheris, Inc.

Completed

A Clinical Study to Measure the Effect of OP-101 After Being Administered Subcutaneous in Healthy Volunteers

Healthy

Australia
Chinese University of Hong Kong

Recruiting

Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: Selective Trunk Block vs Supraclavicular Brachial Plexus Block

Musculoskeletal Diseases or Conditions

Hong Kong
Otsuka Pharmaceutical Development & Commercialization...

Completed

Evaluating the Safety and Tolerability of Brexpiprazole in the Treatment of Adults With Borderline Personality Disorder (BPD)

Borderline Personality Disorder

United States

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