Search clinical trials for: OTX-000

Total 9914 results

Celgene

Completed

Safety and Pharmacokinetics of AVL-292 Following Multiple Doses and the Effect of Food on the Single-dose Pharmacokinetics of AVL-292

Healthy

United States
Beijing Jishuitan Hospital

Unknown

Radial Extracorporeal Shock Wave Therapy on Chronic Low Back Pain: a Prospective Controlled Study

Low Back Pain

China
University Hospital, Tours

Completed

Effect of Vitamin D on Cognitive Decline of Patients With Memory Complaint (D-COG)

Memory Disorders | Age-Related Cognitive Decline

France
Universidad Autonoma de Ciudad Juarez

Completed

Physiological Effect of Ataulfo Mango (Manguifera Indica) Beverage in Exercise

Exercise-induced Oxidative Stress
Ocular Therapeutix, Inc.

Completed

To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease

Dry Eye

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation; iCo Therapeutics Inc.

Terminated

A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated Intravitreal Injections of iCo-007 as Monotherapy or in Combination With Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema (the iDEAL Study) (iDEAL)

Diabetic Macular Edema

United States
University of North Carolina, Chapel Hill
Northwestern University; GlaxoSmithKline; University of Utah; MNGI Digestive Health...

Completed

Mepo for Eosinophilic Esophagitis (EoE) Study

Eosinophilic Esophagitis | EoE

United States
Adele Sparavigna

Unknown

Tolerance and Efficacy Evaluation of 3 Face Creams (FILLER)

Skin Aging

Italy
Benjamin Izar

Terminated

ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma (ATX-101)

Leiomyosarcoma | Liposarcoma

United States
Cook Group Incorporated

Completed

Formula PTX Renal Stent Clinical Study

Renal Artery Stenosis

United Kingdom, Germany, Czechia, France
GWT-TUD GmbH
Miltenyi Biomedicine GmbH

Terminated

Immunoadsorption in Patients With Severe Systemic Sclerosis

Systemic Scleroderma

Germany
University Hospital, Toulouse

Terminated

Evaluation of the Entresto Effect on Sympathic Nervous System in Patient With Heart Failure (B2AN-SNS)

Heart Failure

France
Emory University
National Cancer Institute (NCI); Prostate Cancer Foundation

Recruiting

Vidutolimod (CMP-001) in Combination With Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma

United States
EpicentRx, Inc.

Recruiting

RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer (KEVLARx)

Oral Mucositis

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF) (IRONMETHFpEF)

Iron-deficiency | Heart Failure With Preserved Ejection Fraction

United States
Janssen Pharmaceutical K.K.

Completed

Safety, Pharmacokinetics, and Pharmacodynamics Study of Single Dose of CNTO 3649 in Healthy Adult Men and Multiple Doses of CNTO 3649 in Participants With Type 2 Diabetes Mellitus

Healthy | Diabetes Mellitus, Type 2

Japan
Janssen Research & Development, LLC

Completed

A Study of Different Oral Thin Film (S)-Ketamine Formulations for Sublingual Administration in Healthy Participants

Healthy

Belgium
GlaxoSmithKline
Parexel

Completed

SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma. (AUSTRI)

Asthma

United States, Australia, Poland, Russian Federation, Spain, Ukraine, Germany, Bulgaria, Argentina, Peru, South Africa, Taiwan, Belgium, Italy, Hungary, Korea, Republic of, Austria, Romania, Colombia, Slovakia, United Kingdom, Mexico and more
Tizona Therapeutics, Inc

Active, not recruiting

TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers

Cancer

United States
SFJ Pharmaceuticals, Inc.
SFJ Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 With and Without Ticagrelor Pretreatment in Chinese Healthy Volunteers

Healthy

China
Brigham and Women's Hospital
National Center for Maternal and Child Health Research, Mongolia; Zuun Kharaa...

Completed

Trial of Vitamin D Supplements to Raise Calcidiol Levels of Pregnant Women in Mongolia

Vitamin D Deficiency | Pregnancy

Mongolia
Calm Water Therapeutics LLC
Andover Research Eye Institute

Completed

Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops

Dry Eye Disease

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies (GALECRUSTED)

Ivermectin | Gale | Severe Forms of Scabies | Oral Parasitic Drug

France
Lawson Health Research Institute

Completed

Pleurodesis Using Hypertonic Glucose to Treat Post-operative Air Leaks (PLUG-I)

Postoperative Air Leak

Canada
AstraZeneca
Parexel

Completed

Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871

Chronic Obstructive Pulmonary Disease COPD

Germany, United Kingdom
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Drug Interaction Between CKD-519 and Rosuvastatin in Healthy Male Subjects

Dyslipidemias

Korea, Republic of
Topcon Medical Systems, Inc.

Withdrawn

Non-Invasive Imaging of the Human Eye

Willing and Able Subjects for Ocular Imaging

United States
Radboud University Medical Center

Completed

Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease (ANIDULAPK)

Leukemia | Leukemia, Myeloid, Acute | Myelodysplastic Syndrome

Netherlands
Adocia

Completed

A Clinical Trial Investigating the Intra-subject Variability of Pharmacokinetics and Glucodynamics of BioChaperone Insulin Lispro U-100 Product and U-200 Product in Healthy Volunteers

Healthy

Germany
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M4344 in Participants With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

Spain, United States, Netherlands, United Kingdom
Scientific Laboratory Products, Ltd.

Completed

Comparing the Sleep Strip OTC™ Accuracy in Screening for Sleep Apnea Syndrome Against the Reference Method, an In-lab Full Night Polysomnographic (PSG)

Sleep Apnea Syndrome

Israel
Ocular Therapeutix, Inc.

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease.

Dry Eye Disease

United States
Mayne Pharma International Pty Ltd

Terminated

A Safety, Efficacy and Systemic Exposure Study of CD5789 Cream in Adults and Adolescents With Lamellar Ichthyosis

Lamellar Ichthyosis

United States, Spain, Canada, Germany, France, Australia, Israel, Ukraine, United Kingdom
Pfizer

Active, not recruiting

A Study to Learn About Abrocitinib Tablets in People With Atopic Dermatitis in India

Atopic Dermatitis

India
Medicines for Malaria Venture
Washington University School of Medicine; Sanaria Inc.; Institute of Tropical... and other collaborators

Completed

Safety, Tolerability and Chemoprotective Activity of P218 in PfSPZ Challenge Model

Malaria

Belgium
Celularity Incorporated

Completed

Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU

Diabetic Foot | Peripheral Arterial Disease

United States
Pfizer

Completed

A Study to Assess the Pharmacokinetics of Ceftaroline in End Stage Renal Disease Patients and Matched Healthy Subjects

Renal Disease

United Kingdom
Cook Group Incorporated

Completed

Zilver PTX Drug-Eluting Peripheral Stent Study

Peripheral Arterial Disease

Germany, Switzerland
Amicus Therapeutics

Active, not recruiting

Gene Therapy for Children With CLN3 Batten Disease

Batten Disease | CLN3

United States
PepTonic Medical AB
Pharma Consulting Group AB

Completed

Dose-relationship of Vaginally Administrated Oxytocin in Postmenopausal Women (OXYPEP002)

Vaginal Atrophy

Sweden
Marius Henriksen

Terminated

Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure (TOCIVID)

Corona Virus Disease

Denmark
Tianjin Medical University Cancer Institute and...

Unknown

Clinical Application of Nutrition Support Package Before Hepatectomy

Liver Neoplasms | Hepatectomy | Nutrition Therapy

China
TrippBio, Inc.

Not yet recruiting

A Relative Bioavailability Study With a Novel PanCytoVir™ Oral Suspension (100 mg/ml)

Relative Bioavailability
Eli Lilly and Company

Completed

Study to Compare 2 Formulations of LY900014 in Healthy Participants

Healthy

Singapore
University of Versailles
Assistance Publique - Hôpitaux de Paris; Association Française contre les Myopathies...

Completed

Efficacy and Safety of DHEA for Myotonic Dystrophy

Myotonic Dystrophy

France
Medical University of Graz

Completed

Effects of Infliximab on Insulin Sensitivity and Beta Cell Function in Insulin Resistant Human Obesity

Obesity | Metabolic Syndrome | Insulin Resistance

Austria
Columbia University

Withdrawn

Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder

Chronic Fatigue Syndrome

United States
AstraZeneca

Completed

Study of Verinurad in Heart Failure With Preserved Ejection Fraction (AMETHYST)

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States, Germany, Canada, Korea, Republic of, Austria, Slovakia, Australia, Bulgaria, Russian Federation, Argentina, Poland, Mexico
St. Joseph's Healthcare Hamilton

Recruiting

Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery

Thyroid Diseases | Postoperative Pain | Anesthesia, Local

Canada
Seoul Medical Center

Completed

ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty

Spinal Anesthesia | Total Knee Replacement Arthroplasty

Korea, Republic of

Search clinical trials for: OTX-000

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