Search clinical trials for: PO Placebo

Total 53907 results

University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Improving Treatment Outcomes for Prescription Opioid Dependence (GBN)

Drug Dependence

United States
University of Nottingham
University of Oxford; Nottingham University Hospitals NHS Trust; University of... and other collaborators

Completed

Helicobacter Eradication Aspirin Trial (HEAT)

Bacterial Infection Due to Helicobacter Pylori (H. Pylori) | Gastrointestinal Ulcer Haemorrhage

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis

Lupus Nephritis

United States, Canada, France, Russian Federation, United Kingdom
Gynecologic Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenocarcinoma | Stage III Uterine Corpus Cancer AJCC v7 | Stage IIIA Uterine Corpus Cancer AJCC v7 | Stage IIIB Uterine Corpus Cancer... and other conditions

United States
Vejle Hospital

Terminated

Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer (Toco-Pulm)

Lung Cancer

Denmark
Cairo University

Unknown

Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression

Symptomatic Irreversible Pulpitis
Glenmark Pharmaceuticals Ltd. India

Completed

To Study GSP 301 in Patients With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
ORA, Inc.

Completed

Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model

Allergic Conjunctivitis

United States
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States, Bulgaria, Canada, Colombia, Estonia, France, Germany, Hungary, Italy, Korea, Republic of, Latvia, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine, United Kingdom
Glenmark Pharmaceuticals Ltd. India

Completed

To Study Generic Calcipotriene and Betamethasone Dipropionate Topical Foam, 0.005%/0.064%, in the Treatment of Psoriasis Vulgaris (Plaque Psoriasis).

Psoriasis Vulgaris

United States
Mahmoud Samy Abdallah

Completed

Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder

Major Depressive Disorder
Peking University People's Hospital

Unknown

Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome (CTRIPS)

Sjogren's Syndrome

China
University of Wisconsin, Madison

Completed

ACL Repair and Multimodal Analgesia

Pain

United States
Cetylite Industries

Completed

Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers

No Disease State or Condition

United States
Genentech, Inc.

Completed

A Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus (EXPLORER)

Lupus Erythematosus, Systemic

United States, Canada
University of Colorado, Boulder
Forest Laboratories

Completed

Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)

Hypertension | Prehypertension

United States
Glenmark Pharmaceuticals Ltd. India

Completed

Efficacy and Safety of Fixed Dose Combination (FDC) of Olopatadine Hydrochloride and Mometasone Furoate Nasal Spray (Molo; Also Referred as GSP 301) in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301- PoC)

Seasonal Allergic Rhinitis

Canada
University of Vermont

Unknown

Addition of Clonidine to Ropivacaine in Adductor Canal Block

Postoperative Pain

United States
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Effect Of SAR153191 (REGN88) Added To Other RA Drugs In Patients With RA Who Are Not Responding To Or Intolerant Of Anti-TNF Therapy (SARIL-RA-TARGET)

Rheumatoid Arthritis

Hungary, Portugal, Austria, United States, Argentina, Australia, Brazil, Canada, Czechia, Germany, Greece, Guatemala, Israel, Italy, Korea, Republic of, Lithuania, Mexico, New Zealand, Peru, Poland, Romania, Russian Federation, Spain, Taiwa... and more
Seoul National University Hospital
Seoul National University Bundang Hospital

Completed

Efficacy of Ropivacaine (With Epinephrine) in BABA Endoscopic and Robotic Thyroidectomy (REBT)

Goiter | Thyroid Neoplasm

Korea, Republic of
City of Hope Medical Center
OSI Pharmaceuticals

Completed

Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Pfizer

Completed

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders. (CATS)

Smoking Cessation

United States, Spain, Germany, Canada, South Africa, Finland, Denmark, Australia, Argentina, Brazil, Bulgaria, Chile, Mexico, New Zealand, Russian Federation, Slovakia
B.P. Koirala Institute of Health Sciences

Completed

Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.

Postoperative Sore Throat, Cough, Hoarseness

Nepal
Al Hayat National Hospital
Menoufia University

Unknown

Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence?

IUD Insertion Complication

Egypt, Saudi Arabia
University of Pittsburgh

Completed

Incomplete Response in Late Life Depression: Getting to Remission (IRL GREY) (IRL GREY)

Depression

United States, Canada
Imperial College London
Nuon Therapeutics, Inc.

Withdrawn

Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Symptom Burden in Head and Neck Cancer

Head And Neck Cancer

United States
Orexigen Therapeutics, Inc

Completed

A Safety and Efficacy Study of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects Participating in an Intensive Behavior Modification Program

Obesity | Overweight

United States
Turku University Hospital

Completed

Effects of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sublingual and Intravenous Buprenorphine

Healthy

Finland
AstraZeneca

Completed

Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

Drug Induced Constipation

United States
Genentech, Inc.

Completed

A Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic Despite Treatment With H1 Antihistamines, H2 Blockers, and/or Leukotriene Receptor Antagonists

Chronic Idiopathic Urticaria

Germany, United Kingdom, United States, Switzerland, Australia, New Zealand, Poland, Singapore
Jens Borglum Neimann

Completed

Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy

Postoperative Pain | Postoperative Nausea and Vomiting | Postoperative Function Level

Denmark
University of Turku
Orion Corporation, Orion Pharma

Completed

Competition With Striatal [11C]ORM-13070 Binding by Atipamezole and Endogenous Noradrenaline (AIMI)

Healthy

Finland
Sanofi

Completed

Long Term Safety of Teriflunomide When Added to Interferon-Beta or Glatiramer Acetate in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada, Germany, Italy, Spain, United Kingdom, Austria
Novartis

Completed

Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine

Pain, Migraine

United States
Sheba Medical Center

Unknown

Minocycline, Acetylsalicylic Acid or Pramipexole vs Placebo in Patients With Schizophrenia or Schizoaffective Disorder (MAP-S-01)

Schizophrenia | Schizoaffective Disorder

Israel, Romania
AstraZeneca

Completed

Budesonide / Formoterol in Treatment of Exacerbations of COPD

Chronic Obstructive Pulmonary Disease

Netherlands
Orasi Medical, Inc.

Completed

Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test

Healthy

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myelodysplastic Syndrome | Clonal Cytopenia of Undetermined Significance

United States
Egymedicalpedia

Not yet recruiting

The Effect of Dexmedetomidine, Melatonin and Pregabalin

Endoscopic Sinus Surgery

Egypt
Indonesia University

Not yet recruiting

Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

Arthroplasty Complications | Pregabalin | Analgetic | Celecoxib
Children's Oncology Group

Recruiting

A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors

Central Nervous System Carcinoma

United States, Puerto Rico
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States, China
Ultragenyx Pharmaceutical Inc

Terminated

Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)

Glycogen Storage Disease Type III

United States, Spain, Italy
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder

Binge-Eating Disorder

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous Leukemia... and other conditions

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Breast Cancer

Japan, Poland, United States, Australia, Belgium, Brazil, Canada, China, Colombia, Costa Rica, France, Germany, Hungary, Ireland, Israel, Korea, Republic of, New Zealand, Portugal, Puerto Rico, Russian Federation, Spain, Taiwan, Ukr... and more
University of Pennsylvania

Completed

Stress and Inflammation in Late-Life Depression (S&I)

Depression | Inflammation

United States
Zealand University Hospital

Completed

Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Orthopaedic Surgery of the Foot and Ankle (ADJUNCT2)

Anesthesia, Local

Denmark

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