Search clinical trials for: PUL-042 Inhalation Solution

Total 457 results

Pulmotect, Inc.
United States Department of Defense

Completed

The Use PUL-042 to Reduce the Infection Rate and Progression to COVID-19 in Adults Exposed to SARS-CoV-2

COVID-19

United States
Pulmotect, Inc.

Completed

Safety and Tolerability of Single Ascending Doses of PUL-042 Inhalation Solution in Healthy Subjects

Healthy

United States
Pulmotect, Inc.
United States Department of Defense

Completed

The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection

COVID-19

United States
Pulmotect, Inc.
Imperial College Healthcare NHS Trust; VirTus Respiratory Research Ltd; MWB Consulting... and other collaborators

Completed

The Effect of Inhaled PUL-042 on Rhinovirus-induced Symptoms in Smokers With GOLD Stage 0 COPD

COPD

United Kingdom
Pulmotect, Inc.
National Heart, Lung, and Blood Institute (NHLBI); Cancer Prevention Research...

Withdrawn

A Multiple Ascending Dose Study of PUL-042 in Stem Cell Transplant Recipients

Hematologic Diseases | Stem Cell Transplants

United States
Aires Pharmaceuticals, Inc.

Completed

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers (AIR001-CS02)

Pulmonary Arterial Hypertension

United States
Pharmosa Biopharm Inc.
PPD

Completed

Single Ascending Dose Study for Evaluation of Safety, Tolerability and Pharmacokinetics of L606

Pulmonary Arterial Hypertension

United States
Aires Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
Pharmosa Biopharm Inc.
Novotech (Australia) Pty Limited

Recruiting

Safety, Tolerability and Pharmacokinetics of L608 in Healthy Adults

Pulmonary Arterial Hypertension

Australia
Mylan Pharma UK Ltd.

Completed

Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD)

COPD

China
Aires Pharmaceuticals, Inc.

Terminated

A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Australia, Hungary
National Jewish Health

Unknown

Use of DNAse in Neutrophilic Asthma

Neutrophilic Asthma

United States
Meiji Seika Pharma Co., Ltd.

Completed

Pharmacokinetics and Safety Study of ME1100 in Healthy Volunteers

Healthy

United States
Erik Allen Jensen
University of Florida

Active, not recruiting

Inhaled Tobramycin in BPD

Bronchopulmonary Dysplasia

United States
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Foresee Pharmaceuticals Co., Ltd.

Completed

Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045

Healthy Volunteers

Australia
Gerard Turino

Completed

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

Emphysema | Alpha 1-Antitrypsin Deficiency

United States, Canada
Bitop AG

Active, not recruiting

Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. (EIL-AST)

Asthma

Poland
Bitop AG

Completed

Efficacy and Feasibility of Ectoin® Inhalation Solution in Inflammatory Obstruction and Ageing of the Lung (EFECT)

COPD | Particulate Matter Induced Inflammation of the Lung

Germany
Mylan Pharma UK Ltd.

Completed

Fasting Bioavailability Study of Mylan's Revefenacin Inhalation Solution

Healthy Volunteers Bioavailability Study

China
Merck Sharp & Dohme LLC

Terminated

Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642) (DEFY)

Cystic Fibrosis
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

Denmark, New Zealand, Spain
Merck Sharp & Dohme LLC

Terminated

Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease

Cystic Fibrosis
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

Phase Ia Study of XW001 in Healthy Adult Subjects

Respiratory Syncytial Virus Infections

China
University College, London

Completed

Nebulised Dornase Alfa for Treatment of COVID-19 (COVASE)

Hypoxia | COVID19

United Kingdom
University of Missouri-Columbia

Completed

Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) (DORNASESARS2)

SARS-CoV 2 | ARDS

United States
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
GlaxoSmithKline

Completed

GSK573719 IV Enabling Study

Pulmonary Disease, Chronic Obstructive

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study in Adult and Pediatric Patients With Cystic Fibrosis

Cystic Fibrosis
Kexing Biopharm Co., Ltd.

Recruiting

Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract Infections

Respiratory Syncytial Virus Infections

China
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis (GUERANDE)

Acute Viral Bronchiolitis

France
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease

Cystic Fibrosis

United States, Australia, Canada, New Zealand
Boehringer Ingelheim

Completed

Dose Extension Study of BIIX 1 XX in Healthy Young Male Volunteers

Healthy
Medical Center Alkmaar

Completed

Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis (BATTLE)

Non-CF Bronchiectasis

Netherlands
Meiji Seika Pharma Co., Ltd.

Completed

A Study to Assess the Pharmacokinetic Profile, the Safety, and the Tolerability of ME1100 Inhalation Solution in Patients With Mechanically Ventilated Bacterial Pneumonia

Pneumonia, Bacterial

United States
Children's Hospital of Philadelphia

Completed

Hypertonic Saline for Acute Bronchiolitis

Saline Solution, Hypertonic | Bronchiolitis, Viral

United States
Ajou University School of Medicine

Not yet recruiting

Desflurane and Sevoflurane on Remifentanil Requirement

Spinal Diseases
Merck Sharp & Dohme LLC

Terminated

Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701)

Interstitial Lung Disease
Merck Sharp & Dohme LLC

Completed

A Safety and Tolerability Study of Denufosol in 2-4 Year Olds (REACH-1)

Cystic Fibrosis
Fondation Ophtalmologique Adolphe de Rothschild
University Hospital, Strasbourg, France; Centre Hospitalier Régional Metz-Thionville

Terminated

Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE) (COVIDORNASE)

COVID-19 | Acute Respiratory Distress Syndrome

France
Merck Sharp & Dohme LLC

Completed

A Study to Diagnose Lung Cancer by Sputum Cytology (01-312)

Lung Cancer
Novartis Pharmaceuticals

Completed

Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis (EAGER)

Cystic Fibrosis

United States, Germany, United Kingdom, Colombia, Spain, France, Netherlands, Israel, Canada, Italy, Chile, Australia, Hungary, Mexico
Northwestern University
Genentech, Inc.

Unknown

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

Head and Neck Cancer

United States
NovaBay Pharmaceuticals, Inc.

Unknown

Efficacy Study of Auriclosene Irrigation Solution on Urinary Catheter Patency

Urinary Catheter Blockage and Encrustation

United States
BioMarck Pharmaceuticals, Ltd.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD (BREATH-1)

Chronic Obstructive Pulmonary Disease | COPD

United States
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease

Cystic Fibrosis
B. Braun Melsungen AG

Terminated

Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)

Renal Insufficiency

Germany
Rigel Pharmaceuticals

Completed

Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2) (DROPS-2)

Chronic Graft-versus-host Disease

United States
Apeiron Biologics
Apeiron Respiratory Therapies GmbH

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Inhaled APN01 Developed as Treatment for COVID-19

Covid19

Austria

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