Search clinical trials for: placebo to adalimumab

Total 60516 results

Hoffmann-La Roche

Completed

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Germany, Spain, Sweden, United Kingdom, United States, Brazil, Greece, Portugal, Turkey, Finland, Switzerland, Australia, Mexico, Czech Republic
Gilead Sciences
Galapagos NV

Terminated

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Are Naive to Biologic DMARD Therapy (PENGUIN 1)

Psoriatic Arthritis

Korea, Republic of, United States, Taiwan, Australia, Canada, Japan, Poland, Spain, New Zealand, Czechia, Hungary, Bulgaria, Russian Federation
Gilead Sciences
Galapagos NV

Completed

Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate (FINCH 1)

Rheumatoid Arthritis

United States, Italy, Poland, Ukraine, Belgium, Hong Kong, Taiwan, Spain, Israel, Bulgaria, India, Serbia, South Africa, Korea, Republic of, Japan, Russian Federation, Argentina, Germany, New Zealand, Thailand, Hungary, Netherlands, Slovaki... and more
Samsung Bioepis Co., Ltd.

Completed

A Study Comparing SB5 to Humira® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Lithuania, Poland
Abbott

Completed

Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Abbott

Completed

Study of Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Idiopathic Arthritis (JIA)

Arthritis, Juvenile Idiopathic

United States, Belgium, Czech Republic, France, Germany, Italy, Slovakia, Spain
AbbVie

Active, not recruiting

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) (SELECT - PsA 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic... and more
Abbott

Completed

Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severely Active Psoriatic Arthritis Subjects With Inadequate Response to Disease Modifying Anti-Rheumatic Drug Therapy

Arthritis | Psoriatic
Abbott

Completed

Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis

Arthritis | Psoriatic
Abbott

Completed

Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Abbott

Completed

Extension Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis
Abbott

Completed

Safety and Efficacy of Adalimumab in Patients With Active Ankylosing Spondylitis

Ankylosing Spondylitis

Canada
Abbott

Completed

Human Anti-tumor Necrosis Factor (TNF) Monoclonal Antibody Adalimumab in Subjects With Active Ankylosing Spondylitis (ATLAS)

Ankylosing Spondylitis

United States
Abbott

Completed

Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis (CHAMPION)

Psoriasis

United States
Abbott
Eisai Co., Ltd.

Completed

A Study of Adalimumab in Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Abbott

Completed

Remission in Subjects With Crohn's Disease, 1 Year Phase (CLASSICII)

Crohn's Disease

United States
AbbVie (prior sponsor, Abbott)

Completed

A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis

Enthesitis Related Arthritis (ERA)
Assistance Publique - Hôpitaux de Paris
Abbott

Completed

HECTHOR: Humira to Spare Steroids in Giant Cell Arteritis

Giant Cell Arteritis

France
AstraZeneca

Terminated

Randomised Double-Blind, Placebo-Controlled, Parallel Group Study in Patients With Active Rheumatoid Arthritis:Magnetic Resonance Imaging Sub-Study (OSKIRA 4 SS)

Rheumatoid Arthritis

United States, Bulgaria, Russian Federation, South Africa, United Kingdom, Germany, Hungary, Netherlands, Canada, Czech Republic, Poland
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study of Adalimumab in the Treatment of Hidradenitis Suppurativa (PIONEER II)

Hidradenitis Suppurativa (HS)
AbbVie

Completed

Study to Evaluate the Safety and Efficacy of Adalimumab in Chinese Subjects With Moderate to Severe Crohn's Disease

Crohn's Disease
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study of Adalimumab in Treatment of Hidradenitis Suppurativa (PIONEER I)

Hidradenitis Suppurativa (HS)
Peter Higgins
AbbVie

Withdrawn

Calprotectin-Directed Humira® Maintenance Therapy (CADHUM) (CADHUM)

Crohn's Disease

United States
Grupo Espanol de Trabajo en Enfermedad de Crohn...
Abbott; TFS Trial Form Support

Terminated

Assessment of Mucosal Activity to Improve the Prognosis of Patients With Crohn's Disease Treated With Immunosuppressants (ADACAL)

Crohn's Disease | Mucosal Inflammation

Spain, France, Belgium
Abbott
Eisai Co., Ltd.

Completed

A Study of Adalimumab for the Maintenance of Clinical Remission in Japanese Subjects With Crohn's Disease

Crohn's Disease

Japan
Takeda

Completed

An Efficacy and Safety Study of Vedolizumab Intravenous (IV) Compared to Adalimumab Subcutaneous (SC) in Participants With Ulcerative Colitis

Colitis, Ulcerative

United States, Belgium, Israel, Spain, Korea, Republic of, Taiwan, Netherlands, Australia, Denmark, Hungary, Russian Federation, Italy, Croatia, Hong Kong, Germany, Portugal, Serbia, Canada, Poland, Bulgaria, Ukraine, Colombia, Turkey, Czech... and more
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
AbbVie

Completed

Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis

Axial Spondyloarthritis
Abbott

Completed

Efficacy and Safety of Adalimumab in Adult Chinese Subjects With Active Ankylosing Spondylitis

Ankylosing Spondylitis

China
Abbott
Eisai Co., Ltd.; Abbott Japan Co.,Ltd

Completed

A Study of Adalimumab for the Induction of Clinical Remission in Japanese Subjects With Crohn's Disease

Crohn's Disease

Japan
Abbott

Completed

Study Comparing 80 mg of Adalimumab With Placebo, and Demonstrating the Non-inferiority of Monthly 80 mg Adalimumab Dosing Compared With 40 mg Adalimumab Every Other Week Dosing

Rheumatoid Arthritis

United States, Canada, Puerto Rico, Australia, Germany, United Kingdom
Abbott

Completed

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis

Ulcerative Colitis

United States, Austria, Belgium, Canada, Czech Republic, Germany, Hungary, Italy, Netherlands, Poland, Puerto Rico, Slovakia, Sweden
Canadian Research & Education in Arthritis
AbbVie

Completed

Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab (OKINADA) (OKINADA)

Osteoarthritis, Knee

Canada
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Rheumatoid Arthritis

Germany, Italy, Spain, United States, France, Sweden, Greece, Russian Federation, Denmark, Finland, Netherlands, Puerto Rico
Assistance Publique - Hôpitaux de Paris
Abbott

Completed

Efficacy Study of an Anti-Tumor Necrosis Factor (TNF) Alpha Agent in Patients With Hand Osteoarthritis (DORA)

Hand Osteoarthritis

France
Abbott

Completed

Assessment of the Effect of Adalimumab on Response to Influenza Virus and Pneumococcal Vaccines in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Abbott
Eisai Limited

Completed

A Study of Adalimumab in Adult Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Abbott

Completed

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

United States, Argentina, Australia, Austria, Belgium, Canada, Czech Republic, Denmark, France, Germany, Hungary, Israel, New Zealand, Norway, Poland, Portugal, Spain, Switzerland
AbbVie

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA)

United States, Germany, Hungary, Israel, Netherlands, Poland, Puerto Rico
Abbott

Completed

Safety and Efficacy Study of Adalimumab in Adult Chinese Rheumatoid Arthritis Subjects Treated With Methotrexate

Rheumatoid Arthritis

China
Pfizer

Completed

Study Of PF-06410293 And Adalimumab In Healthy Subjects (REFLECTIONS B538-01)

Healthy

United States, Belgium
University Hospital, Geneva

Completed

Adalimumab in Severe and Acute Sciatica (ASAS)

Sciatica

Switzerland
AbbVie (prior sponsor, Abbott)
Eisai Co., Ltd.

Completed

A Study of Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis

Japan
Abbott

Completed

Study of Adalimumab in Subjects With Moderate to Severe Chronic Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Denmark, Germany, Netherlands
Applied Molecular Transport

Completed

Study of the Efficacy and Safety of AMT-101 in Combination With Adalimumab in Subjects With Ulcerative Colitis (MARKET)

Ulcerative Colitis

Georgia, Netherlands, Poland, Ukraine
University of Pennsylvania

Completed

Vascular Inflammation in Psoriasis Trial (The VIP Trial) (VIP)

Cardiovascular Disease | Psoriasis

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Sarilumab and Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (SARIL-RA-MONARCH)

Rheumatoid Arthritis

United States, Chile, Czechia, Germany, Hungary, Israel, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine, Korea, Republic of, United Kingdom
Novartis Pharmaceuticals

Completed

Effect of Secukinumab on Radiographic Progression in Ankylosing Spondylitis as Compared to GP2017 (Adalimumab Biosimilar) (SURPASS)

Ankylosing Spondylitis

Taiwan, Netherlands, United Kingdom, Germany, Korea, Republic of, Israel, United States, Belgium, Greece, Philippines, Russian Federation, Spain, Turkey, Portugal, Mexico, Peru, Denmark, France, Czechia, Australia, Canada, Poland, J... and more
University of Oxford
National Institute for Health Research, United Kingdom; 180 Life Sciences

Completed

The Anti-Freaze-F Study- "Anti-TNF for Treatment of Frozen Shoulder - a Feasibility Study" (Anti-FreazeF)

Frozen Shoulder

United Kingdom
AstraZeneca

Terminated

Evaluation of Efficacy and Safety of Fostamatinib Monotherapy Compared With Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (RA) (OSKIRA -4)

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Poland, Russian Federation, South Africa, United Kingdom, Hungary, Ukraine, Germany, Netherlands, Canada, Slovakia

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