Search clinical trials for: placebo to tocilizumab

Total 60625 results

Nationwide Children's Hospital
Children's Hospital Colorado

Recruiting

ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

Adamantinomatous Craniopharyngioma | Recurrent Adamantinomatous Craniopharyngioma

United States, United Kingdom, Australia, Canada, Germany, Netherlands
Hoffmann-La Roche

Completed

An Extension Study of WA19926 of the Long-Term Safety of Tocilizumab (RoActemra/Actemra) in Patients With Early Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Karoline Krause
Roche Pharma AG

Completed

Tocilizumab in Patients With Schnitzler's Syndrome (TOCISCH)

Schnitzler's Syndrome

Germany
Hoffmann-La Roche

Completed

A Long Term Extension Study of WA19926 (NCT01007435) of Tocilizumab (RoActemra/Actemra) in Participants With Early, Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Brazil
Hoffmann-La Roche

Terminated

An Extension Study to WA19977 in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Russian Federation, Poland
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic DMARDs

Rheumatoid Arthritis

Finland
Hoffmann-La Roche

Completed

A Study of Subcutaneously (SC) Administered Tocilizumab (TCZ) in Participants With Polyarticular-Course Juvenile Idiopathic Arthritis (pJIA) (JIGSAW 117)

Juvenile Idiopathic Arthritis

Spain, Mexico, Germany, United States, Russian Federation, Australia, Italy, Argentina, Brazil, Canada, France, United Kingdom
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

France
Hoffmann-La Roche

Completed

An Extension Long-Term Study of RoActemra/Actemra (Tocilizumab) in Patients With Polyarticular Juvenile Idiopathic Arthritis Who Completed The WA19977 Study

Juvenile Idiopathic Arthritis

Brazil
Hoffmann-La Roche

Completed

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Rheumatoid Arthritis

Belgium, Czech Republic, France, Italy, Spain, Sweden, United Kingdom, Canada, Greece, Ireland, Portugal, Turkey, Netherlands, Denmark, Finland, Germany, Luxembourg, Austria, Switzerland, Poland, Australia, Hungary, Saudi Arabia, Romania and more
Hoffmann-La Roche

Completed

A Study of Tocilizumab as Monotherapy or in Combination With DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

United Arab Emirates, Kuwait, Bahrain, Iran, Islamic Republic of, Qatar
Hoffmann-La Roche

Completed

A Long-term Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

France, Israel, Italy, Hong Kong, Switzerland, Canada, Germany, Mexico, Austria, Thailand, Singapore, Hungary, Bulgaria, Australia, Argentina, Slovakia, Brazil
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Ankylosing Spondylitis Who Have Failed Treatment With NSAIDs

Spondylitis, Ankylosing

Belgium, Czech Republic, France, Germany, Italy, Poland, Spain, United States, Canada, South Africa, United Kingdom, Russian Federation, Australia, Bulgaria, India, Lithuania, Brazil, Slovakia
Hoffmann-La Roche

Completed

Extension Study Evaluating the Safety and Efficacy of Subcutaneous Tocilizumab (RoActemra/Actemra) Administration in Systemic and Polyarticular-Course Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States, Canada, United Kingdom, Brazil, Germany, Italy, Russian Federation, Spain, Australia, France, Mexico, Argentina
Hoffmann-La Roche

Completed

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).

Giant Cell Arteritis

Switzerland
Lahore General Hospital

Unknown

Tocilizumab in COVID-19 Lahore General Hospital (TC19LGH)

SARS-CoV Infection

Pakistan
Hoffmann-La Roche

Terminated

A Long-Term Extension Study to WA19926 (NCT01007435) of Tocilizumab in Participants With Early, Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Poland
Hoffmann-La Roche

Completed

TOSCARA Study: A Study of Subcutaneous Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis Naïve to RoActemra/Actemra Treatment

Rheumatoid Arthritis

Belgium, Luxembourg
Hoffmann-La Roche
Clalit Health Services

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Current Non-Biologic and/or Biologic DMARDS

Rheumatoid Arthritis

Israel
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Early Moderate to Severe Rheumatoid Arthritis Who Completed Study WA19926

Rheumatoid Arthritis

Macedonia, The Former Yugoslav Republic of
Hoffmann-La Roche

Completed

A Study to Provide RoActemra/Actemra (Tocilzumab) to Patients With Multicentric Castleman's Disease Who Demonstrated Benefit From Previous RoActemra/Actemra Treatment

Castleman's Disease

United States
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Turkey
Hoffmann-La Roche

Completed

A Study in Patients With Moderate to Severe Active Rheumatoid Arthritis Comparing Different Infusion Durations of RoActemra/Actemra (Tocilizumab) Treatment

Rheumatoid Arthritis

Denmark, Iceland
Hoffmann-La Roche

Completed

An Extension to Study MA21573, Evaluating Tocilizumab in Patients With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biological DMARDs and/or Anti-tumor Necrosis Factor (TNF) Therapy

Rheumatoid Arthritis

Czech Republic, France, Italy, Spain, United Kingdom, Canada, Portugal, Netherlands, Poland, Australia, Saudi Arabia, Romania, Hungary, Greece
Tang-Du Hospital

Recruiting

Efficacy and Safety of Tocilizumab in the Treatment of Generalized Myasthenia Gravis (tMG)

Myasthenia Gravis, Generalized

China
Centre Hospitalier Régional d'Orléans
Rennes University Hospital

Recruiting

Filling Bone Erosions: a Longitudinal Multicentric HR-pQCT Study of Subcutaneous Tocilizumab in Rheumatoid Arthritis (REPAIR)

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Study of Subcutaneously Administered Tocilizumab in Participants With Systemic Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

United States, Canada, United Kingdom, Brazil, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Australia, France
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs or Anti-TNF

Rheumatoid Arthritis

Saudi Arabia
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Philippines
Hoffmann-La Roche

Completed

A Study of the Efficacy and Safety of Tocilizumab in Adults With Rheumatoid Arthritis.

Rheumatoid Arthritis

Israel
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22762 to Evaluate Safety and Efficacy of Subcutaneous Tocilizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA).

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Long-Term Safety Extension Study of WA19926 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

Germany
Hoffmann-La Roche

Completed

A Prospective Observational Study of Tocilizumab (RoActemra/Actemra) in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Hoffmann-La Roche

Completed

Use of Tocilizumab for Rheumatoid Arthritis (RA) in Daily Routine

Rheumatoid Arthritis

Germany
Genentech, Inc.

Completed

A Long-Term Extension Study of WA22762 and NA25220 of Subcutaneous (SC) Tocilizumab (TCZ) in Moderate to Severe Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.

Rheumatoid Arthritis

United Kingdom
Hoffmann-La Roche

Completed

A Study Comparing Infusion Rates of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs (REMISSION)

Rheumatoid Arthritis

Morocco
Suzhou Municipal Hospital of Anhui Province
Xuanwu Hospital, Beijing

Recruiting

Effect of Interleukin-6 Receptor Inhibition in Patients With Ischemic Stroke Undergoing Endovascular Treatment (IRIS)

Ischemic Stroke | Endovascular Treatment | Interleukin-6

China
Instituto Nacional de Cancerologia de Mexico
Roche Pharma AG

Active, not recruiting

Tocilizumab Treatment in Patients With COVID-19

Sars-CoV2

Mexico
Chugai Pharmaceutical

Completed

Phase III Comparative Study(Open-Label) of MRA for Rheumatoid Arthritis(RA)

Rheumatoid Arthritis
Hoffmann-La Roche

Completed

A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia (MARIPOSA)

COVID-19 Pneumonia

United States
Case Western Reserve University

Completed

AIDS 347: IL-6 Blockade in Treated HIV Infection (IL-6)

HIV Infections

United States
Hoffmann-La Roche

Terminated

Study of RO7515629 in Participants With HLA-G Positive Solid Tumors

Renal Cell Carcinoma | Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Neoplasms | Non-small Cell Lung Cancer

United States
Azienda Unità Sanitaria Locale Reggio Emilia

Terminated

Efficacy of Early Administration of Tocilizumab in COVID-19 Patients

COVID-19 Pneumonia

Italy
Ospedale San Raffaele

Terminated

Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

Italy
Hoffmann-La Roche

Completed

A Study to Evaluate Pharmacokinetics and Safety of Tocilizumab (RoActemra/Actemra) in Participants Less Than 2 Years Old With Active Systemic Juvenile Idiopathic Arthritis (sJIA)

Juvenile Idiopathic Arthritis

Belgium, Canada, United States, Argentina, Poland, Spain, Germany, Hungary
Noema Pharma AG

Recruiting

Basimglurant in Children, Adolescents, and Young Adults With TSC

Tuberous Sclerosis Complex

United States, India, Israel, Turkey, Italy, Poland, Spain, United Kingdom
Alyatec

Completed

Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber

Allergic Rhinitis | Rhinoconjunctivitis | Allergy to Pollen

France

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