Search clinical trials for: Tacrolimus and Sirolimus

Total 272528 results

Kasr El Aini Hospital

Completed

Efficiency of Fractional-Laser Resurfacing Followed by Topical Tacrolimus 0.03% Cream vs Tacrolimus Alone in Vitiligo

Stable Vitiligo
Assiut University

Unknown

The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo

Vitiligo Vulgaris
University of Miami
Wyeth-Ayesrst Pharmaceuticals, Roche Laboratories, and Fujusawa Healthcare...

Completed

Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney Transplantation

Adult Primary Kidney Transplantation

United States
Medical University of South Carolina
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Sirolimus Conversions in African-American Renal Transplant Recipients

Absence; Kidney

United States
Helio Tedesco Silva Junior
Pfizer

Completed

Planned Conversion From TAC to SRL-based Regimen in de Novo Kidney Transplant Recipients

Kidney Transplant

Brazil
Dana-Farber Cancer Institute

Completed

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

Myelodysplastic Syndromes | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Graft Versus Host Disease | Hodgkin's Disease

United States
AZ-VUB
Fund for Scientific Research, Flanders, Belgium; Belgian Government

Terminated

Comparison of Sirolimus Alone With Sirolimus Plus Tacrolimus in Type 1 Diabetic Recipients of Cultured Islet Cell Grafts

Type 1 Diabetes | Islet Transplantation

Belgium
University of Pittsburgh

Terminated

Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity (Sirolimus)

Hypertension
St. Joseph's Healthcare Hamilton

Withdrawn

Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer

Prostate Cancer

Canada
Masaryk University

Unknown

Comparison of Biolimus A9 and Everolimus Drug-Eluting Stents in Patients With ST Segment Elevation Myocardial Infarction (ROBUST)

Coronary Heart Disease | Percutaneous Coronary Intervention

Czech Republic
National Taiwan University Hospital

Unknown

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
University of Miami
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus

Living Donor Kidney Transplants Patients
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients

Kidney Transplantation | Skin Neoplasms

Australia, United States, Canada, New Zealand
National Taiwan University Hospital

Unknown

The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

Kidney Transplantation

Taiwan
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Foundation for Liver Research

Completed

Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus

Liver Disease

Netherlands
Sohag University

Unknown

Effectivness of Topical Tacrolimus Monotherapy in Patients With Vitiligo

Vitiligo | Tacrolimus

Egypt
Biosensors Europe SA

Unknown

BioFreedom QCA Study in CAD Patients (BioFreedomQCA)

Myocardial Infarction | Coronary Artery Disease | Cardiac Death

Spain, Denmark
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

Liver Transplantation

Italy, Belgium, Spain, France, Canada, Germany, United States, United Kingdom, Portugal, Czech Republic, Switzerland, Netherlands
The Korean Society of Blood and Marrow Transplantation
Chonbuk National University Hospital; Samsung Medical Center; Seoul St. Mary's... and other collaborators

Terminated

Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants

Myelodysplastic Syndromes | Leukemia, Myeloid, Chronic-Phase | Acute Leukemia in Remission | Leukemia, Myeloid, Accelerated-Phase

Korea, Republic of
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation

Graft Versus Host Disease | GVHD

United States
University Hospital Schleswig-Holstein
University of Kiel

Completed

Polymorphism of the Cytochrome P450-system in Renal Transplants

Function of Renal Transplant

Germany
Central South University

Unknown

The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant Recipients

Kidney Transplantation

China
University Hospital, Lille
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Islet Allotransplantation With Steroid Free Immunosuppression

Metabolic Diseases | Hypoglycemia | Type 1 Diabetes

France
Yonsei University

Completed

Study to Evaluate the Safety and Efficacy of Extended Release Tacrolimus (Advagraf®) + Sirolimus (Rapamune®), Versus Extended Release Tacrolimus (Advagraf®) + Mycophenolate Mofetil in Kidney Transplant Patients

Kidney Transplant Patients

Korea, Republic of
Translational Research Center for Medical Innovation...
Wakayama Medical University

Completed

OPtical Frequency Domain Imaging vs. INtravascular Ultrasound in Percutaneous Coronary InterventiON (OPINION)

Coronary Artery Disease

Japan
National Cancer Institute (NCI)

Terminated

Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders

Leukemia | Multiple Myeloma | MDS | Non-Hodgkins Lymphoma | Hodgkins Lymphoma

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

Graft Rejection | Kidney Failure

United States, Spain, Canada, Switzerland, Austria, Australia, New Zealand
University of Maryland, Baltimore

Completed

Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients

Bronchiolitis Obliterans | Chronic Rejection of Lung Transplant | Disorder Related to Lung Transplantation | Decreased Immunologic Activity

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients

Kidney Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant Patients

Kidney Transplantation
University of Minnesota

Withdrawn

Kidney Allograft Dysfunction Without Reversible Causes (KADWORC)

Kidney Graft Dysfunction

United States
Terumo Europe N.V.

Completed

Randomized Study to Assess the Effect of ThRombus Aspiration on Flow Area in STEMI Patients (TROFI)

Myocardial Infarction | Coronary Artery Disease | STEMI

Germany, France, Denmark, Netherlands
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Conversion to Sirolimus vs. Continued Use of Calcineurin Inhibitors in Kidney Transplant Recipients

Renal Transplantation
Astellas Pharma Inc

Completed

Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis

Keratoconjunctivitis | Conjunctivitis

Japan
Odense University Hospital

Unknown

Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent (SORT OUT VII)

Coronary Artery Disease | Ischemic Heart Disease

Denmark
Karolinska Institutet

Completed

Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation

Survival | Graft-versus-host Disease

Sweden
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Novartis Pharmaceuticals

Completed

Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients

Liver Transplant Recipient

Belgium, Spain, Germany, Italy, Australia, United States, Netherlands, Ireland, Sweden, Brazil, Colombia, France, Russian Federation, Argentina, Czechia, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients (RAD)

Liver Transplantation

United States, Belgium, Colombia, Spain, Germany, Italy, Australia, Israel, France, Hungary, Netherlands, Argentina, Canada, Ireland, Sweden, Brazil, United Kingdom, Russian Federation, Czech Republic
University of Minnesota
Wyeth is now a wholly owned subsidiary of Pfizer; Roche Pharma AG; Genzyme, a...

Completed

Calcineurin Inhibitor Sparing After Kidney Transplantation (CNI-Sparing)

CNI Side Effects

United States
Hospices Civils de Lyon

Completed

TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients

Kidney Transplantation | Skin Cancer

France
University at Buffalo
Novartis; University of Washington

Completed

Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal

Kidney Transplantation

United States
Translational Research Center for Medical Innovation...
Wakayama Medical University

Completed

OPtical Frequency Domain Imaging Versus INtravascular Ultrasound in Percutaneous Coronary InterventiON - OPINION Imaging

Coronary Artery Disease

Japan
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

Pharmacokinetics of Tacrolimus in Liver Transplantation Patients Treated With Prograf and Modified Release Tacrolimus

Liver Transplantation

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitors Versus Sirolimus in Renal Allograft Recipient

Kidney Transplantation

Taiwan
Hannover Medical School

Unknown

Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant (BKVIRUS)

Virus Diseases | Disorder Related to Renal Transplantation | Immunosuppression Related Infectious Disease

Germany
Heleen Grootjans
Chiesi Farmaceutici S.p.A.

Recruiting

Trial Comparing Immediate Versus Extended Release Tacrolimus; Reducing Calcineurin Inhibitor Related Toxicity in Lung Transplantation Patients (REVOLUTION)

Lung Transplant; Complications

Netherlands
Southern Medical University, China
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern...

Not yet recruiting

Sirolimus-based Immunosuppression Treatment Regimen for Liver Transplantation

Liver Transplantation

China
Pfizer

Terminated

Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients

Atherosclerosis | Kidney Failure

Canada, United States

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