Search clinical trials for: Thymoglobulin®

Total 13969 results

Hadassah Medical Organization

Completed

Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantation

Stem Cell Transplantation | Graft Vs Host Disease

Israel
University Hospital, Basel, Switzerland

Completed

Comparison of ATG to Thymoglobuline in Renal Transplantation

Transplantation, Kidney

Switzerland
European Institute of Oncology
Istituto Clinico Humanitas

Terminated

Allogenic Haematopoietic Cell Transplantation for Patients With Refractory "Triple Negative" Breast Cancer

Breast Cancer

Italy
Nantes University Hospital

Completed

Study of a Reduced-toxicity Myeloablative Conditioning Regimen Using Fludarabine and Full Doses of Intravenous Busulfan in Pediatric Patients Not Eligible for Standard Myeloablative Conditioning Regimens (FB4-PEDIA)

Hematologic Malignancy

France
Gang Chen
Changhai Hospital; First Affiliated Hospital, Sun Yat-Sen University; The First... and other collaborators

Completed

Pediatric Induction Therapy in Kidney Transplantation (PINK)

Kidney Transplant Rejection | Pediatric Kidney Disease

China
University of California, Los Angeles
Genzyme, a Sanofi Company

Withdrawn

Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation

Lung Transplant

United States
European Society for Blood and Marrow Transplantation
Genzyme, a Sanofi Company

Completed

Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic Anaemia (RATGAA07)

Aplastic Anemia

Switzerland, United Kingdom, Germany, Italy, France, Saudi Arabia
Chinese PLA General Hospital

Recruiting

Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT

aGVHD | cGVHD

China
Barbara Ann Karmanos Cancer Institute

Completed

Tacrolimus and Thymoglobulin, as GvHD Prophylaxis in Patients Undergoing Related Donor HCT

Hematological Malignancies

United States
Genzyme, a Sanofi Company

Terminated

Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Syndrome (RISE)

Myelodysplastic Syndrome (MDS)

Germany, United Kingdom, France, Netherlands
King Faisal Specialist Hospital & Research Center

Completed

Prospective Phase II Study of Rabbit Antithymocyte Globulin (ATG, Thymoglobuline®, Genzyme) With Ciclosporin for Patients With Acquired Aplastic Anaemia

Acquired Aplastic Anaemia
Memorial Sloan Kettering Cancer Center
Pediatric Brain Tumor Consortium

Terminated

A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)

United States
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Terminated

Study of Antithymocyte Globulin for Treatment of New-onset T1DM (START)

New-onset Type 1 Diabetes Mellitus

United States
M.D. Anderson Cancer Center
Genzyme, a Sanofi Company

Terminated

Thymoglobulin (ATG) Dose Finding Study

Graft vs Host Disease

United States
Nantes University Hospital

Completed

Study of a Reduced-toxicity "Submyeloablative" Conditioning Regimen Prior to Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies (ITT 08-01)

Hematological Malignancies

France
Washington University School of Medicine
Genzyme, a Sanofi Company

Completed

A Phase I Study Of Thymoglobulin In Patients With Relapsed Or Refractory Multiple Myeloma

Relapsed Or Refractory Multiple Myeloma

United States
Institut Paoli-Calmettes
Sanofi

Not yet recruiting

PROPHYLAXIS OF GVH IN ELDERLY PATIENTS RECEIVING HAPLOIDENTICAL ALLOGENIC HEMATOPOIETIC STEM CELL TRASNPLANTATION USE OF A LOW DOSE ANTI-LYMPHOCYTIC SERUM (CASPER)

Hematological Malignancy
University Hospital, Lille
Erasme University Hospital

Completed

Daclizumab Versus Thymoglobulin in Renal Transplant Recipients With High Immunological Risk (TAXI)

Renal Transplantation

France
University of Cincinnati
Genzyme, a Sanofi Company

Completed

Prospective Pilot Study of Pre-Transplant Thymoglobulin Administration in Living Donor Renal Transplant Recipients

Renal Transplant Rejection | Transplants and Implants

United States
Peking University People's Hospital

Completed

Anti-thymocyte Globulins for Graft-versus-host Disease Prophylaxis

Leukemia, GVHD, ATG, Transplantation

China
University Hospital, Brest

Unknown

Influence of Thymoglobuline on Phenotypic and Functional Profiles of B Lymphocytes in Renal Transplant Recipients (THYMO B)

Renal Transplant

France
University Hospital Tuebingen

Terminated

Haploidentical Stem Cell Transplantation With CD3/CD19 Depletion and Reduced Intensity Conditioning in Patients With Acute Leukemia (CD3/CD19 Haplo)

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia

Germany
Institut Paoli-Calmettes
Agence de La Biomédecine

Completed

Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases (BX-PK)

Hematological Diseases

France
Hospices Civils de Lyon

Recruiting

Thymoglobulin® Pharmacokinetics in Patients Undergoing Hematopoietic Stem Cell Transplantation (PHASAL-GA)

Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy

France
National Institute of Allergy and Infectious Diseases...

Completed

Antibody and Delayed Cyclosporine Versus Initial Cyclosporine Alone in Patients Receiving Kidney Transplants

Kidney Transplantation | Chronic Allograft Nephropathy

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

Severe Aplastic Anemia

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Unknown

ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors

Lymphoblastic Lymphoma

China
The Hospital for Sick Children

Terminated

Pharmacokinetics of Thymoglobulin in Paediatric Haematopoietic Stem-cell Transplants

Metabolic Disease | Genetic Disorder | Malignancy

Canada
University of Illinois at Chicago

Recruiting

Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Columbia University

Completed

Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia (AML/MDS/JMML)

Juvenile Myelomonocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Lahey Clinic
Brigham and Women's Hospital

Completed

Low Dose Thymoglobin in Renal Transplant Patients

Acute Renal Failure

United States
Masonic Cancer Center, University of Minnesota

Terminated

Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant

Cancer

United States
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Memorial Sloan Kettering Cancer Center

Terminated

TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors

Non-Malignant Hematologic Disorders

United States
Genzyme, a Sanofi Company

Completed

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

Cadaveric Donor Renal Transplantation | Acute Renal Allograft Rejection | Induction Therapy

United States, France, Spain, United Kingdom, Germany
Genzyme, a Sanofi Company

Completed

A Study to Evaluate the Effect of Thymoglobulin and Reduced Doses of Steroids to Prevent Renal Transplant Rejection

Graft Rejection | Renal Transplantation

United States
University of Oxford
Genzyme, a Sanofi Company; Oxford University Hospitals NHS Trust

Unknown

Thymoglobulin Induction in Kidney Transplant Recipients (TIKT)

Kidney Transplantation | Ischemia-Reperfusion Injury

United Kingdom
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Kidney Transplantation | Primary Renal Allograft Candidate

United States
Genzyme, a Sanofi Company

Completed

Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) or Acute Myelogenous Leukemia (AML) Receiving a Stem Cell Transplant

Acute Myelogenous Leukemia (AML) | Acute Lymphocytic Leukemia (ALL) | Graft vs. Host Disease (GvHD)

United States, Canada
Shanghai General Hospital, Shanghai Jiao Tong University...
Ruijin Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine and other collaborators

Completed

The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia

Severe Aplastic Anemia

China
Ospedale San Raffaele
Juvenile Diabetes Research Foundation

Completed

Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation (ECIT-1)

Type 1 Diabetes

Italy, Switzerland
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Clinical Trials in Organ Transplantation

Completed

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Kidney Transplant Recipients | Living-Donor Kidney Transplant

United States
St. Jude Children's Research Hospital

Active, not recruiting

Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)

Severe Combined Immunodeficiency

United States
Maimónides Biomedical Research Institute of Córdoba

Completed

Kinetic Study of CD8+ CMV-specific Cellular Immunity in Renal Transplant Patients After Receiving Thymoglobulin

Renal Transplant Infection

Spain
Nagoya University

Unknown

Randomised Study Comparing Different Dosages of Rabbit ATG in Patients With SAA

Acquired Aplastic Anemia.

Japan
Vastra Gotaland Region
Oslo University Hospital; Helsinki University Central Hospital; Skane University... and other collaborators

Active, not recruiting

Clinical Study Evaluating Two Treatment Protocols for Immunosuppressive Drugs. Looking at 3-year Incidence of CLAD. (ScanCLAD)

Lung Transplantation | Allografts

Norway, Sweden, Finland, Denmark
University Hospital, Clermont-Ferrand

Unknown

Allogeneic Hematopoietic Stem Cell Transplantation (RICE)

Hematologic Neoplasms | Solid Tumors

France
Hospital Geral de Fortaleza

Unknown

Efficacy and Safety of Rabbit Antithymocyte Globulin 3mg/kg in Kidney Transplant Patients Under Steroid-free and CNI Minimization Maintenance Immunosuppressive Regimen

Thymoglobulin Dose

Brazil
Asan Medical Center

Unknown

Thymoglobulin Induction Therapy in Kidney Transplantation (6mg/kg vs 4mg/kg)

Kidney Failure
Washington University School of Medicine

Terminated

Single Dose Thymoglobulin for Induction in Adult Renal Allograft Recipients

Kidney Transplantation

United States

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