Search clinical trials for: Ticagrelor Aspirin

Total 1666 results

HonorHealth Research Institute
Boston Scientific Corporation

Active, not recruiting

SYNergy Stent® System Implantation With Mandatory Intra-VascularUltra-Sound Guidance and Dual Anti-Platelet Therapy (SYNIVUS-DAPT)

Coronary Artery Disease | Atherosclerosis | Stent Placement

United States
University of Florida
AstraZeneca

Completed

Impact of Ticagrelor Re-load on Pharmacodynamic Profiles

Coronary Artery Disease

United States
SFJ Pharmaceuticals, Inc.

Completed

Phase 2B Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old

Healthy

United States, Canada
David Antoniucci
AstraZeneca; A.R. CARD Onlus Foundation

Completed

Mojito Study (Mashed Or Just Integral Pill of TicagrelOr ? )

Acute Coronary Syndrome | Adverse Reaction to Antiplatelet Agent

Italy, Greece
Aswan University Hospital

Unknown

Aspirin for Prevention of Preeclampsia

Preeclampsia

Egypt
Centro Hospitalario La Concepcion

Recruiting

Pharmacodynamic Evaluation of Antiplatelet Effect of Swallowing Versus Chewing Ticagrelor in Patients With Acute Coronary Syndrome (TICA-MASTICA)

Acute Coronary Syndrome

Mexico
Sheba Medical Center

Completed

Chewing Versus Traditional Oral Administration of Ticagrelor in STEMI Patients

ST Elevation Myocardial Infarction | Acute Coronary Syndromes

Israel
Genshan Ma
Zhongda Hospital

Completed

Safety of "Ticagrelor+ Warfarin"in Comparison With "Clopidogrel+Aspirin+Warfarin"

Coronary Artery Disease | Atrial Fibrillation

China
Hospital de Meixoeiro

Completed

Platelet Reactivity After TAVI: A Multicenter Pilot Study (REAC-TAVI)

Transcatheter Aortic Valve Replacement | Transcatheter Aortic Valve Implantation | Severe Aortic Valve Stenosis

Spain
Cairo University

Completed

Testing P2Y12 Platelet Inhibitors Generics Beyond Bioequivalence

Cardiovascular Diseases | Acute Coronary Syndrome

Egypt
University of Florida
The Medicines Company

Completed

In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients

Coronary Artery Disease

United States
Weill Medical College of Cornell University
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

One-Month DAPT in CABG Patients (ODIN)

Chronic Coronary Disease

United States, Austria, Canada, Germany, Sweden
University of Karachi
PharmEvo Private Limited., Pakistan

Completed

Bioequivalence Study of Anplag® 90mg (Ticagrelor) Tablet & Brilinta® 90 mg (Ticagrelor) Tablet in Healthy Adult Male Pakistani Subjects Under Fasting Condition (BE)

Healthy Individuals

Pakistan
University of Patras

Completed

OraL Crushed and dIspersed Ticagrelor 180mg Compared to Whole Tablets of eQUal Dose in STEMI Patients unDergoing Primary PCI: a Pharmacokinetic/Pharmacodynamic Study (the LIQUID Study) (LIQUID)

ST Elevation Myocardial Infarction

Greece
AstraZeneca

Completed

Study to Investigate if the Uptake of Ticagrelor Into the Body Differs Depending on Method of Administration.

Bioavailability Heathy Volunteers

United Kingdom
Federico II University

Completed

Platelet Aggregation in Diabetic Patients With Acute Coronary Syndrome Treated With Different Doses of Aspirin (DIABE-ASACS)

Diabetes Mellitus | Acute Coronary Syndrome

Italy
Azienda Ospedaliero Universitaria di Sassari
AstraZeneca

Completed

Ticagrelor Administered as Standard Tablet or Orodispersible Formulation (TASTER)

ST Elevation Myocardial Infarction | NSTEMI - Non-ST Segment Elevation MI

Italy
Arkansas Heart Hospital
University of Alabama at Birmingham; The University of Texas Health Science...

Terminated

Ticagrelor and Peripheral Arterial Disease

Peripheral Arterial Disease

United States
AstraZeneca

Completed

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS)

Myocardial Infarction | Stroke | Atherothrombosis | Cardiovascular Death

Sweden, United States, Australia, Brazil, Bulgaria, Czech Republic, France, Italy, Korea, Republic of, Peru, Poland, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Philippines, China, Hungary, Romania, U... and more
Medical University of Vienna

Unknown

High "on Treatment" Platelet Reactivity in the Intensive Care Unit

Critical Illness

Austria
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis (RIISC-THETIS)

Myocardial Infarction | Stroke | Atherosclerosis | Cerebral Infarction | Stroke, Ischemic | Cardiac Disease | Coronary Syndrome | TIA

France
AstraZeneca

Completed

A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus (THEMIS)

Diabetes Mellitus, Type 2

United States, Austria, Belgium, Canada, Denmark, France, Germany, Italy, Netherlands, Spain, United Kingdom, Czechia, Hungary, Thailand, Turkey, Vietnam, Korea, Republic of, Brazil, Peru, Philippines, Poland, China, Japan, Taiwan, Hong... and more
Hospital Israelita Albert Einstein

Recruiting

Platelet Sub-study of the Neomindset Trial

Acute Coronary Syndrome

Brazil
Bio-innova Co., Ltd

Not yet recruiting

Ticagrelor Tablets 90 mg Relative to Originator Ticagrelor Tablets 90 mg (TIC-025-23)

Healthy Subjects
First Affiliated Hospital of Harbin Medical University

Unknown

Low-dose Ticagrelor in Chinese ACS Patients Undergoing PCI

Acute Coronary Syndrome

China
University Magna Graecia

Completed

Platelet Aggregation During the Shift From Clopidogrel to Ticagrelor (SHIFT-OVER)

Acute Coronary Syndrome

Italy
Dong-A University

Recruiting

Ticagrelor De-escalation Strategy in East Asian Patients With AMI

Acute Myocardial Infarction

Korea, Republic of
The Third Xiangya Hospital of Central South University

Completed

Study on the Registration of Coronary Heart Disease Patients Undergoing PCI

Coronary Heart Disease

China
University Hospital, Toulouse

Completed

TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement (TIRATROP)

Atherosclerosis

France
Massachusetts General Hospital
AstraZeneca

Withdrawn

Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study

Coronary Artery Disease | Acute Coronary Syndrome

United States
First Affiliated Hospital of Harbin Medical University

Unknown

Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACS

Non ST Segment Elevation Acute Coronary Syndrome

United States
Icahn School of Medicine at Mount Sinai
AstraZeneca

Completed

Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention (TWILIGHT)

Cardiovascular Disease | Interventional Cardiology

United States
Hamilton Health Sciences Corporation

Unknown

Reversal of the Antiplatelet Effects of Ticagrelor in Combination With Aspirin, Using Normal Platelets (REVSTARTS)

Aspirin | Platelet Dysfunction Due to Drugs | Ticagrelor | Transfusion

Canada
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
University of Florida
Janssen, LP

Completed

Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease (SWAP-AC)

Coronary Artery Disease

United States
AstraZeneca

Completed

[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] (SOCRATES)

Acute Ischaemic Stroke | Transient Ischaemic Attack

Sweden, United States, Australia, Brazil, Bulgaria, France, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Turkey, Vietnam, Germany, Philippines, China, Hungary, Romania, Ukraine, Hong Kong, Argentina, Bel... and more
Yong Huo

Completed

Arachidonic Acid-induced Platelet Aggregation Rate in Patients With Stable CAD Treated With Ticagrelor Monotherapy

Coronary Heart Disease

China
Uniformed Services University of the Health Sciences
National Institutes of Health (NIH)

Withdrawn

Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in Subacute TBI (TBI-EPO)

Traumatic Brain Injury

United States
Shanghai Tong Ren Hospital
Fudan University; Shanghai Jiao Tong University School of Medicine

Recruiting

A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients (TIGER)

Acute Coronary Syndrome | Coronary Stent Implantation

China
Collegium Medicum w Bydgoszczy

Completed

Effectiveness of Lower Maintenance Dose of Ticagrelor Early After Myocardial Infarction (ELECTRA) Pilot Study

Myocardial Infarction

Poland
First Affiliated Hospital of Harbin Medical University

Unknown

Safety and Efficacy of Low-dose Ticagrelor in Chinese Patients With Stable Coronary Artery Disease

Coronary Artery Disease

United States
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca

Completed

STEEL Percutaneous Coronary Intervention (STEEL-PCI)

Coronary Artery Disease

United Kingdom
University of California, San Diego
Janssen Biotech, Inc.; The Organization of Teratology Information Specialists

Recruiting

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

Psoriasis | Pregnancy | Crohn Disease | Psoriatic Arthritis

United States
Sheri Kashmir Institute of Medical Sciences

Completed

Neuroprotective Role of Erythropoietin in Perinatal Asphyxia

Perinatal Asphyxia

India
National Institute of Allergy and Infectious Diseases...

Completed

Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable Immunodeficiency

CVID Enteropathy | Gastrointestinal Inflammation Associated With CVID

United States
The First Affiliated Hospital with Nanjing Medical...

Unknown

the Efficacy and Safety of Indobufen and Low-dose Aspirin in Different Regimens of Antiplatelet Therapy

Coronary Atherosclerosis

China
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm (TIC-TAC)

Cerebral Aneurysm

France
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Seoul National University Hospital
CKD Pharmaceutical Limited

Completed

Efficacy and Tolerability of Clopidogrel Resinate and Clopidogrel Bisulfate in Patients With Coronary Heart Disease (CHD) or CHD Equivalents

Coronary Heart Disease
AstraZeneca

Completed

Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects

Pharmacokinetics | Bioequivalence | Healthy Japanese Subjects

United Kingdom

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