Search clinical trials for: Treg cell infusion

Total 14000 results

Laura Johnston
National Institutes of Health (NIH)

Completed

Phase 1 Infused Donor T Regulatory Cells in Steroid Dependent/Refractory Chronic GVHD

Graft Versus Host Disease | Allogeneic Hematopoietic Cell Transplant Recipient

United States
King's College London
Imperial College London; Medical Research Council; Guy's and St Thomas' NHS Foundation... and other collaborators

Unknown

Treg Immunotherapy in Crohn's Disease (TRIBUTE)

Crohn Disease
Mario Arpinati
European Commission

Recruiting

Multiple Donor Treg DLI for Severe Refractory Chronic GVHD (TREG2015001)

Chronic Graft Versus Host Disease

Italy
Masonic Cancer Center, University of Minnesota

Terminated

Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies

Follicular Lymphoma | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Burkitt Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Acute Myelogenous Leukemia | Mantle-Cell Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Small... and other conditions

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS (NKAML)

Adult Acute Myeloid Leukemia in Remission

Italy
University of Liege

Completed

Mesenchymal Stem Cell Infusion as Prevention for Graft Rejection and Graft-versus-host Disease

Hematological Malignancies

Belgium
H. Lee Moffitt Cancer Center and Research Institute

Completed

Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

Graft Versus Host Disease

United States
Stanford University
Northwestern University; California Institute for Regenerative Medicine (CIRM)

Recruiting

TLI, TBI, ATG & Hematopoietic Stem Cell Transplantation and Recipient T Regs Therapy in Living Donor Kidney Transplantation

Living Donor Kidney Transplantation

United States
CARsgen Therapeutics Co., Ltd.

Active, not recruiting

Clinical Trial to Evaluate Zevor-cel (CT053) in Patients With Relapsed and/or Refractory Multiple Myeloma (LUMMICAR STUDY 2)

Multiple Myeloma

United States, Canada
St. Jude Children's Research Hospital
Wayne State University; Drexel University

Completed

Stromal Therapy of Osteodysplasia After Allogeneic Bone Marrow Transplantation

Osteodysplasia

United States
UPECLIN HC FM Botucatu Unesp
Laboratório de Genética Humana e Terapia Celular, Unesp - Assis; Instituto...

Completed

Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease (COPD-01)

Chronic Obstructive Pulmonary Disease | Pulmonary Emphysema

Brazil
Southwest Hospital, China

Unknown

By Using Adoptive Transfer of Autologous NK Cells to Prevent Recurrence of Hepatocellular Carcinoma After Curative Therapy

Hepatocellular Carcinoma

China
American CryoStem Corporation

Active, not recruiting

ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion

Post-Concussion Syndrome

United States
University of California, San Francisco

Completed

Treg Adoptive Therapy for Subclinical Inflammation in Kidney Transplantation (TASK)

Late Complication From Kidney Transplant

United States
Leiden University Medical Center

Completed

Mesenchymal Stem Cells and Subclinical Rejection (Measure)

Organ Transplantation

Netherlands
Mitchell Horwitz, MD

Completed

Naive T-Cell Depleted DLI Following Allo Stem Cell Transplant

Hematological Malignancies

United States
Nanjing Medical University
University of Minnesota

Unknown

Safety Study of Using Regulatory T Cells Induce Liver Transplantation Tolerance (Treg)

Chronic Rejection of Liver Transplant

China
Jianming Tan

Unknown

Mesenchymal Stem Cell for Osteonecrosis of the Femoral Head

Osteochondritis of the Femoral Head

China
Baylor College of Medicine
University of Texas, Southwestern Medical Center at Dallas

Completed

Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation

Leukemia | Cancer

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Recruiting

CAR - γ δ T Cells in the Treatment of Relapsed and Refractory CD7 Positive T Cell-derived Malignant Tumors

CAR | Malignant Tumors

China
Hospital Universitario Dr. Jose E. Gonzalez

Suspended

Autologous Stem Cells in Pediatric Patients With Dilated Cardiomyopathy

Cardiomyopathy, Dilated

Mexico
Andrews Research & Education Foundation
BREG, Inc

Completed

Efficacy Study of an Unloading Brace for Knee Osteoarthritis

Osteoarthritis of the Knee

United States
The University of Texas Health Science Center,...
United States Department of Defense; U.S. Army Medical Research and Development...

Active, not recruiting

Autologous Stem Cell Study for Adult TBI (Phase 2b)

TBI (Traumatic Brain Injury) | Brain Injuries, Traumatic | Brain Injuries, Acute

United States
Everett Meyer
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Acute Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukemia (ALL) | Myeloid Leukemia, Chronic | Myeloproliferative Syndrome

United States
LaTonya J. Hickson

Active, not recruiting

Stem Cell Therapy for Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Chronic Kidney Diseases | Diabetes Mellitus, Type 1 | Diabetic Nephropathies

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias

Lymphoma | Leukemia

United States
The University of New South Wales

Completed

Faecal Microbiota Transplantation in Ulcerative Colitis (FOCUS)

Ulcerative Colitis | Inflammatory Bowel Disease

Australia
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Assisi Foundation

Completed

Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia

Lymphoblastic Leukemia, Acute

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Recruiting

CAR-T CD19/CD20 for Patients With Advanced CD19/CD20+ B Cell Line Recurrent or Refractory Hematological Malignancies

CAR

China
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis

Neutropenic Enterocolitis | Myeloablative Chemotherapy Induced Bone Marrow Aplasia

Russian Federation
Xiaoyu Zhu
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

RD13-02 CAR-T Cell Injection for Patients With r/r CD7+ T-ALL/T-LBL

Neoplasms | Hematologic Diseases | Hematologic Neoplasms

China
He Huang
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

CD7 CAR-T for Patients With r/r CD7+ T-ALL/T-LBL

Neoplasms | Neoplasms by Site | Hematologic Diseases | Hematologic Neoplasms

China
Talaris Therapeutics Inc.

Withdrawn

Allogeneic Stem Cell Transplantation for the Treatment of Multiple Sclerosis

Multiple Sclerosis
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First Affiliated Hospital of Soochow University

Unknown

γδT Cell Infusion to Prevent Relapsed/Refractory Leukemia Rescue Relapse (γδT)

Leukemia, B-cell

China
National Institute of Allergy and Infectious Diseases...

Completed

White Blood Cell Infusions to Treat HIV Infection

Acquired Immunodeficiency Syndrome | HIV Infection

United States
Kai Lin Xu，MD
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

Research Development（RD）13-02 Chimeric Antigen Receptor(CAR) -T Cell Injection for Patients With r/r Cluster Of Differentiation 7（CD7）+ T-Acute Lymphoblastic Leukemia(ALL)/T-Lymphoblastic Lymphoma(LBL) /Acute Myelogenous Leukemia(AML)

Neoplasms | Hematologic Diseases | Hematologic Neoplasms

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Clinical Study of Anti-CD1a CAR-T in the Treatment of R/R Acute T-lymphoblastic Leukemia/Lymphoblastic Lymphoma

Acute T-lymphoblastic Leukemia | Acute T-lymphoblastic Lymphoma

China
He Huang

Recruiting

A Study of RD14-01 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B-cell Lymphoma

China
Massachusetts General Hospital
Dana-Farber Cancer Institute; University of Regensburg

Completed

Infusion of T-Regulatory Cells in Kidney Transplant Recipients (The ONE Study)

Kidney Failure, Kidney Transplant

United States
Talaris Therapeutics Inc.
Duke University

Terminated

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

Niemann-Pick Disease | Alpha-mannosidosis | Tay Sachs Disease | Sandhoff Disease | Metachromatic Leukodystrophy (MLD) | Hurler-Scheie Syndrome | Hurler Syndrome (MPS I) | Hunter Syndrome (MPS II) | Sanfilippo Syndrome (MPS III) | Krabbe Disease (Globoid Leukodystrophy) | Adrenoleukodystrophy (ALD and AMN) | Pelizaeus...

United States
He Huang

Completed

RD13-01 for Patients With r/r CD7+ T/NK Cell Hematologic Malignancies

Hematologic Malignancies

China
Cedars-Sinai Medical Center
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI); National... and other collaborators

Completed

CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction (CADUCEUS)

Ventricular Dysfunction | Recent Myocardial Infarction

United States
Christian Medical College, Vellore, India

Unknown

Evaluation of the Role of Mesenchymal Stem Cells in the Treatment of Graft Versus Host Disease

Graft vs Host Disease

India
Henan Cancer Hospital
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

RD13-02 for Patients With r/r CD7+ T Cell Hematologic Malignancies

Hematologic Malignancies

China
MEI HENG
Nanjing Bioheng Biotech Co., Ltd.

Recruiting

Research Development13(RD13)-02 Cell Injection in Patients With Relapsed or Refractory Cluster Of Differentiation 7(CD7)-Positive Hematological Malignancies

Neoplasms | Neoplasms by Site | Hematologic Diseases | Hematologic Neoplasms

China
Memorial Sloan Kettering Cancer Center

Withdrawn

A Phase I Trial of Donor- Derived 19-28z CAR T Cells Following Allogeneic Transplant for the Treatment of CD19 Malignancies

Lymphoma | Lymphoma, B-Cell | Leukemia

United States
Okayama University
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

Completed

Cardiac Progenitor Cell Infusion to Treat Univentricular Heart Disease (PERSEUS)

Hypoplastic Left Heart Syndrome | Single Right Ventricle | Single Left Ventricle

Japan
Min Xiang

Unknown

RD13-01 for Patients With r/r CD7+ T-ALL/T-LBL

T-lymphoblastic Lymphoma | T Acute Lymphoblastic Leukemia

China
University Hospital, Antwerp

Unknown

Intracoronary Infusion of BM-Derived Mononuclear Cells in Patients With Large Acute Myocardial Infarction

Myocardial Infarction

Belgium
Fondazione Policlinico Universitario Agostino Gemelli...
Ministry of Health, Italy

Terminated

Haploidentical Stem Cell Transplant With or Without NK Cell Infusion in AML and MDS (Bigeminy)

Acute Myeloid Leukemia | Myelodysplasia

Italy

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