Search clinical trials for: Vedolizumab Placebo

Total 53668 results

Takeda

Completed

A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants

Healthy Volunteers

United States
University of Calgary

Not yet recruiting

VERIFY: Vedolizumab for the Prevention of Immune Checkpoint Inhibitor Related Diarrhea or Colitis in Patients With Cancer

Cancer | Cancer Metastatic
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Crohn's Disease (CD)

United States, Australia, Israel, Belgium, Hungary, Canada, China, Croatia, Czechia, Greece, Italy, Japan, Korea, Republic of, Poland, United Kingdom, Lithuania, Slovakia, Spain
University Medical Center Groningen

Completed

Using Vedolizumab-800CW to Gain Insight Into Local Drug Distribution and Mucosal Target Cells in IBD Patients (VISION)

Crohn Disease | Colitis, Ulcerative

Netherlands
Millennium Pharmaceuticals, Inc.

Completed

Long Term Safety of Vedolizumab (MLN0002) in Patients With Ulcerative Colitis and Crohn's Disease

Crohn's Disease | Ulcerative Colitis

Canada
Washington University School of Medicine

Active, not recruiting

Defining Predictors of RT Response to Vedolizumab in IBD

Crohn Disease of Small Intestine

United States
Marc Schwartz
Takeda

Withdrawn

Vedolizumab Post Op Study

Crohn's Disease

United States
Takeda

Completed

A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants

Healthy Volunteers

United States
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. (MANDARA)

Eosinophilic Granulomatous Vasculitis

United States, Canada, France, Italy, Israel, United Kingdom, Japan, Germany, Belgium
Takeda

Recruiting

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis

Belgium, Australia, Israel, United States, Hungary, Korea, Republic of, China, Canada, Croatia, Italy, Poland, Slovakia, United Kingdom, Japan, Greece
Hospitales Universitarios Virgen del Rocío
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Unknown

Vedolizumab Treatment in HIV-Infected Subjects Without Previous Antiretroviral Therapy

HIV Infections

Spain
Millennium Pharmaceuticals, Inc.

Completed

Study of Vedolizumab Following Multiple Intravenous Doses in Patients With Ulcerative Colitis

Ulcerative Colitis
Takeda

Recruiting

Specified Drug-Use Survey on Vedolizumab for IV Infusion 300 mg [Crohn's Disease]

Crohn's Disease

Japan
GlaxoSmithKline

Completed

Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Argentina, Germany, Japan, Romania, Ukraine, Chile, Korea, Republic of, Taiwan, Netherlands, United Kingdom, Canada, Denmark, Australia, Slovakia
Helsinki University Central Hospital

Recruiting

Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) (AirGOs-biol)

Chronic Rhinosinusitis With Nasal Polyps | Asthma, Aspirin-Induced

Finland
GlaxoSmithKline
PPD

Active, not recruiting

Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

Pulmonary Disease, Chronic Obstructive

United States, Australia, Argentina, Canada, France, Germany, Japan, Poland, Spain, Hungary, Belgium, Netherlands, Israel, Mexico, Austria, Korea, Republic of, China, Greece, Denmark, India, Sweden, Taiwan, United Kingdom, Italy, Brazil, New... and more
GlaxoSmithKline

Completed

Study to Evaluate Efficacy and Safety of Mepolizumab for Frequently Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients

Pulmonary Disease, Chronic Obstructive

United States, Australia, Canada, France, Poland, Russian Federation, Spain, Estonia, Belgium, Peru, Sweden, Greece, Mexico, Norway, Italy, Czechia
Ottawa Hospital Research Institute
CHEO Research Institute; Nebraska Centre for Substance Abuse Research

Recruiting

Vedolizumab Treatment in Antiretroviral Drug Treated Chronic HIV Infection (HAVARTI)

HIV-infection/AIDS

Canada
Alimentiv Inc.
Takeda

Not yet recruiting

VOICE-Early Response to Vedolizumab and Ustekinumab in Participants With Crohn's Disease: A Prospective Observational Study (VOICE)

Crohn's Disease
GlaxoSmithKline

Completed

Efficacy and Safety Study of Mepolizumab Adjunctive Therapy in Participants With Severe Eosinophilic Asthma on Markers of Asthma Control

Asthma

United States, Argentina, Canada, France, Netherlands, Spain, Ukraine, Bulgaria, Estonia, Belgium, Peru, Russian Federation, Germany, Greece, Czechia, Italy, United Kingdom, Norway, Slovakia
GlaxoSmithKline

Completed

Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Korea, Republic of, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
University of North Carolina, Chapel Hill
Northwestern University; GlaxoSmithKline; University of Utah; MNGI Digestive Health...

Completed

Mepo for Eosinophilic Esophagitis (EoE) Study

Eosinophilic Esophagitis | EoE

United States
ANRS, Emerging Infectious Diseases
Imperial College London; University College, London; Fred Hutchinson Cancer Center and other collaborators

Terminated

An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection (EHVAT01)

HIV-1-infection

Switzerland, United Kingdom
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Takeda; Mauna...

Terminated

Development of a Biomarker of Efficacy of Vedolizumab (EnTyvio®) in Patients With ulcErative ColiTis (DETECT) (DETECT)

ULCERATIVE COLITIS

France
University of Leicester
GlaxoSmithKline

Active, not recruiting

Mepolizumab for COPD Hospital Eosinophilic Admissions Pragmatic Trial (COPD-HELP)

Eosinophilia | COPD

United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study (MEPOREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Maruho Co., Ltd.

Active, not recruiting

An Open-label, Phase 2 Study to Assess the Efficacy and Safety of Nemolizumab in Subjects With Systemic Sclerosis

Systemic Sclerosis

Japan
King's College Hospital NHS Trust

Active, not recruiting

Study for Children & Adolescent With Severe Asthma With an Eosinophilic Phenotype Treated With Mepolizumab (CASAM)

Asthma in Children

United Kingdom
University Hospital, Montpellier

Completed

Nation-wide Health Resource Consumption and Costs Associated With Mepolizumab (Resala)

Asthma

France
GlaxoSmithKline

No longer available

This Record Contains Information About the Mepolizumab Compassionate Use (CU) Product Activities: 104317: CU and Long-Term Access Study of Mepolizumab in HES. 201956:A Long-term Access Programme for Subjects With Severe Asthma 112562: Expanded Access for Patients With Hypereosinophilic

Hypereosinophilic Syndrome
GlaxoSmithKline

Completed

A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622

Hypereosinophilic Syndrome

United States, Poland, Spain, France, Belgium, Germany, Argentina, Russian Federation, Mexico, Italy, Brazil, United Kingdom, Romania
University Hospital, Grenoble

Completed

Effect of Mepolizumab on Decrease of Systemic Corticosteroids in Patients With Severe Eosinophilic Asthma (Mepolizumab)

Asthma; Eosinophilic

France
GlaxoSmithKline

Completed

An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Oesophagitis In Adult Patients

Oesophagitis, Eosinophilic

Switzerland
Millennium Pharmaceuticals, Inc.

Completed

Phase 2 Study of the Safety and Efficacy of LDP-02 in Mildly to Moderately Active Crohn's Patients

Crohn's Disease
University Hospital Southampton NHS Foundation...
GlaxoSmithKline

Not yet recruiting

Evaluation of Volatile Organic Compounds in Mepolizumab Therapy (EVOC4M)

Asthma; Eosinophilic

United Kingdom
GlaxoSmithKline

Completed

MEA112997 Open-label Long Term Extension Safety Study of Mepolizumab in Asthmatic Subjects

Asthma

United States, Argentina, Australia, France, Germany, Poland, Romania, Russian Federation, Canada, Chile, Korea, Republic of, Ukraine, United Kingdom
Second Affiliated Hospital, School of Medicine,...

Recruiting

Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis

Ulcerative Colitis

China
GlaxoSmithKline
BioClinica, Inc.; Signant Health

Completed

Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) (MERIT)

Nasal Polyps

Russian Federation, Japan, China
Johns Hopkins University
GlaxoSmithKline

Recruiting

The Role of IL5 in Epithelial Cell Integrity

Chronic Rhinosinusitis (Diagnosis) | Chronic Rhinosinusitis With Nasal Polyps

United States
Istituti Clinici Scientifici Maugeri SpA

Recruiting

Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP.

Asthma | Nasal Polyps | Sinusitis Chronic

Italy
Mayo Clinic
GlaxoSmithKline

Active, not recruiting

Mepolizumab for the Treatment of Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

United States
Mayo Clinic
GlaxoSmithKline

Withdrawn

Mepolizumab for Eosinophilic Fasciitis

Eosinophilic Fasciitis
Centre Hospitalier Universitaire de Saint Etienne
Takeda; Theradiag

Terminated

Value of Pharmacokinetic Assays in the Prediction of Induction and Maintenance Therapeutic Response in Crohn's Disease (VEDO-PREDIRESP)

Crohn Disease

France
Shaare Zedek Medical Center

Completed

Predicting Response to Vedolizumab in Pediatric Inflammatory Bowel Diseases

Crohn's Disease | Ulcerative Colitis | Inflammatory Bowel Disease

United States, Israel, Denmark, Ireland, Slovenia, United Kingdom
McMaster University

Completed

Mepolizumab in Chronic Obstructive Pulmonary Diseases (COPD) With Eosinophilic Bronchitis

Bronchitis | Chronic Obstructive Pulmonary Diseases | Chronic Airways Limitation

Canada
Takeda

Completed

Vedolizumab IV 300 mg in the Treatment of Fistulizing Crohn's Disease (ENTERPRISE)

Crohn's Disease

Spain, United Kingdom, Canada, United States, Netherlands, France, Italy
University of Thessaly

Recruiting

Impulse Oscillometry Measurements in Severe Eosinophilic Asthmatics Before and After Anti-IL-5 Factor Initiation (IMPOSE)

Severe Asthma

Greece
Massachusetts General Hospital
Dana-Farber Cancer Institute; Takeda

Not yet recruiting

Vedolizumab for the Treatment of Collagenous Gastritis

Collagenous Gastritis

United States
Takeda

Completed

An Open-label Study of Vedolizumab (MLN0002) in Participants With Ulcerative Colitis and Crohn's Disease (GEMINI LTS)

Crohn's Disease | Ulcerative Colitis

Belgium, United States, Korea, Republic of, Malaysia, Canada, Israel, Australia, Hungary, Czechia, Germany
Guy's and St Thomas' NHS Foundation Trust
Takeda

Unknown

Investigation of the Faecal Loss of Vedolizumab and Its Role in Influencing Serum Drug Levels, Outcomes and Response in Ulcerative Colitis (FAVOUR)

Ulcerative Colitis

United Kingdom

Search clinical trials for: Vedolizumab Placebo

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