Search clinical trials for: XR-NTX

Total 2348 results

Seattle Children's Hospital
Pfizer

Completed

Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot Study

ADHD | Autism

United States
AstraZeneca

Completed

Pediatric Bipolar Depression

Bipolar Depression

United States, Mexico, Taiwan, South Africa, Serbia, India, Colombia
AstraZeneca

Completed

Generalized Anxiety Disorder Adjunct Study

Anxiety Disorders | Anxiety | Anxiety Neuroses | Anxiety States

United States
AstraZeneca

Terminated

Study of the Broad Clinical Benefit for Seroquel XR With Flexible Dose as an add-on Therapy in the Treatment of Acute Bipolar Mania Patients With Partial Response to Current Therapy (RELEASE)

Acute Bipolar Mania

Korea, Republic of
Cingulate Therapeutics

Completed

CTx-1301 Comparative Bioavailability Study

ADHD

United States
AstraZeneca

Completed

Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (Seroquel XR) (QUENCH)

Schizophrenia

Korea, Republic of
Neuraptive Therapeutics Inc.

Active, not recruiting

Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries

Peripheral Nerve Injuries

United States
Pr Eric Goffin

Completed

Efficacy and Safety of a Double Icodextrin Dose in Elderly Incident CAPD Patients on Incremental PD. (DIDo)

Renal Insufficiency

Belgium
Takeda

Completed

Food Effect Study of Febuxostat XR in Healthy Participants

Gout

United States
Subhajit Chakravorty

Completed

The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence

Alcoholism | Sleep Initiation and Maintenance Disorders

United States
Romark Laboratories L.C.

Completed

Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis B

Chronic Hepatitis B

Singapore
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
AstraZeneca

Withdrawn

BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

Type 2 Diabetes

Brazil
Astellas Pharma Inc

Completed

Study to Evaluate the Effect and Safety of Quetiapine Extended Release (XR) (FK949E) in Major Depressive Disorder

Major Depressive Disorder

Japan
Janssen-Cilag International NV

Completed

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

Depressive Disorder, Major

Israel, Hungary, Korea, Republic of, Taiwan, Portugal, Turkey, Germany, Malaysia, Denmark, Bulgaria, Czechia, Belgium, Poland, Brazil, Netherlands, Argentina, Finland, Greece, South Africa, Austria, Kazakhstan, Norway, Sweden, United...
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)

Type 2 Diabetes Mellitus
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
AstraZeneca

Completed

Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

Diabetes Mellitus

United States
AstraZeneca
Quintiles, Inc.

Completed

Adult Bipolar Mania

Acute Mania

Bulgaria, Poland, Russian Federation, South Africa, Germany, Ukraine, Israel, India, Belgium
Boehringer Ingelheim

Completed

Bioavailability of 2 Different Nevirapine Extended Release Formulations Compared to Viramune® in HIV-1 Infected Subjects

HIV Infections
FUSMobile Inc.
Rambam

Completed

RAMBAM 021: Safety and Initial Feasibility of the Neurolyser XR for the Treatment of Chronic Low Back Pain

Facet Syndrome of Lumbar Spine

Israel
University of Guadalajara

Recruiting

Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity

Obesity

Mexico
AstraZeneca
Parexel

Completed

A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.

Type 2 Diabetes Mellitus

United States
Cook County Health
Bristol-Myers Squibb

Completed

Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia

Hyperglycemia | Diabetes Mellitus Type 2

United States
AstraZeneca

Completed

Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

Type 2 Diabetes

United States, Argentina, Mexico, Israel
Elcelyx Therapeutics, Inc.

Completed

Assessing the PK of Met DR, Met IR, and Met XR in Healthy Subjects

Healthy Subjects
Icahn School of Medicine at Mount Sinai
AstraZeneca

Completed

Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat

Generalized Anxiety Disorder | Major Depressive Disorder

United States
Chong Kun Dang Pharmaceutical

Completed

A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/500mg in Healthy Male Volunteers

Diabetes Mellitus, Type II

Korea, Republic of
VA Office of Research and Development
VA New York Harbor Healthcare System; VA Boston Healthcare System; Portland VA... and other collaborators

Recruiting

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

Epilepsy

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Indiana University
AstraZeneca

Completed

A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients

Panic Disorder

United States
University of Calgary
AstraZeneca

Completed

Serotonin Transporter Genetic Variation and Amygdala Responses to Antidepressant Medications in Major Depression

Major Depressive Disorder

Canada
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
GlaxoSmithKline

Terminated

Study Of Rosiglitazone XR In Subjects With Mild-to-Moderate Alzheimers

Alzheimer's Disease

United States, Bulgaria, Germany, Estonia, Korea, Republic of, China, Greece, Hungary, Russian Federation, Philippines, Austria, Chile, Mexico, Croatia, New Zealand, Peru, Puerto Rico, United Kingdom
GlaxoSmithKline

Completed

PK, Dose Proportionality, Food Effect And Repeat Dose Study Of Rosiglitazone XR In Healthy Volunteers (Rosi XR)

Alzheimer's Disease

Germany
Bristol-Myers Squibb

Completed

Body Weight Effects on Glucophage's Efficacy in Chinese Diagnosed T2DM Patients

Type 2 Diabetes Mellitus

China
Comprehensive Support Project for Oncology Research

Completed

National Surgical Adjuvant Study of Breast Cancer(N-SAS BC) 07 [RESPECT] (RESPECT)

Breast Cancer

Japan
Vanderbilt University Medical Center
Veloxis Pharmaceuticals

Recruiting

Cognitive Outcomes in Stable Renal Transplant Patients Switched fromTacrolimus to Envarsus XR™ (OPERATOR)

Renal Transplant

United States
AstraZeneca

Completed

Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

Type 2 Diabetes Mellitus

United Kingdom
University of Colorado, Denver

Withdrawn

Oxtellar Extended Release (Oxcarbazepine Extended Release) Patients With Trigeminal Neuralgia

Trigeminal Neuralgia
Oui Therapeutics, Inc.
National Institute of Mental Health (NIMH)

Enrolling by invitation

A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic

Suicidal Ideation | Suicide, Attempted

United States
Otsuka Pharmaceutical Development & Commercialization...

Recruiting

A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)

Attention Deficit/Hyperactivity Disorder

United States
FUSMobile Inc.

Active, not recruiting

Double Arm Pivotal Study to Evaluate the Neurolyser XR for the Treatment of Chronic Low Back Pain

Facet Syndrome of Lumbar Spine

United States
University of Oslo
Norwegian Institute of Public Health; Oslo University Hospital; The Research... and other collaborators

Completed

Naltrexone vs Buprenorphine-Naloxone for Opioid Dependence in Norway (NTX-SBX)

Opioid Dependence

Norway
Glaser Pediatric Research Network
Elizabeth Glaser Pediatric AIDS Foundation

Unknown

Glaser Obesity Study

Obesity

United States
Severance Hospital

Unknown

Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS) (ES-ARMS)

Schizophrenia | Abnormal Mental State

Korea, Republic of
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Scorpion Therapeutics, Inc.

Recruiting

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Non-Small Cell Lung Cancer | NSCLC | EGFR/HER2 Exon 20 Insertion Mutation

United States, Taiwan

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