Search clinical trials for: Xigris

Total 94 results

Boston Medical Center

Completed

Regression Discontinuity Design to Evaluate of Drotrecogin Alpha Effectiveness

Sepsis

United States
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Activated Protein C to Treat Acute Lung Injuries

Respiratory Distress Syndrome, Adult

United States
Eli Lilly and Company

Completed

Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis

Sepsis

United States, United Kingdom, France, Slovakia, Switzerland, Australia, Poland, Italy, Chile, Germany, Mexico
Eli Lilly and Company

Completed

An Open Label Study of Severe Sepsis in Adults

Severe Sepsis

Belgium
Skane University Hospital

Completed

Comparing Cytokines, Toxins Adsorbing oXiris Filter to ST150 Filter During CRRT in Patients With Septic Shock (oXiris)

Septic Shock | Acute Kidney Injury

Sweden
Centre Hospitalier Universitaire, Amiens
Baxter Healthcare Corporation

Recruiting

Effect of Oxiris® Membrane on Microcirculation Following Cardiac Surgery Under Cardiopulmonary Bypass: a Pilot Prospective Monocentric Study (Oxicard Study). (OXICARD)

Surgery | Cardiac Event

France
FRANCO TURANI
Baxter Healthcare Corporation

Unknown

The Membrane Adsorbing OXiris Filter in Septic Patients With AKI (MOSAKI)

Sepsis | Acute Renal Failure

Italy
Eli Lilly and Company

Completed

A Safety Evaluation of Drotrecogin Alfa (Activated) in Patients With Blood Cancer, Severe Infection Related to Bone Marrow Transplantation

Sepsis | Hematologic Neoplasms | Infection | Hematopoietic Stem Cell Transplantation

United States
Eli Lilly and Company

Completed

Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic Shock

Sepsis

Italy, United Kingdom, United States, Germany, Spain, Belgium, France, Australia, Czech Republic, Netherlands, Canada, Mexico, New Zealand, Finland, Portugal, Brazil, India, Switzerland
W.L.Gore & Associates

Completed

Evaluation of the GORE TIGRIS Vascular Stent (TIGRIS)

Peripheral Arterial Disease

United States
Seoul National University Hospital

Recruiting

Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane (HISTORIX)

Acute Kidney Injury Due to Sepsis

Korea, Republic of
National Taiwan University Hospital

Completed

Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock

Septic Shock | Sepsis, Severe

Taiwan
Eli Lilly and Company

Completed

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Severe Sepsis

United States, Belgium, Spain, France, Finland, Germany, Canada, United Kingdom, Puerto Rico
Samsung Medical Center

Completed

The Effects of oXiris in Cardiogenic Shock Requiring VA-ECMO (CLEAN ECMO)

Cardiogenic Shock

Korea, Republic of
Eli Lilly and Company

Completed

The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death

Sepsis

Canada, Finland, Belgium, Argentina, Chile, Australia, Austria, Brazil, Czech Republic, Denmark, Egypt, France
Preventive Oncology International, Inc.
Imalux

Completed

Study of the Diagnostic Efficacy of "Real Time" Niris 1300e Optical Coherence Tomography (OCT) Imaging System in the Management of Pre-invasive and Invasive Neoplasia of the Uterine Cervix (PUSHOCTII)

Cervical Intraepithelial Neoplasia | Cervix Cancer | CIN | Human Papillomavirus | Cervical Dysplasia

China
Edwards Lifesciences

Recruiting

Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve (MOMENTIS)

Mitral Valve Insufficiency | Mitral Stenosis

United States, Canada
Southeast University, China
Baxter Healthcare Corporation

Completed

A Multiple Centre, Cohort Study of New CRRT Membranes oXiris for Patients With Septic Shock

Acute Kidney Injury Due to Sepsis (Disorder)

China
Nefro Consultoria de Doenças Renais Ltda
Baxter Healthcare Corporation

Active, not recruiting

Continuous Renal Replacement Therapy With Oxiris in Acute Kidney Injury and Sepsis

Sepsis | Acute Kidney Injury

Brazil
St. Petersburg State Pavlov Medical University

Unknown

The Effects of Oxiris on Systemic Inflammation and Endothelial dysFunction (EOSIEF)

Acute Kidney Injury Due to Circulatory Failure (Disorder)

Russian Federation
Clinica CES
Baxter Healthcare Corporation

Completed

RRT With a Cytokine Absorption Filter (oXiris ®) in Patients With Septic Shock

Septic Shock | Acute Kidney Injury

Colombia
Centre Hospitalier Universitaire Dijon

Completed

Evaluation of Oxiris Membrane as a Treatment for Ischemia-reperfusion Syndrome in Cardiogenic Shock Treated With Extracorporeal Life Support (ECMO/ECLS): A Randomized Pilot Study ECMORIX (ECMORIX)

Cardiogenic Shock

France
University of Oklahoma

Terminated

Optical Coherence Tomography: An Adjunct to Flexible Bronchoscopy in the Diagnosis of Lung Cancer (OCT)

Lung Cancer

United States
Allergan

Completed

A Safety and Efficacy Study of LiRIS® in Females With Interstitial Cystitis With Hunner's Lesions

Ulcer | Cystitis, Interstitial

United States, Canada
Turku University Hospital
University of Turku

Recruiting

Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock (HEMOX-HDF)

Septic Shock | Acute Kidney Injury

Finland
Allergan
TARIS Biomedical, Inc.

Terminated

Safety, Tolerability and Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis

Interstitial Cystitis

United States, Canada
University of Zurich

Completed

Visualization of the Intubation Pathway With the "IRRIS"-Device (IRRIS)

Difficult Intubation

Switzerland
Allergan

Completed

A Safety and Efficacy Study of LiRIS® in Females With Interstitial Cystitis/Bladder Pain Syndrome

Cystitis, Interstitial | Painful Bladder Syndrome

United States, Canada
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation; Germans Trias i Pujol Hospital; Fundació Institut...

Completed

Increased Adsorption Membranes During Cardiopulmonary Bypass

Systemic Inflammatory Response Syndrome | Acute Kidney Injury | Cardiopulmonary Bypass | Cardiac Surgery Associated - Acute Kidney Injury

Spain
Hospital Universitari de Bellvitge
Gambro Renal Products, Inc.

Completed

Clinical Trial to Evaluate the Use of an Adsorption Membrane (oXiris®) During Cardiopulmonary Bypass Surgery

Cardiopulmonary Bypass | Cardiac Surgical Procedures

Spain
Intelligent Medical Implants GmbH

Unknown

IRIS PILOT - Extended Pilot Study With a Retinal Implant System

Retinitis Pigmentosa | Choroideremia | Cone-Rod Dystrophy
University of Missouri-Columbia

Completed

Use of Traditional Curved Iris Scissors or the Wuennenberg Modified Curved Iris Scissors for Skin Surgery (TISMIS)

Skin Cancer

United States
Careggi Hospital
University of Florence

Active, not recruiting

Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients

Sepsis | Systemic Inflammatory Response Syndrome | Critical Illness | Acute Kidney Injury

Italy
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN-69 Oxiris) vs (Standard AN-69) in COVID-19 (oXAKI-COV)

Covid19 | AKI

Mexico
George Washington University
Eli Lilly and Company

Completed

Safety and Dose Finding Study of Xigris in Hemodialysis Patients (Xigris1003)

End Stage Renal Disease

United States
University of Rochester
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Activated Protein C in Acute Stroke Trial (APCAST)

Stroke

United States
Eli Lilly and Company

Completed

Adjuvant Treatment of Pulmonary Embolism With Drotrecogin Alfa (Activated): Phase II Exploratory Study

Submassive Pulmonary Embolism

Germany
SunWay Biotech Co., LTD.

Completed

Effects of Vigiis 101-LAB on a Healthy Populations' Gut Microflora

Gastrointestinal Microbiome

Taiwan
Allergan
TARIS Biomedical, Inc.

Completed

Safety Study of LiRIS in Interstitial Cystitis (IC) Patients

Interstitial Cystitis

Canada
SunWay Biotech Co., LTD.
National Taiwan University Hospital; Chung Shan Medical University

Completed

Effects of Vigiis 101-LAB on a Healthy Populations' Gut Microflora, Peristalsis, Immunity, and Anti-oxidative Capacity (Vigiis101)

Gastrointestinal Microbiome

Taiwan
Universitaire Ziekenhuizen KU Leuven

Terminated

IRIS Alfa Clinical Trial A Monocentric, Academic Clinical Trial Safety Study of a Prototype of a New Vitrectomy Device. (IRIS)

Vitrectomy

Belgium
Yunling Zhang
Shandong University of Traditional Chinese Medicine; Huairou Hospital of Traditional...

Completed

Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations

Ischemic Stroke

China
Yunling Zhang
Shandong University of Traditional Chinese Medicine; Huairou Hospital of Traditional...

Unknown

Heat-clearing and Blood-activating Chinese Medicinal Components in Acute Cerebral Infarction

Ischemic Stroke

China
KK Women's and Children's Hospital

Not yet recruiting

Targeted Fortification of Pasteurized Donor Human Milk

Growth Failure | Very Low Birth Weight Infant | Donor Breast Milk

Singapore
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

IRIS Hook Assisted Phacoemulsification in Vitrectomized Eyes

Cataract | Vitrectomy

China
Intuitive Surgical

Completed

A Prospective Post-Market Study to Evaluate the Clinical Utility of IRIS, a Three-dimensional (3-D) Anatomical Modeling Software for Pre-operative Surgical Planning and Intra-operative Navigation for Nephrectomy

Kidney Cancer

United States
PainQx, Inc
National Institute on Drug Abuse (NIDA)

Completed

Development of a Medical Device Utilizing an EEG-Based Algorithm for the Objective Quantification of Pain

Chronic Pain

United States
Allergan
TARIS Biomedical, Inc.

Terminated

Double-Blind Placebo Controlled Study of Safety,Tolerability, and Efficacy of LiRIS® in Women With Interstitial Cystitis

Interstitial Cystitis

United States, Canada
University of Zurich

Completed

The Effects of a Polyethyleneimine-coated Membrane (oXiris™) for Hemofiltration Versus Polymyxin B- Immobilized Fibre Column (Toraymyxin™) for Hemoperfusion on Endotoxin Activity and Inflammatory Conditions in Septic Shock- A Randomized Controlled Pilot Study (ENDoX-study)

Patients in Septic Shock

Switzerland
National University Hospital, Singapore

Completed

Efficacy and Safety of Heparin-grafted Membrane for CRRT (CARROM)

Hemorrhage | Acute Kidney Injury | Coagulopathy

Singapore

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