Search clinical trials for: Xyrem (sodium oxybate) oral solution

Total 2473 results

Jazz Pharmaceuticals

Completed

Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy

Narcolepsy

Canada
Brigham and Women's Hospital

Withdrawn

Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia

Traumatic Brain Injury | Narcolepsy | Hypersomnia

United States
Jazz Pharmaceuticals

Completed

Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia

Fibromyalgia

United States
UCB Pharma SA

Completed

Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes

Narcolepsy With Cataplexy

Belgium
Tufts Medical Center

Withdrawn

The Effect of Sodium Oxybate on Sleep Architecture

Mechanically Ventilated ICU Patients

United States
Jazz Pharmaceuticals

Completed

Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia

Fibromyalgia

United States
Baylor College of Medicine
Jazz Pharmaceuticals

Completed

Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD) (Xyrem)

Parkinson Disease
St. Luke's Hospital, Chesterfield, Missouri
Jazz Pharmaceuticals

Completed

Enhancing Slow Wave Sleep With Sodium Oxybate

Sleep

United States
Kristina Simonyan
National Institutes of Health (NIH); National Institute on Deafness and Other...

Completed

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

Spasmodic Dysphonia | Voice Tremor

United States
University Hospital, Montpellier

Completed

Sodium Oxybate in Idiopathic Hypersomnia (SODHI)

Idiopathic Hypersomnia

France
Jazz Pharmaceuticals

Completed

Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy

Narcolepsy

United States, France, Germany, Switzerland
Washington University School of Medicine
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction

Amyloid-beta

United States
Nathan Kline Institute for Psychiatric Research
Jazz Pharmaceuticals

Completed

Sodium Oxybate in Schizophrenia With Insomnia

Schizophrenia | Insomnia Related to Schizophrenia (307.42)

United States
Christian Baumann

Completed

Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson's Disease (PD-Xyrem)

Sleep-wake Disturbances in Motor-phase Parkinson's Disease

Switzerland
Ramin Khatami

Unknown

Sodium Oxybate in Patients With Episodic and Chronic Cluster Headache (SOinCH)

Cluster Headache
Concert Pharmaceuticals

Completed

A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

Narcolepsy, Excessive Daytime Sleepiness

United Kingdom
University of Medicine and Dentistry of New Jersey
Jazz Pharmaceuticals

Terminated

Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome

Chronic Fatigue Syndrome

United States
Imperial College London
Medical Research Council

Completed

SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE) (SAFFE)

Chronic Fatigue Syndrome

United Kingdom
Orphan Medical

Completed

Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients

Narcolepsy

United States, Canada, Switzerland
Centre for Addiction and Mental Health

Completed

Xyrem and Brain Dopamine in Narcolepsy

Healthy Controls | Narcolepsy With Cataplexy

Canada
Mayo Clinic

Recruiting

Low Sodium Oxybate in Patients With Idiopathic Hypersomnia

Idiopathic Hypersomnia

United States
Orphan Medical
Johns Hopkins University

Completed

Physiological, Behavioral and Subjective Effects of Drugs (GHB)

Sedative Abuse

United States
G. d'Annunzio University

Completed

PrevenTion of Contrast-inducEd nephroAThy With urinE Alkalinization (TEATE)

Acute Kidney Injury | Contrast Media Reaction

Italy
University Hospital, Ghent
UCB Pharma

Withdrawn

Sodium Oxybate in Patients With Chronic Fatigue Syndrome.

Chronic Fatigue Syndrome

Belgium
IBSA Institut Biochimique SA
Cromsource

Active, not recruiting

Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)

Congenital Hypothyroidism

United States
Federal University of Mato Grosso

Completed

Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunteers

Edema | Perioperative/Postoperative Complications

Brazil
National Center for Complementary and Integrative...

Completed

Effects of Black Cohosh on Menopausal Hot Flashes

Hot Flashes | Osteoporosis, Postmenopausal | Postmenopause

United States
Procter and Gamble

Completed

Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis

Dentin Sensitivity

United States
Clinica Universidad de Navarra, Universidad de...

Completed

Prevention of Contrast Induced Nephropathy (NIC) by Intravenous Versus Oral Rehydration (NIC)

KIDNEY FAILURE, ACUTE

Spain
Stanford University

Completed

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.

Sleep Initiation and Maintenance Disorders

United States
National Cancer Center, Korea
Seoul National University Hospital; Seoul National University Bundang Hospital and other collaborators

Unknown

Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery

Colorectal Cancer

Korea, Republic of
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing

Colon Cleansing

United States
Ligand Pharmaceuticals

Completed

Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus (L6972-02)

Type 2 Diabetes Mellitus

United States
The Western Pennsylvania Hospital
West Penn Allegheny Health System

Withdrawn

Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy (HYDRATE)

Contrast Induced Nephropathy

United States
Baxter Healthcare Corporation
Halozyme Therapeutics

Withdrawn

Efficacy and Time and Resources for Hylenex-facilitated SC Rehydration Versus ORT for Dehydrated Children in the Emergency Department (ED) (INFUSE-TM)

Dehydration
AlzProtect SAS

Active, not recruiting

A Study to Assess Tolerability, Safety, Pharmacokinetics and Effect of AZP2006 in Patients With PSP

Progressive Supranuclear Palsy

France
Crinetics Pharmaceuticals Inc.

Completed

Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

Healthy Volunteers

United States
US Department of Veterans Affairs

Completed

Safety and Efficacy of Routine Colonoscopy Preparations

Spinal Cord Injury

United States
Crinetics Pharmaceuticals Inc.

Completed

A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers

Healthy Volunteers

Australia
UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
National Institute of Allergy and Infectious Diseases...

Recruiting

A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection

Multi-Drug Resistant Hiv-1 Infection | HIV-1 Infection

United States
Jazz Pharmaceuticals

Completed

A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.

Fibromyalgia

Spain, United States, Netherlands, United Kingdom, France, Germany, Italy, Poland
Jazz Pharmaceuticals

Completed

A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia

Fibromyalgia

United States
Guzide UGUCU

Completed

Effects of the Different Concentrations of Oral Dextrose Solution Applying With Supportive Positions on Pain During Heel-Stick Sampling in Premature Infants

Pain

Turkey
Galapagos NV

Completed

A Study to Evaluate the Effects of Single and Multiple Oral Doses of GLPG3970

Healthy | Psoriasis

Belgium, Moldova, Republic of, Ukraine
IRCCS Burlo Garofolo

Completed

Newborn Cortical Response to Pain and Non Pharmacological Analgesia

Analgesia
Fernando Bacal

Recruiting

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation (HSS-HT)

Heart Transplantation | Acute Kidney Injury

Brazil
Aires Pharmaceuticals, Inc.

Terminated

A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Australia, Hungary
Boehringer Ingelheim

Completed

Pharmacokinetics and Safety Study of Tipranavir in Combination With Low Dose Ritonavir in Human Immunodeficiency Virus (HIV)-Infected Children

HIV Infections

United States, Argentina, Brazil, Canada, France, Germany, Italy, Mexico, Puerto Rico, Spain
Foresee Pharmaceuticals Co., Ltd.

Completed

Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045

Healthy Volunteers

Australia

Search clinical trials for: Xyrem (sodium oxybate) oral solution

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lebanon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations