Search clinical trials for: alteplase or tenecteplase

Total 5671 results

Centre Hospitalier Sud Francilien

Completed

Tirofiban Plus Intravenous Thrombolysis in Acute Anterior Choroidal Infarction or Paramedian Pontine Infarction (TITACIPPI)

Acute Anterior Choroidal Infarction (ACI) | Paramedian Pontine Infarction (IPP)

France
Chinese University of Hong Kong
Queen Mary Hospital, Hong Kong; Princess Margaret Hospital, Canada; Tuen Mun... and other collaborators

Not yet recruiting

Intravenous Thrombolytic Therapy in Acute Ischemic Stroke Patients on DOAC (DOAC-IVT)

CVA (Cerebrovascular Accident)

Hong Kong
The First Affiliated Hospital of University of...

Recruiting

Endovascular Thrombectomy Alone Versus Intravenous Thrombolysis Plus Thrombectomy on Acute Basilar Artery Occlusion

Basilar Artery Occlusion | Acute Cerebrovascular Accident | Stroke Due to Basilar Artery Occlusion

China
Centre Hospitalier Sud Francilien

Completed

Dual IntraVenous Thrombolysis Approach (DIVA) in Patients With Medium-vessel-occlusion Strokes: a Retrospective Study (DIVArétro)

Acute Ischemic Stroke Due to Medium-vessel-occlusion

France
Boehringer Ingelheim

Completed

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (ORIGINAL)

Stroke

China
Centre Hospitalier Sud Francilien

Recruiting

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes (DISTAL-IVT)

Acute Distal Vessel Occlusion Stroke

France
NHS Greater Glasgow and Clyde
University of Edinburgh; Oxford University Hospitals NHS Trust; University of...

Unknown

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST2)

Ischemic Stroke

United Kingdom
University of Calgary

Completed

Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke (AcT)

Stroke, Acute | Thromboses, Intracranial

Canada
Haukeland University Hospital

Terminated

The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Cerebrovascular Disorders | Ischemic Stroke | Stroke, Acute

Norway
Lars Thomassen
The Research Council of Norway

Completed

Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke (NOR-TEST)

Ischemic Stroke

Norway
Boehringer Ingelheim

Completed

A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)

Ischemic Stroke

Australia, New Zealand
Reza Behrouz, DO

Withdrawn

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) (TALISMAN)

Ischemic Stroke

United States
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai Fifth People's Hospital; Shanghai Deji... and other collaborators

Recruiting

Tenecteplase Thrombolytic Therapy for Acute Ischemic Stroke in China (TTT-AIS CHINA)

Ischemic Stroke

China
University of Melbourne
Professor Mark Parsons

Recruiting

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients With Large Vessel Occlusion (ETERNAL-LVO)

Ischemic Stroke

Australia
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-Ⅲ）

Acute Ischemic Stroke

China
Beijing Tiantan Hospital
Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd; The Place Pharmaceutical(Jiangsu)...

Active, not recruiting

Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients （3T Stroke-II）

Acute Ischemic Stroke

China
Chiesi Farmaceutici S.p.A.

Terminated

Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) Functionality (READY 1)

Thrombosis | Catheter Occlusion

United States, Argentina, Belgium, Czechia, Poland, Romania, Spain
University of Melbourne

Recruiting

Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (POST-ETERNAL)

Basilar Artery Occlusion

Australia
Niguarda Hospital

Completed

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS EXP)

Stroke | Cerebrovascular Accident

Italy
Tomsk National Research Medical Center of the Russian...

Completed

Intramyocardial Haemorrhage in Patients With Primary STEMI (HaemInCor)

Myocardial Infarction | Myocardial Injury | STEMI | Myocardial Necrosis

Russian Federation
Melbourne Health

Completed

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa)

Stroke, Acute, Stroke Ischemic

Australia
Kaiser Permanente
Genentech, Inc.

Terminated

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Pleural Effusion

United States
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; The Second Affiliated... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase (CHABLIS-T)

Stroke

China
NHS Greater Glasgow and Clyde
University of Glasgow

Completed

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) (ATTEST)

Stroke

United Kingdom
Beijing Tiantan Hospital

Recruiting

Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5 (TRACE-5)

Ischemic Stroke, Acute

China
Boehringer Ingelheim

Terminated

Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest - The TROICA Trial

Heart Arrest

Germany, Belgium, Sweden, France, Austria, Italy, Norway, Spain, Switzerland
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters (TROPICS 2)

Dysfunctional Central Venous Access Catheters
University Of Perugia

Terminated

Tenecteplase Pulmonary Embolism Italian Study

Pulmonary Embolism

Italy
The George Institute
University of Calgary; Berry Consultants

Not yet recruiting

ACT-GLOBAL Adaptive Platform Trial for Stroke (ACT-GLOBAL)

Stroke
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters (TROPICS 1)

Dysfunctional Central Venous Access Catheters
Genentech, Inc.

Completed

A Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis Catheters (TROPICS 3)

Dysfunctional Hemodialysis Catheters
General Hospital of Shenyang Military Region

Completed

Boosting REcanalization of Thrombectomy for Ischemic Stroke by Intra-arterial TNK (BRETIS-TNK)

Ischemic Stroke

China
ProMedica Health System
Genentech, Inc.

Completed

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial (ALLY)

Ischemic Stroke

United States
Second Affiliated Hospital of Guangxi Medical University
CSPC Pharmaceutical Group Limited

Not yet recruiting

Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke (ATTIS)

Acute Ischemic Stroke
Hospital Moinhos de Vento
Boehringer Ingelheim; Ministry of Health, Brazil; Brainomix Limited; iSchemaView...

Recruiting

Randomization to Extend Stroke Intravenous ThromboLysis In Evolving Non-Large Vessel Occlusion With TNK (RESILIENT (EXTEND-IV)

Ischemic Stroke, Acute

Brazil
First Hospital of China Medical University

Not yet recruiting

Additive Effects of Intra-arterial Tenecteplase for Successful Thrombectomy Due to Acute Basilar Artery Occlusion

Basilar Artery Occlusion | Thrombectomy | Tenecteplase
Hui-Sheng Chen

Recruiting

Improving Neuroprotective Strategy for Ischemic Stroke With Poor Recanalization After Thrombectomy by Intra-arterial TNK (INSIST-TNK)

Ischemic Stroke

China
University of Manitoba
Hoffmann-La Roche

Terminated

Alteplase for Blood Flow Restoration in Hemodialysis Catheters

Thrombosis

Canada
University Hospital Center of Martinique

Withdrawn

Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion (DIVA)

Nervous System Disorders | Cerebral Artery
University of Alberta

Completed

Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic Stroke (TIAS)

Stroke | Brain Ischemia | Cerebral Infarction

Canada
Assistance Publique - Hôpitaux de Paris
Boehringer Ingelheim; German Federal Ministry of Education and Research

Completed

PEITHO Pulmonary Embolism Thrombolysis Study (PEITHO)

Pulmonary Embolism

Israel, Poland, Portugal, Spain, Austria, Belgium, France, Germany, Greece, Hungary, Italy, Slovenia
Wake Forest University Health Sciences

Terminated

Clot Dissolving Treatment for Blood Clots in the Lungs

Pulmonary Embolism

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Hospital of Southern Medical University

Recruiting

Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy (PEARL)

Stroke, Acute Ischemic

China
University of Melbourne

Not yet recruiting

Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke

Cerebrovascular Disorders | Central Nervous System Diseases | Ischemic Stroke, Acute | Brain Disorder

Australia
Boehringer Ingelheim

Completed

A Trial on Efficacy and Safety of Full Dose Tenecteplase Combined With Unfractionated Heparin (UFH) or Enoxaparin in Acute Myocardial Infarction (AMI) in the Prehospital Setting (ASSENT 3 Plus)

Myocardial Infarction
Boehringer Ingelheim

Completed

A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 (TRISTARDS)

Acute Respiratory Distress Syndrome

Spain, Germany, Italy, Belgium, Mexico, Netherlands, India, France, Malaysia, Austria, Brazil, Russian Federation, Turkey
University of North Carolina, Chapel Hill
Genentech, Inc.

Completed

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

Ischemic Stroke

United States
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
University of Virginia
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B)

Stroke

United States

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