Search clinical trials for: cyclosporine A (CyA)

Total 14386 results

Eli Lilly and Company

Completed

A Study of Baricitinib and Ciclosporin in Healthy Participants

Healthy Volunteers

United Kingdom
Institute of Hematology & Blood Diseases Hospital

Recruiting

Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function

Aplastic Anemia

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Germany, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Stage IV Kidney Cancer

Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Transplantation for Metastatic Solid Tumors

Neoplasm Metastasis

United States
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom

Completed

Ciclosporin to Reduce Reperfusion Injury in Primary PCI (CAPRI)

Myocardial Reperfusion Injury

United Kingdom
Aurinia Pharmaceuticals Inc.

Completed

Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients (ESSENCE)

Psoriasis

Canada, Germany, Poland
M.D. Anderson Cancer Center

Completed

Treatment of Myelodysplastic Syndrome (MDS) With Cytokine-Immunotherapy for Low-Risk MDS

Myelodysplastic Syndrome

United States
Assistance Publique - Hôpitaux de Paris
Agence de La Biomédecine

Completed

Cyclosporine Dose Adjustment According to Calcineurin Activity After Allogeneic Hematopoietic Stem-cell Transplantation (CALCICLO)

Hematopoietic Stem Cell Transplantation | Graft Versus Host Disease

France
Sigmoid Pharma

Completed

PK, Safety & Tolerability of CyCol® Versus Sandimmune® in Healthy Subjects (CYC102)

Healthy
University of Waterloo
Sun Pharmaceutical Industries Limited

Recruiting

Improving Drop Instillation Comfort of a Cyclosporine A Solution

Dry Eye Disease

Canada
Amgen

Withdrawn

Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy

Severe Aplastic Anemia (SAA)
Tehran University of Medical Sciences

Completed

Cyclosporine-A Versus Prednisolone for Induction of Remission in Auto-immune Hepatitis

Autoimmune Hepatitis

Iran, Islamic Republic of
Hospices Civils de Lyon

Completed

Does Cyclosporine ImpRove Clinical oUtcome in ST Elevation Myocardial Infarction Patients at 3 Years of Follow-up. CIRCUS II Study (CIRCUS II)

ST Elevation Acute Myocardial Infarction

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye Syndrome

Moderate to Severe Dry Eye Syndrome

France
Peking Union Medical College Hospital
Beijing Tongren Hospital; Shanghai Fosun Pharmaceutical Industrial Development... and other collaborators

Recruiting

Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN

Idiopathic Membranous Nephropathy

China
Novartis Pharmaceuticals

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program (Senator)

Renal Transplantation

Germany
Janssen Research & Development, LLC

Completed

A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir

Healthy

Belgium
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Cyclosporine in Treating Patients With Recurrent or Refractory Angioimmunoblastic T-Cell Lymphoma

Lymphoma

United States
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
Novartis

Completed

Conversion From Tacrolimus to Cyclosporine Microemulsion in Liver Transplant Patients With New Onset Diabetes After the 3rd Month Post-transplant

Maintenance Liver Transplant Patients With New Onset Diabetes
Masonic Cancer Center, University of Minnesota

Recruiting

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Follicular Lymphoma | Multiple Myeloma | Myelofibrosis | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | Mantle-Cell Lymphoma | Diffuse Large B Cell Lymphoma | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Myelodysplasia | Acute Myeloid Leukemia... and other conditions

United States
Hospital Hietzing

Completed

Effect of Ciclosporin Eyedrops on Sjögren Syndrome

Dry Eye Syndromes

Austria
Wei Gao

Not yet recruiting

Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation

Liver Transplant; Complications | Immunosuppression | Immune Tolerance

China
Shandong Qilu Stem Cells Engineering Co., Ltd.
Second Affiliated Hospital of Zhengzhou University; The Second Affiliated Hospital... and other collaborators

Recruiting

Clinical Study of UCB Combined With UC-MSCs in the Treatment of Bone Marrow Failure Disorders

Bone Marrow Failure Disorders

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Conversion to Sirolimus vs. Continued Use of Calcineurin Inhibitors in Kidney Transplant Recipients

Renal Transplantation
Bing Han

Not yet recruiting

Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia

Aplastic Anemia

China
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

United States, Croatia, France, Germany, Greece, Hungary, India, Israel, Italy, Portugal, Spain
University of Oslo School of Pharmacy

Completed

Interaction Between Rimonabant and Cyclosporine and Tacrolimus (RIMONA-PILOT)

Renal Transplantation

Norway
Institute of Rheumatology, Prague
Charles University, Czech Republic; Palacky University; Ministry of Health, Czech... and other collaborators

Completed

Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study (CYCLOFA-LUNE)

Systemic Lupus Erythematosus | Lupus Nephritis

Czech Republic
Technische Universität Dresden

Completed

Prednisolone vs. Ciclosporine in Severe Atopic Eczema (PROVE)

Atopic Dermatitis

Germany, Austria
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Recruiting

Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes (DF-IL2-REP)

Type 1 Diabetes

France
Johns Hopkins University

Completed

Long-term Topical Cyclosporine for Atopic Keratoconjunctivitis

Atopic Keratoconjunctivitis

United States
Assiut University

Unknown

Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis

Membranoproliferative Glomerulonephritis
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft Recipients

Kidney Transplantation | Graft Rejection | Kidney Failure
University Hospital, Limoges

Completed

Reduction in the Risk of Rejection by Mycophenolate Mofetil Dose Adjustment in Liver Transplant Patients With Side Effects Caused by the Calcineurine Inhibitors (MONOCEPT)

Liver Transplantation

France
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Comparison of Extended Release Tacrolimus (Advagraf) and Cyclosporine A Microemulsion on Renal Function in Healthy Volunteers

Healthy

Canada
Semmelweis University

Unknown

Autoimmunity in Retinitis Pigmentosa

Retinitis Pigmentosa

Hungary
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Intra-Osseous Co-Transplant of UCB and hMSC

Myelodysplastic Syndromes | Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Lymphoid Malignancies | Relapsed Non-Hodgkin Lymphoma and other conditions

United States
Hospices Civils de Lyon

Unknown

LOW CYCLO: Study Evaluating the Benefit of Two Doses of Ciclosporine in de Novo Cardiac Transplant

Cardiac Transplantion

France
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Alexandria University

Completed

Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study

Dry Eye
Novartis Pharmaceuticals

Terminated

Liver Fibrosis in Patients Transplanted for Hepatitis C Receiving Either Cyclosporine Microemulsion or Tacrolimus

Hepatitis C | Liver Transplant

United States, Switzerland
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Trial of Hetrombopag in Healthy Subjects

Sever Aplastic Anaemia

China
Santen SAS

Completed

Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe Keratitis (FAST)

Keratitis

France
Bristol-Myers Squibb

Completed

A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids

Renal Transplant

Argentina, Australia, India, United States, Belgium, Brazil, Poland, Mexico, Canada, France, Germany, Spain
Santen SAS

Completed

Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)

Conjunctivitis, Vernal

France
National Institute of Allergy and Infectious Diseases...

Terminated

A Study To Test An Anti-Rejection Therapy After Kidney Transplantation

Kidney Transplantation

United States

Search clinical trials for: cyclosporine A (CyA)

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