Search clinical trials for: methotrexate (MTX)

Total 3614 results

Janssen Biotech, Inc.
Merck Sharp & Dohme LLC

Completed

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Autoimmune Diseases | Arthritis | Arthritis, Rheumatoid

United States, United Kingdom, Belgium, Greece, Canada, Germany, Sweden, Austria
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Hematologic and Lymphocytic Disorder | Allogeneic Stem Cell Transplant Recipient

United States
Japan Biological Agent Study Integrated Consortium

Completed

Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in Japan (JESMR)

Rheumatoid Arthritis

Japan
University Hospital Freiburg
University Hospital Tuebingen

Unknown

Freiburg ZNS-NHL Study

Primary Non Hodgkin Lymphoma of the Central Nervous System

Germany
Pfizer

Completed

Characterize Patients With Moderately Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

Childhood Acute Lymphoblastic Leukemia in Remission

United States, Canada, Australia
Pierre Fabre Medicament

Completed

Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer

Recurrent or Metastatic Head and Neck Carcinoma

France
Seoul National University Hospital

Recruiting

MTX Hold During Covid-19 Booster

Rheumatoid Arthritis

Korea, Republic of
Maxinovel Pty., Ltd.

Recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Max-40279-01 in Patients With Advanced Gastric Cancer or Gastroesophageal Junction Cancer

Gastric Cancer | Gastroesophageal Junction Cancer

China
Benjamin Izar

Terminated

ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma (ATX-101)

Leiomyosarcoma | Liposarcoma

United States
CymaBay Therapeutics, Inc.

Completed

Safety and Tolerability Study of MBX-2044 in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Nicolaus Copernicus University

Completed

The Evaluation of Vitiligous Lesions Repigmentation After Topical Administration of Methotrexate in Patients With Active Vitiligo (EVRAM)

Non-segmental Vitiligo

Poland
Amneal Pharmaceuticals, LLC
Accutest Research Laboratories (I) Pvt. Ltd.

Unknown

BE Study in Patients - Methotrexate Tablets

Rheumatoid Arthritis | Psoriasis

India
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's Lymphoma

Lymphoma

United States
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United States, Germany, Hungary, Bulgaria, Mexico, Peru, Chile, Romania, Spain
Philogen S.p.A.

Terminated

A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX

Rheumatoid Arthritis

Switzerland, Germany, Italy
Hee Young Ju

Not yet recruiting

Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children

Lymphoblastic Leukemia in Children
Fox Chase Cancer Center

Completed

Dose Dense MVAC for Muscle Invasive Bladder Cancer

Muscle Invasive Bladder Cancer | High Risk Urothelial Carcinoma of the Upper Urinary Tracts

United States
University of North Carolina, Chapel Hill
Philips Oral Healthcare

Completed

Dental Plaque Removal Study (PAU2)

Gingivitis | Gum Disease

United States
Stealth BioTherapeutics Inc.
ICON Clinical Research

Completed

Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events (EMBRACE)

Reperfusion Injury | STEMI

United States, Hungary, Germany, Poland
Boston Children's Hospital

Suspended

Methotrexate Polyglutamate Measurements in Patients With Inflammatory Bowel Disease

IBD

United States
Seoul National University Hospital

Completed

One or Two Week Methotrexate Discontinuation on Efficacy of Influenza Vaccination in Rheumatoid Arthritis.

Autoimmune Diseases | Rheumatoid Arthritis | Vaccine Reaction | Influenza

Korea, Republic of
Peking Union Medical College Hospital

Recruiting

The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage

Uveitis, Anterior | Adalimumab

China
Keio University
Eisai Co., Ltd.

Active, not recruiting

Evaluation of the Optimal MTX Dose as an Add-on Therapy to Adalimumab for RA Patients in Japan, South Korea and Taiwan

Rheumatoid Arthritis

Korea, Republic of, Taiwan, Japan
XBiotech, Inc.

Not yet recruiting

Natrunix Versus Methotrexate in Rheumatoid Arthritis

Rheumatoid Arthritis
Huashan Hospital

Active, not recruiting

A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSL (ORMD2021)

Primary Central Nervous System Lymphoma

China
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Peking Union Medical College Hospital

Unknown

Efficacy and Safety of Fecal Microbiota Transplantation in Patients With Rheumatoid Arthritis Refractory to Methotrexate (FARM)

Rheumatoid Arthritis

China
Aswan University Hospital

Active, not recruiting

Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum Chitotriosidase Level in Psoriasis

Psoriasis

Egypt
Aswan University Hospital

Unknown

Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum TWEAK Level in Psoriasis

Psoriasis

Egypt
University of Oxford

Completed

A Clinical Trial in Patients With Breast Cancer Susceptibility Gene (BRCA) Defective Tumours (6MP)

Breast Cancer | Ovarian Cancer

United Kingdom
Chinese University of Hong Kong

Completed

The Chinese University of Hong Kong Early Arthritis Study (ERA)

Rheumatoid Arthritis

China
Qilu Hospital of Shandong University

Completed

The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment

Arthritis, Rheumatoid

China
University of Washington
National Cancer Institute (NCI)

Completed

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Stage IV Breast Cancer | Leptomeningeal Metastases | Recurrent Breast Cancer | Central Nervous System Metastases | Tumors Metastatic to Brain

United States
H. Lee Moffitt Cancer Center and Research Institute

Completed

Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation

Acute Graft Versus Host Disease

United States
H. Lee Moffitt Cancer Center and Research Institute

Completed

Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX

Mucositis | Graft-versus-host Disease

United States
Cook Group Incorporated

Completed

Zilver PTX Drug-Eluting Peripheral Stent Study

Peripheral Arterial Disease

Germany, Switzerland
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia

United States
Cook Group Incorporated

Completed

Formula PTX Renal Stent Clinical Study

Renal Artery Stenosis

United Kingdom, Germany, Czechia, France
Foundation for Innovative New Diagnostics, Switzerland
Universidad Peruana Cayetano Heredia; Burnet Institute; National Institute for... and other collaborators

Completed

Clinical Evaluation of the Truenat Point-of-care Tuberculosis Diagnostic Test

Tuberculosis, Pulmonary

Ethiopia, India
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

United States
Tulane University Health Sciences Center

Completed

Trichomonas Vaginalis Repeat Infections Among HIV Negative Women

Vaginitis Trichomonal or Due to Trichomonas

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

United States, Germany
Chinese University of Hong Kong

Unknown

Fosamax for Childhood Cancer Survivors

Osteoporosis

Hong Kong
Tong Chen
Antengene Corporation

Recruiting

Selinexor in Combination With MTX+Ritu to Treat R/R CNSL

Central Nervous System Lymphoma

China
SinoMab BioScience Ltd

Recruiting

A Study Assessing the Efficacy and Safety of SM03 in Patients With Active Rheumatoid Arthritis Receiving MTX

Rheumatoid Arthritis(RA)

China
MBX Biosciences

Completed

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects

Healthy

United States
Merck Sharp & Dohme LLC

Terminated

Safety and Efficacy of MK-8457 and Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Despite MTX Therapy (P08683, MK-8457-008)

Rheumatoid Arthritis (RA)
UCB Pharma SA

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
Bristol-Myers Squibb

Completed

A Phase III Study of Abatacept (BMS-188667) in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate

Rheumatoid Arthritis

United States

Search clinical trials for: methotrexate (MTX)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Lebanon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations