Search clinical trials for: metoprolol succinate and nebivolol

Total 697 results

East Coast Institute for Research

Completed

Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function

Hypertension | Female Sexual Dysfunction

United States
Saniona

Completed

A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate

Phase 1

Germany
Thomas Jefferson University
Forest Laboratories

Completed

Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure (ENCOMPASS)

Hypertension | Peripheral Artery Disease

United States
Trinity Hypertension & Metabolic Research Institute

Completed

Efficacy and Safety of Nebivolol Versus Metoprolol in Hypertensive Subject Taking Amlodipine

JNC 7 Stage 1 or 2 Hypertension

United States
University of Minnesota
University of Alabama at Birmingham; United States Department of Defense

Terminated

Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States
Emory University
Forest Laboratories

Completed

Effect of Nebivolol on Oxidative Stress and Endothelial Progenitor Cells

Hypertension

United States
Brigham and Women's Hospital
Forest Laboratories; Lahey Clinic

Terminated

The Impact of Nebivolol Versus Metoprolol on Quality of Life

Hypertension | Transplant; Failure, Kidney

United States
Mayo Clinic
Forest Laboratories

Terminated

Can Nebivolol Reverse Inappropriate Left Ventricular Mass in Hypertensive Patients? (Inapprop)

Hypertension

United States
Berlin-Chemie AG Menarini Group

Completed

Effects of Nebivolol Versus Metoprolol Succinate on Endothelial Function (NEMENDAS)

Hypertension

Estonia
University of Cincinnati

Terminated

Sympathetic Nervous System Modulation in Hypertension

Hypertension
Mylan Bertek Pharmaceuticals

Completed

Evaluation of the Long-term Safety and Tolerability of Metoprolol Versus Nebivolol in Patients With Hypertension

Hypertension

United States
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, France, China, Israel, Germany, Italy, Hungary, Canada
Gilead Sciences
AstraZeneca

Terminated

Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure

Heart Failure, Congestive

United States
University of Mississippi Medical Center

Terminated

Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate

Hypertension

United States
Weill Medical College of Cornell University
National Institute on Aging (NIA)

Completed

Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
Damanhour Teaching Hospital

Recruiting

Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries

Hypotension Drug-Induced

Egypt
University of Michigan

Completed

Evaluation of Metoprolol Pharmacokinetics in Patients Receiving Hi Flux Hemodialysis

Hemodialysis | Pharmacokinetics

United States
University of Calgary
Vanderbilt University

Active, not recruiting

Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects

Vasovagal Syncope

Canada
AstraZeneca

Completed

Dose Ranging, Safety and Tolerability of TOPROL-XL® Extended-Release Tablets in Hypertensive Pediatric Subjects (307A)

Hypertension

United States, Dominican Republic
AstraZeneca

Completed

307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects

Hypertension

United States, Dominican Republic
Mayo Clinic
AstraZeneca

Completed

A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.

Heart Valve Diseases

United States
Hackensack Meridian Health

Terminated

Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study (PEACE)

COVID-19 | Tachycardia | Dyspnea

United States
Weill Medical College of Cornell University
The New York Community Trust

Completed

Impact of Beta-blockers on Physical Function in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
Medical University of Gdansk

Recruiting

The Efficacy and Safety of Metoprolol as add-on Treatment to Standard of Care in Preventing Cardiomyopathy in Patients With DMD (MeDMD)

Muscular Dystrophy, Duchenne

Poland
Karolinska Institutet
Uppsala University; The Swedish Research Council

Active, not recruiting

Evaluation of Decreased Usage of Betablockers After Myocardial Infarction in the SWEDEHEART Registry (REDUCE-SWEDEHEART)

ST Elevation Myocardial Infarction | Acute Myocardial Infarction | Non-ST Elevation Myocardial Infarction

Sweden
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI); AstraZeneca

Completed

Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease) (P1A1)

Mitral Regurgitation

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); GlaxoSmithKline; AstraZeneca

Completed

Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart (BORG)

Idiopathic Dilated Cardiomyopathy

United States
Steen Hvitfeldt Poulsen

Completed

The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy. (TEMPO)

Hypertrophic Cardiomyopathy

Denmark
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis (CARE Cirrhosis)

Cirrhosis | Cardiac Remodeling | Cirrhotic Cardiomyopathy

Brazil
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study for Metoprolol Succinate ER Tablets 50 mg Under Fasting Condition

Healthy

India
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Metoprolol Succinate ER Tablets, 200 mg Under Fasting Conditions

Healthy

India
AstraZeneca

Completed

Evaluation of Succinate Metoprolol on Heart Rate in the Stable Angina Patients

Angina Pectoris

China
University of Miami
Forest Laboratories

Completed

Nebivolol Versus Metoprolol: Sodium Sensitivity

Hypertension

United States
Forest Laboratories
Mylan Laboratories

Terminated

Study to Evaluate Symptoms in Patients Treated With Nebivolol or Metoprolol Extended-release (ER) for Hypertension

Hypertension

United States
University of Texas Southwestern Medical Center
Forest Laboratories

Completed

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

Hypertension

United States
Bispebjerg Hospital
Odense University Hospital; Zealand University Hospital; Hvidovre University... and other collaborators

Recruiting

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction (DANBLOCK)

ST Elevation Myocardial Infarction | Acute Myocardial Infarction | Non-ST Elevation Myocardial Infarction (nSTEMI)

Denmark
Forest Laboratories

Completed

Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Stage 2 Hypertension | Stage 1 Hypertension

United States
University of Chicago
Forest Laboratories

Completed

Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries (EFFORT)

Hypertension | Diabetes

United States
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Race, Natriuretic Peptides and Physiological Perturbations

Healthy | Pre Hypertension

United States
Emory University
Forest Laboratories

Completed

The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension

High Blood Pressure

United States
Vanderbilt University
Forest Laboratories

Completed

Nebivolol in the Supine Hypertension of Autonomic Failure

Hypertension | Multiple System Atrophy | Pure Autonomic Failure

United States
ARCA Biopharma, Inc.
Medtronic

Completed

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure (GENETIC-AF)

Current or Recent History of Atrial Fibrillation

United States, Canada, Hungary, Netherlands, Poland, Serbia
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metoprolol Succinate Extended Release Tablets 50 mg

Fasting

India
AstraZeneca

Completed

Factorial Study of Metoprolol Succinate TOPROL-XL (324A)

High Blood Pressure (Hypertension).
Bio-innova Co., Ltd

Not yet recruiting

Nebivolol Tablets 5 mg Relative to Nebilet Tablets 5 mg

Healthy Subjects
University Hospital Schleswig-Holstein

Completed

Intravenous Beta-blockade for Improvement of Autonomic Activity

Hypertension | Tachycardia | Heart Rate Variability

Germany
Forest Laboratories

Completed

Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients

Hypertension | Type 2 Diabetes Mellitus

United States, Puerto Rico
Sumitomo Pharma (Suzhou) Co., Ltd.

Completed

Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate (ESAHOM)

Essential Hypertension

China
Boehringer Ingelheim

Terminated

Telmisartan Effectiveness on Left Ventricular Mass Reduction (TELMAR) as Assessed by MRI, in Patients With Mild to Moderate Hypertension

Hypertension
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metoprolol Succinate Extended Release Tablets 200 mg Under Fed Conditions

Fed

India

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