Search clinical trials for: tapentadol HCl

Total 2851 results

Pfizer
Amgen

Completed

Open-Label Study Comparing Etanercept to Conventional Disease Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

Chile, Colombia, Argentina, Mexico, Panama
National Cancer Institute (NCI)

Completed

Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma

Recurrent Adult Hodgkin Lymphoma | Refractory Childhood Hodgkin Lymphoma | Recurrent Childhood Hodgkin Lymphoma

United States, Canada
Nanfang Hospital of Southern Medical University

Completed

Sequential Application of Yisaipu® and DMARDs in Treating Mild-to-Moderate AS

Ankylosing Spondylitis

China
GlaxoSmithKline

Completed

Clinical and Economic Outcomes of Patients Utilizing Combination Therapy for Enlarged Prostates: A Henry Ford Database Assessment

Prostatic Hyperplasia
Karolinska Institutet

Completed

Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT) (SWEFOT)

Rheumatoid Arthritis
Gynecologic Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia

Hydatidiform Mole | Good Prognosis Metastatic Gestational Trophoblastic Tumor | Non-Metastatic Gestational Trophoblastic Tumor | Uterine Corpus Choriocarcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Pancreatic Adenocarcinoma | Metastatic... and other conditions

United States
Janssen-Cilag G.m.b.H

Completed

Long-term Use of Galantamine Versus Nootropics (Memory Enhancing Drugs) in Patients With Alzheimer's Dementia Under Conditions of Daily Routine

Dementia | Alzheimer Disease | Dementia, Vascular
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

Localized Extraskeletal Ewing Sarcoma | Peripheral Primitive Neuroectodermal Tumor of Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues

United States, Canada, Saudi Arabia, Australia, New Zealand, Puerto Rico
National Cancer Institute (NCI)

Recruiting

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Renal Pelvis and Ureter Urothelial Carcinoma

United States
Stanford University
National Cancer Institute (NCI)

Completed

Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

B-cell Adult Acute Lymphoblastic Leukemia (ALL) | Ph-positive Adult Acute Lymphoblastic Leukemia (ALL) | Recurrent Adult Acute Lymphoblastic Leukemia (ALL) | T-cell Adult Acute Lymphoblastic Leukemia (ALL)

United States
UNICANCER

Completed

Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma

Lymphoma

France
University of Pennsylvania
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Alternative Sedation During Bronchoscopy (DEX)

Sedation

United States
Wahba bakhet
Bahteem Specialized Hospital

Completed

Local Anesthesia for Pediatric Cochlear Implant

Anesthesia, Local

Egypt
Tobira Therapeutics, Inc.

Completed

Pharmacokinetic and Safety Study of Cenicriviroc and Acid Reducing Agents When Dosed Alone or in Combination

Healthy

United States
Massachusetts General Hospital
National Institute on Aging (NIA)

Unknown

The Effects of Aging and Estrogen on the Pituitary

Healthy

United States
Fen Li

Recruiting

Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE Patients

Systemic Lupus Erythematosus

China
Qilu Hospital of Shandong University

Recruiting

The Clinical Features and Pregnancy Outcomes of CTD Patients

Connective Tissue Diseases | Pregnancy Related

China
McGill University Health Centre/Research Institute...

Terminated

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain (PRO_GENE_POP)

Postoperative Pain

Canada
National Cancer Institute (NCI)

Terminated

Oblimersen Plus Doxorubicin and Docetaxel in Treating Patients With Metastatic or Locally Advanced Breast Cancer

Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer

United States
National Cancer Institute (NCI)

Completed

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States
Wahba bakhet
Bahteem Specialized Hospital

Completed

Role of Magnesium in Pediatric Cochlear Implant

Anesthesia
Massachusetts General Hospital
National Institutes of Health (NIH)

Unknown

Letrozole Treatment in Normal and GnRH Deficient Women

Healthy Volunteers

United States
Ulrik Grevstad

Completed

Effect of Adductor Canal Block vs. Placebo on Muscle Strength, Mobilisation and Pain After Total Knee Arthroplasty

Knee Replacement Arthroplasty

Denmark
Masonic Cancer Center, University of Minnesota

Completed

MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs

Epidermolysis Bullosa

United States
Jawaharlal Institute of Postgraduate Medical Education...

Completed

Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid Arthritis

Rheumatoid Arthritis

India
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles

Infertility

China
European Organisation for Research and Treatment...
Novartis

Not yet recruiting

177Lu-DOTATATE for Recurrent Meningioma (LUMEN-1)

Recurrent Meningioma
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis (OPTIMIZE)

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Leukemia | Myeloproliferative Neoplasm | Pro-Lymphocytic Leukemia

United States
Abbott

Completed

Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives (HOS)

Hypertension | Obesity
Incyte Corporation

Terminated

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host Disease

United States, Spain, France, Canada, Israel, United Kingdom, Germany, Italy, Denmark, Sweden, Finland, Belgium, Poland, Greece, Austria, Switzerland
National Cancer Institute (NCI)

Suspended

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic Osteosarcoma | Localized Osteosarcoma | High Grade Osteosarcoma | Secondary Osteosarcoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Mesenchymal Chondrosarcoma | Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Malignant Peripheral Nerve Sheath Tumor | PEComa | Synovial Sarcoma | Epithelioid Sarcoma | Alveolar Soft Part Sarcoma | Undifferentiated High Grade Pleomorphic... and other conditions

United States, Canada, Puerto Rico
Bristol-Myers Squibb

Completed

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986263 in Healthy Participants

Fibrosis

United States
Jonsson Comprehensive Cancer Center

Terminated

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Malignant Neoplasm

United States
Northwestern University
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Active, not recruiting

Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma

Diffuse Large B-Cell Lymphoma | Plasmablastic Lymphoma | B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma | Adult Burkitt Lymphoma | MYC Gene Mutation

United States
Fu Wai Hospital, Beijing, China

Not yet recruiting

Anti-inflammatory Therapy for Recurrent In-stent Restenosis

In-stent Restenosis

China
Ain Shams University

Completed

Prophylactic Mirtazapine or Dexamethasone for Post-spinal Anesthesia Shivering

Shivering

Egypt
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor | Adult Kidney Wilms Tumor | Beckwith-Wiedemann Syndrome | Childhood Kidney Wilms Tumor | Diffuse Hyperplastic Perilobar Nephroblastomatosis | Rhabdoid Tumor of the Kidney | Stage V Kidney...

United States, Canada, Australia, New Zealand, Puerto Rico, Israel
National Cancer Institute (NCI)

Active, not recruiting

Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin Lymphoma

Ann Arbor Stage III Non-Hodgkin Lymphoma | Ann Arbor Stage IV Non-Hodgkin Lymphoma | Solid Neoplasm

United States
James Cook University Hospital
Medela AG

Unknown

Enhanced Recovery After Cardiac Surgery (ERAS)

Coronary Artery Disease | Aortic Valve Disease | Cardiac Surgery | Mitral Valve Disease | Tricuspid Valve Disease | Aortic Root Dilatation

United Kingdom
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Recurrent Cervical Carcinoma | Stage IVB Cervical Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome

United States
Oncotherapeutics
Takeda

Completed

Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients

Multiple Myeloma

United States
Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Terminated

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

Minimal Residual Disease | Leukemia, Lymphoblastic, Acute | Leukemia, Myelogenous, Acute

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute... and other conditions

United States
HIV Prevention Trials Network
National Institute on Drug Abuse (NIDA); National Institute of Allergy and...

Enrolling by invitation

INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit (INTEGRA)

HIV Infections | Opioid Use | Drug Use | Opioid-use Disorder

United States
Faculty of Medicine, Sousse

Completed

Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture.

Acute Pain Due to Trauma
Harvard School of Public Health (HSPH)
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

The Mochudi Prevention Project ART Protocol

HIV Infections

Botswana
University of California, San Francisco

Completed

Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers (CKD)

Kidney Disease

United States

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