Clinical Trials Sponsored by H. Lee Moffitt Cancer Center and Research Institute

Total 571 results

H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation

Graft Versus Host Disease

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Phase II Evaluation of FTase Inhibitor (FTI)in Treatment of Advanced Multiple Myeloma

Multiple Myeloma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Comprehensive Cancer Network; Puma Biotechnology, Inc.

Recruiting

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

Gastric Cancer | GastroEsophageal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
University of South Florida; Gateway for Cancer Research

Completed

COGNUTRIN in Breast Cancer Survivors

Breast Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; National Cancer Institute (NCI); Medarex

Completed

Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558

Melanoma (Skin)

United States
H. Lee Moffitt Cancer Center and Research Institute
Incyte Corporation; H. Jean Khoury Cure CML Consortium

Recruiting

Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors

Chronic Myeloid Leukemia, Chronic Phase | Chronic Phase Chronic Myeloid Leukemia

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; National Cancer Institute (NCI); Medarex

Completed

Vaccine Combining Multiple Class I Peptides and Montanide ISA 51VG With Escalating Doses of Anti-PD-1 Antibody Nivolumab or Ipilimumab With Nivolumab For Patients With Resected Stages IIIC/ IV Melanoma

Melanoma (Skin)

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); Florida Department of Health

Completed

Spanish-Language Smoking Cessation Trial

Smoking Cessation

United States
H. Lee Moffitt Cancer Center and Research Institute
M.D. Anderson Cancer Center; National Cancer Institute (NCI); University of Oklahoma

Recruiting

Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS (ProjectENDIT)

Smoking Cessation | HIV

Cambodia
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Prometheus Laboratories

Active, not recruiting

Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer

Kidney Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Horizon Pharma Ireland, Ltd., Dublin Ireland

Completed

Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer

Breast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | Breast Cancer Female

United States
H. Lee Moffitt Cancer Center and Research Institute
Millennium Pharmaceuticals, Inc.; Ortho Biotech, Inc.

Completed

Cyclophosphamide, VELCADE, DOXIL, and Dexamethasone, (CVDD) in Newly Diagnosed Patients With Multiple Myeloma (MM)

Multiple Myeloma

United States
H. Lee Moffitt Cancer Center and Research Institute
BTG International Inc.; Biocompatibles UK Ltd

No longer available

Therasphere for Unresectable Primary or Secondary Liver Neoplasia

Liver Neoplasms | Liver Cancer | HepatoCellular Carcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Regeneron Pharmaceuticals; Genzyme, a Sanofi Company

Recruiting

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.

Active, not recruiting

Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts

Metastatic Melanoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Pfizer; James and Esther King Biomedical Research Program

Completed

Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence

Smoking Cessation | Tobacco Dependence

United States
H. Lee Moffitt Cancer Center and Research Institute
The V Foundation for Cancer Research; Kay Yow Cancer Fund

Completed

Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer

Peritoneal Diseases | Ovarian Diseases | Fallopian Tube Diseases | Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Florida Department of Health; Bankhead-Coley Cancer Research Program

Completed

Latinos CARES (Colorectal Cancer Awareness, Research, Education and Screening)

Colorectal Cancer | Colorectal Carcinoma

United States
Brigham and Women's Hospital
Dana-Farber Cancer Institute; Duke University; H. Lee Moffitt Cancer Center and...

Not yet recruiting

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors (PATH-4)

Hematopoietic Stem Cell Transplant

United States
New Mexico Cancer Care Alliance
Ohio State University Comprehensive Cancer Center; H. Lee Moffitt Cancer Center...

Recruiting

Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer (TCCP)

Cancer | Cancer Risk

United States
H. Lee Moffitt Cancer Center and Research Institute
Johns Hopkins University; National Institutes of Health (NIH)

Withdrawn

Randomized, Phase II Clinical Trial of Sulforaphane in Bladder Cancer Chemoprevention

Bladder Cancer | Urothelial Carcinoma | Bladder Tumor

United States
H. Lee Moffitt Cancer Center and Research Institute
AstraZeneca; Genentech, Inc.; Ohio State University Comprehensive Cancer Center; PatientsLike...

Completed

Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study (ORIEN)

Lung Cancer | Non-small Cell Lung Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Florida Department of Health; Health Choice Network

Recruiting

HPV Multilevel Intervention Strategies Targeting Immunization in Community Settings (HPV MISTICS) (HPV MISTICS)

Human Papilloma Virus (HPV) Vaccine

United States
H. Lee Moffitt Cancer Center and Research Institute
Celgene Corporation; Ortho Biotech Clinical Affairs, L.L.C.

Completed

Pegylated Liposomal Doxorubicin, Low Freq Dexamethasone & Revlimid (Dd-R) in Newly Diagnosed Multiple Myeloma (MM)

Multiple Myeloma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH); Chiron...

Completed

Sequential ATRA Then IL-2 for Modulation of Dendritic Cells and Treatment of Metastatic Renal Cell Cancer

Kidney Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Phase II Clinical Trial of Purified Isoflavones in Prostate Cancer: Comparing Safety, Effectiveness

Prostate Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
National Heart, Lung, and Blood Institute (NHLBI); CTI BioPharma

Completed

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

GVHD | Graft Vs Host Disease

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

Applying mHealth to Tobacco-related Health Disparities (Time2Quit)

Smoking Cessation

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); University of Miami; University of Florida

Recruiting

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Pancreatic Cancer | Pancreatic Cyst

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools (RESET)

Obesity

United States
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital; H. Lee Moffitt...

Completed

Bortezomib in Combination With CC-5013 in Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
H. Lee Moffitt Cancer Center and Research Institute
University of South Florida; National Institutes of Health (NIH)

Completed

Managing Medication-induced Constipation in Cancer: A Clinical Trial

Constipation

United States
H. Lee Moffitt Cancer Center and Research Institute
University of Miami; James and Esther King Biomedical Research Program

Completed

Smoking-cessation: A Spanish-Language Clinical Trial

Smoking Cessation | Tobacco Dependence

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.; The V Foundation...

Active, not recruiting

Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma

Sarcoma

United States
Consumer Wellness Solutions
University of Oklahoma; H. Lee Moffitt Cancer Center and Research Institute; SRI...

Completed

Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes

Smoking Cessation

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH); University...

Completed

Refining and Testing the Electronic Social Network Assessment Program (eSNAP)

Brain Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Janssen Scientific Affairs, LLC

Terminated

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC; Janssen Scientific Affairs, LLC

Completed

Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal Cancers

Colorectal Cancer | Colon Cancer | Colorectal Carcinoma | Colon Disease

United States
H. Lee Moffitt Cancer Center and Research Institute
CG Oncology, Inc.; Richard M. Shulze Family Foundation

Active, not recruiting

Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC

Bladder Cancer | Muscle-Invasive Bladder Carcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Iovance Biotherapeutics, Inc.; Prometheus Inc.

Completed

Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma

Skin Cancer | Melanoma (Skin)

United States
University of Oklahoma
M.D. Anderson Cancer Center; National Cancer Institute (NCI); University of Florida and other collaborators

Recruiting

Mobile Contingency Management for Smoking Cessation (P3)

Smoking Cessation

United States
Dana-Farber Cancer Institute
Massachusetts General Hospital; Brigham and Women's Hospital; Amgen; H. Lee Moffitt...

Completed

AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumor | Carcinoid Tumor | Pancreatic Neuroendocrine Tumor

United States
University of Hawaii
H. Lee Moffitt Cancer Center and Research Institute; Queen's Medical Center; Hawaii...

Recruiting

Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis

Breast Cancer

United States
Douglas Tyler
M.D. Anderson Cancer Center; Merck Sharp & Dohme LLC; Duke University; H. Lee Moffitt...

Completed

Evaluate Safety/Tolerability Intra-Arterial Temozolomide in Patients w/Extremity Melanoma by Isolated Limb Infusion

Melanoma

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institutes of Health (NIH); National Center for Complementary and...

Completed

Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

Tobacco Use | Alcohol Use, Unspecified

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Utilizing Augmented Reality as an Adjunct for Smoking Cessation

Smoking

United States
H. Lee Moffitt Cancer Center and Research Institute
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes

Smoking Cessation

United States
University of Miami
H. Lee Moffitt Cancer Center and Research Institute; James & Esther King Florida...

Completed

Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention

Smoking Cessation

United States
Maastricht Radiation Oncology
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; H. Lee Moffitt...

Completed

Radiomics: a Study of Outcome in Lung Cancer (Radiomics)

Lung Cancer

United States, Italy, Netherlands
H. Lee Moffitt Cancer Center and Research Institute
United States Department of Defense; Sharp Clinical Services, Inc

Recruiting

Using Aspirin to Improve Immunological Features of Ovarian Tumors

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer

United States

Clinical Trials Sponsored by H. Lee Moffitt Cancer Center and Research Institute

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Portugal

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Rare Diseases

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