Search clinical trials for: Fractional Flow Reserve

Total 6870 results

National Cancer Institute (NCI)

Completed

A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage

Extensive Stage Small Cell Lung Carcinoma | Recurrent Small Cell Lung Carcinoma

United States
Southwest Oncology Group
National Cancer Institute (NCI); Roche-Genentech

Completed

S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer

Colorectal Cancer

United States
Centre Hospitalier Régional d'Orléans

Completed

Coronary Flow Reserve (CFR) in Cardiovascular Risk Stratification (CFR-OR)

Ischemic Heart Disease | Ischemia, Myocardial

France
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

Lung-MAP: Taselisib as Therapy in Treating Patients With Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma

United States, Canada
Duke University

Terminated

Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve

Hypertrophic Cardiomyopathy | Non-ischemic Dilated Cardiomyopathy | Microvascular Ischaemia of Myocardium

United States
NSABP Foundation Inc
Hoffmann-La Roche; Genentech, Inc.; Cancer International Research Group (CIRG)

Terminated

BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab (BETH)

Breast Cancer

Korea, Republic of, United States, Canada, Spain, Ireland, Australia, Argentina, China, United Kingdom, Germany, Brazil, Hong Kong, France, Israel, Taiwan, Serbia, Belgium, Thailand, Croatia, Egypt, Italy, Philippines, Bosnia and Herzegovina and more
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group

Completed

Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer

Stage III Colon Cancer | Adenocarcinoma of the Colon

United States, Canada, Puerto Rico
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Lymph Node Removal in Treating Women Who Have Stage I or Stage IIA Breast Cancer

Breast Cancer

United States, Canada, Australia, Ireland
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
Region Skane
AstraZeneca; IHF GmbH - Institut für Herzinfarktforschung; Hippocrates Research; IRW consulting...

Withdrawn

Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention. (AUGEAS)

Diabetes Mellitus | Microvascular Coronary Artery Disease
Columbia University

Terminated

Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve (RFR)

Coronary; Ischemic

United States
Rennes University Hospital

Completed

Low Flow Low Gradient Aortic Stenosis Relevance of the (re)Search for a Contractile Reserve (LOWAS)

Aortic Valve Stenosis

France
Mallinckrodt
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises

Anemia, Sickle Cell

United States
University of Illinois at Chicago
Astellas Pharma Inc

Completed

Assessment of Global Myocardial Perfusion Reserve Using Coronary Sinus Flow Measurements

Coronary Artery Disease

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dual Energy CT for Ischemia Determination Compared to "Gold Standard" Non-Invasive and Invasive Techniques (DECIDE-Gold)

Ischemia

United States
University of Belgrade
Clinical Centre of Serbia

Unknown

Properties of Myocardial Microcirculation in Patients With Different Pathomorphological Substrates, Before and After Recanalization of Coronary Artery CTO

Chronic Total Occlusion of Coronary Artery

Serbia
Northwestern University
Astellas Pharma Global Development, Inc.

Completed

Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI

Myocardial Ischemia

United States
National Cancer Institute (NCI)
NRG Oncology; Radiation Therapy Oncology Group

Completed

Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States, Canada, Israel
National Cancer Institute (NCI)
NRG Oncology

Completed

Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Fallopian Tube Mucinous... and other conditions

United States, Korea, Republic of, Canada, Japan
IRCCS San Raffaele
Servier

Completed

Association Between Coronary Flow Reserve and BH4 Levels in High CV Risk

Hypertension,Essential

Italy
University Hospital Birmingham NHS Foundation Trust

Unknown

Coronary Microvascular Dysfunction in Chronic Kidney Disease (CRIB-FLOW)

Kidney Disease, Chronic | Myocardial Dysfunction

United Kingdom
University of Athens

Completed

Vascular Markers During OGTT in Diabetics and First-degree Relatives

Diabetes Mellitus

Greece
China National Center for Cardiovascular Diseases

Unknown

Risk Factors of Intermediate Coronary Lesion Progression

Coronary Angiography | Coronary Atheroscleroses

China
Federico II University

Completed

Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve (NUTRENDO)

Hypercholesterolemia | Endothelial Dysfunction

Italy
Svendborg Hospital

Completed

Cardiac Function and Microcirculation: Type 2 DIABetes and ECHOcardiographic Changes Over Time (DIABECHO)

Left Ventricular Dysfunction

Denmark
University of Athens

Completed

Changes in Arterial Stiffness and Endothelial Glycocalyx in Patients With Poorly Controlled Diabetes Mellitus Type 1 or Type 2 After Optimization of Antidiabetic Medication.

Diabetes Mellitus

Greece
Ottawa Heart Institute Research Corporation
Ontario HIV Treatment Network

Completed

The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients

Human Immunodeficiency Virus (HIV) | Cardiovascular Disease (CVD)

Canada
Fudan University

Unknown

Predictive Value of Intraoperative Indocyanine Green Clearance Test After Partially Blood Flow Blocking in Postoperative Liver Reserve

Predictive Value of ICG Clearance Measurement During Selective Hepatic Vascular Trial Clamping on Remnant Liver Function After Anatomic Liver Resection

China
Timothy M. Bateman, MD

Completed

Characterization of Myocardial Blood Flow Measurements Using Lexiscan®™ (Regadenoson) (Lexiscan®™) Rubidium-82 Myocardial Perfusion PET: A Temporal-Dependency Investigation

Myocardial Blood Flow Reserve

United States
Groupe Hospitalier Paris Saint Joseph

Completed

Pronostic Impact of Flow Fraction Reserve on Intermediate Stenoses

Coronary Stenosis

France
Ohio State University Comprehensive Cancer Center

Completed

Ohio Colorectal Cancer Prevention Initiative (OCCPI)

Colorectal Cancer | Lynch Syndrome

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma and other conditions

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy

Sexual Dysfunction | Prostate Cancer

United States, Canada
William Beaumont Hospitals
Novartis Pharmaceuticals

Withdrawn

Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II Diabetics

Hypertension | Diabetes Type 2

United States
Brigham and Women's Hospital

Completed

Effects of Ranolazine on Coronary Flow Reserve in Symptomatic Diabetic Patients and CAD (RAND-CFR)

Coronary Artery Disease | Angina | Diabetes, Type I | Diabetes, Type II

United States
Silk Road Medical

Completed

Safety and Efficacy Study for Reverse Flow Used During Carotid Artery Stenting Procedure (ROADSTER)

Carotid Artery Disease

United States, Spain
Brigham and Women's Hospital
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Joslin...

Withdrawn

L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD (LAST-D)

Hemodialysis | End Stage Renal Disease

United States
Ottawa Heart Institute Research Corporation

Terminated

Multi-modality Imaging of Ischemia With 18F-FDG PET and CTA

Myocardial Ischemia

Canada
Ottawa Heart Institute Research Corporation

Completed

Ticagrelor vs Clopidogrel Effect on MFR in CAD Population (PATH)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
GE Healthcare

Completed

123I-mIBG SPECT Imaging

Coronary Artery Disease | Heart Failure

Canada
Ottawa Heart Institute Research Corporation

Completed

Study to Monitor the Effects of Androgen Suppression Treatment on the Heart (AST)

Prostate Cancer

Canada
National Cancer Institute (NCI)

Terminated

Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU

Breast Carcinoma | Stage IV Breast Cancer | Recurrent Breast Carcinoma

United States
Johann Wolfgang Goethe University Hospital
University of Leipzig

Terminated

Effects of Intracoronary Progenitor Cell Therapy on Coronary Flow Reserve After Acute MI (REPAIR-ACS)

Coronary Artery Disease | Acute Myocardial Infarction

Germany
Radiation Therapy Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Southwest... and other collaborators

Completed

Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer

Anal Cancer

United States, South Africa
University of Cincinnati

Terminated

Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics

Acute Decompensated Heart Failure

United States
Istanbul University

Completed

Carotid Intima-media Thickness as Cardiovascular Mortality Predictor in Peritoneal Dialysis Patients

Myocardial Infarction

Turkey
Asan Medical Center
JW Pharmaceutical

Completed

Effect of Pitavastatin on Coronary Flow Reserve in Hypertensive Patients (EPOCH)

Hypertension | Cardiovascular Risk

Korea, Republic of
Helse Stavanger HF
University of Bergen; University of Stavanger

Unknown

The Syndrome X-ercise Study SYNDEX (SYNDEX)

Angina

Norway
Göteborg University

Unknown

Effects of Personalized Training Program on Coronary Flow Reserve in Healthy Volunteers

Coronary Artery Disease | Heart Infarction

Sweden
University Hospital, Caen

Unknown

Myocardial Flow Reserve and 99mTc-DTPA Cardiac Dynamic SPECT (Flow-Heart)

Coronary Artery Disease

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