Search clinical trials for: hypercholesterolemia

Total 1269 results

Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Hypercholesterolemia | Atherosclerotic Cardiovascular Diseases

United States, United Kingdom, Germany, Poland, Netherlands, Canada
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

Atherosclerosis | Hypercholesterolemia | Statin Adverse Reaction

United States
University of Oslo
University of Tromso; University of Minnesota; Boots Norway AS; Mills DA

Unknown

Vascular Lifestyle-Intervention and Screening in Pharmacy (VISA)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Dyslipidemia | Hypercholesterolemia | Hypertensive Disease

Norway
Hospital Clinico Universitario de Santiago
Ministerio de Economía y Competitividad, Spain

Completed

Effect of an Atlantic Diet on Anthropometric Indices and Serum Lipid Profile (GALIAT)

Cardiovascular Disease | Hypercholesterolemia | Adiposity

Spain
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy (ODYSSEY ESCAPE)

Heterozygous Familial Hypercholesterolemia

United States, Germany
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
Medical University of Graz
Sanofi; numares AG

Terminated

Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia (ALIROCKS)

Cardiovascular Diseases | Atherosclerosis | Hypercholesterolemia | Post Prandial Lipemia

Austria
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides

Hypercholesterolemia | Hypertriglyceridemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy Volunteers

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

Hypercholesteremia
Esperion Therapeutics, Inc.

Completed

A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy

Hyperlipidemias

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Canada, United Kingdom, Australia, Mexico
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant (CLEAR Serenity)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Statin Adverse Reaction

United States, Canada
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

Hypercholesterolemia

United States
PepsiCo Global R&D
Glycemic Index Laboratories, Inc

Completed

Oat and Cholesterol

Elevated LDL Cholesterol

Canada
Yerevan State Medical University
Servier

Unknown

Effect of Atorvastatin on Carotid Intima Media Thickness

Hypercholesterolemia | Essential Hypertension
University of Pennsylvania

Completed

Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia, Familial

United States
Duke University
Sanofi; Regeneron Pharmaceuticals

Completed

Patient and Provider Assessment of Lipid Management Registry (PALM)

Smoking | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Peripheral Arterial Disease | Atherosclerosis | Carotid Stenosis | Hypercholesterolemia | Hyperlipidemia | Claudication | Unstable Angina | Coronary Artery Disease (CAD) | Chronic Kidney Disease (CKD) | Angina | Transient Ischemic Attack (TIA) | Myocardial...

United States
Laval University
Amgen

Completed

Lp(a) and Aortic Valve Calcification (FHLPA)

Heterozygous Familial Hypercholesterolemia

Canada
Baylor Research Institute
Regeneron Pharmaceuticals

Unknown

Alirocumab in Patients on a Stable Dialysis Regimen

Hemodialysis | Peritoneal Dialysis | Hypercholesterolemia | Atherosclerotic Disease

United States
University of Manitoba

Completed

Sitosterolemia Metabolism (STAIR7002)

Sitosterolemia

Canada
Ache Laboratorios Farmaceuticos S.A.

Completed

Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia (LANCE)

Dyslipidemia | Hypercholesterolemia

Brazil
Association Tunisienne d'Etude & de Recherche sur...
Dacima Consulting; Direction des Soins de Santé de Base; Biochimie Clinique LR99ES11 and other collaborators

Completed

Dyslipidemia Prevalence, Perception, Treatment, and Awareness in the Tunisian Population (ATERASurvey)

Atherosclerosis | Dyslipidemias | Households | Survey, Family Life

Tunisia
Population Health Research Institute

Terminated

Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial (PAIN-STOP)

Pain, Postoperative

United States, Canada
Golden Biotechnology Corporation

Completed

Trial of Antroquinonol in Patients With Hypercholesterolemia and Hyperlipidemia

Hyperlipidemias

Taiwan
National University of Malaysia
Malaysia Palm Oil Board

Unknown

Supplementation of Oil Palm Phenolics to Healthy Participants (SPIRAL)

Cardiovascular Diseases | Hypercholesterolemia | Hyperlipidemias

Malaysia
Shanghai Junshi Bioscience Co., Ltd.

Completed

A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjects

Hypercholesterolemia

China
Regeneron Pharmaceuticals

Completed

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Homozygous Familial Hypercholesterolemia

United States, Netherlands, Canada
PepsiCo Global R&D

Completed

The Effect of Oats Containing 1.4g Beta Glucan on Fecal Bacterial Population(s) and Plasma Cholesterol in Healthy Adults With Elevated Cholesterol Levels

Microbiome | Plasma Cholesterol | Prebiotic

Ireland
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)

Hypercholesterolemia
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Healthy Subjects

Hypercholesterolaemia

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Effect of Dietary Intervention on LDL-C and Lipoprotein Subclasses Distribution in Patients With Hypercholesterolemia

Disease | Dyslipidemias | Hypercholesterolemia
Charleston Laboratories, Inc

Completed

A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain

Pain | Nausea | Vomiting | Migraine | Aura

United States
University of Arizona

Completed

Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults

Hyperglycemia | Obesity | Hypercholesterolemia | Hypertriglyceridemia

United States
Unity Health Toronto

Unknown

The Effect of Viscous Dietary Fibers on LDL-cholesterol

Hypercholesterolemia | Cardiovascular Risk Factor

Canada
A. Menarini Industrie Farmaceutiche Riunite S.r.l.

Completed

Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol Levels (NATCOL)

Hypercholesterolemia

Italy
Merck Sharp & Dohme LLC

Completed

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020) (REALIZE)

Hyperlipoproteinemia Type II | Hypercholesterolemia, Familial
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY EAST)

Hypercholesterolemia

China, India, Thailand
Yuhan Corporation
Linical Korea

Completed

A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia

Diabetes Mellitus and Hypercholesterolemia

Korea, Republic of
Eli Lilly and Company

Completed

A Study of LY3015014 in Participants With High Cholesterol

Hypercholesterolemia

Poland, Netherlands, United States, Denmark, Canada, Japan, Czechia, Puerto Rico
JW Pharmaceutical

Completed

Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With Hypercholesterolemia (ESPRIT)

Hypercholesterolemia With Type2DM
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia (ODYSSEY J-IVUS)

Hypercholesterolemia | Acute Coronary Syndrome

Japan
Sanofi
Regeneron Pharmaceuticals

Completed

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Hypercholesterolaemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (ODYSSEY KIDS)

Hypercholesterolaemia

Norway, Russian Federation, Sweden, South Africa, Czechia, United States, Canada, France, Netherlands, Spain
Virginia Commonwealth University
Sanofi; Regeneron Pharmaceuticals

Completed

Alirocumab in Patients With Acute Myocardial Infarction

Myocardial Infarction | Hypercholesterolemia

United States
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Lipid-lowering Therapy Individualization

Hypercholesterolemia

Belgium

Search clinical trials for: hypercholesterolemia

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