Clinical Trials Sponsored by Appletree AG

Total 2347 results

Max Zeller Soehne AG

Completed

Pilot Pharmacokinetic Study of a Prolonged-release Formulation of St. John's Wort Extract Ze 117

Healthy

Germany
B. Braun Melsungen AG

Completed

Plasma Volume Replacement (PVR) Therapy With Colloid and Crystalloid Solutions

Plasma Volume Replacement | Surgery of the Pancreatic Head

Germany
Apogenix GmbH

Completed

APG101 in Glioblastoma

Glioblastoma Multiforme

Austria, Germany
B. Braun Melsungen AG

Completed

Safety and Efficacy of Longterm HPN With Two Lipid Emulsions

Malnutrition

Germany
B. Braun Melsungen AG

Completed

Comparison of Two Gelatine Solutions

Hypovolemia

Germany
AOP Orphan Pharmaceuticals AG

Completed

A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. Esmolol

Healthy Volunteers | Pharmacokinetics/Dynamics Study

Czech Republic
Mayo Clinic
Aesculap AG

Completed

HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

Surgical Incisions

United States
Max Zeller Soehne AG

Completed

Investigation of Efficacy and Safety of EPOGAM

Atopic Dermatitis | Neurodermatitis

Switzerland
B. Braun Melsungen AG

Completed

Comparison of Three-chamber-bag Versus Compounded Bag

Parenteral Nutrition for Patients With Proven Insufficient Enteral Resorption

China
B. Braun Melsungen AG

Completed

Safety Profile of Hydroxyethyl Starch

Plasma Volume Replacement

Malaysia, China
B. Braun Melsungen AG

Completed

Feasibility of Blood Glucose Control With the Space TGC System in Postoperative Cardiac Surgery Patients in the ICU (DELIOS 02)

Critical Illness

United Kingdom
B. Braun Melsungen AG

Terminated

Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)

Renal Insufficiency

Germany
B. Braun Melsungen AG

Completed

Blood Glucose Control Over an Extended Glucose Control Range in Postoperative Cardiac Surgery Patients in the Intensive Care Unit (Aldea_02)

Critical Illness

United Kingdom
B. Braun Melsungen AG

Completed

Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)

Catheter Related Bloodstream Infection | Bacteriaemia

Czech Republic
CONKO-Studiengruppe
Fresenius AG

Completed

Parenteral Nutrition Support for Patients With Pancreatic Cancer

Pancreatic Cancer | Cancer Cachexia

Germany
B. Braun Melsungen AG

Completed

Blood Glucose Control With A Software-Algorithm In Intensive Care Unit (ICU) Patients (Aldea _01)

Critical Illness

Austria
B. Braun Melsungen AG

Completed

Effect of a Modified Propofol Preparation on Injection Pain During Induction of Anesthesia in Children

Anesthesia
Carl Zeiss Meditec AG

Recruiting

Evaluation of a Monofocal Intraocular Lens (PRECISE)

Cataract

United States, Mexico
LimmaTech Biologics AG
GlaxoSmithKline

Recruiting

Assessing the Safety, Immune Response, and Early Efficacy of a Candida Vaccine in Women With Recurrent Vulvovaginal Candidiasis: A Randomized Controlled Study

Recurrent Vulvovaginal Candidiasis

Belgium
Sonova AG
Western University

Recruiting

Preference Comparisons for Algorithms to Hear Speech

Hearing Loss

Canada
Aesculap AG
Raylytic GmbH

Recruiting

In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis (COLRAS)

Knee Osteoarthritis | Osteonecrosis | Knee Arthritis | Instability, Joint | Rheumatoid Arthritis of Knee | Deformity Knee | Primary Osteoarthritis of Knee Nos | Secondary Osteoarthritis of Knee Nos

Australia, Germany
Carl Zeiss Meditec AG

Not yet recruiting

Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort (BioBase)

Cataract | Corneal Astigmatism | Corneal Defect | Corneal Deformity | Lens Opacities | Artificial Lens Implant
Aesculap AG
Raylytic GmbH

Recruiting

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical (CERISE)

Degenerative Disc Disease | Spinal Tumor | Degenerative Myelopathy | Spine Fracture | Spinal Instability

Germany
Asklepios proresearch
AG Pregnolia

Recruiting

Impact of Pessary Treatment on Cervical Stiffness Measurement and Birth Outcomes in Patients at Risk for Preterm Birth

Preterm Birth

Germany
Ziemer Ophthalmic Systems AG

Recruiting

LASIK Surgery With a New Laser for the Treatment of Myopia Without Astigmatism (AQUARIUZ2020)

Astigmatism | Myopia

Switzerland
UNICANCER
Roche Pharma AG

Recruiting

Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy (BladderSpar)

Bladder Cancer

France
Aesculap AG
Universitätsklinikum Kiel

Recruiting

Eso-Sponge Registry

Leakage After Esophagectomy | Leakage After Gastrectomy | Perforation of the Esophagus

Germany
B. Braun Melsungen AG

Completed

Evaluation of Performance Over Dwell Time and Safety of the Central-venous Catheters Certofix® Paed

Central Venous Catheter

Germany, Italy
Berner Augenklinik
medignition AG

Enrolling by invitation

Comparison of Rapid Aflibercept and Brolucizumab T&E in wAMD (SPARROW)

Wet Age-related Macular Degeneration

Switzerland
Duke University
Medartis AG

Completed

Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws

Post-traumatic Osteoarthritis, Unspecified Ankle and Foot | Localized, Primary Osteoarthritis of the Ankle and/or Foot

United States
Sonova AG
Vanderbilt University

Completed

Noise Reduction Preferences in Teenagers and Pre-teens

Hearing Loss

United States
Sonova AG
Hoerzentrum Oldenburg

Enrolling by invitation

Effect of Speech Enhancer on Listening Effort With EEG

Listening Effort

Germany
Apogenix GmbH

Terminated

Asunercept for the Treatment of Patients With Moderate to Severe COVID-19 Disease (ASUCOV)

COVID-19

Spain, Germany, France, Italy, South Africa, India, Austria, Georgia, Poland
Drägerwerk AG & Co. KGaA

Terminated

Validation of the Measurement Accuracy of the Tcore Thermometer (T-CORE-PMCF)

Temperature Change, Body

Germany
Pierre Fabre Pharma AG

Completed

Real Life Study on Iron Isomaltoside 1000 in the Treatment of ID in CKD, Heart Failure, ObGyn, IBD, Cancer and Elective Surgery (Real-CHOICE). (Real-CHOICE)

Iron-Deficiency Anemia | Iron-Deficiency

Switzerland
Carl Zeiss Meditec AG

Completed

VISPER: Randomised Comparison of Two OVDs in Cataract Surgery (VISPER)

Cataract Senile

Germany
Lumendo AG
Soteria Danışmanlık

Completed

Comparative Evaluation of the Effectiveness of Root Canal Preparation After Irrigation Using Endodontic Needle and Inertial Cavitation

Post Operative Pain | Root Canal Treatment

Turkey
Carl Zeiss Meditec AG

Completed

Evaluation of a Trifocal Lens

Cataract Senile

Germany
Carl Zeiss Meditec AG

Active, not recruiting

Safety and Effectiveness of VISULAS Green Selective Laser Trabeculoplasty (SLT)

Primary Open-angle Glaucoma

Germany
B. Braun Melsungen AG

Terminated

Gelatin in ICU and Sepsis (GENIUS)

Hypovolemia

Spain, Austria, Germany, Czechia, France
Carl Zeiss Meditec AG

Completed

Safety and Effectiveness of an Hydrophilic Acrylic Intraocular Lens

Cataract Senile

France
Carl Zeiss Meditec AG

Completed

Evaluation of an Hydrophilic Acrylic Intraocular Lens

Cataract Senile

France
Shire
Jerini AG

Completed

EASSI - Evaluation of the Safety of Self-Administration With Icatibant (EASSI)

Hereditary Angioedema

Spain, Argentina, Austria, Denmark, France, Germany, Israel, Italy, Switzerland, United Kingdom
B. Braun Melsungen AG

Withdrawn

Comparison Between Propofol Concentration in Exhaled Breath and Blood Plasma Using the Exhaled Drug Monitor "Edmon" (ProDect)

Anesthesia, Intravenous | Elective Surgical Procedures
be Medical
Biolitec AG

Completed

Treatment of Varicose Veins With the ELVeS® Radial® 2ring Slim Fiber. Are There Limitations?

Varicose Veins

Belgium
GlyPharma Therapeutics
VectivBio AG

Withdrawn

Safety, Tolerability, PK/PD of FE 203799 in Adults With Lymphomas

Lymphoma, Non-Hodgkin's, Adult | Lymphoma, Hodgkin's, Adult
Carl Zeiss Meditec AG

Completed

Visual Outcomes After Presbyopic Lens Exchange (RELAX)

Presbyopia

Germany
Dr. Schär AG / SPA

Completed

Market Research - Acceptability Study for a Range of MCT Products

Epilepsy | Ketosis | Malabsorption | Fatty Acid Oxidation Disorder | Ketogenic Diet

United Kingdom
Carl Zeiss Meditec AG

Unknown

Use of the VisuMax Femtosecond Laser Lenticule Removal Procedure for the Correction of Hyperopia (V1601CI)

Hypermetropia

China, Czechia, France, Germany, India, United Kingdom
Ziemer Ophthalmic Systems AG

Completed

Cataract Surgery: Femto LDV Z8 Versus Conventional (COMFORT)

Cataract

Clinical Trials Sponsored by Appletree AG

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