Search clinical trials for: Pharmacologic actions

Total 95824 results

Glaxo Wellcome

Unknown

Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs

HIV Infections

United States
Gilead Sciences

Completed

A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
Hoffmann-La Roche

Completed

An Open-Label Safety Program for the Use of Zalcitabine (Dideoxycytidine; ddC) in Pediatric Patients With Symptomatic HIV Infection Who Have Failed or Are Intolerant to AZT Monotherapy, or Who Have Completed Other ddC Protocols, or Are Ineligible for Other Ongoing Clinical Studies

HIV Infections

United States
Agouron Pharmaceuticals

Unknown

Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Glaxo Wellcome

Completed

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

HIV Infections

United States
Gilead Sciences

Completed

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

HIV Infections

United States, Puerto Rico
Northwestern Memorial Hospital

Completed

Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children

HIV Infections

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver Transplantation

Graft Versus Host Disease

United States
Glaxo Wellcome

Completed

An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Glaxo Wellcome

Completed

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in HIV-Infected Patients

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy

HIV Infections

United States, Puerto Rico
The Dana Foundation

Completed

A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia

HIV Infections | Cognitive Disorders

United States
Neurex

Completed

A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain

HIV Infections | Pain | Cancer

United States
Wellstat Therapeutics

Terminated

Phase I Study of PN401, Fluorouracil, Leucovorin and CPT-11 in Patients With Solid Tumors

Solid Tumors

United States
Merck Sharp & Dohme LLC

Completed

Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients

HIV Infections

United States
Icahn School of Medicine at Mount Sinai

Completed

Study of Botulinum Toxin in Patients With Primary Hyperhidrosis

Hyperhidrosis

United States
National Center for Research Resources (NCRR)

Unknown

The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A

Thrombosis | Hypercholesterolemia

United States
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Pilot Study of Cytarabine for Refractory Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic
Otsuka America Pharmaceutical

Completed

A Pilot Study of OPC-8212 (Vesnarinone) in Persons With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Pharmacia and Upjohn

Completed

A Study of Delavirdine Mesylate in Combination With Other Anti-HIV Drugs in HIV-Infected Children and Babies

HIV Infections

United States
Pfizer

Completed

Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pharmacia and Upjohn

Completed

A Study of Delavirdine Used Together With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States
Melbourne Health

Completed

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney

Diabetic Nephropathy | Proteinuria | Glomerulonephritis | Kidney Disease

Australia
Glaxo Wellcome

Completed

A Study of 1592U89 in HIV-Infected Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Double-Blind Study of the Efficacy and Safety of Oral Ganciclovir for the Prevention of CMV Disease in People Infected With the Human Immunodeficiency Virus

HIV Infections | Cytomegalovirus Infections

United States
Pharmacia and Upjohn

Completed

A Study of Different Doses of Atevirdine Mesylate Plus Zidovudine in HIV-Positive Patients

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients With HIV-Associated Kidney Disease

HIV Infections | AIDS-Associated Nephropathy

United States
Pfizer

Completed

A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States, Canada
Pfizer

Completed

Comparative Randomized Study of the Efficacy, Safety, and Toleration of Fluconazole Oral Suspension or Nystatin Oral Suspension in the Treatment of Patients With Oropharyngeal Candidiasis in Association With the Acquired Immunodeficiency Syndrome

HIV Infections | Candidiasis, Oral

United States
Merck Sharp & Dohme LLC

Completed

The Effectiveness of HIV RNA Viral Load Testing in Determining Treatment Type in HIV-Infected Patients

HIV Infections

United States
Astra USA

Completed

A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium)

HIV Infections | Cytomegalovirus Retinitis

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder

Tourette Syndrome
National Center for Research Resources (NCRR)
University of Texas

Completed

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Porphyria

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay

Mental Retardation | Developmental Delay Disorder

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Zidovudine Plus Acyclovir in Patients With Early HIV Infection

HIV Infections

United States
Astra USA

Completed

The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatment

HIV Infections | Herpes Simplex

United States
Astra USA

Completed

An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Pfizer

Completed

A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Center for Research Resources (NCRR)
Tufts Medical Center

Completed

Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders

Paralysis, Hyperkalemic Periodic | Paramyotonia Congenita | Hypokalemic Periodic Paralysis
Astra USA

Completed

Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study

HIV Infections | Hypocalcemia | Cytomegalovirus Infections

United States
National Center for Research Resources (NCRR)
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults With Repaired or Palliated Conotruncal Cardiac Defects

Heart Defects, Congenital | Tetralogy of Fallot | Pulmonary Valve Stenosis | Hypoparathyroidism | Pulmonary Atresia | Conotruncal Cardiac Defects
Community Research Initiative of New England

Completed

A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Harvard School of Public Health (HSPH)

Completed

Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil

Leishmaniasis
Johns Hopkins University

Completed

Pilot Study of Cyclophosphamide in Patients With Life-Threatening Systemic Lupus Erythematosus or Antiphospholipid Antibody Syndrome

Systemic Lupus Erythematosus | Antiphospholipid Antibody Syndrome

United States
National Institute on Alcohol Abuse and Alcoholism...

Completed

Ondansetron Treatment for Alcoholism

Alcoholism

United States

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